Intervertebral Disc Tissue Engineering Using a Novel Hyaluronic Acid–Nanofibrous Scaffold (HANFS) Amalgam

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Tissue Engineering. Part A

• Publication date

  2008-09-01

• Fields of study

  Medicine, Materials Science, Chemistry, Engineering

• Identifiers
  DOI 10.1089/ten.tea.2008.0215PMID 18707229PMCID PMC2676103
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Fibroblast Growth Factor-2 Maintains the Differentiation Potential of Nucleus Pulposus Cells In Vitro: Implications for Cell-Based Transplantation Therapy

  2007cited by this paper
• Results of the Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemption Study of the ProDisc®-L Total Disc Replacement Versus Circumferential Fusion for the Treatment of 1-Level Degenerative Disc Disease

  2007cited by this paper
• Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering

  2007cited by this paper
• Biological treatment strategies for disc degeneration: potentials and shortcomings

  2007cited by this paper
• Hyaluronan in limb morphogenesis.

  2007cited by this paper
• The In Vivo Biological Effects of Intradiscal Recombinant Human Bone Morphogenetic Protein-2 on the Injured Intervertebral Disc: An Animal Experiment

  2007cited by this paper
• Multidirectional Testing of One- and Two-Level ProDisc-L Versus Simulated Fusions

  2007cited by this paper
• Engineering controllable anisotropy in electrospun biodegradable nanofibrous scaffolds for musculoskeletal tissue engineering.

  2007cited by this paper
• Restoration of Disc Height Loss by Recombinant Human Osteogenic Protein-1 Injection Into Intervertebral Discs Undergoing Degeneration Induced by an Intradiscal Injection of Chondroitinase ABC

  2007cited by this paper
• Clinical experience in cell-based therapeutics: intervention and outcome

  2006cited by this paper
• Safety assessment of intradiscal gene transfer: a pilot study.

  2006cited by this paper
• Back Pain Prevalence and Visit Rates: Estimates From U.S. National Surveys, 2002

  2006cited by this paper
• Chondrocyte Phenotype in Engineered Fibrous Matrix Is Regulated by Fiber Size

  2006cited by this paper
• Is a collagen scaffold for a tissue engineered nucleus replacement capable of restoring disc height and stability in an animal model?

  2006cited by this paper
• Prevention of disc degeneration with growth factors

  2006cited by this paper
• Regeneration of intervertebral disc by mesenchymal stem cells: potentials, limitations, and future direction

  2006cited by this paper
• Sustained Transgene Expression in Intervertebral Disc Cells In Vivo Mediated by Microbubble-Enhanced Ultrasound Gene Therapy

  2006cited by this paper
• In vitro studies of annulus fibrosus disc cell attachment, differentiation and matrix production on PDLLA/45S5 Bioglass composite films.

  2006cited by this paper
• Changes in the utilization of spinal fusion in the United States.

  2006cited by this paper
• Fabrication and characterization of six electrospun poly(alpha-hydroxy ester)-based fibrous scaffolds for tissue engineering applications.

  2006cited by this paper
• Small Intestinal Submucosa as a Potential Bioscaffold for Intervertebral Disc Regeneration

  2006cited by this paper
• Tissue‐engineered intervertebral disc and chondrogenesis using human nucleus pulposus regulated through TGF‐β1 in platelet‐rich plasma

  2006cited by this paper
• Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast.

  2005cited by this paper
• Electrospun degradable polyesterurethane membranes: potential scaffolds for skeletal muscle tissue engineering.

  2005cited by this paper
• Differentiation of Mesenchymal Stem Cells Transplanted to a Rabbit Degenerative Disc Model: Potential and Limitations for Stem Cell Therapy in Disc Regeneration

  2005cited by this paper
• Correlation Between Range of Motion and Outcome After Lumbar Total Disc Replacement: 8.6-Year Follow-up

  2005cited by this paper
• A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells.

  2005cited by this paper
• Clinical results of Maverick lumbar total disc replacement: two-year prospective follow-up.

  2005cited by this paper
• Biocompatible Nanofiber Matrices for the Engineering of a Dermal Substitute for Skin Regeneration

  2005cited by this paper
• Induction of Intervertebral Disc–Like Cells From Adult Mesenchymal Stem Cells

  2005cited by this paper
• Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold.

  2005cited by this paper
• Artificial disc replacement: the new solution for discogenic low back pain?

  2005cited by this paper
• Differentiation of Mesenchymal Stem Cells Towards a Nucleus Pulposus-like Phenotype In Vitro: Implications for Cell-Based Transplantation Therapy

  2004cited by this paper
• Design and evaluation of the FlexiCore metal-on-metal intervertebral disc prosthesis.

  2004cited by this paper
• The effectiveness of polyethylene versus titanium particles in inducing osteolysis in vivo

  2004cited by this paper
• Stem cell regeneration of the nucleus pulposus.

  2004cited by this paper
• Gene Transfer of the Catabolic Inhibitor TIMP-1 Increases Measured Proteoglycans in Cells from Degenerated Human Intervertebral Discs

  2003cited by this paper
• Biological response of chondrocytes cultured in three-dimensional nanofibrous poly(epsilon-caprolactone) scaffolds.

  2003cited by this paper
• Biological response of chondrocytes cultured in three-dimensional nanofibrous poly(ϵ-caprolactone) scaffolds†

  2003cited by this paper
• Formation of a mandibular condyle in vitro by tissue engineering.

  2003cited by this paper
• An Experimental Study of the Regeneration of the Intervertebral Disc With an Allograft of Cultured Annulus Fibrosus Cells Using a Tissue-Engineering Method

  2003cited by this paper
• Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration.

  2003cited by this paper
• Evaluation of indication-based use of transpedicular instrumentations with different rigidity for lumbar spinal fusion: a prospective pilot study with 3 years of follow-up

  2003cited by this paper
• The Potential and Limitations of a Cell-Seeded Collagen/Hyaluronan Scaffold to Engineer an Intervertebral Disc-Like Matrix

  2003cited by this paper
• Disc Chondrocyte Transplantation in a Canine Model: A Treatment for Degenerated or Damaged Intervertebral Disc

  2003cited by this paper
• Spinal Implant Debris-Induced Osteolysis

  2003cited by this paper
• Intradiscal application of hyaluronic acid in the non-human primate lumbar spine: radiological results

  2003cited by this paper
• Proteoglycans Synthesized by Canine Intervertebral Disc Cells Grown in a Type I Collagen–Glycosaminoglycan Matrix

  2002cited by this paper
• Human marrow-derived mesenchymal progenitor cells

  2002cited by this paper
• TGF-beta1 calcium signaling increases alpha5 integrin expression in osteoblasts.

  2002cited by this paper
• Lower Back Pain and Disorders of Intervertebral Discs

  2002influential reference
• TGF‐β1 calcium signaling increases α5 integrin expression in osteoblasts

  2002cited by this paper
• Electrospun nanofibrous structure: a novel scaffold for tissue engineering.

  2002cited by this paper
• Three-dimensional cartilage formation by bone marrow-derived cells seeded in polylactide/alginate amalgam.

  2001cited by this paper
• 2001 Volvo Award Winner in Clinical Studies: Lumbar Fusion Versus Nonsurgical Treatment for Chronic Low Back Pain: A Multicenter Randomized Controlled Trial From the Swedish Lumbar Spine Study Group

  2001cited by this paper
• Cultivation of porcine cells from the nucleus pulposus in a fibrin/hyaluronic acid matrix

  2000cited by this paper
• Epidemiology of low back pain.

  2000cited by this paper
• Hyaluronan Distribution in the Human and Canine Intervertebral Disc and Cartilage Endplate

  1999cited by this paper
• Tissue engineering.

  1998cited by this paper
• Tissue engineering.

  1993cited by this paper
• Initial characterization of the metabolism of intervertebral disc cells encapsulated in microspheres

  1992cited by this paper
• Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue.

  1986cited by this paper
• Nutrition of the intervertebral disc: effect of fluid flow on solute transport.

  1982cited by this paper
• Nutrition of the intervertebral disk. An in vivo study of solute transport.

  1977influential reference
• Study Group

  1971cited by this paper
• Campbell's Operative Orthopaedics

  1956cited by this paper

• Design and Ex Vivo Evaluation of a PCLA Degradable Device To Improve Annulus Fibrosus Repair.

  2025cites this paper
• Advances in Annulus Fibrosus Repair: Hybrid Scaffolds and Fabrication Techniques for Regeneration.

  2025cites this paper
• Electrospun 3D nanofibrous materials and their applications in orthopaedics

  2024cites this paper
• An injectable in situ hydrogel platform for sustained drug release against Glioblastoma.

  2024cites this paper
• Regenerative therapies for lumbar degenerative disc diseases: a literature review

  2024cites this paper
• Applications of Scaffolds in Tissue Engineering: Current Utilization and Future Prospective.

  2023cites this paper
• Hybrid materials with continuous mechanical property gradients that can be 3D printed

  2023cites this paper
• Notochordal cells: A potential therapeutic option for intervertebral disc degeneration

  2023cites this paper
• Engineering GliaTrap: a biodegradable non-swelling hydrogel with tuned release of CXCL12 to attract migrating glioblastoma cells

  2023cites this paper
• Biomimetic Design of 3D Fibrous Mesh Reinforced Hydrogel Replicating the Form and Function of the Intervertebral Disc

  2023cites this paper
• Elastic Fibers in the Intervertebral Disc: From Form to Function and toward Regeneration

  2022cites this paper
• Biomechanical evaluation of a novel repair strategy for intervertebral disc herniation in an ovine lumbar spine model

  2022cites this paper
• Innovative Biological Treatment Methods for Degenerative Disc Disease.

  2022cites this paper
• New strategies for the treatment of intervertebral disc degeneration: cell, exosome, gene, and tissue engineering.

  2022cites this paper
• Advances in Tissue Engineering for Disc Repair

  2021cites this paper
• A Polycaprolactone (PCL)-Supported Electrocompacted Aligned Collagen Type-I Patch for Annulus Fibrosus Repair and Regeneration.

  2021cites this paper
• Three-Dimensional-Printed Flexible Scaffolds Have Tunable Biomimetic Mechanical Properties for Intervertebral Disc Tissue Engineering.

  2021cites this paper
• Multiscale Regulation of the Intervertebral Disc: Achievements in Experimental, In Silico, and Regenerative Research

  2021cites this paper
• Electrospun Polysaccharidic Textiles for Biomedical Applications

  2021cites this paper
• Tissue Engineering of Human Intervertebral Disc: A Concise Review

  2021cites this paper
• High strength HA-PEG/NAGA-Gelma double network hydrogel for annulus fibrosus rupture repair

  2021cites this paper
• Advances and Prospects in Biomaterials for Intervertebral Disk Regeneration

  2021cites this paper
• Tissue engineering for regeneration and replacement of the intervertebral disk

  2020cites this paper
• Preparation of Chitosan-Polycaprolactone (PCL) Composite Nanofiber as Potential for Annulus Fibrosus Regeneration

  2020cites this paper
• Advanced Strategies for the Regeneration of Lumbar Disc Annulus Fibrosus

  2020cites this paper
• Sacrificial Fibers Improve Matrix Distribution and Micromechanical Properties in a Tissue-Engineered Intervertebral Disc.

  2020cites this paper
• An Injectable Hyaluronan–Methylcellulose (HAMC) Hydrogel Combined with Wharton’s Jelly-Derived Mesenchymal Stromal Cells (WJ-MSCs) Promotes Degenerative Disc Repair

  2020cites this paper
• The Functional Role of Interface Tissue Engineering in Annulus Fibrosus Repair: Bridging Mechanisms of Hydrogel Integration with Regenerative Outcomes.

  2020cites this paper
• Nanotechnology for the Treatment of Spinal Cord Injury

  2020cites this paper
• Scaffold-Free Tissue Engineering with Aligned Bone Marrow Stromal Cell Sheets to Recapitulate the Microstructural and Biochemical Composition of Annulus Fibrosus.

  2020cites this paper
• Generation of an in vitro model of the outer annulus fibrosus‐cartilage interface

  2020cites this paper
• Gel and cells: A promising reparative strategy for degenerated intervertebral discs

  2020cites this paper
• The Role of Hyaluronic Acid in Intervertebral Disc Regeneration

  2020cites this paper
• Development of annulus fibrosus tissue construct with hydrogel coils containing pre-conditioned mesenchymal stem cell

  2020cites this paper
• Use of Stem Cells in Spinal Treatments

  2019cites this paper
• Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review

  2019cites this paper
• Intervertebral Disc Nucleus Repair: Hype or Hope?

  2019cites this paper
• Mechanobiology of annulus fibrosus and nucleus pulposus cells in intervertebral discs

  2019cites this paper
• Disordered Mechanical Stress and Tissue Engineering Therapies in Intervertebral Disc Degeneration

  2019cites this paper
• Nanotechnology in Spine Surgery: A Current Update and Critical Review of the Literature.

  2019cites this paper
• Hyaluronic acid cryogels with non-cytotoxic crosslinker genipin

  2019cites this paper
• Hyaluronan-Based Nanofibers: Fabrication, Characterization and Application

  2019cites this paper
• Biaxial mechanics of 3D fiber deposited ply-laminate scaffolds for soft tissue engineering part I: Experimental evaluation.

  2019cites this paper
• Efficacy of HYADD®4-G single intra-discal injections in a rabbit model of intervertebral disc degeneration

  2019cites this paper
• Engineering a biomimetic integrated scaffold for intervertebral disc replacement.

  2019cites this paper
• Resorbable plating system stabilizes tissue‐engineered intervertebral discs implanted ex vivo in canine cervical spines

  2018cites this paper
• Marrow-Isolated Adult Multilineage Inducible (MIAMI) and Annulus Fibrosus Cell Co-Cultures on Electrospun Polycaprolactone Scaffolds for Intervertebral Disc Tissue Engineering

  2018cites this paper
• Physiology and Engineering of the Graded Interfaces of Musculoskeletal Junctions.

  2018cites this paper
• A novel electrospun-aligned nanoyarn/three-dimensional porous nanofibrous hybrid scaffold for annulus fibrosus tissue engineering

  2018cites this paper
• Nanofibrous scaffolds for biomedical applications.

  2018cites this paper
• Promise, progress, and problems in whole disc tissue engineering

  2018cites this paper
• Nature-Inspired Hydrogels with Soft and Stiff Zones that Exhibit a 100-Fold Difference in Elastic Modulus.

  2018cites this paper
• Towards the scale up of tissue engineered intervertebral discs for clinical application.

  2018cites this paper
• Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc

  2018cites this paper
• Applications of bioresorbable polymers in the skeletal systems (cartilages, tendons, bones)

  2017cites this paper
• 7.15 Intervertebral Disc

  2017cites this paper
• Biomimetic Nanofibers as Artificial Stem Cell Niche

  2017cites this paper
• Mesenchymal Stem Cells: A Future Option for Intervening Disease Management

  2017cites this paper
• Differentiation of adipose stem cells seeded towards annulus fibrosus cells on a designed poly(trimethylene carbonate) scaffold prepared by stereolithography

  2017influential citation
• 3D Printing Polymers with Supramolecular Functionality for Biological Applications.

  2017cites this paper
• Application of polymeric nanofibers in medical designs, part III: Musculoskeletal and urological tissues

  2017cites this paper
• Tissue Engineering of the Intervertebral Disc’s Annulus Fibrosus: A Scaffold-Based Review Study

  2017cites this paper
• Non-Covalent Interactions in the Design and Performance of Macromolecules for Biological Technologies

  2017cites this paper
• 6.11 Biomaterials for Replacement and Repair of the Meniscus and Annulus Fibrosus

  2017cites this paper
• Biomaterials for intervertebral disc regeneration and repair.

  2017cites this paper
• 2.21 Xenogenic Tissues and Biomaterials for the Skeletal System

  2017cites this paper
• Total disc replacement using tissue-engineered intervertebral discs in the canine cervical spine

  2017cites this paper
• Bioengineered three-dimensional diseased intervertebral disc model revealed inflammatory crosstalk.

  2017cites this paper
• Applications of 3D printing in the management of severe spinal conditions

  2017cites this paper
• Advances in biological therapy for nucleus pulposus regeneration.

  2016cites this paper
• Repair and Regenerative Therapies of the Annulus Fibrosus of the Intervertebral Disc.

  2016cites this paper
• Stem Cells in Skeletal Tissue Engineering: Technologies and Models.

  2016cites this paper
• Mesenchymal stem cells in regenerative medicine: Focus on articular cartilage and intervertebral disc regeneration.

  2016cites this paper
• Cell-based Therapies for Degenerative Disc Diseases

  2016cites this paper
• Future advances for treating lumbar disc herniation and degeneration: Nucleus replacement, annular repair, and biologics

  2016cites this paper
• Construction Strategy and Progress of Whole Intervertebral Disc Tissue Engineering

  2016influential citation
• Hyaluronic Acid and Its Derivatives in Coating and Delivery Systems: Applications in Tissue Engineering, Regenerative Medicine and Immunomodulation

  2016cites this paper
• Biological Treatment Approaches for Degenerative Disk Disease: A Literature Review of In Vivo Animal and Clinical Data

  2016cites this paper
• Hyaluronic Acid (HA) Scaffolds and Multipotent Stromal Cells (MSCs) in Regenerative Medicine

  2016cites this paper
• Cell Regeneration: Current Knowledge and Evolutions

  2016cites this paper
• Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms

  2016cites this paper
• Intervertebral Disc Engineering through Exploiting Mesenchymal Stem Cells: Progress and Perspective.

  2016cites this paper
• Thermally triggered injectable hydrogel, which induces mesenchymal stem cell differentiation to nucleus pulposus cells: Potential for regeneration of the intervertebral disc.

  2016cites this paper
• Design and development of anisotropic laminate scaffolds of electrospun polycaprolactone for annulus fibrosus tissue engineering applications

  2016cites this paper
• Testing the efficacy of GDF6 as a biological therapy for the treatment of intervertebral disc degeneration

  2016cites this paper
• Synthesis, Structural and Micromechanical Properties of 3D Hyaluronic Acid-Based Cryogel Scaffolds.

  2016cites this paper
• [Progress and challenges in tissue engineering of intervertebral disc annulus fibrosus].

  2016cites this paper
• Decellularized allogeneic intervertebral disc: natural biomaterials for regenerating disc degeneration

  2016cites this paper
• Harnessing the Potential of Mesenchymal Stem Cells for IVD Regeneration.

  2015cites this paper
• Clinical Translation in Tissue Engineering—The Surgeon’s View

  2015cites this paper
• Nuclear Connectivity in Mesenchymal Stem Cell Differentiation and its Role in Mechanotransduction

  2015cites this paper
• Construction of a tissue engineered intervertebral disc with high biological activity using an allogeneic intervertebral disc supplemented with transfected nucleus pulposus cells expressing exogenous dopamine beta-hydroxylase.

  2015cites this paper
• Hyaluronic Acid-Based Biomaterials

  2015cites this paper
• Dose-Dependent Response of Tissue-Engineered Intervertebral Discs to Dynamic Unconfined Compressive Loading

  2015cites this paper
• An injectable hydrogel for nucleus pulposus regeneration

  2015cites this paper
• Comparison of Engineered Peptide-Glycosaminoglycan Microfibrous Hybrid Scaffolds for Potential Applications in Cartilage Tissue Regeneration

  2015cites this paper
• A Structurally and Functionally Biomimetic Biphasic Scaffold for Intervertebral Disc Tissue Engineering

  2015cites this paper
• A combined biomaterial and cellular approach for annulus fibrosus rupture repair.

  2015cites this paper
• 'Cell or Not to Cell' that is the Question: For Intervertebral Disc Regeneration?

  2015cites this paper
• Injectable, high-density collagen gels for annulus fibrosus repair: An in vitro rat tail model.

  2015cites this paper