Synaptopodin couples epithelial contractility to α-actinin-4–dependent junction maturation

Nivetha Kannan,V. Tang

Published 2015 in Journal of Cell Biology

ABSTRACT

A novel tension-sensitive junctional protein, synaptopodin, can relay biophysical input from cellular actomyosin contractility to induce biochemical changes at cell–cell contacts, resulting in structural reorganization of the junctional complex and epithelial barrier maturation.

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