The rotavirus surface protein VP8 modulates the gate and fence function of tight junctions in epithelial cells

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Cell Science

• Publication date

  2004-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/jcs.01425PMID 15494377
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tight junction formation in cultured epithelial cells (MDCK)

  2005influential reference
• Characterization of the tight junction protein ZO-2 localized at the nucleus of epithelial cells.

  2004cited by this paper
• Multistep entry of rotavirus into cells: a Versaillesque dance.

  2004cited by this paper
• Tumor necrosis factor alpha disrupts tight junction assembly.

  2004cited by this paper
• A new principle for tight junction modulation based on occludin peptides.

  2003cited by this paper
• Tight junction proteins.

  2003cited by this paper
• Global Illness and Deaths Caused by Rotavirus Disease in Children

  2003cited by this paper
• E-Cadherin and tight junctions between epithelial cells of different animal species

  2002cited by this paper
• VLA-2 (α2β1) Integrin Promotes Rotavirus Entry into Cells but Is Not Necessary for Rotavirus Attachment

  2002cited by this paper
• VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment.

  2002cited by this paper
• A 22-Amino Acid Synthetic Peptide Corresponding to the Second Extracellular Loop of Rat Occludin Perturbs the Blood-Testis Barrier and Disrupts Spermatogenesis Reversibly In Vivo1

  2001cited by this paper
• Multifunctional strands in tight junctions

  2001cited by this paper
• Introduction: Evolution of Ideas on the Tight Junction

  2001cited by this paper
• Junction adhesion molecule is a receptor for reovirus.

  2001cited by this paper
• Differential Infection of Polarized Epithelial Cell Lines by Sialic Acid-Dependent and Sialic Acid-Independent Rotavirus Strains

  2001cited by this paper
• Rotavirus-Induced Structural and Functional Alterations in Tight Junctions of Polarized Intestinal Caco-2 Cell Monolayers

  2000cited by this paper
• Integrin alpha(v)beta(3) mediates rotavirus cell entry.

  2000cited by this paper
• Apically Exposed, Tight Junction-Associated β1-Integrins Allow Binding and YopE-Mediated Perturbation of Epithelial Barriers by Wild-Type Yersinia Bacteria

  2000cited by this paper
• Molecular physiology and pathophysiology of tight junctions V. assault of the tight junction by enteric pathogens.

  2000cited by this paper
• Selective Membrane Permeabilization by the Rotavirus VP5* Protein Is Abrogated by Mutations in an Internal Hydrophobic Domain

  2000cited by this paper
• Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells.

  2000cited by this paper
• Rotavirus alters paracellular permeability and energy metabolism in Caco-2 cells.

  2000cited by this paper
• Enhancing paracellular permeability by modulating epithelial tight junctions.

  2000cited by this paper
• The VP5 Domain of VP4 Can Mediate Attachment of Rotaviruses to Cells

  2000influential reference
• Integrins α2β1 and α4β1 Can Mediate SA11 Rotavirus Attachment and Entry into Cells

  2000cited by this paper
• Integrin alpha2beta1 mediates the cell attachment of the rotavirus neuraminidase-resistant variant nar3.

  2000cited by this paper
• Integrin α2β1 Mediates the Cell Attachment of the Rotavirus Neuraminidase-Resistant Variant nar3

  2000influential reference
• Integrin αvβ3 mediates rotavirus cell entry

  2000cited by this paper
• Cell-Cell Interactions

  2000cited by this paper
• Small Synthetic Peptides Homologous to Segments of the First External Loop of Occludin Impair Tight Junction Resealing

  1999cited by this paper
• The Cytoplasmic Domains of a β1 Integrin Mediate Polarization in Madin-Darby Canine Kidney Cells by Selective Basolateral Stabilization*

  1998cited by this paper
• Vinculin but not alpha-actinin is a target of PKC phosphorylation during junctional assembly induced by calcium.

  1998cited by this paper
• Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor.

  1998cited by this paper
• Rotavirus contains integrin ligand sequences and a disintegrin-like domain that are implicated in virus entry into cells.

  1997cited by this paper
• Occludin confers adhesiveness when expressed in fibroblasts.

  1997cited by this paper
• A Synthetic Peptide Corresponding to the Extracellular Domain of Occludin Perturbs the Tight Junction Permeability Barrier

  1997cited by this paper
• Isolation of a Common Receptor for Coxsackie B Viruses and Adenoviruses 2 and 5

  1997cited by this paper
• Functional and structural analysis of the sialic acid-binding domain of rotaviruses

  1997cited by this paper
• Biotinylation and assessment of membrane polarity: caveats and methodological concerns.

  1995influential reference
• Species specificity and interspecies relatedness in VP4 genotypes demonstrated by VP4 sequence analysis of equine, feline, and canine rotavirus strains.

  1994cited by this paper
• Uncoupling of the molecular 'fence' and paracellular 'gate' functions in epithelial tight junctions

  1993influential reference
• Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins.

  1993cited by this paper
• Integrins: versatility, modulation, and signaling in cell adhesion.

  1992cited by this paper
• Assembly and sealing of tight junctions: Possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin

  1991cited by this paper
• The VP8 fragment of VP4 is the rhesus rotavirus hemagglutinin.

  1991cited by this paper
• Increased β-Lactoglobulin Absorption during Rotavirus Enteritis in Infants: Relationship to Sugar Permeability

  1991cited by this paper
• Effect of Rotavirus Infection and Malnutrition on Uptake of a Dietary Antigen in the Intestine

  1990cited by this paper
• Role of calcium in tight junction formation between epithelial cells.

  1990influential reference
• Intestinal permeability changes in acute gastroenteritis: effects of clinical factors and nutritional management.

  1989cited by this paper
• A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses.

  1989cited by this paper
• Rotavirus gene structure and function.

  1989cited by this paper
• Comparison of human, simian, and bovine rotaviruses for requirement of sialic acid in hemagglutination and cell adsorption.

  1989cited by this paper
• The major human rhinovirus receptor is ICAM-1.

  1989cited by this paper
• The polarized distribution of an apical cell surface glycoprotein is maintained by interactions with the cytoskeleton of Madin-Darby canine kidney cells

  1988influential reference
• Reassembly of the occluding junctions in a renal cell line with characteristics of proximal tubular cells.

  1986cited by this paper
• Occluding junctions and paracellular pathways studied in monolayers of MDCK cells.

  1983cited by this paper
• Structural polypeptides of simian rotavirus SA11 and the effect of trypsin

  1981cited by this paper
• Proteolytic enhancement of rotavirus infectivity: molecular mechanisms

  1981cited by this paper
• Experimental modulation of occluding junctions in a cultured transporting epithelium

  1980influential reference
• The effect of trypsin on the growth of rotavirus.

  1978cited by this paper

• Extracellular Vesicles from Probiotic and Beneficial Escherichia coli Strains Exert Multifaceted Protective Effects Against Rotavirus Infection in Intestinal Epithelial Cells

  2026influential citation
• Convergent mechanisms of epithelial cell structure manipulation by intestinal pathogens

  2025cites this paper
• The role and implication of rotavirus VP8∗ in viral infection and vaccine development.

  2025cites this paper
• Design of multi-epitope vaccine against porcine rotavirus using computational biology and molecular dynamics simulation approaches

  2024cites this paper
• Viral gastroenteritis.

  2024cites this paper
• A Copper-Binding Peptide with Therapeutic Potential against Alzheimer′s Disease: From the Blood–Brain Barrier to Metal Competition

  2024cites this paper
• Interferon-λ3 alleviates intestinal epithelium injury induced by porcine rotavirus in mice.

  2023cites this paper
• Peptide permeation enhancers for improving oral bioavailability of macromolecules

  2022cites this paper
• Polyubiquitination and SUMOylation Sites Regulate the Stability of ZO-2 Protein and the Sealing of Tight Junctions

  2022cites this paper
• Extracellular Vesicles (EVs) Are Copurified with Feline Calicivirus, yet EV-Enriched Fractions Remain Infectious

  2022cites this paper
• Protective effects of the postbiotic deriving from cow’s milk fermentation with L. paracasei CBA L74 against Rotavirus infection in human enterocytes

  2022cites this paper
• Circulative Transmission of Cileviruses in Brevipalpus Mites May Involve the Paracellular Movement of Virions

  2022cites this paper
• Micronutrient Improvement of Epithelial Barrier Function in Various Disease States: A Case for Adjuvant Therapy

  2022cites this paper
• Virus interactions with the actin cytoskeleton—what we know and do not know about SARS-CoV-2

  2022cites this paper
• Treading a HOSTile path: Mapping the dynamic landscape of host cell–rotavirus interactions to explore novel host-directed curative dimensions

  2021cites this paper
• Virus-associated disruption of mucosal epithelial tight junctions and its role in viral transmission and spread

  2021influential citation
• Porcine Sapovirus-Induced Tight Junction Dissociation via Activation of the RhoA/ROCK/MLC Signaling Pathway

  2021cites this paper
• Formulation strategies to improve the efficacy of intestinal permeation enhancers.

  2021cites this paper
• Classical swine fever virus infection suppresses claudin-1 expression to facilitate its replication in PK-15 cells.

  2021cites this paper
• Imaging therapeutic peptide transport across intestinal barriers

  2021cites this paper
• Tight junction protein claudin-2 promotes cell entry of Bombyx mori cypovirus

  2021cites this paper
• Regulatory roles of claudin-1 in cell adhesion and microvilli formation.

  2021cites this paper
• Titanium dioxide nanoparticles exaggerate respiratory syncytial virus-induced airway epithelial barrier dysfunction

  2020cites this paper
• E7 oncoprotein from human papillomavirus 16 alters claudins expression and the sealing of epithelial tight junctions

  2020influential citation
• Intestinal permeation enhancers to improve oral bioavailability of macromolecules: reasons for low efficacy in humans

  2020cites this paper
• Alteration of cell junctions during viral infection

  2020cites this paper
• Histo-blood group antigens as divergent factors of groups A and C rotaviruses circulating in humans and different animal species

  2020influential citation
• Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability

  2019cites this paper
• Characterization of monoclonal antibodies recognizing each extracellular loop domain of occludin.

  2019cites this paper
• Host Invasion by Pathogenic Amoebae: Epithelial Disruption by Parasite Proteins

  2019cites this paper
• Human-rat chimeric anti-occludin monoclonal antibodies inhibit hepatitis C virus infection.

  2019cites this paper
• Co-infection with porcine bocavirus and porcine circovirus 2 affects inflammatory cytokine production and tight junctions of IPEC-J2 cells

  2018cites this paper
• Rotavirus: Genetics, pathogenesis and vaccine advances

  2018cites this paper
• Relationship between G proteins coupled receptors and tight junctions

  2018cites this paper
• Early Porcine Sapovirus Infection Disrupts Tight Junctions and Uses Occludin as a Coreceptor

  2018influential citation
• Dengue virus enters and exits epithelial cells through both apical and basolateral surfaces and perturbs the apical junctional complex.

  2018cites this paper
• Rotavirus-Induced Early Activation of the RhoA/ROCK/MLC Signaling Pathway Mediates the Disruption of Tight Junctions in Polarized MDCK Cells

  2018cites this paper
• HbAHP‐25 attenuates HIV‐1 gp120 mediated inflammation and barrier dysfunction

  2018cites this paper
• Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function.

  2017cites this paper
• Lysosomal Degradation of Junctional Proteins

  2017cites this paper
• Porcine Rotaviruses: Epidemiology, Immune Responses and Control Strategies

  2017cites this paper
• 7 Claudins and Germ Cell Tumors

  2017cites this paper
• Entamoeba histolytica EhCP112 Dislocates and Degrades Claudin-1 and Claudin-2 at Tight Junctions of the Intestinal Epithelium

  2017influential citation
• pVHL suppresses Akt/β-catenin-mediated cell proliferation by inhibiting 14-3-3ζ expression.

  2017cites this paper
• AMP-activated protein kinase: a therapeutic target in intestinal diseases

  2017cites this paper
• Title Safety and efficacy of sodium caprate in promoting oral drugabsorption : from in vitro to the clinic

  2017cites this paper
• Dynamic interplay between adhesion surfaces in carcinomas: Cell-cell and cell-matrix crosstalk.

  2016cites this paper
• Rotavirus Attachment, Internalization, and Vesicular Traffic

  2016cites this paper
• Claudins in viral infection: from entry to spread

  2016influential citation
• Human Intestinal Barrier Function in Health and Disease

  2016cites this paper
• Intestinal permeation enhancers for oral peptide delivery.

  2016cites this paper
• Strategies that Target Tight Junctions for Enhanced Drug Delivery.

  2016cites this paper
• Using peptides to increase transport across the intestinal barrier.

  2016cites this paper
• Pharmaceutical Targeting of the Brain.

  2016cites this paper
• Polarized rotavirus entry and release from differentiated small intestinal cells.

  2016cites this paper
• Tight junctions: from simple barriers to multifunctional molecular gates

  2016cites this paper
• A study of PDZ protein expression during the human papillomavirus life cycle

  2015cites this paper
• Claudins and pathogenesis of viral infection.

  2015cites this paper
• Loss of EP2 Receptor Subtype in Colonic Cells Compromise Epithelial Barrier Integrity by Altering Claudin-4

  2014cites this paper
• Signalling at tight junctions during epithelial differentiation and microbial pathogenesis

  2014cites this paper
• Applications of omics approaches to the development of microbiological risk assessment using RNA virus dose–response models as a case study

  2014cites this paper
• Transmissible gastroenteritis virus and porcine epidemic diarrhoea virus infection induces dramatic changes in the tight junctions and microfilaments of polarized IPEC-J2 cells

  2014cites this paper
• RhoGTPases, actomyosin signaling and regulation of the epithelial Apical Junctional Complex.

  2014cites this paper
• Tight junction, selective permeability, and related diseases.

  2014cites this paper
• Formulation strategies to improve oral peptide delivery.

  2014cites this paper
• Virus-host interactions : entry and replication of Crimean-Congo hemorrhagic fever virus

  2014cites this paper
• Genome-wide RNAi screen reveals a role for the ESCRT complex in rotavirus cell entry

  2013cites this paper
• Lactobacillus rhamnosus GG on Rotavirus-Induced Injury of Ileal Epithelium in Gnotobiotic Pigs

  2013cites this paper
• Cyprinid herpesvirus 3 infection disrupts the skin barrier of common carp (Cyprinus carpio L.).

  2013cites this paper
• Cleavage of transmembrane junction proteins and their role in regulating epithelial homeostasis

  2013cites this paper
• HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR 5

  2013cites this paper
• Cleavage of transmembrane junction proteins and their role in regulating epithelial homeostasis

  2013cites this paper
• Expression and purification of rotavirus structural proteins VP5* and VP8* in bacteria E. coli BL21(DE3)

  2013cites this paper
• Environmental Factors and Type 1 Diabetes Mellitus in Pediatric Age Group

  2013cites this paper
• Intestinal Epithelial CD98 Directly Modulates the Innate Host Response to Enteric Bacterial Pathogens

  2013cites this paper
• R5 HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5

  2013cites this paper
• Expresión y purificación de las proteínas estructurales VP5* y VP8* de rotavirus en bacterias E. coli BL21(DE3)

  2013cites this paper
• Tight Junctions in Cancer Metastasis

  2013cites this paper
• Densovirus Crosses the Insect Midgut by Transcytosis and Disturbs the Epithelial Barrier Function

  2013cites this paper
• Intestinal barrier of carp (Cyprinus carpio L.) during a cyprinid herpesvirus 3-infection: molecular identification and regulation of the mRNA expression of claudin encoding genes.

  2013cites this paper
• Regulation of Tight Junctions for Therapeutic Advantages

  2013cites this paper
• The Reversible Increase in Tight Junction Permeability Induced by Capsaicin Is Mediated via Cofilin-Actin Cytoskeletal Dynamics and Decreased Level of Occludin

  2013cites this paper
• The interaction between claudin-1 and dengue viral prM/M protein for its entry.

  2013cites this paper
• Concepts and mechanisms: crossing host barriers.

  2013cites this paper
• Rotavirus capsid surface protein VP4-coated Fe(3)O(4) nanoparticles as a theranostic platform for cellular imaging and drug delivery.

  2012cites this paper
• Expression of claudins 7 and 18 in pancreatic ductal adenocarcinoma: association with features of differentiation

  2012cites this paper
• Role of tight junctions in hepatitis C virus infection.

  2012cites this paper
• Chapter 7 – The Developing Gastrointestinal Tract in Relation to Autoimmune Disease, Allergy, and Atopy

  2012cites this paper
• Germ Cell Tumor

  2012cites this paper
• Tight junctions in skin: new perspectives.

  2012cites this paper
• Studies of intestinal barrier functions of common carp, Cyprinus carpio, under feeding modulation and pathogen challenge

  2012cites this paper
• Claudins and Germ Cell Tumors

  2012cites this paper
• Tight Junctions and the Intestinal Barrier

  2012cites this paper
• Claudins and other tight junction proteins.

  2012cites this paper
• Caractérisation d'inhibiteurs de l'entrée du Virus de l'Hépatite C

  2012cites this paper
• Peptides as tight junction modulators.

  2011cites this paper
• Claudins in lung diseases

  2011cites this paper
• Mucin dynamics and enteric pathogens

  2011cites this paper
• Die Auswirkung von Hypoxie auf die intestinale Tight Junction: Rolle des Transkriptionsfaktors Hypoxia Inducible Factor 1 (HIF-1)

  2011cites this paper
• Impenetrable barriers or entry portals? The role of cell–cell adhesion during infection

  2011cites this paper