Inhibition of plasmin activity by alpha-2-macroglobulin.

No abstract is available for this paper.

• Publication year

  1967

• Venue

  Clinica chimica acta; international journal of clinical chemistry

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  PMID 4166401
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Alpha-2-anti-trypsin activity and different trypsin substrates.

  1966cited by this paper
• Dissociation of Esterolytic and Clotting Activities of Thrombin by Trypsin-Binding Macroglobulin.∗

  1966cited by this paper
• Macroglobulin from Human Plasma Which Forms an Enzymaticaliy Active Compound with Trypsin

  1964cited by this paper
• Protein binding of pancreatic proteolytic enzymes.

  1962cited by this paper
• Investigation of serum trypsin and related substances. I. The quantitative demonstration of trypsinlike activity in human blood serum by a micromethod.

  1962cited by this paper
• [A new method for the determination of cholesterol linked to serum alpha-lipoproteins and beta-lipoproteins].

  1958cited by this paper
• Studies on the inhibition of proteolytic enzymes by serum. II. Demonstration that separate proteolytic inhibitors exist in serum; their distinctive properties and the specificity of their action.

  1952cited by this paper

• Dysregulated fibrinolysis and plasmin activation promote the pathogenesis of osteoarthritis

  2024cites this paper
• Tranexamic acid for haemostasis and beyond: does dose matter?

  2023cites this paper
• Anticoagulant and Thrombolytic Drugs I: Patho-Physiological and Pharmacological Aspects

  2012cites this paper
• THE INHIBITION O F UROKINASE BY ALPHA ,-MACROGLOBULIN

  2012cites this paper
• Antithrombotic Drugs: Part II

  2012cites this paper
• The Coagulation System in Children: Developmental and Pathophysiological Considerations

  2011cites this paper
• The effect of soy bean trypsin inhibitor on kaolin induced activation of factor VII.

  2009cites this paper
• Biochemistry and Clinical Role of Trypsinogens and Pancreatic Secretory Trypsin Inhibitor

  2006cites this paper
• Elevated serum trypsin binding activity in patients with hereditary pancreatitis

  2005cites this paper
• Discovery of alpha2-plasmin inhibitor and its congenital deficiency.

  2005cites this paper
• The properties of rabbit alpha1-macroglobulin upon activation are distinct from those of rabbit and human alpha2-macroglobulins.

  2005cites this paper
• Trypsinogens and trypsin inhibitor (PSTI/TATI) -expression in urogenital organs and tumors

  2001cites this paper
• Localization of the binding site for transforming growth factor-beta in human alpha2-macroglobulin to a 20-kDa peptide that also contains the bait region.

  1998cites this paper
• The pericardium and pericardial adhesions in relation to reoperative cardiac surgery

  1997cites this paper
• Chemical modification of alpha2-macroglobulin to generate derivatives that bind transforming growth factor-beta with increased affinity.

  1997cites this paper
• Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity.

  1995cites this paper
• Purification and characterization of three alpha 2-antiplasmin and alpha 2-macroglobulin inactivating enzymes from the venom of the Mexican west coast rattlesnake (Crotalus basiliscus).

  1995cites this paper
• Transforming growth factor beta isoform 2-specific high affinity binding to native alpha 2-macroglobulin. Chimeras identify a sequence that determines affinity for native but not activated alpha 2-macroglobulin.

  1994cites this paper
• Binding of platelet-derived growth factor-BB and transforming growth factor-beta 1 to alpha 2-macroglobulin in vitro and in vivo: comparison of receptor-recognized and non-recognized alpha 2-macroglobulin conformations.

  1993cites this paper
• Assessment of the Relative Contribution of Different Protease Inhibitors to the Inhibition of Plasmin In Vivo

  1993cites this paper
• Quantification of functional and inactivated alpha 2-macroglobulin in sepsis.

  1991cites this paper
• Kinin formation: mechanisms and role in inflammatory disorders.

  1988cites this paper
• Identification of a monoclonal antibody specific for a neoantigenic determinant on alpha 2-macroglobulin: use for the purification and characterization of binary proteinase-inhibitor complexes.

  1988cites this paper
• Alpha 2-macroglobulin is the primary inhibitor of miniplasmin in vitro and in vivo in the mouse. Comparison with alpha 2-antiplasmin in simultaneous reaction experiments.

  1988cites this paper
• Characterization of the reaction of plasmin with alpha 2-macroglobulin: effect of antifibrinolytic agents.

  1987cites this paper
• The coagulation-kinin pathway of human plasma.

  1987cites this paper
• Purification and characterization of human alpha 2-macroglobulin conformational variants by non-ideal high performance size-exclusion chromatography.

  1986cites this paper
• Species difference in the fibrinogenolytic effects of alpha- and beta-fibrinogenases from Trimeresurus mucrosquamatus snake venom.

  1985cites this paper
• Formation of the fibrin clot: the balance of procoagulant and inhibitory factors.

  1985cites this paper
• Distribution of alpha 2-macroglobulin in normal, inflammatory, and tumor tissues in rats.

  1984cites this paper
• The fibrinolytic system in man.

  1984cites this paper
• Synthetic peptide substrates in hemostatic testing.

  1983cites this paper
• Regulation of factor Xa in vitro in human and mouse plasma and in vivo in mouse. Role of the endothelium and plasma proteinase inhibitors.

  1983cites this paper
• Reaction of human alpha 2-macroglobulin half-molecules with plasmin as a probe of protease binding site structure.

  1983cites this paper
• Plasma coagulation proteases, proteolytic inhibitors, and their interaction with platelets.

  1982cites this paper
• Inhibition of human factor Xa by various plasma protease inhibitors.

  1982cites this paper
• Role of intrinsic inhibitors in acid-activation of inactive plasma renin (prorenin).

  1982cites this paper
• The presence and release of alpha 2-antiplasmin from human platelets.

  1981cites this paper
• Alpha2-plasmin inhibitor and alpha2-macroglobulin-plasmin complexes in plasma. Quantitation by an enzyme-linked differential antibody immunosorbent assay.

  1981cites this paper
• Studies on plasma antiplasmin activity using a new plasmin specific chromogenic tripeptide substrate.

  1979cites this paper
• [Interaction between alpha-2 macroglobulin and trypsin with synthetic trypsin inhibitors].

  1979cites this paper
• A sensitive fluorescent assay for determining alpha2-plasmin inhibitor using a synthetic substrate.

  1979cites this paper
• Studies on the Effect of Plasminogen Activator on the Interaction between α2-Macroglobulin and Plasmin

  1978cites this paper
• Antithrombin III activity in baboons

  1978cites this paper
• Changes in plasminogen levels, plasmin activity and activity of antiplasmins during endotoxin shock in dogs.

  1978cites this paper
• Binding of zinc to alpha-2-macroglobulin and its role in enzyme binding activity.

  1977cites this paper
• Plasmin inhibitor interactions. The effectiveness of alpha2-plasmin inhibitor in the presence of alpha2-macroglobulin

  1977cites this paper
• Amidolytic assay of thrombin bound to alpha2-macroglobulin in plasma.

  1977cites this paper
• Determination of a new rapid plasmin inhibitor in human blood by means of a plasmin specific tripeptide substrate.

  1977cites this paper
• Protease inhibitors and human plasmin: interaction in a whole plasma system.

  1977cites this paper
• Generation of an esterolytic and kinin-forming kallikrein-α2-macroglobulin complex in human serum by treatment with acetone

  1976cites this paper
• The high molecular weight proteins released from cultured cells.

  1976cites this paper
• The contribution of plasma protease inhibitors to antiplasmin activity in man.

  1976cites this paper
• Studies on Cystic Fibrosis Using Isoelectric Focusing. II. Demonstration of Deficient Proteolytic Cleavage of α2-Macroglobulin in Cystic Fibrosis Plasma

  1976cites this paper
• Mechanisms involved in enhancement of plasma fibrinolytic activity by chloroform.

  1976cites this paper
• Clofibrate-induced alterations in serum protein patterns.

  1976cites this paper
• Plasmin inactivation in Plasma

  1976cites this paper
• A Solid‐Phase Radioassay for the Quantitative Determination of Antiplasmin Activity in Human Plasma

  1975cites this paper
• Cationic proteins of human granulocytes. V. Interaction with plasma protease inhibitors.

  1975cites this paper
• Studies on human plasma C1 inactivator-enzyme interactions. I. Mechanisms of interaction with C1s, plasmin, and trypsin.

  1975cites this paper
• VARIATIONS OF PROTEASE INHIBITORS IN FOETUSES, NEWBORN INFANTS and IN SOME NEONATAL DISORDERS

  1975cites this paper
• Serum Inhibitors of Fibrinolysis

  1975cites this paper
• [Studies on human alpha-2 macroglobulin structure and its complexes with proteases, using polyacrylamide gel electrophoresis].

  1975cites this paper
• Uptake of proteinase-alpha-macroglobulin complexes by macrophages.

  1975cites this paper
• The action of antithrombin III on plasmin and activators of plasminogen.

  1975cites this paper
• Actions and interactions of antithrombin and heparin.

  1975cites this paper
• [Influence of rat serum alpha 1 macroglobulin on the enzymatic activity of trypsin and chymotrypsin].

  1975cites this paper
• Kinin-forming factors in acid-heat-treated human serum.

  1974cites this paper
• Excercise-induced fibrinolytic activity and its effect on the degradation of fibrinogen, fibrin and fibrin-like precipitates.

  1974cites this paper
• Cold-promoted activation of factor VII in human plasma: studies on the associated acyl-arginine esterase activity.

  1974cites this paper
• [Determination of plasminogen in human blood plasma].

  1974cites this paper
• Purification of a new plasma inhibitor of kallikrein.

  1974cites this paper
• The inhibition of human plasmin by human antithrombin-heparin cofactor.

  1974cites this paper
• The interaction of a naphthalene dye with 2 -macroglobulin, free or bound to trypsin.

  1973cites this paper
• Degradation of human fibrinogen by plasms alpha2-macroglobulin-enzyme complexes.

  1973cites this paper
• The inhibition of urokinase by alpha 2 -macroglobulin.

  1973cites this paper
• STUDIES ON HUMAN PLASMA α2-MACROGLOBULIN-ENZYME INTERACTIONS

  1973cites this paper
• Fibrinolysis in Cholestatic Jaundice

  1973cites this paper
• [Alpha2-macroglobulin concentration in the serum in chronic pancreatitis, liver cirrhosis and diabetes mellitus].

  1973cites this paper
• Antiplasmin Activity of Rat Serum Slow α‐Globulins

  1973cites this paper
• Abnormal fibrinolysis in familial pulmonary hypertension.

  1973cites this paper
• Effect of low-density lipoprotein preparations on plasmin.

  1973cites this paper
• Hereditary pancreatitis in a kinship associated with portal vein thrombosis.

  1972cites this paper
• Specificity of inhibitors lacking in alpha antitrypsin deficiency and hereditary angioedema toward human proteolytic enzymes.

  1972cites this paper
• Thio reduction of human 2 -macroglobulin. The subunit structure.

  1972cites this paper
• Inhibition of plasminogen activators by naturally occurring inhibitors in man.

  1972cites this paper
• Fibrinolytic activity in acute myocardial infarction.

  1972cites this paper
• Trypsin-binding -2-macroglobulin in patients with acute pancreatitis.

  1972cites this paper
• Studies on the interaction between collagen and a plasma kallikrein-like activity. Evidence for a surface-active enzyme system.

  1972cites this paper
• Inhibitors of kallikrein in human plasma.

  1972cites this paper
• Leg Ulcers and Liver Function Tests

  1972cites this paper
• [Plasma protease inhibitors].

  1971cites this paper
• Separation of plasma thromboplastin antecedent from kallikrein by the plasma 2 -macroglobulin, kallikrein inhibitor.

  1971cites this paper
• Human serum plasminogen antiactivator: its distinction from antiplasmin.

  1971cites this paper
• Serum alpha2-macroglobulin, transferrin, albumin, and IgG levels in preeclampsia

  1970cites this paper
• Effect of combined oestrogen-progestogen oral contraceptives on serum-levels of alpha 2-macroglobulin, transferrin, albumin, and IgG.

  1970cites this paper
• Inhibitors of the fibrinolytic enzyme system in renal disease.

  1970cites this paper
• Studies on alpha 2-macroglobulin in bovine plasma. I. Purification, physical properties, and chemical compositions.

  1970cites this paper
• Influence of an enzyme from aspergillus oryzae, protease I, on some components of the fibrinolytic system.

  1970cites this paper
• Plasma-proteins and oral contraceptives.

  1970cites this paper