PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1

A. Pines,Mischa G. Vrouwe,J. Marteijn,Dimitris Typas,M. S. Luijsterburg,Medine Cansoy,P. Hensbergen,A. Deelder,A. de Groot,Syota Matsumoto,K. Sugasawa,N. Thoma,W. Vermeulen,H. Vrieling,L. Mullenders

Published 2012 in Journal of Cell Biology

ABSTRACT

PARP1-mediated poly(ADP-ribosyl)ation of DDB2 prolongs its occupation on UV-damaged chromatin and promotes the recruitment of the chromatin remodeler ALC1.

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