K. Wilcox

Glutamate dynamics in the dorsolateral striatum of rats with goal-directed and habitual cocaine-seeking behavior
20230 citationsauthor #5
Closed-loop neurostimulation for epilepsy leads to improved outcomes when stimulation episodes are delivered during periods with less epileptiform activity
20223 citationsauthor #8
SEIZURE ONSET AND OFFSET DYNAMICS IN A TEMPORAL LOBE EPILEPSY MOUSE MODEL OVER 90 DAYS
20220 citationsauthor #5
A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus.
20227 citationsauthor #5
Evaluating the efficacy of prototype antiseizure drugs using a preclinical pharmacokinetic approach
202210 citationsauthor #4
EFFECTS OF TREM-1 EXPRESSION ON ACUTE PHASE SEIZURES IN A MOUSE MODEL OF VIRAL-INDUCED EPILEPSY
20220 citationsauthor #3
Evaluation of spontaneous seizure activity, sex-dependent differences, behavioral comorbidities, and alterations in CA1 neuron firing properties in a mouse model of Dravet Syndrome
20212 citationsauthor #7
Response: Usefulness of the post‐kainate spontaneous recurrent seizure model for screening for antiseizure and for neuroprotective effects
20211 citationsauthor #4
Antiepileptogenesis and disease modification: Progress, challenges, and the path forward—Report of the Preclinical Working Group of the 2018 NINDS‐sponsored antiepileptogenesis and disease modification workshop
202136 citationsauthor #13
Screening of prototype antiseizure and anti‐inflammatory compounds in the Theiler's murine encephalomyelitis virus model of epilepsy
202123 citationsauthor #7
Inflammation Unleashed in Viral-Induced Epileptogenesis
202115 citationsauthor #4
Identification of clinically relevant biomarkers of epileptogenesis — a strategic roadmap
202177 citationsauthor #13
Ultrastructural and functional changes at the tripartite synapse during epileptogenesis in a model of temporal lobe epilepsy.
202027 citationsauthor #6
Development of an antiepileptogenesis drug screening platform: Effects of everolimus and phenobarbital
202018 citationsauthor #6
Reactivity and increased proliferation of NG2 cells following central nervous system infection with Theiler’s murine encephalomyelitis virus
20200 citationsauthor #3
Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program
202034 citationsauthor #10
Discovery of the first Vitamin K analog as a potential treatment of pharmacoresistant seizures.
202020 citationsauthor #9
Reactivity and increased proliferation of NG2 cells following central nervous system infection with Theiler’s murine encephalomyelitis virus
202020 citationsauthor #3
Accurate detection of spontaneous seizures using a generalized linear model with external validation
20207 citationsauthor #12
Evaluation of subchronic administration of antiseizure drugs in spontaneously seizing rats
202022 citationsauthor #7
Spontaneous recurrent seizures in an intra-amygdala kainate microinjection model of temporal lobe epilepsy are differentially sensitive to antiseizure drugs
202023 citationsauthor #9
Cannabidiol reduces seizures following CNS infection with Theiler's murine encephalomyelitis virus
201927 citationsauthor #4
Mechanisms of Epilepsy and Neuronal Synchronization Gordon Research Conference Power Hour Summary
20190 citationsauthor #2
The Current Approach of the Epilepsy Therapy Screening Program Contract Site for Identifying Improved Therapies for the Treatment of Pharmacoresistant Seizures in Epilepsy.
201971 citationsauthor #1
Evaluation of antiseizure drug efficacy and tolerability in the rat lamotrigine‐resistant amygdala kindling model
201928 citationsauthor #6
Conditional Knock-out of mGluR5 from Astrocytes during Epilepsy Development Impairs High-Frequency Glutamate Uptake
201852 citationsauthor #4
Epilepsy as a network disorder: What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research?
201830 citationsauthor #15
Recurrent epileptiform discharges in the medial entorhinal cortex of kainate‐treated rats are differentially sensitive to antiseizure drugs
201826 citationsauthor #7
Development and pharmacologic characterization of the rat 6 Hz model of partial seizures
201774 citationsauthor #7
Validation of a Preclinical Drug Screening Platform for Pharmacoresistant Epilepsy
201763 citationsauthor #16
Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP)
2017109 citationsauthor #5
Validation of a Preclinical Drug Screening Platform for Pharmacoresistant Epilepsy
20170 citationsauthor #16
Preclinical Comparison of Mechanistically Different Antiseizure, Antinociceptive, and/or Antidepressant Drugs in a Battery of Rodent Models of Nociceptive and Neuropathic Pain
201721 citationsauthor #12
Novel Targets for Developing Antiseizure and, Potentially, Antiepileptogenic Drugs
201718 citationsauthor #2
Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP)
20170 citationsauthor #5
Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy
201794 citationsauthor #13
Chapter 46 – Postinfectious Epilepsy
20172 citationsauthor #2
Corneal kindled C57BL/6 mice exhibit saturated dentate gyrus long-term potentiation and associated memory deficits in the absence of overt neuron loss.
201722 citationsauthor #6
NBQX, a highly selective competitive antagonist of AMPA and KA ionotropic glutamate receptors, increases seizures and mortality following picornavirus infection.
201629 citationsauthor #4
Repeated low-dose kainate administration in C57BL/6J mice produces temporal lobe epilepsy pathology but infrequent spontaneous seizures.
201646 citationsauthor #10
Acute treatment with minocycline, but not valproic acid, improves long‐term behavioral outcomes in the Theiler's virus model of temporal lobe epilepsy
201650 citationsauthor #6
sec-Butylpropylacetamide (SPD) has antimigraine properties
201615 citationsauthor #6
SCN8A encephalopathy: Research progress and prospects
2016123 citationsauthor #17
Neuronal Injury, Gliosis, and Glial Proliferation in Two Models of Temporal Lobe Epilepsy
201684 citationsauthor #5
Striatumin Ventromedial Versus Dorsolateral Evidence for Functionally Distinct Synaptic NMDA
20150 citationsauthor #2
Oxidative stress in murine Theiler's virus-induced temporal lobe epilepsy.
201537 citationsauthor #3
Altered structure and function of astrocytes following status epilepticus.
201528 citationsauthor #1
Decrease in CA3 inhibitory network activity during Theiler's virus encephalitis.
201512 citationsauthor #4
Evaluating an Etiologically Relevant Platform for Therapy Development for Temporal Lobe Epilepsy: Effects of Carbamazepine and Valproic Acid on Acute Seizures and Chronic Behavioral Comorbidities in the Theiler’s Murine Encephalomyelitis Virus Mouse Model
201548 citationsauthor #6
Imaging activity in astrocytes and neurons with genetically encoded calcium indicators following in utero electroporation
201536 citationsauthor #3
NeuronsSpontaneous EPSCs in Cultured Cortical - Effect of Conantokin G on NMDA Receptor
20150 citationsauthor #2
Impaired cognitive ability and anxiety-like behavior following acute seizures in the Theiler's virus model of temporal lobe epilepsy.
201465 citationsauthor #9
Antiseizure drugs differentially modulate theta‐burst induced long‐term potentiation in C57BL/6 mice
201422 citationsauthor #4
Could Astrocytes be Used to Beat Epilepsy? Experiments in dnSNARE Mice Drum up New Hope
20140 citationsauthor #2
The challenge and promise of anti-epileptic therapy development in animal models.
2014105 citationsauthor #9
Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse.
2014136 citationsauthor #16
Acute seizures during viral encephalitis are due to IL-6-producing macrophages
20140 citationsauthor #4
Does brain inflammation mediate pathological outcomes in epilepsy?
201470 citationsauthor #1
Issues related to development of new antiseizure treatments
201380 citationsauthor #1
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
201321 citationsauthor #8
Rapid loss of efficacy to the antiseizure drugs lamotrigine and carbamazepine: A novel experimental model of pharmacoresistant epilepsy
201341 citationsauthor #3
Contributions of astrocytes to epileptogenesis following status epilepticus: opportunities for preventive therapy?
201343 citationsauthor #5
A new derivative of valproic acid amide possesses a broad‐spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage
201263 citationsauthor #6
Altered Learning and Arc-Regulated Consolidation of Learning in Striatum by Methamphetamine-Induced Neurotoxicity
201226 citationsauthor #3
The activity within the CA3 excitatory network during Theiler's virus encephalitis is distinct from that observed during chronic epilepsy
201220 citationsauthor #6
Figure 1, The potassium channel gene family and epilepsy channelopathies
20120 citationsauthor #2
The activity within the CA3 excitatory network during Theiler's virus encephalitis is distinct from that observed during chronic epilepsy
20121 citationsauthor #6
Interleukin-6, Produced by Resident Cells of the Central Nervous System and Infiltrating Cells, Contributes to the Development of Seizures following Viral Infection
2011103 citationsauthor #3
Lack of Correlation of Central Nervous System Inflammation and Neuropathology with the Development of Seizures following Acute Virus Infection
201130 citationsauthor #3
Targeted Path Scanning: An Emerging Method for Recording Fast Changing Network Dynamics across Large Distances
20115 citationsauthor #4
Once initiated, viral encephalitis-induced seizures are consistent no matter the treatment or lack of interleukin-6
201124 citationsauthor #3
Topiramate modulation of β(1)- and β(3)-homomeric GABA(A) receptors.
201119 citationsauthor #2
CGX-1007 prevents excitotoxic cell death via actions at multiple types of NMDA receptors.
201119 citationsauthor #5
cAMP-dependent protein kinase A activity modulates topiramate potentiation of GABA(A) receptors.
20117 citationsauthor #3
Chapter 53 Potassium Channelopathies of Epilepsy
20110 citationsauthor #2
Discovery of antiepileptic drugs
2011161 citationsauthor #2
Pharmacogenetics of AED Development
20100 citationsauthor #4
Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus.
2010104 citationsauthor #3
Role for Complement in the Development of Seizures following Acute Viral Infection
201047 citationsauthor #3
Differential Contribution of Kainate Receptors to EPSCs in Superficial Layer Neurons of the Rat Medial Entorhinal Cortex
20101 citationsauthor #3
ADENOSINE PREVENTS KINDLED SEIZURES—AN EFFECT AS SMOOTH AS SILK
20101 citationsauthor #9
Mechanisms of action of antiepileptic drugs.
201098 citationsauthor #3
Innate but not adaptive immune responses contribute to behavioral seizures following viral infection
2010118 citationsauthor #3
Potassium channelopathies of epilepsy
201031 citationsauthor #2
Development of Postinfection Epilepsy After Theiler's Virus Infection of C57BL/6 Mice
2010112 citationsauthor #2
Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions
200944 citationsauthor #7
The Role of Short Term Synaptic Plasticity in the Development and Spread of Seizures
20090 citationsauthor #1
PLASTICITY | The Role of Short Term Synaptic Plasticity in Development and Spread of Seizures
20090 citationsauthor #1
Theiler’s virus infection chronically alters seizure susceptibility
200980 citationsauthor #2
Mouse Models of Benign Familial Neonatal Convulsions (BFNC): Mutations in KCNQ (Kv7) Genes
20092 citationsauthor #5
FULL-LENGTH ORIGINAL RESEARCH Seizures following picornavirus infection
20080 citationsauthor #4
Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC).
200826 citationsauthor #10
Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization
2008148 citationsauthor #9
Differences in excitatory transmission between thalamic and cortical afferents to single spiny efferent neurons of rat dorsal striatum
200849 citationsauthor #3
In vivo pharmacological effects of JZP-4, a novel anticonvulsant, in models for anticonvulsant, antimania and antidepressant activity.
200822 citationsauthor #4
Seizures following picornavirus infection
2008122 citationsauthor #5
A rat brain slice preparation for characterizing both thalamostriatal and corticostriatal afferents.
200785 citationsauthor #4
Phenytoin- and carbamazepine-resistant spontaneous bursting in rat entorhinal cortex is blocked by retigabine in vitro.
200732 citationsauthor #5
CHAPTER 44 – Therapeutic Assays for the Identification and Characterization of Antiepileptic and Antiepileptogenic Drugs
200640 citationsauthor #4
Effect of Conantokin G on NMDA receptor-mediated spontaneous EPSCs in cultured cortical neurons.
200614 citationsauthor #3

PROFILE

PAPERS

TIMELINE

COAUTHOR MAP

CONCEPT FOOTPRINT