H. Jumaa

Author Correction: BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition
20260 citationsauthor #15
P1222: ANTIGEN-INDEPENDENT, CELL-AUTONOMOUS SIGNALING IN SPLENIC MARGINAL ZONE LYMPHOMA
20231 citationsauthor #10
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia
202310 citationsauthor #20
Antigen-Independent, Autonomous B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma
20220 citationsauthor #13
Rheumatoid factor IgM autoantibodies control IgG homeostasis
202219 citationsauthor #8
B-cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia
20228 citationsauthor #7
Adaptive tolerance: Protection through self‐recognition
20226 citationsauthor #2
Autonomous BCR Signaling and Genetic Aberrations in CLL-Phenotype Monoclonal B Lymphocytosis in Siblings of CLL Patients
20220 citationsauthor #14
The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells
20224 citationsauthor #22
Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B-cell Precursor Acute Lymphoblastic Leukemia
20224 citationsauthor #18
CCND3 is indispensable for the maintenance of B-cell acute lymphoblastic leukemia
202217 citationsauthor #6
Glycan-mediated activation of B cells in chronic lymphocytic leukaemia subsets
20220 citationsauthor #5
S136: CONSTITUTIVE VLA-4 ACTIVATION IN CHRONIC LYMPHOCYTIC LEUKEMIA. THE OTHER SIDE OF BCR AUTONOMOUS SIGNALING.
20220 citationsauthor #16
Autoreactive antibodies control blood glucose by regulating insulin homeostasis
202214 citationsauthor #9
Immunoglobulin Gene Sequence as an Inherited and Acquired Risk Factor for Chronic Lymphocytic Leukemia
20225 citationsauthor #2
The Determinants of B Cell Receptor Signaling as Prototype Molecular Biomarkers of Leukemia
20214 citationsauthor #3
Primary Immune Responses and Affinity Maturation Are Controlled by IgD
202117 citationsauthor #7
Antibody-mediated procoagulant platelets in SARS-CoV-2-vaccination associated immune thrombotic thrombocytopenia
2021114 citationsauthor #13
CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia
202131 citationsauthor #21
B cell receptor isotypes differentially associate with cell signaling, kinetics, and outcome in chronic lymphocytic leukemia
202113 citationsauthor #14
Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B Cell Precursor Acute Lymphoblastic Leukemia
20210 citationsauthor #14
Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer.
202125 citationsauthor #24
Accumulation of the GSK3 target protein β-catenin is lethal for B cell precursors and malignant B cells
20210 citationsauthor #5
Antibodies control metabolism by regulating insulin homeostasis
20211 citationsauthor #9
CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia
20210 citationsauthor #21
Defective Allelic Exclusion by IgD in the Absence of Autoantigen
20213 citationsauthor #7
Kindlin‐3 maintains marginal zone B cells but confines follicular B cell activation and differentiation
20213 citationsauthor #15
Memory IgM protects endogenous insulin from autoimmune destruction
202112 citationsauthor #2
An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation
202039 citationsauthor #15
IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling
202071 citationsauthor #39
Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia
202018 citationsauthor #21
Lgr5-mediated restraint of β-catenin is essential for B-lymphopoiesis and leukemia-initiation
20202 citationsauthor #19
N-linked glycosylation selectively regulates autonomous pre-BCR function
20200 citationsauthor #1
Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation
20190 citationsauthor #13
Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins
201929 citationsauthor #12
The VLA-4 Integrin Is Constitutively Activated in a Fraction of CD49d-Expressing Chronic Lymphocytic Leukemia Via Autonomous BCR-Mediated Signaling
20191 citationsauthor #20
Pten controls B‐cell responsiveness and germinal center reaction by regulating the expression of IgD BCR
201935 citationsauthor #13
Co-Expression of SYK and ZAP70 Subverts Negative B-Cell Selection and Enables Oncogenic Signaling in Multiple B-Cell Malignancies
20190 citationsauthor #15
Differences in Self-Recognition between Secreted Antibody and Membrane-Bound B Cell Antigen Receptor
201919 citationsauthor #10
LGR5 Mediates Positive B-Cell Selection and is Critical for Survival of Normal and Transformed B Cells
20181 citationsauthor #14
Interleukin 7 receptor is associated with central nervous system infiltration 1 and relapse in pediatric B-cell precursor acute lymphoblastic leukemia
20180 citationsauthor #18
Chronic Lymphocytic Leukemia B Cells Display IgM and IgD Isotype-Restricted Features That Affect Association with Co-Receptors, BCR Signaling, and Leukemic B-Cell Growth In Vivo
20180 citationsauthor #11
CD79a Is Associated with Central Nervous System Infiltration of Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia
20181 citationsauthor #10
Association of CXCR4 with IgM and IgD BCR Isotypes: Role in B Cell Malignancies
20182 citationsauthor #8
PI3K induces B-cell development and regulates B cell identity
201851 citationsauthor #5
IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia.
201843 citationsauthor #16
Lgr5 Enables Positive B-Cell Selection and Tumor-Initiation in B-Cell Malignancies
20182 citationsauthor #12
Isotype Specific Assembly of B Cell Antigen Receptors and Synergism With Chemokine Receptor CXCR4
201814 citationsauthor #4
B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.
201898 citationsauthor #16
Abstract 4515: Lgr5 mediates positive B-cell selection and is critical for initiation and survival of B-cell malignancies
20180 citationsauthor #14
Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope
2018105 citationsauthor #9
PI3K-Mediated Blimp-1 Activation Controls B Cell Selection and Homeostasis
201829 citationsauthor #7
Abstract 368: B-lymphoid transcriptional repression of the pentose phosphate pathway reveals a unique therapeutic vulnerability of B cell malignancies
20180 citationsauthor #7
The BTG2-PRMT1 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex
201747 citationsauthor #11
Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia
2017112 citationsauthor #12
IgM and IgD Differential CLL BCRs Organization and Interaction with Co-Receptors before and during Ibrutinib Therapy
20171 citationsauthor #20
IgM and IgD Differential CLL BCRs Organization and Interaction with Co-Receptors before and during Ibrutinib Therapy
20171 citationsauthor #19
IgM and IgD Differential CLL BCRs Organization and Interaction with Co-Receptors before and during Ibrutinib Therapy
20171 citationsauthor #18
Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development
201736 citationsauthor #6
CXCR4 signaling and function require the expression of the IgD-class B-cell antigen receptor
201776 citationsauthor #3
Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development
20170 citationsauthor #6
Ig light chain gene rearrangement pre-B cell differentiation and the induction of Bruton's tyrosine kinase and SLP-65 regulate
20170 citationsauthor #1
Pathogen‐specific B‐cell receptors drive chronic lymphocytic leukemia by light‐chain‐dependent cross‐reaction with autoantigens
201717 citationsauthor #10
Lgr5 Functions As Negative Regulator of Wnt Signaling in B Cells and Is Critical for Self-Renewal of Normal and Transformed B Cells
20176 citationsauthor #11
Dangerous fusions: a path to cancer for arrested lymphoid progenitors
20171 citationsauthor #2
Control of B Cell Responsiveness by Isotype and Structural Elements of the Antigen Receptor.
201632 citationsauthor #3
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.
201668 citationsauthor #25
Primary Mediastinal Large B-Cell Lymphoma Exhibits Autonomous BCR Signaling and Responds to the Second Generation BTK Inhibitor Acalabrutinib
20162 citationsauthor #9
Abstract LB-012: Autonomous, antigen-independent B-cell receptor signalling as a novel pathogenetic mechanism in non-GCB DLBCL
20161 citationsauthor #14
Correction: Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia
20165 citationsauthor #22
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells
2016100 citationsauthor #16
Spleen Tyrosine Kinase Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia
201615 citationsauthor #10
Deficiency of secreted IgM antibodies causes increased plasma IgE levels that promote atherosclerosis
20160 citationsauthor #13
Antigen-Independent, Autonomous B-Cell Receptor Signaling As a Dominant Candidate Oncogenic Mechanism in ABC DLBCL
20161 citationsauthor #13
Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition
201668 citationsauthor #18
Erratum: Responsiveness of B cells is regulated by the hinge region of IgD
20156 citationsauthor #14
Chystallographic Evidence of Autologous Recognition By a Clonotypic B Cell Receptor in Chronic Lymphocytic Leukemia
20150 citationsauthor #10
Abstract 2075: Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia
20150 citationsauthor #18
SYK Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia
20151 citationsauthor #10
Tuning B cell responsiveness by antigen receptor isotype
20152 citationsauthor #1
Proliferation and Differentiation Programs of Developing B Cells
20153 citationsauthor #2
Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia
201589 citationsauthor #22
Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma.
201576 citationsauthor #16
B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation
2015120 citationsauthor #3
Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL.
201560 citationsauthor #20
Autoreactivity and the positive selection of B cells
201527 citationsauthor #2
Deletion of serine/arginine‐rich splicing factor 3 in hepatocytes predisposes to hepatocellular carcinoma in mice
2015103 citationsauthor #3
Activation loop phosphorylation regulates B‐Raf in vivo and transformation by B‐Raf mutants
201534 citationsauthor #16
Assembly and Function of the Precursor B-Cell Receptor.
201513 citationsauthor #3
Responsiveness of B cells is regulated by the hinge region of IgD
2015120 citationsauthor #14
Antibody repertoire diversification through VH gene replacement in mice cloned from an IgA plasma cell
201515 citationsauthor #6
A Conditional Knockout Mouse Model Reveals That Calponin-3 Is Dispensable for Early B Cell Development
201517 citationsauthor #4
Crystallographic evidence of autologous recognition by a clonotypic B cell receptor in chronic lymphocytic leukemia
20150 citationsauthor #11
Premature Terminal Differentiation Protects from Deregulated Lymphocyte Activation by ITK-Syk
201411 citationsauthor #11
The role of BCR isotype in B-cell development and activation.
201418 citationsauthor #2
Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR+ B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism
20140 citationsauthor #17
Inducible expression of hyperactive Syk in B cells activates Blimp-1-dependent terminal differentiation
201424 citationsauthor #4
Harnessing Negative B Cell Selection to Overcome Drug-Resistance in Acute Lymphoblastic Leukemia
20140 citationsauthor #13
Cancer Biology and Signal Transduction PIM Kinases Are Essential for Chronic Lymphocytic Leukemia Cell Survival ( PIM 2 / 3 ) and CXCR 4-Mediated Microenvironmental Interactions ( PIM 1 )
20140 citationsauthor #10
Pre-BCR Signaling Activity Predicts Sensitivity To Syk Kinase Inhibition In B Cell Acute Lymphoblastic Leukemia (B-ALL)
20130 citationsauthor #12

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