The role of calcium in the response of cardiac muscle to stretch.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Progress in Biophysics and Molecular Biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0079-6107(98)00037-6PMID 10070212
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Modulation of ions channels and membrane receptors activities by mechanical interventions in cardiomyocytes: possible mechanisms for mechanosensitivity.

  1999cited by this paper
• Stretch-induced changes in heart rate and rhythm: clinical observations, experiments and mathematical models.

  1999cited by this paper
• Mechanosensitivity as an integrative system in heart: an audit.

  1999cited by this paper
• Effect of ventricular stretch on contractile strength, calcium transient, and cAMP in intact canine hearts.

  1998cited by this paper
• Changes in force and cytosolic Ca2+ concentration after length changes in isolated rat ventricular trabeculae

  1998cited by this paper
• Length dependence of calcium- and force-transients in normal and failing human myocardium.

  1998cited by this paper
• Cellular mechanisms of cardiac mechano-electric feedback in a mathematical model.

  1998cited by this paper
• Swelling-induced decrease in spontaneous pacemaker activity of rabbit isolated sino-atrial node cells.

  1998cited by this paper
• Shortening versus isometric contractions in isolated human failing and non-failing left ventricular myocardium: dependency of external work and force on muscle length, heart rate and inotropic stimulation.

  1998cited by this paper
• Effect of ventricular stretch on contractile strength, calcium transient, and cAMP in intact canine hearts.

  1998cited by this paper
• Mechanisms of length history-dependent tension in an ionic model of the cardiac myocyte.

  1998cited by this paper
• The cardiac troponin C isoform and the length dependence of Ca2+ sensitivity of tension in myocardium.

  1997cited by this paper
• Intracellular Ca2+ signalling in secretory cells.

  1997cited by this paper
• The cellular and molecular response of cardiac myocytes to mechanical stress.

  1997cited by this paper
• Stretch-activated ion channels in the heart.

  1997cited by this paper
• Basic determinants of myocardial hypertrophy: a review of molecular mechanisms.

  1997cited by this paper
• Resting tension participates in the modulation of active tension in isolated guinea pig ventricular myocytes.

  1997cited by this paper
• Effect of stretch on calcium channel currents recorded from the antral circular myocytes of guinea-pig stomach

  1996cited by this paper
• Existence of the Frank-Starling mechanism in the failing human heart. Investigations on the organ, tissue, and sarcomere levels.

  1996cited by this paper
• Length‐dependent mechanisms in single cardiac cells

  1996cited by this paper
• Roles of Cl- channels and Ca2+ mobilization in stretch-induced increase of SA node pacemaker activity.

  1996cited by this paper
• Heart failure and Starling's Law of the heart.

  1996cited by this paper
• Changes in [Ca2+]i, [Na+]i and Ca2+ current in isolated rat ventricular myocytes following an increase in cell length.

  1996cited by this paper
• A hierarchical concept of cellular and subcellular Ca(2+)-signalling.

  1996cited by this paper
• Mechano-electrical feedback in ventricular myocardium.

  1996cited by this paper
• Passive load and angiotensin II evoke differential responses of gene expression and protein synthesis in cardiac myocytes.

  1996cited by this paper
• Stretch-induced increase in atrial natriuretic peptide secretion is blocked by thapsigargin.

  1996cited by this paper
• A list of vertebrate cardiac ionic currents nomenclature, properties, function and cloned equivalents.

  1996cited by this paper
• Mechanoelectric feedback (transduction) in heart: concepts and implications.

  1996cited by this paper
• Heart failure and Starling's Law of the heart.

  1996cited by this paper
• Mechano-electric feedback in the human heart.

  1996cited by this paper
• Cell swelling and ion transport pathways in cardiac myocytes.

  1996cited by this paper
• Mechanosensitive connective tissue: potential influence on heart rhythm.

  1996cited by this paper
• Mechanoelectric feedback in the atrium of the isolated guinea-pig heart.

  1996cited by this paper
• The role of Na-Ca exchange current in the cardiac action potential.

  1996cited by this paper
• Mechanically Activated Currents in Chick Heart Cells

  1996cited by this paper
• Calcium and mechanically induced potentials in fibroblasts of rat atrium.

  1996cited by this paper
• Role of calcium in stretch-induced release and mRNA synthesis of natriuretic peptides in isolated rat atrium

  1996cited by this paper
• A possible mechanism for large stretch-induced increase in [Ca2+]i in isolated guinea-pig ventricular myocytes.

  1996cited by this paper
• Sarcomere length versus interfilament spacing as determinants of cardiac myofilament Ca2+ sensitivity and Ca2+ binding.

  1996cited by this paper
• Enhancement of the L-type Ca2+ current by mechanical stimulation in single rabbit cardiac myocytes.

  1996cited by this paper
• The effects of mechanical loading and changes of length on single guinea‐pig ventricular myocytes.

  1995cited by this paper
• Mechanical Modulation of the Ca2+ Regulatory Protein Complex in Cardiac Muscle

  1995cited by this paper
• Calcium regulation of gene expression.

  1995cited by this paper
• Effect of stretch on contraction and the Ca2+ transient in ferret ventricular muscles during hypoxia and acidosis.

  1995cited by this paper
• Angiotensin II and Other Hypertrophic Stimuli Mediated by G Protein–Coupled Receptors Activate Tyrosine Kinase, Mitogen-Activated Protein Kinase, and 90-kD S6 Kinase in Cardiac Myocytes The Critical Role of Ca2+-Dependent Signaling

  1995cited by this paper
• Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD S6 kinase in cardiac myocytes. The critical role of Ca(2+)-dependent signaling.

  1995cited by this paper
• Calcium- and sodium-dependent modulation of stretch-induced arrhythmias in isolated canine ventricles.

  1995cited by this paper
• Osmotic compression of skinned cardiac and skeletal muscle bundles: effects on force generation, Ca2+ sensitivity and Ca2+ binding.

  1995cited by this paper
• Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments.

  1995cited by this paper
• Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy.

  1995cited by this paper
• Molecular mechanism of cardiac cellular hypertrophy by mechanical stress.

  1995cited by this paper
• Calcium-dependent regulation of protein synthesis.

  1995cited by this paper
• Length dependence of Ca2+ sensitivity of tension in mouse cardiac myocytes expressing skeletal troponin C.

  1995cited by this paper
• Tension‐dependent changes of the intracellular Ca2+ transients in ferret ventricular muscles.

  1995cited by this paper
• Osmotic compression of single cardiac myocytes eliminates the reduction in Ca2+ sensitivity of tension at short sarcomere length.

  1995cited by this paper
• Sarcoplasmic reticulum in cardiac length-dependent activation in rabbits.

  1995cited by this paper
• Effect of ryanodine on the initiation and perpetuation of stretch-induced arrhythmias in isolated canine ventricle.

  1994cited by this paper
• Effect of ryanodine on atrial natriuretic peptide secretion by contracting and quiescent rat atrium

  1994cited by this paper
• Block of stretch‐activated atrial natriuretic peptide secretion by gadolinium in isolated rat atrium.

  1994cited by this paper
• The failing human heart is unable to use the Frank-Starling mechanism.

  1994cited by this paper
• Lack of importance in humans of the slow component of the response of force to an increase in cardiac muscle length.

  1994cited by this paper
• Streptomycin reverses a large stretch induced increases in [Ca2+]i in isolated guinea pig ventricular myocytes.

  1994cited by this paper
• The cellular actions of digitalis glycosides on the heart.

  1994cited by this paper
• A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes.

  1994cited by this paper
• Chapter 11 Chloride Ion Channels in Mammalian Heart Cells

  1994cited by this paper
• Stretching releases Ca2+ from intracellular storage sites in canine cerebral arteries.

  1994cited by this paper
• Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes.

  1993cited by this paper
• Control of cardiac gene expression by mechanical stress.

  1993cited by this paper
• Novel cation-selective mechanosensitive ion channel in the atrial cell membrane.

  1993cited by this paper
• The effects of increasing cell length on auxotonic contractions; membrane potential and intracellular calcium transients in single guinea‐pig ventricular myocytes

  1993cited by this paper
• Control of the calcium pump of cardiac sarcoplasmic reticulum. A specific role for the pentameric structure of phospholamban?

  1993cited by this paper
• Mechanisms of volume-induced increase in left ventricular contractility.

  1993cited by this paper
• Calcium channel currents recorded from isolated myocytes of rat basilar artery are stretch sensitive.

  1993cited by this paper
• Stretch-activated ion channels in tissue-cultured chick heart.

  1993cited by this paper
• Alterations in intracellular calcium and tension of activated ferret papillary muscle in response to step length changes.

  1993cited by this paper
• Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism.

  1993cited by this paper
• Cardiac pacemaking in the sinoatrial node.

  1993cited by this paper
• Stretch-induced inositol trisphosphate and tetrakisphosphate production in rat cardiomyocytes.

  1993cited by this paper
• The influence of calcium on ANF release in the isolated rat atrium.

  1992cited by this paper
• Effects of mechanical stretch on membrane currents of single ventricular myocytes of guinea-pig heart.

  1992cited by this paper
• Isoprenaline reverses the slow force responses to a length change in isolated rabbit papillary muscle

  1992cited by this paper
• Stretch‐activated anion currents of rabbit cardiac myocytes.

  1992cited by this paper
• Calcium imaging of mechanically induced fluxes in tissue-cultured chick heart: role of stretch-activated ion channels.

  1992cited by this paper
• Atrial natriuretic peptide: synthesis, release, and metabolism.

  1992cited by this paper
• Myocardial stretch alters twitch characteristics and Ca2+ loading of sarcoplasmic reticulum in rat ventricular muscle.

  1992cited by this paper
• Afterdepolarizations and triggered activity: distinction from automaticity as an arrhythmogenic mechanism.

  1992cited by this paper
• Stretch-activated channels in heart cells: relevance to cardiac hypertrophy.

  1991cited by this paper
• Dose-dependent inhibition of stretch-induced arrhythmias by gadolinium in isolated canine ventricles. Evidence for a unique mode of antiarrhythmic action.

  1991cited by this paper
• Function follows form: generation of intracellular signals by cell deformation

  1991cited by this paper
• Substitution of cardiac troponin C into rabbit muscle does not alter the length dependence of Ca2+ sensitivity of tension.

  1991cited by this paper
• Excitation-Contraction Coupling and Cardiac Contractile Force

  1991cited by this paper
• Effect of external Ca2+ concentration on stretch-augmented natriuretic peptide secretion by rat atria.

  1991cited by this paper
• The role of troponin C in the length dependence of Ca(2+)‐sensitive force of mammalian skeletal and cardiac muscles.

  1991cited by this paper
• Stretch‐induced increase of resting intracellular calcium concentration in single guinea‐pig ventricular myocytes

  1991cited by this paper
• Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum.

  1990cited by this paper
• Basal and stretch-augmented natriuretic peptide secretion by quiescent rat atria.

  1990cited by this paper
• Calcium-dependent regulation of protein synthesis in intact mammalian cells.

  1990cited by this paper
• Effect of higher aortic pressure on ribosome formation and cAMP content in rat heart.

  1989cited by this paper
• Effect of manipulations of Ca2+ environment on atrial natriuretic factor release.

  1989cited by this paper

• The pesticide fungicide difenoconazole modulates the biophysical properties of sodium channel Nav1.5.

  2025cites this paper
• Recombinant–Chemosynthetic Biosensors for Probing Cell Surface Signaling of Red Blood Cells and Other Cells

  2025cites this paper
• Transcriptomic analysis on cucumber tendril reveals GLRs play important roles in thigmotropism and thigmomorphogenesis

  2023cites this paper
• The mechano-electric feedback mediates the dual effect of stretch in mouse sinoatrial tissue

  2023cites this paper
• A detailed mathematical model of the human atrial cardiomyocyte: integration of electrophysiology and cardiomechanics

  2023cites this paper
• Machine learning-based classification of cardiac relaxation impairment using sarcomere length and intracellular calcium transients

  2023cites this paper
• The in vivo study of cardiac mechano-electric and mechano-mechanical coupling during heart development in zebrafish

  2023cites this paper
• Effects of Sarcolemmal Background Ca2+ Entry and Sarcoplasmic Ca2+ Leak Currents on Electrophysiology and Ca2+ Transients in Human Ventricular Cardiomyocytes: A Computational Comparison

  2022cites this paper
• Retrospective Evaluation of the Cases Presenting to the Pediatric Intensive Care Unit with Cardiogenic Shock in Terms of Etiology, Treatment and Long-Term Prognosis

  2022cites this paper
• Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway

  2021cites this paper
• Mechano-arrhythmogenicity is enhanced during late repolarisation in ischemia and driven by a TRPA1-, calcium-, and reactive oxygen species-dependent mechanism

  2021cites this paper
• X-ROS Signaling Depends on Length-Dependent Calcium Buffering by Troponin

  2021cites this paper
• Cardiac Mechano-Electric Coupling: Acute Effects of Mechanical Stimulation on Heart Rate and Rhythm.

  2020cites this paper
• Influence of Crocetin, a Natural Carotenoid Dicarboxylic Acid in Saffron, on L-Type Ca2+ Current, Intracellular Ca2+ Handling and Contraction of Isolated Rat Cardiomyocytes.

  2020cites this paper
• Non-optogenetic approaches for leadless cardiac pacing: mechanically induced excitation for extracorporeal control of cardiac rhythm

  2020cites this paper
• Cardioprotective effects of glycyrrhizic acid involve inhibition of calcium influx via L-type calcium channels and myocardial contraction in rats

  2019cites this paper
• Mechano-calcium and mechano-electric feedbacks in the human cardiomyocyte analyzed in a mathematical model

  2019cites this paper
• New Mathematical Model of Electromechanical Coupling in Rat Cardiomyocytes

  2018cites this paper
• Understanding the Loss of Capture During Mechanical Pacing of the Heart

  2018cites this paper
• Stimulateur cardiaque biologique : effets de la répartition spatiale des cardiomyocytes avec activité spontanée et de l'étirement uniaxial

  2018cites this paper
• Mechano-electrical feedback in the clinical setting: Current perspectives.

  2017cites this paper
• In-silico investigations of the functional impact of KCNA5 mutations on atrial mechanical dynamics.

  2017cites this paper
• Biophysical modelling of functional impacts of potassium channel mutations on human atrial and ventricular dynamics

  2017cites this paper
• The effect of hypothermia and rewarming on cardiac electrophysiology and mechanical function

  2017cites this paper
• Rabbit models of cardiac mechano-electric and mechano-mechanical coupling

  2016cites this paper
• The potential of ultrasound in cardiac pacing and rhythm modulation

  2016cites this paper
• Altered Calcium Handling and Ventricular Arrhythmias in Acute Ischemia

  2016cites this paper
• Comparing maximum rate and sustainability of pacing by mechanical vs. electrical stimulation in the Langendorff-perfused rabbit heart

  2016cites this paper
• The NO stimulator, Catestatin, improves the Frank-Starling response in normotensive and hypertensive rat hearts.

  2015cites this paper
• Stretch-induced increase in cardiac contractility is independent of myocyte Ca2+ while block of stretch channels by streptomycin improves contractility after ischemic stunning

  2015cites this paper
• Touch Induced Plant Defense Response

  2015cites this paper
• Arrhythmogenic effects by local left ventricular stretch: effects of flecainide and streptomycin

  2014cites this paper
• Effect of cardiac ventricular mechanical contraction on the characteristics of the ECG: A simulation study

  2013cites this paper
• Ionic bases for electrical remodeling of the canine cardiac ventricle.

  2013cites this paper
• The importance of non-uniformities in mechano-electric coupling for ventricular arrhythmias

  2013cites this paper
• Stretch Current‐Induced Abnormal Impulses in CaMKIIδ Knockout Mouse Ventricular Myocytes

  2013cites this paper
• In silico investigation of the short QT syndrome, using human ventricle models incorporating electromechanical coupling

  2013cites this paper
• Correlation between T-Wave Alternans and Cardiac Volume Status via Intrathoracic Impedance Measurements

  2012cites this paper
• Stretch of Contracting Cardiac Muscle Abruptly Decreases the Rate of Phosphate Release at High and Low Calcium

  2012cites this paper
• Contractile properties of the axolotl ventricle at 17 and 21 °C

  2012cites this paper
• Passive Cardiac Properties and Titin Expression in Dilated Cardiomyopathy

  2012cites this paper
• Chapter 14 – Cardiovascular Mechanotransduction

  2012cites this paper
• Computer modeling and signal analysis of cardiovascular physiology

  2012cites this paper
• Mechano-sensitivity of cardiac pacemaker function: Pathophysiological relevance, experimental implications, and conceptual integration with other mechanisms of rhythmicity

  2012cites this paper
• A microscope configuration for nanometer 3-D movement monitoring accuracy.

  2011cites this paper
• Mechanical Modulation of a Reentrant Arrhythmia: The Atrial Flutter Case

  2010cites this paper
• Exercise training-induced enhancement in myocardial mechanics is lost after 2 weeks of detraining in rats

  2010cites this paper
• Enhanced length-dependent Ca2+ activation in fish cardiomyocytes permits a large operating range of sarcomere lengths.

  2010cites this paper
• The role of nitric oxide and reactive oxygen species in the positive inotropic response to mechanical stretch in the mammalian myocardium

  2009cites this paper
• The role of Ca(2+) signaling in the coordination of mitochondrial ATP production with cardiac work.

  2009influential citation
• Axial Stretch of Rat Single Ventricular Cardiomyocytes Causes an Acute and Transient Increase in Ca2+ Spark Rate

  2009cites this paper
• Mechanisms of conduction slowing during myocardial stretch by ventricular volume loading in the rabbit.

  2008cites this paper
• Thigmomorphogenesis: a complex plant response to mechano-stimulation.

  2008cites this paper
• A Model for Mechano-Electrical Feedback Effects on Atrial Flutter Interval Variability

  2008cites this paper
• Stretch-activated non-selective cation channel: a causal link between mechanical stretch and atrial natriuretic peptide secretion.

  2008cites this paper
• Inhomogeneity in the response to mechanical stimulation: cardiac muscle function and gene expression.

  2008cites this paper
• Life and mechanosensitivity.

  2008cites this paper
• Axial stretch enhances sarcoplasmic reticulum Ca2+ leak and cellular Ca2+ reuptake in guinea pig ventricular myocytes: experiments and models.

  2008cites this paper
• Cardiac electrophysiology and mechanoelectric feedback : modeling and simulation

  2008cites this paper
• Efeitos do exercício crônico sobre os miócitos cardíacos: Uma revisão das adaptações mecânicas

  2008cites this paper
• Experimental Methods of Studying Mechanosensitive Channels and Possible Errors in Data Interpretation

  2008cites this paper
• The Role of the Sarcomere and Cytoskeleton in Cardiac Mechanotransduction

  2007cites this paper
• Mechanoelectric feedback leads to conduction slowing and block in acutely dilated atria: a modeling study of cardiac electromechanics.

  2007cites this paper
• The effect of streptomycin on stretch-induced electrophysiological changes of isolated acute myocardial infarcted hearts in rats.

  2007cites this paper
• The effect of streptomycin on stretch-induced electrophysiological changes of isolated acute myocardial infarcted hearts in rats {

  2007cites this paper
• Modulation of local Ca2+ release sites by rapid fluid puffing in rat atrial myocytes.

  2007cites this paper
• Mechanoelectric Transduction/Feedback: Physiology and Pathophysiology

  2007cites this paper
• Strain-related regional alterations of calcium-handling proteins in myocardial remodeling.

  2006cites this paper
• Mechanosensitive channels: therapeutic targets in the myocardium?

  2006cites this paper
• Mechanosensitive‐Mediated Interaction, Integration, and Cardiac Control

  2006cites this paper
• Ventricular Remodeling In Ischemic Cardiomyopathy

  2006cites this paper
• Touch-Responsive Behaviors and Gene Expression in Plants

  2006cites this paper
• Stretch induced accumulation of total Ca and Na in cytosol and nucleus: a comparison between cardiac trabeculae and isolated myocytes.

  2006cites this paper
• Mechanosensitivity in Cells and Tissues

  2005cites this paper
• Altered hetero‐ and homeometric autoregulation in the terminally failing human heart

  2005cites this paper
• Efeitos do exercício crônico sobre os miócitos cardíacos: uma revisão das adaptações mecânicas Effects of chronic exercise on cardiac myocytes: a review about mechanical adaptations

  2004cites this paper
• Mechanotransduction in Cardiac Myocytes

  2004cites this paper
• Chapter 27 – Mechanoelectric Transduction/Feedback: Prevalence and Pathophysiology

  2004cites this paper
• Interaction of mitochondria and ATPases in oxidative muscle cells in normal and pathological conditions

  2004cites this paper
• Induced automaticity in isolated rat atrial cells by incorporation of a stretch-activated conductance

  2004influential citation
• In touch: plant responses to mechanical stimuli.

  2004cites this paper
• Fluorescence polarization: a novel indicator of cardiomyocyte contraction.

  2003cites this paper
• Taurine-depleted heart and afterload pressure.

  2003cites this paper
• Do stretch-induced changes in intracellular calcium modify the electrical activity of cardiac muscle?

  2003cites this paper
• Reverse Molecular Remodeling of the Failing Human Heart Following Support with a Left Ventricular Assist Device

  2003cites this paper
• Passive ventricular constraint.

  2003cites this paper
• Ion selectivity of stretch-activated cation currents in mouse ventricular myocytes

  2003cites this paper
• Stunning and myocardial contractile autoregulation studied on the isolated isovolumic blood-perfused dog heart.

  2003cites this paper
• Mechanical Interaction of Heterogeneous Cardiac Muscle Segments in silico: Effects on CA2+ Handling and Action Potential

  2003cites this paper
• Beat-to-beat modulation of right and left ventricular positive dP/dt by afterload Implications for the evaluation of inotropy

  2003cites this paper
• Mechano-electric feedback and arrhythmias.

  2003cites this paper
• Streptomycin and intracellular calcium modulate the response of single guinea‐pig ventricular myocytes to axial stretch

  2003cites this paper
• Biomechanically Induced Gene iex-1 Inhibits Vascular Smooth Muscle Cell Proliferation and Neointima Formation

  2003cites this paper
• Mechano-electric feedback and atrial fibrillation.

  2003cites this paper
• Nitric-oxide-mediated regulation of cardiac contractility and stretch responses.

  2003cites this paper
• Characterization of stretch-activated ion currents in isolated atrial myocytes from human hearts

  2003cites this paper
• Increments in the concentrations of sodium and calcium in cell compartments of stretched mouse ventricular myocytes.

  2003cites this paper
• Role of Integrins in Endothelial Mechanosensing of Shear Stress Dance Band on the Titanic: Biomechanical Signaling in Cardiac Hypertrophy Spatial Microstimuli in Endothelial Mechanosignaling Dynamic Regulation of Connexins in Connection With Mechanosignaling

  2002cites this paper
• The Frank -Starling Relationship: Cellular and Molecular Mechanisms

  2002cites this paper
• Length dependence of cardiac myofilament Ca(2+) sensitivity in the presence of substitute nucleoside triphosphates.

  2002cites this paper