Tomato PYR/PYL/RCAR abscisic acid receptors show high expression in root, differential sensitivity to the abscisic acid agonist quinabactin, and the capability to enhance plant drought resistance

Summary Chemical and transgenic approaches can activate ABA signalling via crop PYR/PYL ABA receptors; quinabactin can selectively activate tomato ABA receptors, and overexpression of monomeric-type receptors confers enhanced plant drought resistance.

• Publication year

  2014

• Venue

  Journal of Experimental Botany

• Publication date

  2014-05-26

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1093/jxb/eru219PMID 24863435PMCID 4112642
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Overexpression of PYL5 in rice enhances drought tolerance, inhibits growth, and modulates gene expression

  2014cited by this paper
• ABA control of plant macroelement membrane transport systems in response to water deficit and high salinity.

  2014cited by this paper
• Endodermal ABA Signaling Promotes Lateral Root Quiescence during Salt Stress in Arabidopsis Seedlings[C][W]

  2013cited by this paper
• Structural Insights into the Abscisic Acid Stereospecificity by the ABA Receptors PYR/PYL/RCAR

  2013influential reference
• Abscisic Acid Synthesis and Response

  2013influential reference
• Comparative transcriptome analysis of tomato (Solanum lycopersicum) in response to exogenous abscisic acid

  2013cited by this paper
• The PYL4 A194T Mutant Uncovers a Key Role of PYR1-LIKE4/PROTEIN PHOSPHATASE 2CA Interaction for Abscisic Acid Signaling and Plant Drought Resistance1[C][W][OPEN]

  2013cited by this paper
• The tomato SlSHINE3 transcription factor regulates fruit cuticle formation and epidermal patterning.

  2013cited by this paper
• Interactions between soybean ABA receptors and type 2C protein phosphatases

  2013cited by this paper
• An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants

  2013influential reference
• ABI1 and PP2CA Phosphatases Are Negative Regulators of Snf1-Related Protein Kinase1 Signaling in Arabidopsis[C][W]

  2013cited by this paper
• Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance

  2013influential reference
• ABA transport and transporters.

  2013cited by this paper
• A rice orthologue of the ABA receptor, OsPYL/RCAR5, is a positive regulator of the ABA signal transduction pathway in seed germination and early seedling growth.

  2012cited by this paper
• PYRABACTIN RESISTANCE1-LIKE8 Plays an Important Role for the Regulation of Abscisic Acid Signaling in Root1[C][W][OA]

  2012cited by this paper
• Complex structures of the abscisic acid receptor PYL3/RCAR13 reveal a unique regulatory mechanism.

  2012cited by this paper
• Uniform ripening Encodes a Golden 2-like Transcription Factor Regulating Tomato Fruit Chloroplast Development

  2012cited by this paper
• The tomato genome sequence provides insights into fleshy fruit evolution

  2012cited by this paper
• Suppression of 9-cis-Epoxycarotenoid Dioxygenase, Which Encodes a Key Enzyme in Abscisic Acid Biosynthesis, Alters Fruit Texture in Transgenic Tomato1[W][OA]

  2012cited by this paper
• The Citrus ABA signalosome: identification and transcriptional regulation during sweet orange fruit ripening and leaf dehydration

  2012cited by this paper
• Characterization of potential ABA receptors in Vitis vinifera

  2012cited by this paper
• The ABA signal transduction mechanism in commercial crops: learning from Arabidopsis

  2012cited by this paper
• Physiological Genomics of Response to Soil Drying in Diverse Arabidopsis Accessions[W][OA]

  2012cited by this paper
• Availability of Micro-Tom mutant library combined with TILLING in molecular breeding of tomato fruit shelf-life

  2012cited by this paper
• Unique Drought Resistance Functions of the Highly ABA-Induced Clade A Protein Phosphatase 2Cs1[W][OA]

  2012cited by this paper
• Evolution of abscisic acid synthesis and signaling mechanisms.

  2011cited by this paper
• Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation

  2011cited by this paper
• Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco

  2011cited by this paper
• Transcriptional regulation of SlPYL, SlPP2C, and SlSnRK2 gene families encoding ABA signal core components during tomato fruit development and drought stress

  2011cited by this paper
• Selective Inhibition of Clade A Phosphatases Type 2C by PYR/PYL/RCAR Abscisic Acid Receptors1[C][W]

  2011influential reference
• Modulation of Abscisic Acid Signaling in Vivo by an Engineered Receptor-Insensitive Protein Phosphatase Type 2C Allele1[C][W]

  2011influential reference
• The Plant Cuticle Is Required for Osmotic Stress Regulation of Abscisic Acid Biosynthesis and Osmotic Stress Tolerance in Arabidopsis[W]

  2011cited by this paper
• A thermodynamic switch modulates abscisic acid receptor sensitivity

  2011influential reference
• The molecular basis of ABA-independent inhibition of PP2Cs by a subclass of PYL proteins.

  2011influential reference
• FaPYR1 is involved in strawberry fruit ripening.

  2011cited by this paper
• Abscisic acid: emergence of a core signaling network.

  2010cited by this paper
• The abscisic acid receptor PYR1 in complex with abscisic acid

  2009influential reference
• Protein Phosphatases 2C Regulate the Activation of the Snf1-Related Kinase OST1 by Abscisic Acid in Arabidopsis[W]

  2009cited by this paper
• A Gate-Latch-Lock Mechanism for Hormone Signaling by Abscisic Acid Receptors

  2009cited by this paper
• Structural basis of abscisic acid signalling

  2009influential reference
• The Nuclear Interactor PYL8/RCAR3 of Fagus sylvatica FsPP2C1 Is a Positive Regulator of Abscisic Acid Signaling in Seeds and Stress1[C][W][OA]

  2009cited by this paper
• Structural Mechanism of Abscisic Acid Binding and Signaling by Dimeric PYR1

  2009cited by this paper
• PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis

  2009cited by this paper
• Type 2C protein phosphatases directly regulate abscisic acid-activated protein kinases in Arabidopsis

  2009cited by this paper
• Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.

  2009cited by this paper
• Regulators of PP2C Phosphatase Activity Function as Abscisic Acid Sensors

  2009influential reference
• Structural insights into the mechanism of abscisic acid signaling by PYL proteins

  2009cited by this paper
• Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins

  2009cited by this paper
• The role of ABA in triggering ethylene biosynthesis and ripening of tomato fruit

  2009cited by this paper
• HAB1–SWI3B Interaction Reveals a Link between Abscisic Acid Signaling and Putative SWI/SNF Chromatin-Remodeling Complexes in Arabidopsis[C][W]

  2008cited by this paper
• The plant cell

  2007cited by this paper
• Enhancement of Abscisic Acid Sensitivity and Reduction of Water Consumption in Arabidopsis by Combined Inactivation of the Protein Phosphatases Type 2C ABI1 and HAB11[W]

  2006influential reference
• Methods and concepts in quantifying resistance to drought, salt and freezing, abiotic stresses that affect plant water status.

  2006cited by this paper
• Journal of Experimental Botany, Page 1 of 10

  2004cited by this paper
• Root growth maintenance during water deficits: physiology to functional genomics.

  2004cited by this paper
• Analysis of an activated ABI5 allele using a new selection method for transgenic Arabidopsis seeds

  2004cited by this paper
• Summaries of Affymetrix GeneChip probe level data.

  2003cited by this paper
• ABA, ethylene and the control of shoot and root growth under water stress.

  2002cited by this paper
• An investigation of the substrate specificity of protein phosphatase 2C using synthetic peptide substrates; comparison with protein phosphatase 2A.

  1990cited by this paper
• A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay.

  1988cited by this paper
• Efficient octopine Ti plasmid-derived vectors for Agrobacterium- mediated gene transfer to plants

  1985cited by this paper

• MdWRKY75 regulates MdCAR4-mediated ABA receptor turnover to enhance drought resistance in apple.

  2026cites this paper
• Deciphering ABA/PYL gene family in flax: evolutionary analysis, and abiotic stress response

  2025cites this paper
• Genome-wide identification of the PYL gene family and functional validation of SiPYL3 in foxtail millet (Setaria italica).

  2025cites this paper
• Elucidating the role of pyrabactin-like receptors of finger millet under drought and salinity stress: an insight into in silico, machine learning and molecular approaches

  2025cites this paper
• The role of stress hormones in regulating tomato resilience and metabolism.

  2025cites this paper
• Transcriptional Profiling to Assess the Effects of Biological Stimulant Atlanticell Micomix on Tomato Seedlings Under Salt Stress

  2025cites this paper
• Genome-Wide Characterization of the ABA Receptor Pyrabactin Resistance 1-like (PYL) Gene Family in Strawberry and Functional Assessment of FaPYL3 and FaPYL4 in Fruit Ripening

  2025cites this paper
• Abscisic Acid Enhances Ex Vitro Acclimatization Performance in Hop (Humulus lupulus L.)

  2025cites this paper
• Reduction of the geomagnetic field to hypomagnetic field modulates tomato (Solanum lycopersicum L. cv Microtom) gene expression and metabolomics during plant development.

  2025cites this paper
• Genome-Wide Characterization of 9-Cis-Epoxycarotenoid Dioxygenase Genes in Luffa Identifies LcNCED2 as Being Associated with ABA Levels During Seed Germination

  2025cites this paper
• ZmHB53, a Maize Homeodomain‐Leucine Zipper I Transcription Factor Family Gene, Contributes to Abscisic Acid Sensitivity and Confers Seedling Drought Tolerance by Promoting the Activity of ZmPYL4

  2025cites this paper
• Overexpression of SlPYR1 and SlPYL8 confers ABA hypersensitivity, plant dwarfing, and delayed senescence in tomato

  2025cites this paper
• Structural insight into ABA receptor agonists reveals critical features to optimize and design a broad-spectrum activator of ABA signaling.

  2025cites this paper
• Synergistic Enhancement of Plant Drought Tolerance by PYL and ABA—A Review

  2025cites this paper
• The responses and adaptations of rice (Oryza sativa L.) to drought stress: A review

  2025cites this paper
• Genome-Wide Identification of the StPYL Gene Family and Analysis of the Functional Role of StPYL9a-like in Salt Tolerance in Potato (Solanum tuberosum L.)

  2025cites this paper
• Characterization of the ABA receptor PYL gene family and identification of DoPYL1-interacting proteins in Dendrobium officinale

  2025cites this paper
• TaPYR10 Coordinates Abscisic Acid Sensing and Downstream Gene Activation to Deliver Drought Resilience and Yield Benefits in Wheat

  2025cites this paper
• Plant immunity to insect herbivores: mechanisms, interactions, and innovations for sustainable pest management

  2025cites this paper
• Silicon nanoparticles improved the osmolyte production, antioxidant defense system, and phytohormone regulation in Elymus sibiricus (L.) under drought and salt stress

  2024cites this paper
• Overexpression of the Potato StPYL20 Gene Enhances Drought Resistance and Root Development in Transgenic Plants

  2024cites this paper
• Unlocking Nature's Stress Buster: Abscisic Acid's Crucial Role in Defending Plants Against Abiotic Stress

  2024cites this paper
• Chemical activation of ABA signaling in grapevine through the iSB09 and AMF4 ABA receptor agonists enhances water use efficiency

  2024cites this paper
• Genome-wide characterization of pyrabactin resistance 1-like (PYL) family genes revealed AhPYL6 confer the resistance to Ralstonia solanacearum in peanut.

  2024cites this paper
• From Regulation to Application: The Role of Abscisic Acid in Seed and Fruit Development and Agronomic Production Strategies

  2024cites this paper
• Multifunctional Transcription Factor YABBY6 Regulates Morphogenesis, Drought and Cold Stress Responses in Rice

  2024cites this paper
• Wheat TaPYL9‐involved signalling pathway impacts plant drought response through regulating distinct osmotic stress‐associated physiological indices

  2024cites this paper
• The Abscisic Acid Receptor Gene StPYL8-like from Solanum tuberosum Confers Tolerance to Drought Stress in Transgenic Plants

  2024cites this paper
• Overexpression of Potato PYL16 Gene in Tobacco Enhances the Transgenic Plant Tolerance to Drought Stress

  2024cites this paper
• Genome-wide analysis of the PYL-PP2C-SnRK2s family in the ABA signaling pathway of pitaya reveals its expression profiles under canker disease stress

  2024cites this paper
• Genome-wide identification, abiotic stress, and expression analysis of PYL family in Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn.) during grain development

  2024cites this paper
• GhWRKY1bD improves drought tolerance by co-regulation of ABA, ROS, and proline homeostasis in cotton (Gossypium hirsutum)

  2024cites this paper
• Genome-Wide Analysis of the PYL Gene Family in Betula platyphylla and Its Responses to Abiotic Stresses

  2024cites this paper
• ABA-receptor agonist iSB09 decreases soil water consumption and increases tomato CO2 assimilation and water use efficiency under drought stress

  2024cites this paper
• Construction of a Membrane Yeast Two-Hybrid Library and Screening of MsPYR1-Like Interacting Proteins in Malus sieversii

  2024cites this paper
• Transcriptome and metabolome analyses reveal the regulatory role of MdPYL9 in drought resistance in apple

  2024cites this paper
• Wheat kinase TaSnRK2.4 forms a functional module with phosphatase TaPP2C01 and transcription factor TaABF2 to regulate drought response

  2024cites this paper
• Genome-Wide Identification of PYL/RCAR ABA Receptors and Functional Analysis of LbPYL10 in Heat Tolerance in Goji (Lycium barbarum)

  2024cites this paper
• Genome-wide investigation of the PYL genes in Acer palmatum and their role in freezing tolerance

  2024cites this paper
• Genome-wide identification of PYL/PYR-PP2C (A)-SnRK2 genes in Eutrema and their co-expression analysis in response to ABA and abiotic stresses.

  2023cites this paper
• Signalling mechanisms and agricultural applications of (Z)-3-hexenyl butyrate-mediated stomatal closure

  2023cites this paper
• ABA signaling branches out: emerging ABA-related signaling functions in Solanum tuberosum

  2023cites this paper
• CePP2C19 confers tolerance to drought by regulating the ABA sensitivity in Cyperus esculentus

  2023cites this paper
• A metabolome and transcriptome survey to tap the dynamics of fruit prolonged shelf-life and improved quality within Greek tomato germplasm

  2023cites this paper
• Biostimulant activity of Galaxaura rugosa seaweed extracts against water deficit stress in tomato seedlings involves activation of ABA signaling

  2023cites this paper
• Signaling mechanisms and agricultural applications of (Z)-3-Hexenyl Butyrate-mediated stomatal closure

  2023cites this paper
• PYL Family Genes from Liriodendron chinense Positively Respond to Multiple Stresses

  2023cites this paper
• GhPYL9-5D and GhPYR1-3 A positively regulate Arabidopsis and cotton responses to ABA, drought, high salinity and osmotic stress

  2023cites this paper
• Abscisic acid mimic-fluorine derivative 4 alleviates water deficit stress by regulating ABA-responsive genes, proline accumulation, CO2 assimilation, water use efficiency and better nutrient uptake in tomato plants

  2023cites this paper
• Transcriptome analysis reveals the effects of hydrogen gas on NaCl stress in purslane roots

  2023cites this paper
• Abscisic Acid Synthesis and Signaling during the Ripening of Raspberry (Rubus idaeus ‘Heritage’) Fruit

  2023cites this paper
• Structure-guided engineering of a receptor-agonist pair for inducible activation of the ABA adaptive response to drought

  2023cites this paper
• Traces of Introgression from cAus into Tropical Japonica Observed in African Upland Rice Varieties

  2023cites this paper
• Identification of Pyrabactin resistance 1-like (PYL) genes in Brachypodium distachyon and functional characterization of BdPYL5.

  2023cites this paper
• How Changes in ABA Accumulation and Signaling Influence Tomato Drought Responses and Reproductive Development

  2023cites this paper
• Characterization and expression analysis of key abscisic acid signal transduction genes during kiwifruit development

  2023cites this paper
• Genome-wide identification of the PYL gene family and expression of PYL genes under abiotic stresses in Chinese cabbage

  2022cites this paper
• Jasmonic acid enhances osmotic stress responses by MYC2-mediated inhibition of protein phosphatase 2C1 and response regulators 26 transcription factor in tomato.

  2022cites this paper
• Amino acid motifs for the identification of novel protein interactants

  2022cites this paper
• Modifications of Phytohormone Metabolism Aimed at Stimulation of Plant Growth, Improving Their Productivity and Tolerance to Abiotic and Biotic Stress Factors

  2022cites this paper
• Transcriptome analysis of response strategy in Hemerocallis fulva under drought stress

  2022cites this paper
• PePYL4 enhances drought tolerance by modulating water use efficiency and ROS scavenging in Populus.

  2022cites this paper
• TaPYL4, an ABA receptor gene of wheat, positively regulates plant drought adaptation through modulating the osmotic stress-associated processes

  2022cites this paper
• Genome-Wide Identification of the PYL Gene Family in Chenopodium quinoa: From Genes to Protein 3D Structure Analysis

  2022cites this paper
• Co-silencing of ABA receptors (SlRCAR) reveals interactions between ABA and ethylene signaling during tomato fruit ripening

  2022cites this paper
• Structure-Based Modulation of the Ligand Sensitivity of a Tomato Dimeric Abscisic Acid Receptor Through a Glu to Asp Mutation in the Latch Loop

  2022cites this paper
• Genome-wide identification, characterization and expression analysis of the ABA receptor PYL gene family in response to ABA, photoperiod, and chilling in vegetative buds of Liriodendron chinense

  2022cites this paper
• GhHAI2, GhAHG3, and GhABI2 Negatively Regulate Osmotic Stress Tolerance via ABA-Dependent Pathway in Cotton (Gossypium hirsutum L.)

  2022cites this paper
• Abscisic Acid: Role in Fruit Development and Ripening

  2022cites this paper
• Brassinosteroid-Insensitive 1-Associated Receptor Kinase 1 Modulates Abscisic Acid Signaling by Inducing PYR1 Monomerization and Association With ABI1 in Arabidopsis

  2022cites this paper
• Genome-wide identification and comparative analysis of the PYL gene family in eight Rosaceae species and expression analysis of seeds germination in pear

  2022cites this paper
• PYL1- and PYL8-like ABA Receptors of Nicotiana benthamiana Play a Key Role in ABA Response in Seed and Vegetative Tissue

  2022cites this paper
• Mechanisms of Abscisic Acid-Mediated Drought Stress Responses in Plants

  2022cites this paper
• Genome-wide identification and expression analysis of the cucumber PYL gene family

  2022cites this paper
• Increased abscisic acid sensitivity and drought tolerance of Arabidopsis by overexpression of poplar abscisic acid receptors

  2022cites this paper
• Increased Abscisic Acid Sensitivity And Drought Stress By Overexpression of Abscisic Acid Receptors In Arabidopsis Thaliana

  2021cites this paper
• Expression and processing of polycistronic artificial microRNAs and trans-acting siRNAs in Solanum lycopersicum and Nicotiana benthamiana

  2021cites this paper
• The wheat ABA receptor gene TaPYL1‐1B contributes to drought tolerance and grain yield by increasing water‐use efficiency

  2021cites this paper
• The ABA receptor gene MdPYL9 confers tolerance to drought stress in transgenic apple (Malus domestica)

  2021cites this paper
• Hormone mediated cell signaling in plants under changing environmental stress

  2021cites this paper
• An Update on Crop ABA Receptors

  2021influential citation
• Roles of Glutathione in Mediating Abscisic Acid Signaling and Its Regulation of Seed Dormancy and Drought Tolerance

  2021cites this paper
• Virus-induced gene silencing of SlPYL4 decreases the drought tolerance of tomato

  2021cites this paper
• Genome-wide identification of ABA receptor PYL/RCAR gene family and their response to cold stress in Medicago sativa L

  2021cites this paper
• Effect of Soil Water Deficits on Plant–Water Relationship: A Review

  2021cites this paper
• Cloning and expression analyses of a Pyrabactin Resistance 1 (PYR1) gene from Magnolia sieboldii K. Koch

  2021cites this paper
• Integration of mRNA and miRNA analysis reveals the molecular mechanism of potato (Solanum tuberosum L.) response to alkali stress.

  2021cites this paper
• Signaling in the Tomato Immunity against Fusarium oxysporum

  2021cites this paper
• The intricacy of silicon, plant growth regulators and other signaling molecules for abiotic stress tolerance: An entrancing crosstalk between stress alleviators.

  2021cites this paper
• Identification of ABA-Mediated Genetic and Metabolic Responses to Soil Flooding in Tomato (Solanum lycopersicum L. Mill)

  2021cites this paper
• Genome-wide identification of abscisic acid (ABA) receptor pyrabactin resistance 1-like protein (PYL) family members and expression analysis of PYL genes in response to different concentrations of ABA stress in Glycyrrhiza uralensis.

  2020cites this paper
• Grapevine ABA receptor VvPYL1 regulates root hair development in Transgenic Arabidopsis.

  2020cites this paper
• Salinity and water deficit

  2020cites this paper
• Overexpression of a sour jujube gene ZjPYR1, encoding a putative abscisic acid receptor, increases sensitivity of the stomata and roots to ABA in Arabidopsis thaliana.

  2020cites this paper
• Carbohydrate, Phytohormone, and Associated Transcriptome Changes during Storage Root Formation in Alligatorweed (Alternanthera philoxeroides)

  2020cites this paper
• Design of potent ABA receptor antagonists based on a conformational restriction approach.

  2020cites this paper
• Evolution of Abscisic Acid Signaling Module and Its Perception

  2020cites this paper
• The Role of ABA in Plant Immunity is Mediated through the PYR1 Receptor

  2020cites this paper
• Genome-Wide Identification of the ABA Receptors Genes and Their Response to Abiotic Stress in Apple

  2020cites this paper
• Early Molecular Responses of Tomato to Combined Moderate Water Stress and Tomato Red Spider Mite Tetranychus evansi Attack

  2020cites this paper