Cigarette Smoke-Induced Failure of Apoptosis Resulting in Enhanced Neoplastic Transformation in Human Bronchial Epithelial Cells

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Toxicology and Environmental Health, Part A

• Publication date

  2012-06-15

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1080/15287394.2012.690088PMID 22757675
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Interactive Effect of Cigarette Smoke Extract and World Trade Center Dust Particles on Airway Cell Cytotoxicity

  2011cited by this paper
• Chronic exposure to cigarette smoke condensate in vitro induces epithelial to mesenchymal transition-like changes in human bronchial epithelial cells, BEAS-2B.

  2011cited by this paper
• Hallmarks of cancer: the next generation.

  2011cited by this paper
• The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients.

  2010cited by this paper
• Endogenous tumor suppression mediated by PTEN involves survivin gene silencing.

  2009cited by this paper
• The effect of different doses of cigarette smoke in a mouse lung tumor model.

  2009cited by this paper
• Alteration of transcriptional profile in human bronchial epithelial cells induced by cigarette smoke condensate.

  2009cited by this paper
• Temozolomide preferentially depletes cancer stem cells in glioblastoma.

  2008cited by this paper
• Nicotine inhibits apoptosis induced by cisplatin in human oral cancer cells.

  2007cited by this paper
• A Review of the Histopathology of Cigarette Smoke–Induced Lung Cancer in Rats and Mice

  2007cited by this paper
• PSGL-1-mediated activation of EphB4 increases the proangiogenic potential of endothelial progenitor cells.

  2007cited by this paper
• Aberrant promoter methylation of p16 and MGMT genes in lung tumors from smoking and never-smoking lung cancer patients.

  2006cited by this paper
• Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin.

  2006cited by this paper
• Mitochondrial membrane permeabilization: the sine qua non for cell death.

  2006cited by this paper
• Nicotine prevents the apoptosis induced by menadione in human lung cancer cells.

  2006cited by this paper
• The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death.

  2005cited by this paper
• A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes

  2005cited by this paper
• Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers

  2005cited by this paper
• Involvement of the RASSF1A tumor suppressor gene in controlling cell migration.

  2005cited by this paper
• Carcinogenicity studies of inhaled cigarette smoke in laboratory animals: old and new.

  2005cited by this paper
• Role of the Ras-association domain family 1 tumor suppressor gene in human cancers.

  2005cited by this paper
• Prognostic Significance of Anti-apoptosis Proteins Survivin and bcl-2 in Non-small Cell Lung Carcinomas: A Clinicopathologic Study of 102 Cases

  2004cited by this paper
• the Effect of

  2004cited by this paper
• Nuclear localization of survivin is a positive prognostic factor for survival in advanced non-small-cell lung cancer.

  2004cited by this paper
• Genome-Scale Analysis of Lung Cancer Progression

  2004cited by this paper
• Gene silencing in cancer in association with promoter hypermethylation.

  2003cited by this paper
• Malignant transformation of human bronchial epithelial cells with the tobacco‐specific nitrosamine, 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone

  2003cited by this paper
• Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma.

  2003cited by this paper
• Patterns of allelic loss differ in lung adenocarcinomas of smokers and nonsmokers.

  2003cited by this paper
• The fundamental role of epigenetic events in cancer

  2002cited by this paper
• DNA adduct burden and tobacco carcinogenesis

  2002cited by this paper
• The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1

  2002cited by this paper
• Behavioural genetics: Worms gang up on bacteria

  2002cited by this paper
• The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1

  2002cited by this paper
• Focus on lung cancer.

  2002cited by this paper
• Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers.

  2002cited by this paper
• BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl

  2002cited by this paper
• Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma.

  2002cited by this paper
• Interactions between methylating and pyridyloxobutylating agents in A/J mouse lungs: implications for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.

  2001cited by this paper
• [Molecular basis of carcinogenesis in lung cancer induced by cigarette smoking].

  2001cited by this paper
• Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression.

  2001cited by this paper
• [Mitochondrial control of apoptosis].

  2001cited by this paper
• Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3

  2000cited by this paper
• Repair of O(6)-alkylguanine by alkyltransferases.

  2000cited by this paper
• [Mitochondria and apoptosis].

  2000cited by this paper
• Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death

  2000cited by this paper
• Caspases - controlling intracellular signals by protease zymogen activation.

  2000cited by this paper
• Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.

  2000cited by this paper
• Ras Uses the Novel Tumor Suppressor RASSF1 as an Effector to Mediate Apoptosis*

  2000cited by this paper
• Repair of O6-alkylguanine by alkyltransferases

  2000cited by this paper
• Occupational and environmental risk factors for idiopathic pulmonary fibrosis: a multicenter case-control study. Collaborating Centers.

  2000cited by this paper
• Hypermethylation of tumor suppressor genes in cancer.

  1999cited by this paper
• Estradiol Modulates bcl-2 in Cerebral Ischemia: A Potential Role for Estrogen Receptors

  1999cited by this paper
• Tobacco smoke carcinogens and lung cancer.

  1999cited by this paper
• Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.

  1999cited by this paper
• Alterations in DNA methylation: a fundamental aspect of neoplasia.

  1998cited by this paper
• Mitochondria and apoptosis.

  1998cited by this paper
• The changing cigarette, 1950-1995.

  1997cited by this paper
• Mitochondrial control of apoptosis.

  1997cited by this paper
• Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

  1996cited by this paper
• Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo

  1995cited by this paper
• Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids.

  1989cited by this paper
• Pathobiological effects of acrolein in cultured human bronchial epithelial cells.

  1988cited by this paper
• Evaluation of the biological activity of cigarette-smoke condensate fractions using six in vitro short-term tests.

  1984cited by this paper

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  2025cites this paper
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  2024cites this paper
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  2023cites this paper
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  2022cites this paper
• miR-200b upregulation promotes migration of BEAS-2B cells following long-term exposure to cigarette smoke by targeting ETS1

  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
• Multi-platform analysis of methylation-regulated genes in human lung adenocarcinoma

  2019cites this paper
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  2019influential citation
• LEVELS OF SERUM M30 AND M65 PROTEINS AS BIOMARKERS OF APOPTOSIS IN CHILDREN EXPOSED TO PASSIVE SMOKING

  2018cites this paper
• A Prospective Study of Smoking and Risk of Synchronous Colorectal Cancers

  2017cites this paper
• DAMPs, endogenous danger signals fueling airway inflammation in COPD

  2017cites this paper
• Functional Effects of Cigarette Smoke‐Induced Changes in Airway Smooth Muscle Mitochondrial Morphology

  2017cites this paper
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  2016cites this paper
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  2016cites this paper
• Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures

  2015cites this paper
• Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release.

  2015cites this paper
• Roflumilast N-oxide inhibits bronchial epithelial to mesenchymal transition induced by cigarette smoke in smokers with COPD.

  2014cites this paper
• Continual Exposure to Cigarette Smoke Extracts Induces Tumor-Like Transformation of Human Nontumor Bronchial Epithelial Cells in a Microfluidic Chip

  2014cites this paper
• A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification.

  2013cites this paper