S. Wölfl

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Aliases
S Wölfl, Stefan Wölfl, S. Wölfl, Stefan Wölfl, Stefan. Wölfl
Publication record
217 papers · 7,869 citations · H-index 47

PAPERS

Elucidating the Multimodal Anticancer Mechanism of an Organometallic Terpyridine Platinum(II) N-Heterocyclic Carbene Complex against Triple-Negative Breast Cancer In Vitro and In Vivo.
202312 citationsauthor #12
Development of a next-generation endogenous OCT4 inducer and its anti-aging effect in vivo.
20237 citationsauthor #10
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis
2022158 citationsauthor #35
Oxygen Gradient Induced in Microfluidic Chips Can Be Used as a Model for Liver Zonation
20228 citationsauthor #9
Real-time monitoring of immediate drug response and adaptation upon repeated treatment in a microfluidic chip system
20226 citationsauthor #9
Cell Type-Specific Metabolic Response to Amino Acid Starvation Dictates the Role of Sestrin2 in Regulation of mTORC1
20224 citationsauthor #4
Development of an Artificial 3D Liver Phantom for Analysis of Radiotherapeutic Effects In Vitro
20222 citationsauthor #5
MYCN mediates cysteine addiction and sensitizes to ferroptosis
20211 citationsauthor #26
Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells
202128 citationsauthor #5
Continuous optical in‐line glucose monitoring and control in CHO cultures contributes to enhanced metabolic efficiency while maintaining darbepoetin alfa product quality
202110 citationsauthor #7
Genetic Manipulation of FBP1 Expression in Breast Cancer Cells Reveals the Potential of FBP1 to Disrupt The Warburg Effect, and Nutrient Mediated Adaptive Post-Translational Regulation of FBP1 Protein Levels.
20210 citationsauthor #3
pVHL-mediated SMAD3 degradation suppresses TGF-β signaling
202113 citationsauthor #13
Severe metabolic alterations in liver cancer lead to ERK pathway activation and drug resistance
202047 citationsauthor #22
NHC-gold compounds mediate immune suppression through induction of AHR-TGFβ1 signalling in vitro and in scurfy mice
202015 citationsauthor #21
A Multitarget Gold(I) Complex Induces Cytotoxicity Related to Aneuploidy in HCT‐116 Colorectal Carcinoma Cells
202045 citationsauthor #7
Ascorbate kills breast cancer cells by rewiring metabolism via redox imbalance and energy crisis.
202034 citationsauthor #12
In vitro metabolic activation of vitamin D3 by using a multi-compartment microfluidic liver-kidney organ on chip platform
201945 citationsauthor #7
New gold compound shows immunesuppressive functions and leads to an amelioration of skin inflammation
20190 citationsauthor #5
p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells
201935 citationsauthor #6
Role of matrix metalloproteinase-9 in cystic fibrosis lung disease and evaluation of therapeutic strategies
20190 citationsauthor #1
NHC-gold compounds mediate immune suppression through induction of AHR-TGFÎ21 signalling in vitro and in scurfy mice
20199 citationsauthor #21
Monitoring cytochrome P450 activity in living hepatocytes by chromogenic substrates in response to drug treatment or during cell maturation
20188 citationsauthor #12
Liver-Kidney-on-Chip To Study Toxicity of Drug Metabolites.
2018115 citationsauthor #13
A Ruthenium(II) N-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway
201836 citationsauthor #7
Guidelines and recommendations on yeast cell death nomenclature
2018170 citationsauthor #81
Correction to: Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours
20185 citationsauthor #9
Author Correction: Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress
20180 citationsauthor #3
TGF-β2 abundance in mice and men:A successful anti-TGF-β2 strategy in biliary-derived liver disease
20180 citationsauthor #3
Expression of TXNIP in Cancer Cells and Regulation by 1,25(OH)2D3: Is It Really the Vitamin D3 Upregulated Protein?
201817 citationsauthor #3
Fluorescent organometallic rhodium(I) and ruthenium(II) metallodrugs with 4-ethylthio-1,8-naphthalimide ligands: Antiproliferative effects, cellular uptake and DNA-interaction.
201845 citationsauthor #8
Author Correction: Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress
20183 citationsauthor #3
Activation of pro-survival metabolic networks by 1,25(OH)2D3 does not hamper the sensitivity of breast cancer cells to chemotherapeutics
201817 citationsauthor #7
Transcription of human c-myc in permeabilized nuclei is associated with formation of Z-ONA in three discrete regions of the gene
20180 citationsauthor #2
Golgi stress mediates redox imbalance and ferroptosis in human cells
2018137 citationsauthor #6
Ascorbic acid kills breast cancer cells by reprogramming metabolism via a RedOx dependent mechanism
20181 citationsauthor #5
Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis
201827 citationsauthor #9
Abstract 4973: MYCN mediates cysteine addiction and sensitizes to ferroptosis in cancer cells
20180 citationsauthor #16
Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours
2018124 citationsauthor #9
Effects of 1 , 25 ( OH ) 2 D 3 on Cancer Cells and Potential Applications in Combination with Established and Putative Anti-Cancer Agents
201812 citationsauthor #2
Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule.
201738 citationsauthor #8
Mutational analysis of fructose-1,6-bis-phosphatase FBP1 indicates partially independent functions in gluconeogenesis and sensitivity to genotoxic stress
201710 citationsauthor #4
Microfluidic devices for stem-cell cultivation, differentiation and toxicity testing
20174 citationsauthor #5
Bioinformatic tools for the prediction of key regulatory molecules in signal transduction networks
20170 citationsauthor #3
Differences in p53 status significantly influence the cellular response and cell survival to 1,25‐dihydroxyvitamin D3‐metformin cotreatment in colorectal cancer cells
201732 citationsauthor #5
Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress
201739 citationsauthor #3
Effects of 1,25(OH)2D3 on Cancer Cells and Potential Applications in Combination with Established and Putative Anti-Cancer Agents
201726 citationsauthor #2
Di (2-Ethylhexyl) Phthalate and Its Role in Developing Cholestasis: An In Vitro Study on Different Liver Cell Types
201722 citationsauthor #7
1,25(OH)2D3 disrupts glucose metabolism in prostate cancer cells leading to a truncation of the TCA cycle and inhibition of TXNIP expression.
201735 citationsauthor #5
Design and fabrication of a scalable liver-lobule-on-a-chip microphysiological platform
2017130 citationsauthor #4
Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis
201722 citationsauthor #6
Optical biosensor optimized for continuous in-line glucose monitoring in animal cell culture
201739 citationsauthor #6
Vitamin D as a Novel Regulator of Tumor Metabolism: Insights on Potential Mechanisms and Implications for Anti-Cancer Therapy
201743 citationsauthor #2
Acidic stress induced G1 cell cycle arrest and intrinsic apoptotic pathway in Jurkat T‐lymphocytes
20177 citationsauthor #3
Monitoring cytochrome P450 activity in living hepatocytes by chromogenic substrates in response to drug treatment or during cell maturation
20171 citationsauthor #12
Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress
20172 citationsauthor #3
Bioinformatic Tool for the Analysis of Time-Resolved data: the TReCCA Analyser
20170 citationsauthor #4
BMP2 Transfer to Neighboring Cells and Activation of Signaling
20164 citationsauthor #4
A multi-target caffeine derived rhodium(i) N-heterocyclic carbene complex: evaluation of the mechanism of action.
201648 citationsauthor #6
Modified STAP conditions facilitate bivalent fate decision between pluripotency and apoptosis in Jurkat T-lymphocytes.
20162 citationsauthor #4
Alkynyl gold(I) phosphane complexes: Evaluation of structure-activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex.
201655 citationsauthor #12
The new facile and straightforward method for the synthesis of 4H-1,2,3-thiadiazolo[5,4-b]indoles and determination of their antiproliferative activity.
201610 citationsauthor #8
Multimodal Eph/Ephrin signaling controls several phases of urogenital development.
201612 citationsauthor #9
Evolving Insights on Metabolism, Autophagy, and Epigenetics in Liver Myofibroblasts
201620 citationsauthor #3
Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs
201639 citationsauthor #16
Procarcinogens – Determination and Evaluation by Yeast-Based Biosensor Transformed with Plasmids Incorporating RAD54 Reporter Construct and Cytochrome P450 Genes
201614 citationsauthor #11
Vesicular disruption of lysosomal targeting organometallic polyarginine bioconjugates.
201520 citationsauthor #5
Genotoxicity of Chemical Compounds Identification and Assessment by Yeast Cells Transformed With GFP Reporter Constructs Regulated by the PLM2 or DIN7 Promoter
201512 citationsauthor #9
Rhodium(I) N-Heterocyclic Carbene Bioorganometallics as in Vitro Antiproliferative Agents with Distinct Effects on Cellular Signaling.
201540 citationsauthor #9
In vitro generation of 3-dimensional organoid liver structures using differentiatedhuman cells
20150 citationsauthor #6
Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and Derivatives as Potent Oct3/4 Inducers.
201518 citationsauthor #16
Time-Resolved Cell Culture Assay Analyser (TReCCA Analyser) for the Analysis of On-Line Data: Data Integration—Sensor Correction—Time-Resolved IC50 Determination
20156 citationsauthor #4
Ethyl 2-((4-Chlorophenyl)amino)thiazole-4-carboxylate and Derivatives Are Potent Inducers of Oct3/4.
201519 citationsauthor #16
Simultaneous detection of multiple bioactive pollutants using a multiparametric biochip for water quality monitoring.
201511 citationsauthor #5
In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells
201592 citationsauthor #6
1 Title : Simultaneous detection of multiple bioactive pollutants using a multiparametric biochip for water quality monitoring
20150 citationsauthor #5
Towards a New Semantics for Possibilistic Answer Sets
20143 citationsauthor #3
Gold(I) N‐Heterocyclic Carbene Complexes with Naphthalimide Ligands as Combined Thioredoxin Reductase Inhibitors and DNA Intercalators
201456 citationsauthor #5
Neuroprotection by rAAV-mediated gene transfer of bone morphogenic protein 7
20141 citationsauthor #5
A deadly organometallic luminescent probe: anticancer activity of a ReI bisquinoline complex.
201474 citationsauthor #13
The Plant Decapeptide OSIP108 Can Alleviate Mitochondrial Dysfunction Induced by Cisplatin in Human Cells
20143 citationsauthor #11
Structure–Activity Relationship of Trifluoromethyl‐Containing Metallocenes: Electrochemistry, Lipophilicity, Cytotoxicity, and ROS Production
201425 citationsauthor #4
A TrxR inhibiting gold(I) NHC complex induces apoptosis through ASK1-p38-MAPK signaling in pancreatic cancer cells
2014111 citationsauthor #7
Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ
201440 citationsauthor #8
On Qualitative Route Descriptions
20140 citationsauthor #2
Detailed analysis of pro-apoptotic signaling and metabolic adaptation triggered by a N-heterocyclic carbene-gold(I) complex.
201448 citationsauthor #8
7,7'-Diazaindirubin--a small molecule inhibitor of casein kinase 2 in vitro and in cells.
201437 citationsauthor #5
A TrxR inhibiting gold(I) NHC complex induces apoptosis through ASK1-p38-MAPK signaling in pancreatic cancer cells
20140 citationsauthor #7
On the Scope of Qualitative Constraint Calculi
201411 citationsauthor #3
Neuroprotection by rAAV-mediated gene transfer of bone morphogenic protein 7
201411 citationsauthor #5
Zonation of Nitrogen and Glucose Metabolism Gene Expression upon Acute Liver Damage in Mouse
201346 citationsauthor #6
Quantitative kinetics analysis of BMP2 uptake into cells and its modulation by BMP antagonists
201341 citationsauthor #8
Evaluation of arene ruthenium(II) N-heterocyclic carbene complexes as organometallics interacting with thiol and selenol containing biomolecules.
2013101 citationsauthor #10
The CF-modifying gene EHF promotes p.Phe508del-CFTR residual function by altering protein glycosylation and trafficking in epithelial cells
201332 citationsauthor #4
Bone morphogenetic protein‐9 induces epithelial to mesenchymal transition in hepatocellular carcinoma cells
201375 citationsauthor #17
On the Propagation Strength of SAT Encodings for Qualitative Temporal Reasoning
201310 citationsauthor #3
BMP‐9 induces EMT in hepatocellular carcinoma cells. Immunofluorescent staining against BMP‐9 (green) and E‐cadherin (red) of a hepatocellular carcinoma section from TNFα/cmyc bitransgenic mouse
20131 citationsauthor #17
A fast and efficient polymerase chain reaction‐based method for the preparation of in situ hybridization probes
201215 citationsauthor #7
A spontaneous gold(I)-azide alkyne cycloaddition reaction yields gold-peptide bioconjugates which overcome cisplatin resistance in a p53-mutant cancer cell line
201293 citationsauthor #5
Acetic acid treatment in S. cerevisiae creates significant energy deficiency and nutrient starvation that is dependent on the activity of the mitochondrial transcriptional complex Hap2-3-4-5
201221 citationsauthor #7
An Automatic Decomposition Method for Qualitative Spatial and Temporal Reasoning
20123 citationsauthor #3

TIMELINE

1987 4 citations

1990 0 citations

1991 37 citations

1994 65 citations

1996 508 citations

1997 96 citations

1998 82 citations

1999 189 citations

2000 354 citations

2002 143 citations

2003 306 citations

2004 148 citations

2005 167 citations

2006 78 citations

2007 204 citations

2008 687 citations

2009 574 citations

2010 386 citations

2011 610 citations

2012 442 citations

2013 306 citations

2014 420 citations

2015 218 citations

2016 204 citations

2017 450 citations

2018 717 citations

2019 89 citations

2020 141 citations

2021 52 citations

2022 178 citations

2023 19 citations

Unknown 2 citations

S. Wölfl

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