Cardiac fibroblasts are essential for beneficial myocardial healing but also cause detrimental adverse remodeling following myocardial infarction. The mechanical properties of the infarcted myocardium and border regions display temporal and spatial characteristics that regulate different aspects of the profibrotic cardiac fibroblast phenotypes.
Mechanical regulation of cardiac fibroblast profibrotic phenotypes
K. Herum,Jonas Choppe,Aditya Kumar,A. Engler,A. McCulloch
Published 2017 in Molecular Biology of the Cell
ABSTRACT
PUBLICATION RECORD
- Publication year
2017
- Venue
Molecular Biology of the Cell
- Publication date
2017-07-07
- Fields of study
Biology, Medicine, Engineering
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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