Synthesis of acyl halides under very mild conditions

No abstract is available for this paper.

• Publication year

  1980

• Venue

  Journal of The Chemical Society, Chemical Communications

• Publication date

  1980-04-29

• Fields of study

  Chemistry

• Identifiers
  DOI 10.1039/C39790001180
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• No references are available for this paper.

• Examining the Role of Conformational Rigidity to Antibacterial Activity via Side-Chain Crosslinking of Amphiphilic Aromatic Oligoamides.

  2025cites this paper
• Evolutionary Efforts in the Total Synthesis of Pepluacetal.

  2025cites this paper
• Total Synthesis of the Marine Cyclic Depsipeptide Lagunamide D

  2025cites this paper
• Discovery of Clinical Candidate GLPG3970: A Potent and Selective Dual SIK2/SIK3 Inhibitor for the Treatment of Autoimmune and Inflammatory Diseases

  2024cites this paper
• The Divergent Reactivity of Acid Chlorides Under Transition Metal Catalysis

  2024cites this paper
• Optimized Properties and Synthesis of Photoactivatable Diazoketorhodamines Facilitate and Enhance High-Throughput Single-Molecule Tracking

  2024cites this paper
• Modular Access to Bifunctional Norbornenes and Their Application in Ring-Opening Metathesis Polymerization

  2023cites this paper
• Metabolic, toxicological, chemical, and commercial perspectives on esterification of dietary polyphenols: a review

  2023cites this paper
• Total Synthesis of the Reported Structure of Cahuitamycin A: Insights into an Elusive Natural Product Scaffold

  2023cites this paper
• Synthetic Efforts and Ultimate Limitation to an Asymmetric Achmatowicz Approach Toward EBC-23.

  2022cites this paper
• Isolation and Total Synthesis of Beru'amide, an Antitrypanosomal Polyketide from a Marine Cyanobacterium Okeania sp.

  2022cites this paper
• Modular Chemical Synthesis of Streptogramin and Lankacidin Antibiotics.

  2021cites this paper
• The Chosen Few: Parallel Library Reaction Methodologies for Drug Discovery.

  2021cites this paper
• A mild method for the replacement of a hydroxyl group by halogen: 3. the dichotomous behavior of α-haloenamines towards allylic and propargylic alcohols

  2021cites this paper
• N-Amination Converts Amyloidogenic Tau Peptides into Soluble Antagonists of Cellular Seeding.

  2021cites this paper
• N-Alkylated Aromatic Poly- and Oligoamides.

  2021cites this paper
• Modular Synthesis of Streptogramin Antibiotics

  2020cites this paper
• Pd‐Catalyzed Asymmetric N‐Allylation of Amino Acid Esters with Exceptional Levels of Catalyst Control: Stereo‐Divergent Synthesis of ProM‐15 and Related Bicyclic Dipeptide Mimetics

  2020cites this paper
• Chemistry of C  C Bond Formation Reactions Used in Biomass Upgrading: Reaction Mechanisms, Site Requirements, and Catalytic Materials

  2020cites this paper
• A mild method for the replacement of a hydroxyl group by halogen: 2. unified procedure and stereochemical studies

  2020cites this paper
• Total Synthesis of the Reported Structure of Cahuitamycin A

  2020cites this paper
• Aza-Amino Acids Disrupt β-Sheet Secondary Structures

  2019cites this paper
• Total Synthesis of Caprazamycin A: Practical and Scalable Synthesis of syn-β-Hydroxyamino Acids and Introduction of a Fatty Acid Side Chain to 1,4-Diazepanone.

  2019cites this paper
• Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies.

  2019cites this paper
• Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma

  2019cites this paper
• A lifetime journey into the world of chemistry

  2019cites this paper
• Formamide catalyzed activation of carboxylic acids – versatile and cost-efficient amidation and esterification

  2019cites this paper
• Synthesis and Application of Photoreactive Collagen Peptides, and Antiparasitic Agents

  2018cites this paper
• Traditional and New methods for the Preparation of Diazocarbonyl Compounds.

  2018cites this paper
• Cobaltocenium substituents as electron acceptors in photosynthetic model dyads

  2017cites this paper
• Modular, Scalable Synthesis of Group A Streptogramin Antibiotics.

  2017cites this paper
• Visible-Light-Initiated Manganese Catalysis for C-H Alkylation of Heteroarenes: Applications and Mechanistic Studies.

  2017cites this paper
• Discovery of spiro[indole-3,2'-pyrrolidin]-2(1H)-one based inhibitors targeting Brr2, a core component of the U5 snRNP.

  2017cites this paper
• Formal Total Synthesis of (±)-Strictamine by [2,3]-Sigmatropic Stevens Rearrangements.

  2017cites this paper
• One-pot synthesis of amides from carboxylic acids activated using thionyl chloride

  2016cites this paper
• The practical synthesis of β-acyl glucuronides by using allyl 2,3,4-tri-(O-allyloxycarbonyl)-d-glucuronate and 1-chloro-N,N,2-trimethyl-1-propenylamine

  2016cites this paper
• Total Syntheses of Nannocystins A and A0, Two Elongation Factor 1 Inhibitors.

  2016cites this paper
• Synthesis of Natural and Unnatural Cyclooligomeric Depsipeptides Enabled by Flow Chemistry

  2016cites this paper
• Synthesis of CPZEN-45: Construction of the 1,4-Diazepin-2-one Core by the Cu-Catalyzed Intramolecular Amidation of a Vinyl Iodide.

  2016cites this paper
• A mild method for the replacement of a hydroxyl group by halogen. 1. Scope and chemoselectivity

  2016cites this paper
• Synthesis and Self-Assembly of Discrete Dimethylsiloxane-Lactic Acid Diblock Co-oligomers: The Dononacontamer and Its Shorter Homologues.

  2016cites this paper
• Fates of imine intermediates in radical cyclizations of N-sulfonylindoles and ene-sulfonamides

  2015cites this paper
• New solid phase submonomer synthesis of arylopeptoid oligomers using reductive amination

  2015cites this paper
• Total synthesis of (-)-caprazamycin A.

  2015cites this paper
• Probing o-diphenylphosphanyl benzoate (o-DPPB)-directed C-C bond formation: total synthesis of dictyostatin.

  2015cites this paper
• Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

  2015cites this paper
• FimH antagonists: bioisosteres to improve the in vitro and in vivo PK/PD profile.

  2015cites this paper
• Ester coupling reactions--an enduring challenge in the chemical synthesis of bioactive natural products.

  2015cites this paper
• Amino Acid Chlorides: A Journey from Instability and Racemization Toward Broader Utility in Organic Synthesis Including Peptides and Their Mimetics

  2015cites this paper
• Synthesis of indole-derived allocolchicine congeners exhibiting pronounced anti-proliferative and apoptosis-inducing properties

  2015cites this paper
• Utilizing CYP2D6 and BACE1 Structure Complexes to Reduce Risk of Drug-Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

  2015cites this paper
• One-pot synthesis of α-ketoacetals from aryl methyl ketones in the presence of selenous acid catalyzed by boron trifluoride etherate

  2015cites this paper
• Aminoferrocene and Ferrocene Amino Acid as Electron Donors in Modular Porphyrin-Ferrocene and Porphyrin-Ferrocene-Porphyrin Conjugates

  2014cites this paper
• Rearrangement Reactions of 1,1-Divinyl-2-phenylcyclopropanes

  2014cites this paper
• Synthesis of Indole-Derived Allocolchicine Congeners through Pd-Catalyzed Intramolecular C-H Arylation Reaction

  2014cites this paper
• Development of a Total Telescoped Synthesis of a Renin Inhibitor Containing 3,4,5-Substituted Piperidine with Sterically Hindered Amide Bonds

  2014cites this paper
• Triple helix formation in amphiphilic discotics: demystifying solvent effects in supramolecular self-assembly.

  2014cites this paper
• Synthesis of enantiomerically pure model compounds of the glucose-6-phosphate-T1-translocase inhibitors kodaistatins A–D. Inferences with regard to the stereostructure of the natural products

  2013cites this paper
• Intramolecular cycloaddition reactions of cis-1,2-dihydrocatechol derivatives incorporating C3-tethered diazoketones, nitrile oxides, and azides: stereocontrolled routes to enantiomerically pure spiro[5.5]undecanes and related systems.

  2013cites this paper
• Porphyrin amino acids-amide coupling, redox and photophysical properties of bis(porphyrin) amides.

  2013cites this paper
• Synthesis of allocolchicinoids: a 50 year journey

  2013cites this paper
• 3-Substituted Prolines: From Synthesis to Structural Applications, from Peptides to Foldamers †

  2013cites this paper
• Synthesis of the spiroketal core of integramycin

  2013cites this paper
• Synthesis of 8-desmethoxy psymberin: a putative biosynthetic intermediate towards the marine polyketide psymberin.

  2013cites this paper
• Dichlorosilylene: a high temperature transient species to an indispensable building block.

  2013cites this paper
• Synthesis of enantioenriched tertiary boronic esters from secondary allylic carbamates. Application to the synthesis of C30 botryococcene.

  2012cites this paper
• Studies on the Total Synthesis of Lactonamycin: Synthesis of the Fused Pentacyclic B–F Ring Unit

  2012cites this paper
• The Evolution of a Strategy for the Total Synthesis of Hirsutellone B

  2012cites this paper
• Donor-acceptor stabilized silaformyl chloride.

  2012cites this paper
• A novel approach toward the synthesis of strigolactones through intramolecular [2+2] cycloaddition of ketenes and ketene-iminiums to olefins. Application to the asymmetric synthesis of GR-24

  2012cites this paper
• Synthesis of highly oxidized quinolizidine via reduction of acylpyridinium cations, and total syntheses of quinolizidines 207I and 1-epi-207I.

  2012cites this paper
• From Planning to Optimization: Total Synthesis of Valerenic Acid and Some Bioactive Derivatives

  2012cites this paper
• Synthesis and biological characterization of a series of novel diaryl amide M₁ antagonists.

  2012cites this paper
• Efficient Preparation of α-Ketoacetals

  2012cites this paper
• Total synthesis of indole-derived allocolchicine analogues exhibiting strong apoptosis-inducing activity.

  2012cites this paper
• Peptide coupling reagents, more than a letter soup.

  2011cites this paper
• Synthesis and Evaluation of 5-Fluoro-2-aryloxazolo[5,4-b]pyridines as β-Amyloid PET Ligands and Identification of MK-3328.

  2011cites this paper
• Enabling the Development of N-Heterocyclic Carbene (NHC) Catalyzed Reactions: Practical Methods for the Preparation of 1-Acyl-2-Alkylcycloalkenes from Cycloalkanones

  2011cites this paper
• Efficient syntheses of 25,26-dihydrodictyostatin and 25,26-dihydro-6-epi-dictyostatin, two potent new microtubule-stabilizing agents

  2011cites this paper
• Ethyl-2-(2-chloroethyl)acrylate: a new very versatile α-cyclopropylester cation synthon. Efficient synthesis of cyclopropane ester derivatives by Michael addition-induced cyclization reaction

  2011cites this paper
• Bicyclic imidazolidinones as potential antibiotics

  2010cites this paper
• Total synthesis of (-)-dictyostatin, a microtubule-stabilising anticancer macrolide of marine sponge origin

  2010cites this paper
• “Tail–Tail Dimerization” of Ferrocene Amino Acid Derivatives

  2010cites this paper
• N-alkylated oligoamide alpha-helical proteomimetics.

  2010cites this paper
• A mild and general one-pot preparation of cyanoethyl-protected tetrazoles

  2010cites this paper
• Streamlined syntheses of (-)-dictyostatin, 16-desmethyl-25,26-dihydrodictyostatin, and 6-epi-16-desmethyl-25,26-dihydrodictyostatin.

  2010cites this paper
• Nucleophilic acyl substitution via aromatic cation activation of carboxylic acids: rapid generation of acid chlorides under mild conditions.

  2010cites this paper
• Synthesis-driven mapping of the dictyodendrin alkaloids

  2009cites this paper
• Total synthesis and biological evaluation of novel C2-C6 region analogues of dictyostatin.

  2009cites this paper
• Macrolide-based microtubule-stabilizing agents - chemistry and structure-activity relationships.

  2009cites this paper
• A diastereoselective route to 2,6-syn-disubstituted tetrahydropyrans: synthesis of the civet compound (+)-2-((2S,6S)-6-methyltetrahydro-2H-pyran-2-yl) acetic acid.

  2009cites this paper
• 2,4-Diaminopyridine delta-opioid receptor agonists and their associated hERG pharmacology.

  2009cites this paper
• Resorcylic lactone L-783277 as a new lead structure for kinase inhibition: total synthesis and SAR studies

  2009cites this paper
• Ring-closing metathesis for the synthesis of heteroaromatics: evaluating routes to pyridines and pyridazines

  2009cites this paper
• Cl3CCONH2/PPh3: A Versatile Reagent for Synthesis of Esters

  2008cites this paper
• Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin.

  2008cites this paper
• Total synthesis and biological evaluation of potent analogues of dictyostatin: modification of the C2-C6 dienoate region.

  2008cites this paper
• Steroid template associated peptides: design, synthesis and 2D NMR characterization of a novel protected 18-Phe,19-Gly-containing steroidal compound

  2007cites this paper
• Reactivity of chlorinating agents/PPh3 for the chlorination of alcohols and carboxylic acids: a comparative study

  2007cites this paper
• Tandem oxime formation- : epoxide ring opening sequences for the preparation of oxazines related to the trichodermamides

  2007cites this paper