Neuroprotective role of bradykinin because of the attenuation of pro‐inflammatory cytokine release from activated microglia

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Neurochemistry

• Publication date

  2007-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1471-4159.2006.04339.xPMID 17402969
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Neuroprotective Function of the PGE2 EP2 Receptor in Cerebral Ischemia

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• Kinin receptors in cultured rat microglia.

  2004cited by this paper
• [Bradykinin receptors: towards new pathophysiological roles].

  2003cited by this paper
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  2003cited by this paper
• Expression and function of bradykinin receptors in microglia.

  2003cited by this paper
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• Induction of bradykinin B1 hypotensive receptors in rats by lipopolysaccharide.

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• Kinins and kinin receptors in the nervous system.

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