GABAergic neurons and GABA(A)-receptors in temporal lobe epilepsy.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Neurochemistry International

• Publication date

  1999-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0197-0186(99)00040-6PMID 10397372
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy.

  1999cited by this paper
• GABA release and uptake measured in crude synaptosomes from Genetic Absence Epilepsy Rats from Strasbourg (GAERS).

  1999cited by this paper
• The GABA-A receptor gene family: new targets for therapeutic intervention.

  1999cited by this paper
• Structure and subunit composition of GABA(A) receptors.

  1999cited by this paper
• Synaptic activation of kainate receptors on hippocampal interneurons

  1998cited by this paper
• Selective changes in single cell GABAA receptor subunit expression and function in temporal lobe epilepsy

  1998cited by this paper
• GluR5 kainate receptor activation in interneurons increases tonic inhibition of pyramidal cells

  1998cited by this paper
• Increased number of synaptic GABAA receptors underlies potentiation at hippocampal inhibitory synapses

  1998cited by this paper
• Synapse‐specific localization of NMDA and GABAA receptor subunits revealed by antigen‐retrieval immunohistochemistry

  1998cited by this paper
• Severe, Early and Selective Loss of a Subpopulation of GABAergic Inhibitory Neurons in Experimental Transmissible Spongiform Encephalopathies

  1998cited by this paper
• Differential epilepsy-associated alterations in postsynaptic GABA(A) receptor function in dentate granule and CA1 neurons.

  1997cited by this paper
• Instantaneous Perturbation of Dentate Interneuronal Networks by a Pressure Wave-Transient Delivered to the Neocortex

  1997cited by this paper
• Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats.

  1997cited by this paper
• GABA and Epileptogenesis

  1997cited by this paper
• GABA(A) receptor subunits in the rat hippocampus II: altered distribution in kainic acid-induced temporal lobe epilepsy.

  1997cited by this paper
• Progressive loss of glutamic acid decarboxylase, parvalbumin, and calbindin D28K immunoreactive neurons in the cerebral cortex and hippocampus of adult rat with experimental hydrocephalus

  1997cited by this paper
• Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate‐treated rats

  1997cited by this paper
• Progressive loss of glutamic acid decarboxylase, parvalbumin, and calbindin D28K immunoreactive neurons in the cerebral cortex and hippocampus of adult rat with experimental hydrocephalus.

  1996cited by this paper
• Short increase of BDNF messenger RNA triggers kainic acid-induced neuronal hypertrophy in adult mice.

  1996cited by this paper
• Laminar compartmentalization of GABAA-receptor subtypes in the spinal cord: an immunohistochemical study

  1996cited by this paper
• AMPA receptors in the rat and primate hippocampus: a possible absence of GluR2/3 subunits in most interneurons.

  1996cited by this paper
• Zinc-Induced Collapse of Augmented Inhibition by GABA in a Temporal Lobe Epilepsy Model

  1996cited by this paper
• Ca(2+)‐permeable AMPA and NMDA receptor channels in basket cells of rat hippocampal dentate gyrus.

  1995cited by this paper
• GABAA‐receptor heterogeneity in the adult rat brain: Differential regional and cellular distribution of seven major subunits

  1995cited by this paper
• Alpha subunits influence Zn block of gamma 2 containing GABAA receptor currents.

  1995cited by this paper
• α subunits influence Zn block of γ2 containing GABAA receptor currents

  1995cited by this paper
• Morphogenetic effect of kainate on adult hippocampal neurons associated with a prolonged expression of brain-derived neurotrophic factor.

  1995cited by this paper
• Hippocampal GABA transporter function in temporal-lobe epilepsy

  1995cited by this paper
• Reactive synaptogenesis and neuron densities for neuropeptide Y, somatostatin, and glutamate decarboxylase immunoreactivity in the epileptogenic human fascia dentata

  1995cited by this paper
• Selective Allocation of GABAA Receptors Containing the α1 Subunit to Neurochemically Distinct Subpopulations of Rat Hippocampal Interneurons

  1994cited by this paper
• The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy

  1994cited by this paper
• Kainic acid seizures in the rat.

  1994cited by this paper
• On the relationship between neuropathology and pathophysiology in the epileptic hippocampus of humans and experimental animals

  1994cited by this paper
• Neuronal loss induced in limbic pathways by kindling: evidence for induction of hippocampal sclerosis by repeated brief seizures

  1994cited by this paper
• Loss of glutamate decarboxylase mRNA-containing neurons in the rat dentate gyrus following pilocarpine-induced seizures

  1993cited by this paper
• Circuit Mechanisms of Seizures in the Pilocarpine Model of Chronic Epilepsy: Cell Loss and Mossy Fiber Sprouting

  1993cited by this paper
• Functional changes in neuropeptide Y- and somatostatin-containing neurons induced by limbic seizures in the rat.

  1992cited by this paper
• GABA and epilepsy: basic concepts from preclinical research.

  1992cited by this paper
• Long‐Term Effects of Pilocarpine in Rats: Structural Damage of the Brain Triggers Kindling and Spontaneous I Recurrent Seizures

  1991cited by this paper
• GABA neurons in seizure disorders: A review of immunocytochemical studies

  1991cited by this paper
• Electrophysiology of GABA-mediated synaptic transmission and possible roles in epilepsy

  1991cited by this paper
• A selective loss of somatostatin in the hippocampus of patients with temporal lobe epilepsy

  1991cited by this paper
• Calcium‐binding protein (calbindin‐D28K) and parvalbumin immunocytochemistry in the normal and epileptic human hippocampus

  1991cited by this paper
• Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus

  1989cited by this paper
• Mossy fiber synaptic reorganization in the epileptic human temporal lobe

  1989cited by this paper
• Calcium‐binding protein (calbindin‐D28k) and parvalbumin immunocytochemistry: Localization in the rat hippocampus with specific reference to the selective vulnerability of hippocampal neurons to seizure activity

  1989cited by this paper
• Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy.

  1989cited by this paper
• Decreased hippocampal inhibition and a selective loss of interneurons in experimental epilepsy.

  1987cited by this paper
• Monoclonal antibodies reveal structural homogeneity of gamma-aminobutyric acid/benzodiazepine receptors in different brain areas.

  1985cited by this paper
• Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

  1981cited by this paper

• Antiepileptic Property of Tetraponera aethiops Venom in Pilocarpine-picrotoxin Model of Temporal Lobe Epilepsy

  2025cites this paper
• Hippocampal Interneurons Shape Spatial Coding Alterations in Neurological Disorders

  2025cites this paper
• Effect of GABAa-receptors on neuronal discharge and ion activity in focal seizures.

  2024cites this paper
• Susceptibility to Pentylenetetrazole-Induced Seizures in Mice with Distinct Activity of the Endogenous Opioid System

  2024cites this paper
• Insulin decreases epileptiform activity in rat layer 5/6 prefrontal cortex in vitro

  2023cites this paper
• Inter- and intra-operator variations in manual segmentation of hippocampus from MRI

  2023cites this paper
• Evidence supporting deep brain stimulation of the medial septum in the treatment of temporal lobe epilepsy

  2022cites this paper
• Neuroprotective Efficacy of Quercetin with Lamotrigine and Gabapentin Against Pentylenetetrazole-induced Kindling and Associated Behavioral Comorbidities in Mice

  2022cites this paper
• Cell to network computational model of the epileptic human hippocampus suggests specific roles of network and channel dysfunctions in the ictal and interictal oscillations

  2022cites this paper
• Significance of GABAA Receptor for Cognitive Function and Hippocampal Pathology

  2021cites this paper
• Experimental GABA A Receptor Agonists and Allosteric Modulators for the Treatment of Focal Epilepsy

  2021cites this paper
• Αlpha 5 subunit-containing GABAA receptors in temporal lobe epilepsy with normal MRI

  2021cites this paper
• Increased expression of GABAA receptor subunits associated with tonic inhibition in patients with temporal lobe epilepsy

  2021cites this paper
• Neurosteroids and Focal Epileptic Disorders

  2020cites this paper
• Cannabinoids, TRPV and nitric oxide: the three ring circus of neuronal excitability

  2019cites this paper
• Computational modeling of healthy and epileptic hippocampal oscillations

  2019cites this paper
• Altered immunohistochemical distribution of hippocampal interneurons following traumatic brain injury

  2019influential citation
• Review: Animal models of acquired epilepsy: insights into mechanisms of human epileptogenesis

  2018cites this paper
• De novo variants in GABRA2 and GABRA5 alter receptor function and contribute to early-onset epilepsy

  2018cites this paper
• Cannabidiol exerts antiepileptic effects by restoring hippocampal interneuron functions in a temporal lobe epilepsy model

  2018cites this paper
• Anticonvulsant and Neuroprotective Effects of Cannabidiol During the Juvenile Period

  2018cites this paper
• Disciplinare BIO / 09-Fisiologia ROLE OF NITRIC OXIDE / cGMP PATHWAY IN CANNABINOID MODULATION OF PAROXYSMAL PHENOMENA

  2017cites this paper
• Aqueous extract of Launaea acanthodes induces glutamate uptake and GABA release in astrocyte cell culture via a ROS scavenging mediated process.

  2017cites this paper
• Altered functional efficacy of hippocampal interneuron during epileptogenesis following febrile seizures.

  2017cites this paper
• Epilepsy-associated alterations in hippocampal excitability

  2017cites this paper
• Mechanisms of hyperexcitability and efficacy of antiepileptic drugs in hippocampal-entorhinal networks in the Reduced Intensity Status Epilepticus (RISE) model of chronic epilepsy

  2017cites this paper
• The effects of quercetin on the gene expression of the GABAA receptor α5 subunit gene in a mouse model of kainic acid-induced seizure

  2017cites this paper
• Dentate gyrus autonomous ictal activity in the status epilepticus rat model of epilepsy.

  2017cites this paper
• Disrupted Co-activation of Interneurons and Hippocampal Network after Focal Kainate Lesion

  2017cites this paper
• Comparative performance evaluation of automated segmentation methods of hippocampus from magnetic resonance images of temporal lobe epilepsy patients.

  2016cites this paper
• Inactivation of GABAA receptor is related to heat shock stress response in organism model Caenorhabditis elegans

  2016cites this paper
• Molecular biomarkers in drug-resistant epilepsy: Facts & possibilities.

  2016cites this paper
• Developmental and degenerative modulation of GABAergic transmission in the mouse hippocampus

  2015cites this paper
• Expression of GABA receptor subunits in the hippocampus and thalamus after experimental traumatic brain injury

  2015cites this paper
• Increased Activity of GABA(A) Receptors Contributes to Postanesthetic Memory Deficits

  2015cites this paper
• Pilocarpine-Induced Status Epilepticus Hilar Ectopic Dentate Granule Cells After Enhanced Tonic GABA Current in Normotopic and

  2015cites this paper
• PKCε and allopregnanolone: functional cross-talk at the GABAA receptor level

  2015cites this paper
• Hypothermia mitigates neurochemical alterations in rat's cerebral cortex during status epilepticus induced by pilocarpine.

  2015cites this paper
• Tonic GABAA Receptors as Potential Target for the Treatment of Temporal Lobe Epilepsy

  2015cites this paper
• Two Human Epilepsy Mutations Cause Developmentally Dependant Changes in Seizure Phenotype and GABAA Receptor Expression in Genetically Modified Mice

  2014cites this paper
• Parvalbumin immunoreactivity and expression of GABAA receptor subunits in the thalamus after experimental TBI.

  2014cites this paper
• Review: Hippocampal sclerosis in epilepsy: a neuropathology review

  2014cites this paper
• Interaction of different proteins with GABAA receptor and their modulatory effect on inhibitory neural transmission leads to epilepsy.

  2014cites this paper
• Are alterations in transmitter receptor and ion channel expression responsible for epilepsies?

  2014cites this paper
• The Role of Extrasynaptic GABAA Receptors in Focal Epilepsy

  2014cites this paper
• Regulation of epileptiform activity by two distinct subtypes of extrasynaptic GABAA receptors

  2013cites this paper
• Status epilepticus enhances tonic GABA currents and depolarizes GABA reversal potential in dentate fast-spiking basket cells.

  2013cites this paper
• Tonic GABA(A) receptor-mediated signalling in temporal lobe epilepsy.

  2013cites this paper
• Detection of c-Fos Expression in the Brains of Animals with a Pilocarpine Model of Temporal Lobe Epilepsy

  2013cites this paper
• Histological study of hippocampal cortex after long-term valproate admininistration to rats

  2013cites this paper
• Changes in the expression of GABAA receptor subunit mRNAs in parahippocampal areas after kainic acid induced seizures

  2013cites this paper
• Tonic GABA inhibition in hippocampal dentate granule cells: its regulation and function in temporal lobe epilepsies

  2013cites this paper
• Understanding complexities of synaptic transmission in medically intractable seizures: A paradigm of epilepsy research

  2013cites this paper
• Abnormalities of GABA System and Human Pharmacoresistant Epilepsy

  2013cites this paper
• ESTUDO FARMACOLÓGICO, FISIOLÓGICO E COMPORTAMENTAL DE RATOS TRATADOS COM DOSE SUBCONVULSIVANTE DE PILOCARPINA

  2013cites this paper
• Excitation–Inhibition Epilepsies

  2013cites this paper
• Pharmacoresistance in Epilepsy

  2013cites this paper
• GABAA receptor modulation by neurosteroids in models of temporal lobe epilepsies

  2012cites this paper
• Antioxidant Treatments: Effect on Behaviour, Histopathological and Oxidative Stress in Epilepsy Model

  2012cites this paper
• Functional regulation of GABAA receptors in nervous system pathologies.

  2012cites this paper
• [Detection of c-fos expression in animal brain in a pilocarpine model of temporal lobe epilepsy].

  2012cites this paper
• Understanding the basic mechanisms underlying seizures in mesial temporal lobe epilepsy and possible therapeutic targets: A review

  2012cites this paper
• Functional properties of ion channels and transporters contributing to the synaptic inhibition in the mammalian central nervous system

  2012cites this paper
• Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice.

  2011cites this paper
• Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy.

  2011cites this paper
• Distinct expression patterns of four GABARA subunits in human epileptic cortex and low-grade glioma

  2011cites this paper
• Recombinant GABAA receptor expression in the baculovirus expression system

  2011cites this paper
• Morpho-physiological analysis of interneuronal populations in the rat piriform cortex before and after kindling induced epilepsy

  2011cites this paper
• Inhibiting inhibition: interactions amongst interneurons of the hippocampus

  2011cites this paper
• GABAergic synchronization in the limbic system and its role in the generation of epileptiform activity.

  2011cites this paper
• Altered GABA Signaling in Early Life Epilepsies

  2011cites this paper
• Role of nogo - a in the intact central nervous system: an in vivo and in vitro approach.

  2011cites this paper
• Progressive loss of phasic, but not tonic, GABAA receptor-mediated inhibition in dentate granule cells in a model of post-traumatic epilepsy in rats.

  2011cites this paper
• GABAergic Circuit Development and Its Implication for CNS Disorders

  2011influential citation
• Alterations of Calcium-binding protein immunoreactivities in the Hippocampus following Traumatic brain injury

  2011influential citation
• Histopathological Changes in Temporal Epilepsy

  2011cites this paper
• Altered GABA(A) receptor expression during epileptogenesis.

  2011cites this paper
• Characterisation of response to antiepileptic drugs

  2010cites this paper
• Initial loss but later excess of GABAergic synapses with dentate granule cells in a rat model of temporal lobe epilepsy

  2010cites this paper
• Proteomic Profiling of the Epileptic Dentate Gyrus

  2010cites this paper
• Transcriptome Analysis of the Hippocampal CA1 Pyramidal Cell Region after Kainic Acid-Induced Status Epilepticus in Juvenile Rats

  2010cites this paper
• Lipoic acid effects on monoaminergic system after pilocarpine-induced seizures.

  2010cites this paper
• Diverse interneuron populations have highly specific interconnectivity in the rat piriform cortex

  2010cites this paper
• LOCAL SYNAPTIC NETWORK INTERACTIONS IN THE DENTATE GYRUS OF A CORTICAL CONTUSION MODEL OF POSTTRAUMATIC EPILEPSY

  2010cites this paper
• Anticonvulsant and antioxidant effects of 3-alkynyl selenophene in 21-day-old rats on pilocarpine model of seizures.

  2009cites this paper
• Animal Models of Epilepsy

  2009cites this paper
• Cortical kindling induces elevated levels of AMPA and GABA receptor subunit mRNA within the amygdala/piriform region and is associated with behavioral changes in the rat.

  2009cites this paper
• Interneuron Loss as a Cause of Seizures: Lessons from Interneuron-Deficient Mice

  2009cites this paper
• Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis.

  2009cites this paper
• The regulatory properties of α5 subunit-containing γ-aminobutyric acid subtype A receptors in learning and synaptic plasticity.

  2009influential citation
• Surviving Hilar Somatostatin Interneurons Enlarge, Sprout Axons, and Form New Synapses with Granule Cells in a Mouse Model of Temporal Lobe Epilepsy

  2009cites this paper
• Enhanced tonic GABA current in normotopic and hilar ectopic dentate granule cells after pilocarpine-induced status epilepticus.

  2009cites this paper
• Selective changes in GABAA receptor subtypes in white matter neurons of patients with focal epilepsy.

  2009cites this paper
• Pentoxifylline ameliorates lithium-pilocarpine induced status epilepticus in young rats.

  2008cites this paper
• Decreased efficacy of GABA A receptor modulation by midazolam in the kainate model of temporal lobe epilepsy

  2008cites this paper
• Regulation of Burst Activity through Presynaptic and Postsynaptic GABAB Receptors in Mouse Superior Colliculus

  2008cites this paper
• Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy.

  2008cites this paper
• Regulation of excitability by extrasynaptic GABA(A) receptors.

  2008cites this paper
• Antiepileptic drug resistant rats differ from drug responsive rats in GABA A receptor subunit expression in a model of temporal lobe epilepsy.

  2008cites this paper
• Modulation of epileptiform activity by activation of tonic inhibition

  2008cites this paper