Purification and characterization of bovine cardiac calmodulin-dependent myosin light chain kinase.

No abstract is available for this paper.

• Publication year

  1979

• Venue

  Journal of Biological Chemistry

• Publication date

  1979-12-10

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 500701
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Amino acid sequence at the site on rabbit skeletal muscle glycogen synthase phosphorylated by the endogenous glycogen synthase kinase‐2 activity

  1979cited by this paper
• Human platelet myosin light chain kinase requires the calcium-binding protein calmodulin for activity.

  1979cited by this paper
• Cyclic AMP-dependent ATPase activity of bovine heart protein kinase.

  1979cited by this paper
• Calmodulin and myosin light-chain kinase of rabbit fast skeletal muscle.

  1979cited by this paper
• Effect of proteases on the structure and activity of rabbit skeletal muscle glycogen synthetase

  1979cited by this paper
• Phosphorylation of smooth muscle myosin light chain kinase by the catalytic subunit of adenosine 3': 5'-monophosphate-dependent protein kinase.

  1978cited by this paper
• Purification of modulator-deficient myosin light-chain kinase by modulator protein-Sepharose affinity chromatography.

  1978cited by this paper
• Preparation, characterization, and properties of a novel triple-modified derivative of the Ca2+ -dependent protein modulator.

  1978cited by this paper
• A Ca2+-and modulator-dependent myosin light chain kinase from non-muscle cells.

  1978cited by this paper
• The modulator-dependent protein kinase. A multifunctional protein kinase activatable by the Ca2+-dependent modulator protein of the cyclic nucleotide system.

  1978cited by this paper
• Selective precipitation of 32Pi onto filter papers. Application to ATPase and cyclic AMP phosphodiesterase determination.

  1978cited by this paper
• Cyclic 3′,5′-Nucleotides: mechanisms of action : by H. Cramer and J. Schultz John Wiley; Chichester, 1977 xiv + 554 pages. £17.50; $34.50

  1978cited by this paper
• Identification of Ca2+‐binding subunit of myosin light chain kinase from skeletal muscle with modulator protein

  1978cited by this paper
• Purification of cyclic 3',5'-nucleotide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to Sepharose.

  1978cited by this paper
• Studies on the structure and mechanism of activation of the guanosine 3':5'-monophosphate-dependent protein kinase.

  1978cited by this paper
• Effects of chymotrypsin and a calcium-dependent protein activator on guanosine 3',5'-monophosphate phosphodiesterase from rat liver.

  1978cited by this paper
• Thick-filament-linked calcium regulation in vertebrate striated muscle

  1978cited by this paper
• Interaction of skeletal myosin light chains with calcium ions.

  1978cited by this paper
• Modulator protein as a component of the myosin light chain kinase from chicken gizzard.

  1978cited by this paper
• Stimulation of cyclic nucleotide phosphodiesterases from rat brain by activator protein, proteolytic enzymes and a vitamin E derivative.

  1977cited by this paper
• Calcium ion-dependent myosin from decapod-crustacean muscles.

  1977cited by this paper
• Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

  1977cited by this paper
• Effect of phosphorylation of smooth muscle myosin on actin activation and Ca2+ regulation.

  1977cited by this paper
• Adenosine 3':5'-monophosphate dependent protein kinase from bovine heart. Characterization of the catalytic subunit.

  1977cited by this paper
• Isolation and properties of the rabbit skeletal muscle protein inhibitor of adenosine 3',5'-monophosphate dependent protein kinases.

  1977cited by this paper
• Composition of the myosin light chain kinase from chicken gizzard.

  1977cited by this paper
• Purification and properties of myosin light-chain kinase from fast skeletal muscle.

  1977cited by this paper
• Separation of low molecular components of pig cardiac myosin and myosin subfragment-1, and Ca2+ binding to one of the components (g2)

  1977cited by this paper
• Myosin light-chain phosphatase.

  1976cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• A relationship between Ca2+ sensitivity and phosphorylation of gizzard actomyosin.

  1976cited by this paper
• Isolation and properties of platelet myosin light chain kinase.

  1976cited by this paper
• Identification of a calcium-binding protein as a calcium-dependent regulator of brain adenylate cyclase.

  1975cited by this paper
• Protein activator of cyclic 3':5'-nucleotide phosphodiesterase of bovine or rat brain also activates its adenylate cyclase.

  1975cited by this paper
• Preparation and properties of vertebrate smooth-muscle myofibrils and actomyosin.

  1975cited by this paper
• Phosphorylation of the light-chain components of myosin from cardiac and red skeletal muscles.

  1975cited by this paper
• X-ray evidence for conformational changes in the myosin filaments of vertebrate striated muscle.

  1975cited by this paper
• The binding of divalent cations to myosin.

  1975cited by this paper
• Assay of cyclic nucleotide phosphodiesterases with radioactive substrates.

  1974cited by this paper
• Evidence for structural changes in vertebrate thick filaments induced by calcium.

  1974cited by this paper
• Myosin light‐chain kinase, a new enzyme from striated muscle

  1974cited by this paper
• Glycogen synthetase kinase 2 (GSK 2); The identification of a new protein kinase in skeletal muscle

  1974cited by this paper
• Purification and properties of the protein activator of bovine heart cyclic adenosine 3',5'-monophosphate phosphodiesterase.

  1973cited by this paper
• Molecular control mechanisms in muscle contraction.

  1973cited by this paper
• The subunit structure of rabbit-skeletal-muscle phosphorylase kinase, and the molecular basis of its activation reactions.

  1973cited by this paper
• Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.

  1971cited by this paper
• An electrophoretic study of the low-molecular-weight components of myosin.

  1970cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• Water and electrolyte metabolism and acid-base balance

  1968cited by this paper
• A new micromethod for the colorimetric determination of inorganic phosphate.

  1966cited by this paper
• A simple method for the preparation of 32-P-labelled adenosine triphosphate of high specific activity.

  1964cited by this paper

• β-adrenergic activation may promote myosin light chain kinase degradation through calpain in pressure overload-induced cardiac hypertrophy: β-adrenergic activation results in MLCK degradation.

  2020cites this paper
• Angiotensin Receptor II type 1 and the activation of Myosin Light-Chain Kinase and Protein Kinase C-βII. Mini Review.

  2019cites this paper
• Polymyxin B enhances acrosomal exocytosis triggered by calcium and the calcium ionophore A23187 in ejaculated boar spermatozoa

  2019cites this paper
• cardiac and skeletal muscle Smooth muscle myosin light chain kinase expression in

  2016cites this paper
• Dysferlin deficiency blunts β‐adrenergic‐dependent lusitropic function of mouse heart

  2015cites this paper
• Current Concepts in the Role of Mechanosensing in the Regulation of Cardiac Contractile Function

  2015cites this paper
• Getting the skinny on thick filament regulation in cardiac muscle biology and disease.

  2014cites this paper
• Smooth muscle myosin light chain kinase efficiently phosphorylates serine 15 of cardiac myosin regulatory light chain.

  2011cites this paper
• Effects of the Balance in Activity of RhoA and Rac1 on the Shock-Induced Biphasic Change of Vascular Reactivity in Rats

  2011cites this paper
• The significance of regulatory light chain phosphorylation in cardiac physiology.

  2011cites this paper
• The role of protein kinase C-mediated phosphorylation of sarcomeric proteins in the heart—detrimental or beneficial?

  2011cites this paper
• The mechanism by which RhoA regulates vascular reactivity after hemorrhagic shock in rats.

  2010cites this paper
• Metformin blocks migration and invasion of tumour cells by inhibition of matrix metalloproteinase‐9 activation through a calcium and protein kinase Cα‐dependent pathway: phorbol‐12‐myristate‐13‐acetate‐induced/extracellular signal‐regulated kinase/activator protein‐1

  2010cites this paper
• Effects of trifluoperazine on beta-adrenergic responses of rat papillary muscle: related to calmodulin?

  2009cites this paper
• Identification of Early Intestinal Neoplasia Protein Biomarkers Using Laser Capture Microdissection and MALDI MS*S

  2009cites this paper
• Myosin Regulatory Light Chain Phosphorylation Attenuates Cardiac Hypertrophy*

  2008cites this paper
• Development of a new Ca2+/calmodulin antagonist and its anti-proliferative activity against colorectal cancer cells.

  2007cites this paper
• MECHANISMS OF RHO KINASE REGULATION OF VASCULAR REACTIVITY FOLLOWING HEMORRHAGIC SHOCK IN RATS

  2007cites this paper
• Discovery of new small molecules and targets towards angiogenesis via chemical genomics approach.

  2006cites this paper
• A novel fluorescent probe for protein binding and folding studies: p-cyano-phenylalanine.

  2006cites this paper
• The Ca2+-calmodulin dependent protein kinase II system of skeletal muscle sarcoplasmic reticulum

  2005cites this paper
• Ion binding to calmodulin

  2004cites this paper
• A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function.

  2004cites this paper
• Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.

  2000influential citation
• Intracellular function in rehydrated lyophilized platelets.

  2000cites this paper
• Intracellular function in rehydrated lyophilized platelets

  2000influential citation
• Demonstration of a Ca2+/calmodulin dependent protein kinase cascade in the hog heart.

  1998cites this paper
• Myosin-light-chain kinase

  1997cites this paper
• Biochemical characterization of Pkn2, a protein Ser/Thr kinase from Myxococcus xanthus, a Gram‐negative developmental bacterium

  1997cites this paper
• A novel Ca2+/calmodulin-dependent protein kinase lacking autophosphorylation activity in the rabbit heart.

  1995cites this paper
• Changes in the activities of protein kinases A, C, and M in dog heart and liver following endotoxin administration.

  1994cites this paper
• Beta-adrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats.

  1994cites this paper
• Structural requirement of the regulatory light chain of smooth muscle myosin as a substrate for myosin light chain kinase.

  1994cites this paper
• Identification of a calcium dependent atrial secretory binding protein as calmodulin.

  1994cites this paper
• Cell-cycle-dependent regulation of myosin light chain kinase.

  1994cites this paper
• Phosphorylation of cardiac myosin light chain 2 by protein kinase C and myosin light chain kinase increases Ca(2+)-stimulated actomyosin MgATPase activity.

  1993cites this paper
• Protein kinase C enhances myosin light-chain kinase effects on force development and ATPase activity in rat single skinned cardiac cells.

  1992cites this paper
• Phosphorylation and activation of tyrosine hydroxylase in PC18 cells: a cell line derived from rat pheochromocytoma PC12 cells.

  1992cites this paper
• Effect of Calmodulin and Protein Kinase C Inhibitors on Globally Ischemic Rat Hearts

  1992cites this paper
• Phosphorylation of chicken cardiac C-protein by calcium/calmodulin-dependent protein kinase II.

  1991cites this paper
• Contractile proteins in globally “stunned” rabbit myocardium

  1991cites this paper
• Inflammatory agonists that increase microvascular permeability in vivo stimulate cultured pulmonary microvessel endothelial cell contraction

  1990cites this paper
• Modulation of the stability of rabbit skeletal muscle myosin light chain kinase through the calmodulin-binding domain.

  1990cites this paper
• Calmodulin and troponin C structures studied by Fourier transform infrared spectroscopy: effects of Ca2+ and Mg2+ binding.

  1989cites this paper
• Anti-gizzard MLCK monoclonal antibody MM13 inhibits superprecipitation and phosphorylation of bovine aortic smooth muscle actomyosin.

  1989cites this paper
• Monoclonal antibody assessment of tissue- and species-specific myosin light chain kinase isozymes.

  1989cites this paper
• Purification and characterization of a calcium-calmodulin-dependent phospholamban kinase from canine myocardium.

  1989cites this paper
• A galactose-dependent cmd1 mutant of Saccharomyces cerevisiae: involvement of calmodulin in nuclear division

  1989cites this paper
• Effects of calcium and calcium analogs on calmodulin: a Fourier transform infrared and electron spin resonance investigation.

  1989cites this paper
• Calmodulin and troponin C structures studied by Fourier transform infrared spectroscopy: effects of calcium and magnesium binding

  1989cites this paper
• Ultracytochemistry of calmodulin binding sites in myocardial cells by staining of frozen thin sections with colloidal gold-labeled calmodulin.

  1989cites this paper
• Pharmacological modulation of phosphorylation mechanisms in heart and vasculature

  1988cites this paper
• Different phosphorylation patterns of cardiac myosin light chains using ATP and ATP gamma S as substrates.

  1988cites this paper
• Increased calcium sensitivity of chemically skinned human atria by myosin light chain kinase

  1988cites this paper
• Anti-ischaemic activity of various calmodulin antagonists.

  1988cites this paper
• [Correlation between myocardial relaxation and phosphorylation of phospholamban].

  1988cites this paper
• Dissociation between contraction and relaxation: The possible role of phospholamban phosphorylation

  1987cites this paper
• Protein serine/threonine kinases.

  1987cites this paper
• ORGANIZATION OF MYOSIN LIGHT CHAIN KINASE FROM RABBIT SKELETAL MUSCLE

  1987cites this paper
• Chapter 3 – Calcium/Calmodulin-Dependent Protein Kinases

  1987cites this paper
• Identification of membrane-bound calcium, calmodulin-dependent protein kinase II in canine heart.

  1987cites this paper
• Phosphorylation sites of bovine brain myelin basic protein phosphorylated with Ca2+-calmodulin-dependent protein kinase from rat brain.

  1987cites this paper
• Characterization of regulatory light chain-a myosin kinase from smooth muscle of scallop, Patinopecten yessoensis.

  1987cites this paper
• Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C).

  1986cites this paper
• Smooth muscle myosin light chain kinase. Amino acid sequence at the site phosphorylated by adenosine cyclic 3',5'-phosphate-dependent protein kinase whether or not calmodulin is bound.

  1986cites this paper
• Myosin light chain kinase and cyclic AMP-dependent protein kinase activities and calmodulin levels in placental and non-placental regions of the rabbit myometrium.

  1986cites this paper
• Purification and characterization of a phosphoprotein phosphatase that dephosphorylates myosin and the isolated light chain from chicken gizzard smooth muscle.

  1986cites this paper
• The turnover of phosphate bound to myosin light chain-2 in perfused rat heart.

  1986cites this paper
• Effects of selenium compounds on phospholipid/Ca2+-dependent protein kinase (protein kinase C) system from human leukemic cells.

  1986cites this paper
• Suggestion of a role for calmodulin and phosphorylation in regulation of rabbit ileal electrolyte transport: effects of promethazine.

  1986cites this paper
• Purification and characterization of a multifunctional calmodulin-dependent protein kinase from canine myocardial cytosol.

  1986cites this paper
• Characterization and partial purification of cardiac sarcoplasmic reticulum phospholamban kinase.

  1986cites this paper
• Characterization of chicken skeletal muscle myosin light chain kinase. Evidence for muscle-specific isozymes.

  1985cites this paper
• Effect of tamoxifen, a nonsteroidal antiestrogen, on phospholipid/calcium-dependent protein kinase and phosphorylation of its endogenous substrate proteins from the rat brain and ovary.

  1985cites this paper
• The calmodulin-dependent phosphorylation of cardiac myosin.

  1985cites this paper
• Calcium Regulation of Smooth Muscle Actomyosin

  1985cites this paper
• Myosin light chain kinases and myosin phosphorylation in skeletal muscle.

  1985cites this paper
• The link between myocardial contraction and relaxation: the effects of calcium antagonists.

  1985cites this paper
• Polyclonal antibodies to phospholipid/Ca2+-dependent protein kinase and immunocytochemical localization of the enzyme in rat brain.

  1985cites this paper
• Role of Calmodulin in the Regulation of Muscle Contraction

  1985cites this paper
• Phosphorylation of myosin light chain kinase from vascular smooth muscle by cAMP- and cGMP-dependent protein kinases.

  1985cites this paper
• Phosphorylation reaction of vertebrate smooth muscle myosin: an enzyme kinetic analysis.

  1985cites this paper
• Identification of a calmodulin-dependent protein kinase in the cardiac cytosol, which phosphorylates phospholamban in the sarcoplasmic reticulum.

  1985cites this paper
• Inhibition of phospholipid/Ca2+-dependent protein kinase and phosphorylation of leukemic cell proteins by CP-46,665-1, a novel antineoplastic lipoidal amine.

  1985cites this paper
• Phosphorylation in isolated Chlamydomonas axonemes: a phosphoprotein may mediate the Ca2+-dependent photophobic response

  1985cites this paper
• Regulation of Contractility in Developing Heart

  1984cites this paper
• Hormonal regulation of protein phosphorylation in isolated rat heart cells.

  1984cites this paper
• Phospholipid-sensitive Ca2+-dependent protein kinase inhibition by R-24571, a calmodulin antagonist.

  1984cites this paper
• Calcium-ion and calmodulin-dependent kappa-casein kinase in rat mammary acini.

  1984cites this paper
• Unchanged myosin kinase activity in hypertrophied rat heart.

  1984cites this paper
• Changes in calmodulin level after fertilization and during first cleavage in the egg of the urodelan amphibian Pleurodeles waltlii.

  1984cites this paper
• Aging and Cell Function

  1984cites this paper
• Role of Calmodulin in Neurotransimitter Syntheis

  1984cites this paper
• Calmodulin during development and metamorphosis in urodelan amphibians.

  1984cites this paper
• Regulation of monoamine biosynthesis by calmodulin-dependent protein kinase in the nervous system.

  1984cites this paper
• Protein substrate specificity of a calmodulin-dependent protein kinase isolated from bovine heart.

  1984cites this paper
• Environmental pollutant Cd2+ biphasically and differentially regulates myosin light chain kinase and phospholipid/Ca2+‐dependent protein kinase

  1984cites this paper
• Age-Related Alterations in β-Adrenergic Modulation of Cardiac Cell Function

  1984cites this paper
• Characterization of calmodulin-activated protein kinase activity of rat adipocyte endoplasmic reticulum fraction.

  1984cites this paper
• Phospholipid-Sensitive Ca2+-Dependent Protein Phosphorylation

  1984cites this paper