Nevus Size and Number Are Associated with Telomere Length and Represent Potential Markers of a Decreased Senescence In vivo

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Cancer Epidemiology, Biomarkers and Prevention

• Publication date

  2007-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1158/1055-9965.EPI-07-0152PMID 17627017
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human telomere biology: pitfalls of moving from the laboratory to epidemiology.

  2006cited by this paper
• Chromosomal telomere attrition as a mechanism for the increased risk of epithelial cancers and senescent phenotypes in type 2 diabetes

  2006cited by this paper
• Genome-wide search for nevus density shows linkage to two melanoma loci on chromosome 9 and identifies a new QTL on 5q31 in an adult twin cohort.

  2006cited by this paper
• From Melanocytes to Melanoma

  2006cited by this paper
• Familial Melanoma Genes, Melanocyte Immortalization, and Melanoma Initiation

  2006cited by this paper
• The genetics of melanoma.

  2006influential reference
• Mapping genetic loci that determine leukocyte telomere length in a large sample of unselected female sibling pairs.

  2006cited by this paper
• Oncogene-induced cell senescence--halting on the road to cancer.

  2006influential reference
• Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study

  2006cited by this paper
• Cellular senescence in naevi and immortalisation in melanoma: a role for p16?

  2006cited by this paper
• The UK Experience

  2005cited by this paper
• BRAFE600-associated senescence-like cell cycle arrest of human naevi

  2005cited by this paper
• Telomere attrition as ageing biomarker.

  2005cited by this paper
• Obesity, cigarette smoking, and telomere length in women.

  2005cited by this paper
• The Senescent Side of Tumor Suppression

  2005cited by this paper
• Telomeres, stem cells, senescence, and cancer.

  2004cited by this paper
• Significant role for p16INK4a in p53-independent telomere-directed senescence.

  2004cited by this paper
• Short Telomeres Are Associated With Increased Carotid Atherosclerosis in Hypertensive Subjects

  2004cited by this paper
• Melanocytic nevi, solar keratoses, and divergent pathways to cutaneous melanoma.

  2003cited by this paper
• Association between telomere length in blood and mortality in people aged 60 years or older.

  2003cited by this paper
• Telomere Length in the Newborn

  2002cited by this paper
• p16(Ink4a) in melanocyte senescence and differentiation.

  2002cited by this paper
• The St. Thomas' UK Adult Twin Registry

  2002cited by this paper
• Evaluation of telomerase activity in cutaneous melanocytic proliferations.

  2000cited by this paper
• Melanoma genetics: an update with focus on the CDKN2A(p16)/ARF tumor suppressors.

  2000cited by this paper
• Telomere length in different tissues of elderly patients.

  2000cited by this paper
• Genetics of risk factors for melanoma: an adult twin study of nevi and freckles.

  2000cited by this paper
• A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: a maximum-likelihood combined linkage and association analysis in twins and their sibs.

  1999cited by this paper
• The genetics of hereditary melanoma and nevi

  1999cited by this paper
• Increase in telomerase activity during progression of melanocytic cells from melanocytic naevi to malignant melanomas

  1999cited by this paper
• The association between naevi and melanoma in populations with different levels of sun exposure: a joint case-control study of melanoma in the UK and Australia.

  1998cited by this paper
• The atypical-mole syndrome and predisposition to melanoma.

  1998cited by this paper
• Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages.

  1998cited by this paper
• The genetics of melanoma: the UK experience

  1998cited by this paper
• Risk of cutaneous melanoma in relation to the numbers, types and sites of naevi: a case-control study.

  1996cited by this paper
• Dysplastic nevi as a melanoma risk factor in patients with familial melanoma

  1994cited by this paper
• Genetic determination of telomere size in humans: a twin study of three age groups.

  1994cited by this paper
• Simplified Calculation of Body-Surface Area

  1987cited by this paper
• Simplified calculation of body-surface area.

  1987cited by this paper
• Melanocytic naevi and melanoma: an epidemiological perspective

  1987cited by this paper
• Book ReviewNeuroanatomy: An atlas of structures, sections and systems

  1987cited by this paper
• Risk factors for cutaneous melanoma in Queensland.

  1986cited by this paper
• A Wilcoxon-type test for trend.

  1985cited by this paper
• A Wilcoxon-type test for trend.

  1985cited by this paper
• Natural regression of the melanocytic nevus.

  1959cited by this paper

• Assessing lung cancer progression and survival with infrared spectroscopy of blood serum

  2025cites this paper
• A Cross‐Sectional Study of Platelet‐to‐Lymphocyte Ratio in Relation to Pigment Cell Nevi and Atypical Mole Syndrome

  2025cites this paper
• An Anthropometric Study of Total Body Nevus Counts, Height, Sex, and Age Differences

  2025cites this paper
• Telomere length and skin cancer risk: A systematic review and meta-analysis of melanoma, basal cell carcinoma and squamous cell carcinoma

  2025cites this paper
• Cell Senescence and the Genetics of Melanoma Development

  2024cites this paper
• POT1 and multiple primary melanomas: the dermatological phenotype

  2024cites this paper
• Distinct senescence mechanisms restrain progression of dysplastic nevi

  2024cites this paper
• Genetic testing for familial melanoma.

  2024cites this paper
• Review: Are moles senescent?

  2024cites this paper
• Melanoma and Glioblastoma—Not a Serendipitous Association

  2023cites this paper
• Distinct senescence mechanisms restrain progression of dysplastic nevi

  2023cites this paper
• Skin Cancer Microenvironment: What We Can Learn from Skin Aging?

  2023cites this paper
• Association of Telomere Length With Risk of Disease and Mortality.

  2022cites this paper
• Melanocytic naevi, melanocytomas and emerging concepts.

  2022cites this paper
• Biology and genetics of acquired and congenital melanocytic naevi.

  2022cites this paper
• Impact of a personal history of cutaneous squamous cell carcinoma in the overall survival of cutaneous melanoma patients

  2022cites this paper
• Genetically determined cutaneous nevi and risk of cancer

  2021cites this paper
• Alterations of the pigmentation system in the aging process

  2021cites this paper
• Examining Evidence For A Causal Association Between Telomere Length & Nevus Count.

  2021cites this paper
• Autoimmune alleles at the major histocompatibility locus modify melanoma susceptibility

  2021cites this paper
• Identification and clinical evaluation of senescence-associated markers to distinguish melanocytic nevi from melanomas

  2020cites this paper
• Age and Melanocytic Lesions.

  2020cites this paper
• Height, nevus count, and risk of cutaneous malignant melanoma: results from two large cohorts of US women.

  2020cites this paper
• Natural history of naevi: a two‐wave study

  2020cites this paper
• It’s Not All Sunshine: Non-sun-related Melanoma Risk-factors

  2020cites this paper
• Genome-wide association meta-analyses combining multiple risk phenotypes provides insights into the genetic architecture of cutaneous melanoma susceptibility

  2020cites this paper
• Genetic determinants of telomere length and cancer risk.

  2020cites this paper
• Cutaneous nevi and internal cancer risk: Results from two large prospective cohorts of US women

  2020cites this paper
• Genes determining nevus count and dermoscopic appearance in Australian melanoma cases and controls.

  2020cites this paper
• Clinical Genetics and Risk Assessment of Melanoma

  2020cites this paper
• Detection of cell‐free circulating BRAFV600E by droplet digital polymerase chain reaction in patients with and without melanoma under dermatological surveillance

  2020cites this paper
• Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma

  2019cites this paper
• Age favoured overall survival in a large population-based Danish patient cohort treated with anti-PD1 immune checkpoint inhibitor for metastatic melanoma

  2019cites this paper
• Prioritization and comprehensive analysis of genes associated with melanoma

  2019cites this paper
• New and evolving concepts of melanocytic nevi and melanocytomas

  2019cites this paper
• Melanoma risk stratification of individuals with a high‐risk naevus phenotype – A pilot study

  2019cites this paper
• Age favoured overall survival in a large population-based Danish patient cohort treated with anti-PD1 immune checkpoint inhibitor for metastatic melanoma.

  2019cites this paper
• Telomere length, telomerase reverse transcriptase promoter mutations, and melanoma risk

  2018cites this paper
• The relationship between naevus count, memory function and telomere length in the Twins UK cohort

  2018cites this paper
• Vitamin D in melanoma: Controversies and potential role in combination with immune check-point inhibitors.

  2018cites this paper
• Molecular Epidemiology of Melanoma

  2018cites this paper
• Effect of Age on Melanoma Risk, Prognosis and Treatment Response.

  2018cites this paper
• Telomere length and survival in primary cutaneous melanoma patients

  2018cites this paper
• Pathways from senescence to melanoma: focus on MITF sumoylation

  2017cites this paper
• Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

  2017cites this paper
• Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma

  2017cites this paper
• Epigenomic studies of twins for cancer and cancer risk factors

  2017cites this paper
• Molecular Genetics of Melanoma Progression

  2017cites this paper
• Common Delayed Senescence of Melanocytes from Multiple Primary Melanoma Patients

  2017cites this paper
• Positive Association Between Vitamin D Serum Levels and Naevus Counts.

  2017cites this paper
• Melanocytic nevi and melanoma: unraveling a complex relationship

  2017cites this paper
• Genetics of melanoma progression: the rise and fall of cell senescence

  2016cites this paper
• Heritability of naevus patterns in an adult twin cohort from the Brisbane Twin Registry: a cross‐sectional study

  2016cites this paper
• No association between telomere length-related loci and number of cutaneous nevi

  2016cites this paper
• Prediction of high naevus count in a healthy U.K. population to estimate melanoma risk

  2016cites this paper
• Skin phenotypes can offer some insight about the association between telomere length and cancer susceptibility.

  2016cites this paper
• Shorter telomere length in Europeans than in Africans due to polygenetic adaptation.

  2016cites this paper
• What Is New in Melanoma Genetics and Treatment?

  2016cites this paper
• Nevus count associations with pigmentary phenotype, histopathological melanoma characteristics and survival from melanoma

  2016cites this paper
• Hereditary melanoma: Update on syndromes and management: Emerging melanoma cancer complexes and genetic counseling.

  2016cites this paper
• Differences in telomere length between sporadic and familial cutaneous melanoma

  2016cites this paper
• Large Acquired Nevus or Dysplastic Nevus: What's in the Name of a Nevus?

  2016cites this paper
• Lessons from genome-wide studies of melanoma: towards precision medicine

  2016cites this paper
• A Case of Huge Intradermal Melanocytic Nevus of the External Auditory Canal Orifice

  2016cites this paper
• Reconstructive Flaps After Salvage Nasopharyngectomy

  2016cites this paper
• Genetic epidemiology of melanoma

  2016cites this paper
• Telomere length and the risk of cutaneous melanoma and non-melanoma skin cancer: a review of the literature and meta-analysis.

  2015cites this paper
• Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort

  2015cites this paper
• Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

  2015cites this paper
• Telomere length and common disease: study design and analytical challenges

  2015cites this paper
• Height and Bone Mineral Density Are Associated with Naevus Count Supporting the Importance of Growth in Melanoma Susceptibility

  2015cites this paper
• A murine model for the development of melanocytic nevi and their progression to melanoma

  2015cites this paper
• Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling

  2015cites this paper
• High nevus counts confer a favorable prognosis in melanoma patients

  2015cites this paper
• Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

  2015cites this paper
• Development of lens-based probe designs and methods for depth-sensitive optical measurements

  2015cites this paper
• The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length

  2014cites this paper
• Common Acquired and Atypical/Dysplastic Melanocytic Nevi

  2014cites this paper
• Telomerase promoter mutations in cancer: an emerging molecular biomarker?

  2014cites this paper
• FACTORS ASSOCIATED WITH NEVUS VOLATILITY IN EARLY ADOLESCENCE

  2014cites this paper
• The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length

  2014cites this paper
• Version Other version Link to publication record in King ' s Research Portal

  2014cites this paper
• Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk.

  2014cites this paper
• Vitamin D and cancer

  2013cites this paper
• Telomere Length and the Risk of Cutaneous Malignant Melanoma in Melanoma-Prone Families with and without CDKN2A Mutations

  2013cites this paper
• Patients with Multiple Nevi

  2013cites this paper
• Clonal BRAF mutations in melanocytic nevi and initiating role of BRAF in melanocytic neoplasia.

  2013cites this paper
• Telomere length and risk of melanoma, squamous cell carcinoma, and basal cell carcinoma.

  2013cites this paper
• Melanoma. Shall we move away from the sun and focus more on embryogenesis, body weight and longevity?☆

  2013cites this paper
• Monitoring patients with multiple nevi.

  2013cites this paper
• Wnt signaling potentiates nevogenesis

  2013cites this paper
• Sun Exposure, Sunbeds and Sunscreens and Melanoma. What Are the Controversies?

  2013cites this paper
• Senescence evasion in melanoma progression: uncoupling of DNA-damage signaling from p53 activation and p21 expression

  2013cites this paper
• The use of the twin model to investigate the genetics and epigenetics of skin diseases with genomic, transcriptomic and methylation data

  2012cites this paper
• Nevus senescence: An update

  2012cites this paper
• Risk factors for actinic keratosis in eight European centres: a case–control study

  2012cites this paper
• Melanocytic naevi and basal cell carcinoma: is there an association?

  2012cites this paper
• On the Interplay of Telomeres, Nevi and the Risk of Melanoma

  2012influential citation
• Nevogenesis: Changing Theories

  2012cites this paper
• TERT-CLPTM1L Polymorphism rs401681 Contributes to Cancers Risk: Evidence from a Meta-Analysis Based on 29 Publications

  2012cites this paper