miR-542-3p inhibits colorectal cancer cell proliferation, migration and invasion by targeting OTUB1.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  American Journal of Cancer Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 28123857PMCID PMC5250690
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination

  2016cited by this paper
• MicroRNAs in colorectal carcinoma - from pathogenesis to therapy

  2016cited by this paper
• miR-542-3p suppresses invasion and metastasis by targeting the proto-oncogene serine/threonine protein kinase, PIM1, in melanoma.

  2016cited by this paper
• miR-542-3p inhibits the growth and invasion of colorectal cancer cells through targeted regulation of cortactin.

  2016cited by this paper
• MiR‐622 inhibited colorectal cancer occurrence and metastasis by suppressing K‐Ras

  2016cited by this paper
• OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer

  2016cited by this paper
• MicroRNA-542-3p suppresses cellular proliferation of bladder cancer cells through post-transcriptionally regulating survivin.

  2016cited by this paper
• miR‐542‐3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin

  2015cited by this paper
• MicroRNA-320a inhibits proliferation and invasion of breast cancer cells by targeting RAB11A.

  2015cited by this paper
• NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay.

  2015cited by this paper
• OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance

  2015cited by this paper
• Annual report on status of cancer in China, 2011.

  2015cited by this paper
• OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo

  2015cited by this paper
• Decreased expression of miR-542-3p exerts growth inhibitory functions in esophageal cancer.

  2015cited by this paper
• RLIP76-dependent suppression of PI3K/AKT/Bcl-2 pathway by miR-101 induces apoptosis in prostate cancer.

  2015cited by this paper
• Hispidulin prevents hypoxia-induced epithelial-mesenchymal transition in human colon carcinoma cells.

  2015cited by this paper
• Global cancer statistics, 2012

  2015cited by this paper
• MicroRNA-542-3p Suppresses Tumor Cell Invasion via Targeting AKT Pathway in Human Astrocytoma*

  2015cited by this paper
• MicroRNA-542-3p suppresses cell growth of gastric cancer cells via targeting oncogene astrocyte-elevated gene-1

  2014cited by this paper
• Colon cancer bears overexpression of OTUB1.

  2014cited by this paper
• MiR-378 is an independent prognostic factor and inhibits cell growth and invasion in colorectal cancer

  2014cited by this paper
• OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer

  2014influential reference
• MicroRNA‐542‐3p inhibits tumour angiogenesis by targeting Angiopoietin‐2

  2014cited by this paper
• Overexpression of microRNA-183 in human colorectal cancer and its clinical significance

  2014cited by this paper
• The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer

  2012cited by this paper
• UCHL1 acts as a colorectal cancer oncogene via activation of the β-catenin/TCF pathway through its deubiquitinating activity.

  2012cited by this paper
• Genetic disruption of USP9X sensitizes colorectal cancer cells to 5-fluorouracil

  2012cited by this paper
• Aberrant expression of USP22 is associated with liver metastasis and poor prognosis of colorectal cancer

  2011cited by this paper
• Induction of growth arrest by miR‐542‐3p that targets survivin

  2010cited by this paper
• Defining the human deubiquitinating enzyme interaction landscape.

  2009cited by this paper
• MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

  2009cited by this paper
• MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

  2009cited by this paper
• MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells.

  2009cited by this paper
• MicroRNAs: Target Recognition and Regulatory Functions

  2009cited by this paper
• Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation.

  2007cited by this paper
• Regulation of the p27Kip1 tumor suppressor by miR‐221 and miR‐222 promotes cancer cell proliferation

  2007cited by this paper
• Physical activity and survival after colorectal cancer diagnosis.

  2006cited by this paper
• Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation

  2002cited by this paper

• Targeting the miR-493-5p/OTUB1 Axis to Mitigate Mitochondrial Dysfunction in Diabetic Cardiomyopathy.

  2025cites this paper
• OTU deubiquitinases in cancer pathogenesis and precision therapy.

  2025cites this paper
• Otubain deubiquitinases: Multi-layered regulators of cell fate, development, and stress responses across kingdoms

  2025cites this paper
• Primary Cilia Formation Mediated by Hsa_Circ_0005185/OTUB1/RAB8A Complex Inhibits Prostate Cancer Progression by Suppressing Hedgehog Signaling Pathway

  2025cites this paper
• CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2

  2024cites this paper
• OTUB1 Promotes Glioblastoma Growth by Inhibiting the JAK2/STAT1 Signaling Pathway

  2024cites this paper
• MicroRNA-542-3p targets Pten to inhibit the myoblasts proliferation but suppresses myogenic differentiation independent of targeted Pten

  2024cites this paper
• OTUB1-mediated inhibition of ubiquitination: a growing list of effectors, multiplex mechanisms, and versatile functions

  2024cites this paper
• Expression and Clinical Significance of TIGIT in Primary Breast Cancer

  2023cites this paper
• Comparison of Oncogenes, Tumor Suppressors, and MicroRNAs Between Schizophrenia and Glioma: The Balance of Power.

  2023cites this paper
• LINC00092 Enhances LPP Expression to Repress Thyroid Cancer Development via Sponging miR-542-3p

  2023cites this paper
• Non-invasive diagnosis of endometriosis: immunologic and genetic markers.

  2022cites this paper
• Efficacy of glucose transporter inhibitors for the treatment of ERRα-overexpressed colorectal cancer.

  2022cites this paper
• Ubiquitin specific peptidase 11 as a novel therapeutic target for cancer management

  2022cites this paper
• Silencing LncRNA CASC9 inhibits proliferation and invasion of colorectal cancer cells by MiR-542-3p/ILK

  2022cites this paper
• CircRBM33 downregulation inhibits hypoxia-induced glycolysis and promotes apoptosis of breast cancer cells via a microRNA-542-3p/HIF-1α axis

  2022cites this paper
• CircRBM33 downregulation inhibits hypoxia-induced glycolysis and promotes apoptosis of breast cancer cells via a microRNA-542-3p/HIF-1α axis

  2022cites this paper
• Integrative Transcriptomic Network Analysis of Butyrate Treated Colorectal Cancer Cells

  2021cites this paper
• Long noncoding RNA TUG1 regulates the progression of colorectal cancer through miR-542-3p/TRIB2 axis and Wnt/β-catenin pathway

  2021cites this paper
• MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma

  2021influential citation
• Deubiquitinating enzyme OTUB1 in immunity and cancer: Good player or bad actor?

  2021cites this paper
• circ_PTN contributes to -cisplatin resistance in glioblastoma via PI3K/AKT signaling through the miR-542-3p/PIK3R3 pathway

  2021cites this paper
• CircRNA_002178 as a ceRNA promotes the development of colorectal cancer by regulating miR-542-3p/CREB1.

  2021cites this paper
• Interaction of microRNAs with sphingosine kinases, sphingosine-1 phosphate, and sphingosine-1 phosphate receptors in cancer

  2021cites this paper
• Effect of lncRNA XLOC_005950 knockout by CRISPR/Cas9 gene editing on energy metabolism and proliferation in osteosarcoma MG63 cells mediated by hsa-miR-542-3p

  2021cites this paper
• Hsa-miR-5581-3p and Hsa-miR-542-3p Target the F8 Gene in Hemophilia A without F8 Mutations

  2021cites this paper
• Micro-RNA miR-542-3p suppresses decidualization by targeting ILK pathways in human endometrial stromal cells

  2021cites this paper
• The functions and regulation of Otubains in protein homeostasis and diseases.

  2021cites this paper
• OTUB1 Promotes Progression and Proliferation of Prostate Cancer via Deubiquitinating and Stabling Cyclin E1

  2020cites this paper
• Circ‐PGAM1 promotes malignant progression of epithelial ovarian cancer through regulation of the miR‐542‐3p/CDC5L/PEAK1 pathway

  2020cites this paper
• Screening and Interaction Analysis of Key Genes in miR-542-3p Over-Expressed Osteosarcoma Cells by Bioinformatics.

  2020cites this paper
• MiR-542-3p Suppresses Neuroblastoma Cell Proliferation and Invasion by Downregulation of KDM1A and ZNF346

  2020cites this paper
• microRNA in Extracellular Vesicles Released by Damaged Podocytes Promote Apoptosis of Renal Tubular Epithelial Cells

  2020cites this paper
• Long noncoding RNA LINC00963 induces NOP2 expression by sponging tumor suppressor miR-542-3p to promote metastasis in prostate cancer

  2020cites this paper
• MicroRNA-103a Curtails the Stemness of Non-Small Cell Lung Cancer Cells by Binding OTUB1 via the Hippo Signaling Pathway

  2020influential citation
• Deubiquitinase Otubain 1 as a Cancer Therapeutic Target

  2020cites this paper
• MicroRNA silencing of CNN1 and CNN2 protein family members regulates biology processes in colorectal cancer by targeting the p53 signal pathway

  2020cites this paper
• MicroRNA-103a curtails the stemness of non-small cell lung cancer cells by binding to OTUB1 through the Hippo signaling pathway

  2020cites this paper
• MicroRNA-542-3p represses OTUB1 expression to inhibit migration and invasion of esophageal cancer cells

  2019influential citation
• Functional analysis of deubiquitylating enzymes in tumorigenesis and development.

  2019cites this paper
• Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma

  2019cites this paper
• Long non-coding RNA CASC15 favors tumorigenesis and development of ovarian cancer via sponging miR-542-3p.

  2019cites this paper
• IL-15 in autoimmunity and cancer: O-tu-b or not O-tu-b?

  2019cites this paper
• hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles

  2019cites this paper
• Tideglusib, a prospective alternative to nonoxynol-9 contraceptive

  2019cites this paper
• MicroRNA-338-3p inhibits the progression of bladder cancer through regulating ETS1 expression.

  2019cites this paper
• MicroR-542-3p can mediate ILK and further inhibit cell proliferation, migration and invasion in osteosarcoma cells

  2019cites this paper
• MiR-542-3p, a microRNA targeting CDK14, suppresses cell proliferation, invasiveness, and tumorigenesis of epithelial ovarian cancer.

  2019cites this paper
• Otubain 1: a non-canonical deubiquitinase with an emerging role in cancer.

  2019cites this paper
• ERRα Regulates OTUB1 Expression to Promote Colorectal Cancer Cell Migration

  2019cites this paper
• Resveratrol Induces Endothelial Progenitor Cells Angiogenesis via MiR-542-3p by Targeting Angiopoietin-2 and Involves in Recanalization of Venous Thrombosis

  2019cites this paper
• MiR-629-5p promotes colorectal cancer progression through targetting CXXC finger protein 4

  2018cites this paper
• OTUB1 protein suppresses mTOR complex 1 (mTORC1) activity by deubiquitinating the mTORC1 inhibitor DEPTOR

  2018cites this paper
• Exosomal miRNAs species in the blood of small cell and non-small cell lung cancer patients

  2018cites this paper
• Prognostic value of microRNAs in colorectal cancer: a meta-analysis

  2018cites this paper
• Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer

  2018cites this paper
• Analysis of microRNA Expression Profiles Induced by Yiqifumai Injection in Rats with Chronic Heart Failure

  2018cites this paper
• miR‑501‑3p sensitizes glioma cells to cisplatin by targeting MYCN.

  2018cites this paper
• [The Role of MicroRNAs in Colorectal Cancer].

  2017cites this paper
• MiR-421 inhibits the malignant phenotype in glioma by directly targeting MEF2D.

  2017cites this paper
• MiR-542-3p exerts tumor suppressive functions in non-small cell lung cancer cells by upregulating FTSJ2.

  2017cites this paper
• MiR-542-3p inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting UBE3C.

  2017cites this paper