Expression of typical osteoclast markers by PBMCs after PEG-induced fusion as a model for studying osteoclast differentiation

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Journal of Molecular Histology

• Publication date

  2017-03-25

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s10735-017-9717-4PMID 28343338
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1996influential reference
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  1996cited by this paper
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  1992cited by this paper
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  1991cited by this paper
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  1987cited by this paper
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  1984cited by this paper
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  1979cited by this paper
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  1974cited by this paper
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  year unknowncited by this paper

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