Gut immune deficits in LEW.1AR1‐iddm rats partially overcome by feeding a diabetes‐protective diet

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Immunology

• Publication date

  2015-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/imm.12457PMID 25711680PMCID PMC4479540
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Variable immune cell frequencies in peripheral blood of LEW.1AR1‐iddm rats over time compared to other congenic LEW strains

  2014cited by this paper
• Influence of dietary factors and gut microbiota on type 1 diabetes

  2014cited by this paper
• Islet infiltration, cytokine expression and beta cell death in the NOD mouse, BB rat, Komeda rat, LEW.1AR1-iddm rat and humans with type 1 diabetes

  2014cited by this paper
• Beyond genetics. Influence of dietary factors and gut microbiota on type 1 diabetes

  2014cited by this paper
• A Variable CD3+ T-Cell Frequency in Peripheral Blood Lymphocytes Associated with Type 1 Diabetes Mellitus Development in the LEW.1AR1-iddm Rat

  2013cited by this paper
• Promotion of Autoimmune Diabetes by Cereal Diet in the Presence or Absence of Microbes Associated With Gut Immune Activation, Regulatory Imbalance, and Altered Cathelicidin Antimicrobial Peptide

  2013cited by this paper
• Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice

  2012cited by this paper
• Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

  2012cited by this paper
• IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist

  2012cited by this paper
• Treg cells in pancreatic lymph nodes: the possible role in diabetogenesis and β cell regeneration in a T1D model

  2012cited by this paper
• A cluster of coregulated genes determines TGF-β–induced regulatory T-cell (Treg) dysfunction in NOD mice

  2011cited by this paper
• Current State of Type 1 Diabetes Immunotherapy: Incremental Advances, Huge Leaps, or More of the Same?

  2011cited by this paper
• Decreased frequencies of CD4+CD25+Foxp3+ cells and the potent CD103+ subset in peripheral lymph nodes correlate with autoimmune disease predisposition in some strains of mice

  2011cited by this paper
• Stabilin‐1/CLEVER‐1, a type 2 macrophage marker, is an adhesion and scavenging molecule on human placental macrophages

  2011cited by this paper
• Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice

  2011cited by this paper
• Defective Differentiation of Regulatory FoxP3+ T Cells by Small-Intestinal Dendritic Cells in Patients With Type 1 Diabetes

  2011cited by this paper
• Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans

  2011cited by this paper
• Towards secondary prevention of Type 1 diabetes

  2011cited by this paper
• Common Lymphatic Endothelial and Vascular Endothelial Receptor-1 Mediates the Transmigration of Regulatory T Cells across Human Hepatic Sinusoidal Endothelium

  2011cited by this paper
• Comment on “Type 1 Diabetes in BioBreeding Rats Is Critically Linked to an Imbalance between Th17 and Regulatory T Cells and an Altered TCR Repertoire”

  2011cited by this paper
• Antibodies from a patient with type 1 diabetes and celiac disease bind to macrophages that express the scavenger receptor CD163.

  2011cited by this paper
• Association of the NFKBIA gene polymorphisms with susceptibility to autoimmune and inflammatory diseases: a meta-analysis

  2010cited by this paper
• Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice

  2010cited by this paper
• Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat

  2010cited by this paper
• Type 1 Diabetes in BioBreeding Rats Is Critically Linked to an Imbalance between Th17 and Regulatory T Cells and an Altered TCR Repertoire

  2010cited by this paper
• Immunosuppressive therapy exacerbates autoimmunity in NOD mice and diminishes the protective activity of regulatory T cells.

  2010cited by this paper
• Enhanced islet expansion by β‐cell proliferation in young diabetes‐prone rats fed a protective diet

  2010cited by this paper
• Intestinal Immune Regulation as a Potential Diet-Modifiable Feature of Gut Inflammation and Autoimmunity

  2009cited by this paper
• Stabilin-1 mediates phosphatidylserine-dependent clearance of cell corpses in alternatively activated macrophages

  2009cited by this paper
• Diabetes-Specific HLA-DR–Restricted Proinflammatory T-Cell Response to Wheat Polypeptides in Tissue Transglutaminase Antibody–Negative Patients With Type 1 Diabetes

  2009cited by this paper
• Memory-like CD8+ and CD4+ T cells cooperate to break peripheral tolerance under lymphopenic conditions

  2008cited by this paper
• The mutation of the LEW.1AR1-iddm rat maps to the telomeric end of rat chromosome 1

  2008cited by this paper
• CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity

  2008cited by this paper
• The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells1

  2008cited by this paper
• The CXCR4/CXCL12 (SDF‐1) signalling pathway protects non‐obese diabetic mouse from autoimmune diabetes

  2007cited by this paper
• CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages

  2007cited by this paper
• Increased intestinal permeability precedes clinical onset of type 1 diabetes

  2006cited by this paper
• Dietary proteins as environmental modifiers of type 1 diabetes mellitus.

  2006cited by this paper
• Zonulin Upregulation Is Associated With Increased Gut Permeability in Subjects With Type 1 Diabetes and Their Relatives

  2006cited by this paper
• Novel Function of Alternatively Activated Macrophages: Stabilin-1-Mediated Clearance of SPARC1

  2006cited by this paper
• Immune cell infiltration, cytokine expression, and beta-cell apoptosis during the development of type 1 diabetes in the spontaneously diabetic LEW.1AR1/Ztm-iddm rat.

  2005cited by this paper
• Gut Permeability and Intestinal Mucins, Invertase, and Peroxidase in Control and Diabetes-Prone BB Rats Fed Either a Protective or a Diabetogenic Diet

  2005cited by this paper
• Endocrine self and gut non-self intersect in the pancreatic lymph nodes.

  2005cited by this paper
• Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats.

  2005cited by this paper
• Wheat protein-induced proinflammatory T helper 1 bias in mesenteric lymph nodes of young diabetes-prone rats

  2005cited by this paper
• Genetic analysis of the LEW.1AR1-iddm rat: an animal model for spontaneous diabetes mellitus

  2005cited by this paper
• Effects of polyinosinic-polycytidylic acid and adoptive transfer of immune cells in the LEW.1AR1-iddm rat and in its coisogenic LEW.1AR1 background strain

  2005cited by this paper
• Insulin-dependent diabetes and gut dysfunction: the BB rat model.

  2004cited by this paper
• In vitro-deranged intestinal immune response to gliadin in type 1 diabetes.

  2004cited by this paper
• Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

  2004cited by this paper
• A waxing and waning skin rash

  2004cited by this paper
• T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3.

  2003cited by this paper
• A Type 1 Diabetes-related Protein from Wheat (Triticum aestivum)

  2003cited by this paper
• Gluten Sensitivity in a Subset of Children With Insulin Dependent Diabetes Mellitus

  2003cited by this paper
• A multi-centre, blinded international trial of the effect of A1 and A2 β-casein variants on diabetes incidence in two rodent models of spontaneous Type I diabetes

  2002cited by this paper
• Oral exposure to diabetes-promoting food or immunomodulators in neonates alters gut cytokines and diabetes.

  2002cited by this paper
• BB rat lyp mutation and Type 1 diabetes

  2001cited by this paper
• The LEW.1AR1/Ztm-iddm rat: a new model of spontaneous insulin-dependent diabetes mellitus

  2001cited by this paper
• Translating data from animal models into methods for preventing human autoimmune diabetes mellitus: caveat emptor and primum non nocere.

  2001cited by this paper
• Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat.

  1999cited by this paper
• Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat.

  1999cited by this paper
• The Thymus Contains a High Frequency of Cells that Prevent Autoimmune Diabetes on Transfer into Prediabetic Recipients

  1996cited by this paper
• Food-induced type 1 diabetes in the BB rat.

  1996cited by this paper

• Host-microbiota interactions shaping T-cell response and tolerance in type 1 diabetes

  2022cites this paper
• Rat Models of Human Type 1 Diabetes.

  2020cites this paper
• Epigenetic Effects of Gut Metabolites: Exploring the Path of Dietary Prevention of Type 1 Diabetes

  2020cites this paper
• Probiotics and Prebiotics for the Amelioration of Type 1 Diabetes: Present and Future Perspectives

  2019cites this paper
• Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility

  2018cites this paper
• Changes in immune cell frequencies in primary and secondary lymphatic organs of LEW.1AR1-iddm rats, a model of human type 1 diabetes compared to other MHC congenic LEW inbred strains

  2018cites this paper
• Changes in insulin, glucagon and ER stress precede immune activation in type 1 diabetes.

  2018cites this paper