Formation and signaling actions of electrophilic lipids.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Chemical Reviews

• Publication date

  2011-09-20

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/cr200131ePMID 21928855PMCID PMC3294277
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phytochemicals resveratrol and sulforaphane as potential agents for enhancing the anti-tumor activities of conventional cancer therapies.

  2012cited by this paper
• Switching from rosiglitazone: thinking outside the class.

  2011cited by this paper
• Comparative cardiovascular effects of thiazolidinediones: systematic review and meta-analysis of observational studies

  2011cited by this paper
• Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution

  2011cited by this paper
• Nitro‐fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1‐Nrf2 system: a study using green fluorescent protein transgenic zebrafish

  2011cited by this paper
• Redox regulation of the mitochondrial K(ATP) channel in cardioprotection.

  2011cited by this paper
• Risk of Bladder Cancer Among Diabetic Patients Treated With Pioglitazone

  2011cited by this paper
• Bioavailability of Sulforaphane from Two Broccoli Sprout Beverages: Results of a Short-term, Cross-over Clinical Trial in Qidong, China

  2011cited by this paper
• Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

  2011cited by this paper
• Electrophilic Fatty Acids Regulate Matrix Metalloproteinase Activity and Expression*

  2011cited by this paper
• Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent Mechanism*

  2011cited by this paper
• Effect of Bardoxolone Methyl on Kidney Function in Patients with T2D and Stage 3b–4 CKD

  2011cited by this paper
• Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection.

  2011cited by this paper
• Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase.

  2010cited by this paper
• Cysteine-based regulation of the CUL3 adaptor protein Keap1.

  2010cited by this paper
• Discovery and therapeutic potential of drugs that shift energy metabolism from mitochondrial respiration to glycolysis

  2010cited by this paper
• Hsp90 Interaction with INrf2(Keap1) Mediates Stress-induced Nrf2 Activation*

  2010cited by this paper
• Signaling actions of electrophiles: anti-inflammatory therapeutic candidates.

  2010cited by this paper
• Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion.

  2010cited by this paper
• Nrf2: friend or foe for chemoprevention?

  2010cited by this paper
• Nitro-Oleic Acid Inhibits Angiotensin II–Induced Hypertension

  2010cited by this paper
• Nitrated oleic acid up-regulates PPARgamma and attenuates experimental inflammatory bowel disease.

  2010cited by this paper
• A review of the electrophilic reaction chemistry involved in covalent DNA binding

  2010cited by this paper
• Systems Analysis of Protein Modification and Cellular Responses Induced by Electrophile Stress

  2010cited by this paper
• Sulforaphane Activates Heat Shock Response and Enhances Proteasome Activity through Up-regulation of Hsp27*

  2010cited by this paper
• Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation*

  2010cited by this paper
• Electrophilic nitro-fatty acids: anti-inflammatory mediators in the vascular compartment.

  2010cited by this paper
• Site-specific protein adducts of 4-hydroxy-2(E)-nonenal in human THP-1 monocytic cells: protein carbonylation is diminished by ascorbic acid.

  2010cited by this paper
• Nitro–Fatty Acids Reduce Atherosclerosis in Apolipoprotein E–Deficient Mice

  2010cited by this paper
• Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions.

  2010cited by this paper
• Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals

  2010cited by this paper
• Redox Signaling, Alkylation (Carbonylation) of Conserved Cysteines Inactivates Class I Histone Deacetylases 1, 2, and 3 and Antagonizes Their Transcriptional Repressor Function*

  2010cited by this paper
• ANNALS OF THE NEW YORK ACADEMY OF SCIENCES: Redox signaling in inflammation: interactions of endogenous electrophiles and mitochondria in cardiovascular disease

  2010cited by this paper
• Toxicological disruption of signaling homeostasis: tyrosine phosphatases as targets.

  2010cited by this paper
• Nrf2 Induces Interleukin-6 (IL-6) Expression via an Antioxidant Response Element within the IL-6 Promoter*

  2010cited by this paper
• Chemistry and biochemistry of lipid peroxidation products

  2010cited by this paper
• Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids.

  2010cited by this paper
• Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease.

  2010cited by this paper
• Alkylation of the Tumor Suppressor PTEN Activates Akt and β-Catenin Signaling: A Mechanism Linking Inflammation and Oxidative Stress with Cancer

  2010cited by this paper
• Nrf2-ARE stress response mechanism: A control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases

  2010cited by this paper
• 4-Hydroxy-2-nonenal induces calcium overload via the generation of reactive oxygen species in isolated rat cardiac myocytes.

  2009cited by this paper
• Detection and quantification of protein adduction by electrophilic fatty acids: mitochondrial generation of fatty acid nitroalkene derivatives.

  2009cited by this paper
• Substrate Selectivity of 5-Hydroxyeicosanoid Dehydrogenase and Its Inhibition by 5-Hydroxy-Δ6-Long-Chain Fatty Acids

  2009cited by this paper
• Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State

  2009cited by this paper
• Evaluation of an oral carrier system in rats: bioavailability and antioxidant properties of liposome-encapsulated curcumin.

  2009cited by this paper
• Omega-3 fatty acids and heart failure

  2009cited by this paper
• Methods for imaging and detecting modification of proteins by reactive lipid species.

  2009cited by this paper
• Nrf2-dependent and -independent Responses to Nitro-fatty Acids in Human Endothelial Cells

  2009cited by this paper
• Current concepts on the role of inflammation in COPD and lung cancer.

  2009cited by this paper
• 5-Oxo-ETE and the OXE receptor.

  2009cited by this paper
• Chemical genomics of cancer chemopreventive dithiolethiones

  2009cited by this paper
• Mitochondrial nitroalkene formation and mild uncoupling in ischaemic preconditioning: implications for cardioprotection.

  2009cited by this paper
• Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.

  2009cited by this paper
• Critical Methods in Free Radical Biology & Medicine Methods for imaging and detecting modification of proteins by reactive lipid species

  2009cited by this paper
• Transduction of Redox Signaling by Electrophile-Protein Reactions

  2009cited by this paper
• Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids.

  2009cited by this paper
• Convergence of nitric oxide and lipid signaling: anti-inflammatory nitro-fatty acids.

  2009cited by this paper
• Plasma levels of 15d‐PGJ2 are not altered in multiple sclerosis

  2009cited by this paper
• 15-oxo-Eicosatetraenoic Acid, a Metabolite of Macrophage 15-Hydroxyprostaglandin Dehydrogenase That Inhibits Endothelial Cell Proliferation

  2009cited by this paper
• PPARgamma and its ligands: therapeutic implications in cardiovascular disease.

  2009cited by this paper
• Protein cysteine modifications: (2) reactivity specificity and topics of medicinal chemistry and protein engineering.

  2009cited by this paper
• HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins*

  2009cited by this paper
• Global Analysis of Protein Damage by the Lipid Electrophile 4-Hydroxy-2-nonenal*S⃞

  2009cited by this paper
• Nitro-fatty Acid Metabolome: Saturation, Desaturation, β-Oxidation, and Protein Adduction*

  2009cited by this paper
• Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by nitroalkene fatty acids: importance of nitration position and degree of unsaturation.

  2009cited by this paper
• Structural basis for the activation of PPARγ by oxidized fatty acids

  2008cited by this paper
• Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates.

  2008cited by this paper
• NF-E2-Related Factor 2 Inhibits Lipid Accumulation and Oxidative Stress in Mice Fed a High-Fat Diet

  2008cited by this paper
• Molecular recognition of nitro-fatty acids by PPAR gamma

  2008cited by this paper
• Anti-inflammatory and proresolving lipid mediators.

  2008cited by this paper
• Molecular recognition of nitrated fatty acids by PPARγ

  2008cited by this paper
• Accumulation of 15-deoxy-delta(12,14)-prostaglandin J2 adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction.

  2008cited by this paper
• Mitochondrial protein targets of thiol-reactive electrophiles.

  2008cited by this paper
• In vitro and in silico characterization of peroxiredoxin 6 modified by 4-hydroxynonenal and 4-oxononenal.

  2008cited by this paper
• Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling.

  2008cited by this paper
• Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity.

  2008cited by this paper
• Insights into PPARγ from structures with endogenous and covalently bound ligands

  2008cited by this paper
• Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A3/J3-Isoprostanes) in Vivo from Eicosapentaenoic Acid*

  2008cited by this paper
• Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action.

  2008cited by this paper
• Fat and beyond: the diverse biology of PPARgamma.

  2008cited by this paper
• Nitro-fatty Acid Formation and Signaling*

  2008cited by this paper
• Molecular Mechanisms of the Conjugated α,β-Unsaturated Carbonyl Derivatives: Relevance to Neurotoxicity and Neurodegenerative Diseases

  2008cited by this paper
• Detection of Catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE

  2008cited by this paper
• Dual roles of Nrf2 in cancer.

  2008cited by this paper
• Structural basis for the activation of PPARgamma by oxidized fatty acids.

  2008cited by this paper
• Molecular mechanisms of the conjugated alpha,beta-unsaturated carbonyl derivatives: relevance to neurotoxicity and neurodegenerative diseases.

  2008cited by this paper
• Human Neutrophils Convert the Sebum-derived Polyunsaturated Fatty Acid Sebaleic Acid to a Potent Granulocyte Chemoattractant*

  2008cited by this paper
• Structural Basis for the Activation of Pparg by Oxidised Fatty Acids

  2008cited by this paper
• Reversibility of covalent electrophile-protein adducts and chemical toxicity.

  2008cited by this paper
• Insulin sensitivity: modulation by nutrients and inflammation.

  2008cited by this paper
• Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease.

  2008cited by this paper
• Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease

  2008cited by this paper
• Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis.

  2008cited by this paper
• Abstract 1704: Nitro-Fatty Acid Inhibition of Neointima Formation after Endoluminal Vessel Injury

  2008cited by this paper
• Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.

  2008cited by this paper
• Identification of Proteins Adducted by Lipid Peroxidation Products in Plasma and Modifications of Apolipoprotein A1 with a Novel Biotinylated Phospholipid Probe

  2008cited by this paper
• The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds

  2008cited by this paper
• Electrophilic Cyclopentenone Neuroprostanes Are Anti-inflammatory Mediators Formed from the Peroxidation of the ω-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid*

  2008cited by this paper
• Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives.

  2008cited by this paper
• Food Omega-3 Fatty Acid Intake of Individuals (Total, Linolenic Acid, Long-Chain) and Their Blood Pressure: INTERMAP Study

  2007cited by this paper

• Integrated GC-MS/MS Metabolomics in Cardiovascular Disease: Targeted Nitro-Oleic Acid Quantification Meets Untargeted Profiling.

  2026cites this paper
• NCBP1 stress signaling drives alternative S6K1 splicing inhibiting translation.

  2026cites this paper
• Plant-specific tau class glutathione transferases safeguard against lipid oxidation stress through dual detoxification of lipid peroxides and reactive carbonyl species

  2025cites this paper
• Chemoproteomic analysis reveals RECQL4 as a mediator of nitroalkene-dependent double-strand break repair inhibition in cancer.

  2025cites this paper
• Nitro‐fatty acids‐mediated nitroalkylation modulates fine‐tuning catalase antioxidant function during salinity stress in plants

  2025cites this paper
• Chlorogenic acid and intestinal health: mechanistic insights and therapeutic applications.

  2025cites this paper
• Formation of protein-derived electrophiles in ribonuclease A by biologically relevant oxidants

  2025cites this paper
• Nitro-Fatty Acid Signaling and Intracellular Biodistribution in Plants.

  2025cites this paper
• Discovery of potential inhibitors from Linum grandiflorum Desf. against HIV-1 RT, in vitro, molecular docking and molecular dynamics simulation supported study

  2025cites this paper
• Nitro-fatty acids modulate germination onset through S-nitrosothiol metabolism

  2025cites this paper
• Single-step assay of lipid derived electrophiles by reagent release micro capillary immobilizing fluorescent probe

  2025cites this paper
• Fluorescent probe to quantify lipid-derived electrophiles in edible oils.

  2024cites this paper
• Reactions of lipid hydroperoxides and how they may contribute to ferroptosis sensitivity.

  2024cites this paper
• Protein nitration in the artery wall: a contributor to cardiovascular disease?

  2024cites this paper
• Chemistry of nitrogen dioxide and its biological implicatios

  2024cites this paper
• Lipid-derived electrophiles inhibit the function of membrane channels during ferroptosis

  2024cites this paper
• Age-Dependent Changes in Nrf2/Keap1 and Target Antioxidant Protein Expression Correlate to Lipoxidative Adducts, and Are Modulated by Dietary N-3 LCPUFA in the Hippocampus of Mice

  2024cites this paper
• Highly selective cytokine induction of nitrated lipid-modified α-GalCer derivatives demonstrating high binding affinity to the lipid antigen presenting molecule CD1d.

  2024cites this paper
• Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling

  2024cites this paper
• Chronic inorganic nitrate supplementation does not improve metabolic health and worsens disease progression in mice with diet-induced obesity

  2024cites this paper
• Adipocyte-specific Nrf2 Deletion Negates Nitro-Oleic Acid Benefits on Glucose Tolerance in Diet-Induced Obesity.

  2024cites this paper
• The Complex Roles of Redox and Antioxidant Biology in Cancer.

  2024cites this paper
• The Octadecanoids: Synthesis and Bioactivity of 18-Carbon Oxygenated Fatty Acids in Mammals, Bacteria, and Fungi

  2024cites this paper
• Metabolome regulation and restoration mechanism of different varieties of rice (Oryza sativa L.) after lindane stress.

  2024cites this paper
• Electrophilic metabolites targeting the KEAP1/NRF2 partnership.

  2024cites this paper
• The Peroxidation of Lipids, Cellular Senescence and Aging

  2024cites this paper
• PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury

  2024cites this paper
• Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling

  2024cites this paper
• Climbing into their Skin to Understand Contextual Protein–Protein Associations and Localizations: Functional Investigations in Transgenic Live Model Organisms

  2024cites this paper
• Metabolic pathways, genomic alterations, and post-translational modifications in pulmonary hypertension and cancer as therapeutic targets and biomarkers

  2024cites this paper
• Functions of nitric oxide-mediated post-translational modifications under abiotic stress

  2023cites this paper
• How do different lipid peroxidation mechanisms contribute to ferroptosis?

  2023cites this paper
• Structural Insights into Electrophiles and Electrophilic Metabolites Sensing and Signaling: The Missing Information

  2023cites this paper
• Lipid Peroxidation and Antioxidant Protection

  2023cites this paper
• A metabolic perspective on nitric oxide function in melanoma.

  2023cites this paper
• Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis

  2023cites this paper
• Metabolic Reprogramming, Genomic Alterations, and Post-Translational Modifications in Pulmonary Hypertension and Cancer: Implications for Biomarkers and Therapeutic Targeting

  2023cites this paper
• Effect of nitro-conjugated linoleic acid on the inflammatory response of murine macrophages activated with lipopolysaccharide derived from Prevotella intermedia

  2023cites this paper
• MRP1 inhibition by lipid-derived electrophiles during ferroptosis illustrates a role for protein alkylation in ferroptotic cell death

  2023cites this paper
• Covalent ligands of nuclear receptors.

  2023cites this paper
• Nitro-fatty acids as novel Virgin olive oil quality markers

  2023cites this paper
• Digestive interaction between dietary nitrite and dairy products generates novel nitrated linolenic acid products.

  2023cites this paper
• Z-REX uncovers a bifurcation in function of Keap1 paralogs

  2022influential citation
• Targeting NRF2-KEAP1 axis by Omega-3 fatty acids and their derivatives: Emerging opportunities against aging and diseases.

  2022cites this paper
• Nanoparticles encapsulating sesame seeds (Sesamum indicum) oil: Physicochemical, antioxidant and enzymatic inhibition properties

  2022cites this paper
• Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish

  2022cites this paper
• The isothiocyanate sulforaphane induces respiratory burst oxidase homologue D‐dependent reactive oxygen species production and regulates expression of stress response genes

  2022cites this paper
• Redox Regulation of Soluble Epoxide Hydrolase—Implications for Cardiovascular Health and Disease

  2022cites this paper
• Nitrated Fatty-Acids Distribution in Storage Biomolecules during Arabidopsis thaliana Development

  2022cites this paper
• Identification of structural features of selected flavonoids responsible for neuroprotection using a Drosophila model of Parkinson’s disease

  2022cites this paper
• Involvement of Fatty Acids and Their Metabolites in the Development of Inflammation in Atherosclerosis

  2022cites this paper
• Immunomodulatory actions of a kynurenine-derived endogenous electrophile

  2022cites this paper
• Nitrooleic acid inhibits macrophage activation induced by lipopolysaccharide from Prevotella intermedia.

  2022cites this paper
• Function-guided proximity mapping unveils electrophilic-metabolite sensing by proteins not present in their canonical locales

  2022cites this paper
• Live-cell imaging reveals impaired detoxification of lipid-derived electrophiles is a hallmark of ferroptosis

  2022cites this paper
• Detection of Nitro-Conjugated Linoleic Acid and Nitro-oleic Acid in Virgin Olive Oil under Gastric Conditions: Relationship to Cultivar, Fruit Ripening, and Polyphenol Content

  2022cites this paper
• Brain Damage and Patterns of Neurovascular Disorder after Ionizing Irradiation. Complications in Radiotherapy and Radiation Combined Injury

  2021cites this paper
• Electrophilic nitro-fatty acids suppress psoriasiform dermatitis: STAT3 inhibition as a contributory mechanism

  2021cites this paper
• DHA and Its Elaborated Modulation of Antioxidant Defenses of the Brain: Implications in Aging and AD Neurodegeneration

  2021influential citation
• Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO2) and nitroalkene (RNO2) substituents

  2021cites this paper
• Olive oil-derived nitro-fatty acids: protection of mitochondrial function in non-alcoholic fatty liver disease.

  2021cites this paper
• Regulation of redox signaling by reactive sulfur species

  2021cites this paper
• Comparative Cytotoxicity Study of PM2.5 and TSP Collected from Urban Areas

  2021cites this paper
• Protein Lipoxidation: Basic Concepts and Emerging Roles

  2021cites this paper
• Activity modulation of anti‐sigma factor via cysteine alkylation in Actinobacteria

  2021cites this paper
• Oxidative Modification of Proteins: From Damage to Catalysis, Signaling, and Beyond

  2021cites this paper
• Polyvinyl Alcohol Carbazate as a Polymer-Based Antitumoral Agent

  2021cites this paper
• Nitro Fatty Acids (NO2-FAs): An Emerging Class of Bioactive Fatty Acids

  2021cites this paper
• Insights into the Pathogenesis of Neurodegenerative Diseases: Focus on Mitochondrial Dysfunction and Oxidative Stress

  2021cites this paper
• Drug discovery from natural products - Old problems and novel solutions for the treatment of neurodegenerative diseases.

  2021cites this paper
• Nitro-fatty acids: electrophilic signaling molecules in plant physiology

  2021cites this paper
• Inhibiting homologous recombination by targeting RAD51 protein.

  2021cites this paper
• Aldehydes’ Sources, Toxicity, Environmental Analysis, and Control in Food

  2021cites this paper
• Fatty acid nitroalkene reversal of established lung fibrosis

  2021cites this paper
• A Not-So-Ancient Grease History: Click Chemistry and Protein Lipid Modifications.

  2021cites this paper
• Lipid Peroxide-Derived Reactive Carbonyl Species as Mediators of Oxidative Stress and Signaling

  2021cites this paper
• Role of nitric oxide–dependent posttranslational modifications of proteins under abiotic stress

  2020cites this paper
• Reactive Sterol Electrophiles: Mechanisms of Formation and Reactions with Proteins and Amino Acid Nucleophiles

  2020cites this paper
• Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages

  2020cites this paper
• Reaction targets of antioxidants in azo-initiator or lipid hydroperoxide induced lipid peroxidation

  2020cites this paper
• Method for Structural Determination of Lipid-derived Radicals.

  2020cites this paper
• Application of the hard and soft, acids and bases (HSAB) theory as a method to predict cumulative neurotoxicity.

  2020cites this paper
• Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys

  2020cites this paper
• Persulfide-Dependent Regulation of Electrophilic Redox Signaling in Neural Cells

  2020cites this paper
• The mRNA-binding protein HuR is a kinetically-privileged electrophile sensor

  2020cites this paper
• A novel nitroalkene vitamin E analogue inhibits the NLRP3 inflammasome and protects against inflammation and glucose intolerance triggered by obesity

  2020cites this paper
• Connecting the "Dots": From Free Radical Lipid Autoxidation to Cell Pathology and Disease.

  2020cites this paper
• Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro

  2020cites this paper
• Nrf2 Activation and Its Coordination with the Protective Defense Systems in Response to Electrophilic Stress

  2020cites this paper
• Electrophile Modulation of Inflammation: A Two-Hit Approach

  2020influential citation
• Nontargeted Identification of Plasma Proteins O-, N-, and S-Transmethylated by O-Methyl Organophosphates.

  2020cites this paper
• Nitro-fatty acids as activators of hSIRT6 deacetylase activity

  2020cites this paper
• Mass spectrometry-based study defines the human urine nitrolipidome.

  2020cites this paper
• Electrophilic characteristics and aqueous behavior of fatty acid nitroalkenes

  2020cites this paper
• Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals

  2020cites this paper
• Role of electrophilic nitrated fatty acids during development and response to abiotic stress processes in plants.

  2020cites this paper
• Untargeted Approach for Revealing Electrophilic Metabolites.

  2020cites this paper
• Primary saturation of α,β-unsaturated carbonyl containing fatty acids does not abolish electrophilicity

  2020cites this paper
• Plant Unsaturated Fatty Acids: Multiple Roles in Stress Response

  2020cites this paper
• Modulatory role of dietary polyunsaturated fatty acids in Nrf2-mediated redox homeostasis.

  2020cites this paper