Hippocampal involvement in contextual modulation of fear extinction

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Hippocampus

• Publication date

  2007-09-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1002/HIPO.20331PMID 17604353
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Critical Analysis of Approaches to Targeted PTSD Prevention

  2007cited by this paper
• Hippocampal regulation of context-dependent neuronal activity in the lateral amygdala.

  2007cited by this paper
• Prefrontal mechanisms in extinction of conditioned fear.

  2006cited by this paper
• The anatomy of fear extinction.

  2006cited by this paper
• Recent fear is resistant to extinction

  2006cited by this paper
• Intertrial interval as a contextual stimulus.

  2006cited by this paper
• Contextual and temporal modulation of extinction: behavioral and biological mechanisms.

  2006influential reference
• Context-Dependent Human Extinction Memory Is Mediated by a Ventromedial Prefrontal and Hippocampal Network

  2006influential reference
• Neural circuits and mechanisms involved in Pavlovian fear conditioning: a critical review.

  2006cited by this paper
• Reinstatement of conditioned fear in humans is context dependent and impaired in amnesia.

  2005cited by this paper
• Electrolytic lesions of the dorsal hippocampus disrupt renewal of conditional fear after extinction.

  2005influential reference
• Behavioral / Systems / Cognitive Hippocampal Inactivation Disrupts the Acquisition and Contextual Encoding of Fear Extinction

  2005influential reference
• Building and Burying Fear Memories in the Brain

  2005influential reference
• Neuronal signalling of fear memory

  2004cited by this paper
• Emotional perseveration: an update on prefrontal-amygdala interactions in fear extinction.

  2004influential reference
• Context and behavioral processes in extinction.

  2004influential reference
• Spontaneous recovery.

  2004cited by this paper
• Factors regulating the effects of hippocampal inactivation on renewal of conditional fear after extinction.

  2004influential reference
• Auditory-evoked spike firing in the lateral amygdala and Pavlovian fear conditioning: mnemonic code or fear bias?

  2003cited by this paper
• Convergence and Interaction of Hippocampal and Amygdalar Projections within the Prefrontal Cortex in the Rat

  2003cited by this paper
• Context-Dependent Neuronal Activity in the Lateral Amygdala Represents Fear Memories after Extinction

  2003influential reference
• Massive extinction treatment attenuates the renewal effect

  2003cited by this paper
• Memory for extinction of conditioned fear is long-lasting and persists following spontaneous recovery.

  2002cited by this paper
• Neurons in medial prefrontal cortex signal memory for fear extinction

  2002cited by this paper
• Cellular Mechanisms of Infralimbic and Prelimbic Prefrontal Cortical Inhibition and Dopaminergic Modulation of Basolateral Amygdala Neurons In Vivo

  2002cited by this paper
• The role of amygdala glutamate receptors in fear learning, fear-potentiated startle, and extinction.

  2002cited by this paper
• Behavioral and neural analysis of extinction.

  2002influential reference
• The human hippocampus and spatial and episodic memory.

  2002cited by this paper
• Context, ambiguity, and unlearning: sources of relapse after behavioral extinction.

  2002influential reference
• Conjunctive representations in learning and memory: principles of cortical and hippocampal function.

  2001cited by this paper
• Combined effect of context change and retention interval on interference in causality judgments.

  2001cited by this paper
• Hippocampal Inactivation Disrupts Contextual Retrieval of Fear Memory after Extinction

  2001influential reference
• Dopamine Attenuates Prefrontal Cortical Suppression of Sensory Inputs to the Basolateral Amygdala of Rats

  2001cited by this paper
• Conjunctive representations, the hippocampus, and contextual fear conditioning

  2001cited by this paper
• Mitogen-Activated Protein Kinase Cascade in the Basolateral Nucleus of Amygdala Is Involved in Extinction of Fear-Potentiated Startle

  2001cited by this paper
• Treatments that weaken Pavlovian conditioned fear and thwart its renewal in rats: implications for treating human phobias.

  2001cited by this paper
• Extinction and spontaneous recovery of ataxic tolerance to ethanol in rats

  2001cited by this paper
• Neurobiology of Pavlovian fear conditioning.

  2001influential reference
• The hippocampus and declarative memory: cognitive mechanisms and neural codes.

  2001cited by this paper
• The effects of neurotoxic hippocampal lesions on two effects of context after fear extinction.

  2000influential reference
• A cortical–hippocampal system for declarative memory

  2000cited by this paper
• Renewal of Extinguished Lever-Press Responses upon Return to the Training Context

  2000cited by this paper
• The hippocampus and contextual memory retrieval in Pavlovian conditioning.

  2000influential reference
• Auditory fear conditioning increases CS‐elicited spike firing in lateral amygdala neurons even after extensive overtraining

  2000cited by this paper
• The Role of Ventromedial Prefrontal Cortex in the Recovery of Extinguished Fear

  2000cited by this paper
• Reciprocal Connections between the Amygdala and the Hippocampal Formation, Perirhinal Cortex, and Postrhinal Cortex in Rat: A Review

  2000cited by this paper
• Contextual fear, gestalt memories, and the hippocampus.

  2000cited by this paper
• Hippocampo‐prefrontal cortex pathway: Anatomical and electrophysiological characteristics

  2000cited by this paper
• Recent and Remote Extinction Cues Reduce Spontaneous Recovery

  2000cited by this paper
• Context-specificity of relapse: effects of therapist and environmental context on return of fear.

  1999cited by this paper
• The effects of changing contexts on return of fear following exposure therapy for spider fear.

  1999cited by this paper
• Modulation of Basolateral Amygdala Neuronal Firing and Afferent Drive by Dopamine Receptor Activation In Vivo

  1999cited by this paper
• Attenuation of the Renewal Effect by Extinction in Multiple Contexts

  1999cited by this paper
• Muscimol Inactivation of the Dorsal Hippocampus Impairs Contextual Retrieval of Fear Memory

  1999cited by this paper
• Hippocampal lesions interfere with Pavlovian negative occasion setting

  1999cited by this paper
• Temporally Graded Retrograde Amnesia of Contextual Fear after Hippocampal Damage in Rats: Within-Subjects Examination

  1999cited by this paper
• Lesions of periaqueductal gray dissociate-conditioned freezing from conditioned suppression behavior in rats.

  1999cited by this paper
• Contextual fear conditioning, conjunctive representations, pattern completion, and the hippocampus.

  1999cited by this paper
• Context change and retention interval can have additive, rather than interactive, effects after taste aversion extinction

  1998cited by this paper
• Conducting exposure treatment in multiple contexts can prevent relapse.

  1998cited by this paper
• Neurotoxic lesions of the dorsal hippocampus and Pavlovian fear conditioning in rats.

  1997cited by this paper
• N-methyl-D-aspartate receptors in the basolateral amygdala are required for both acquisition and expression of conditional fear in rats.

  1996cited by this paper
• Structure and function of declarative and nondeclarative memory systems.

  1996cited by this paper
• N-methyl-D-aspartate receptors in the basolateral amygdala are required for both acquisition and expression of conditional fear in rats

  1996cited by this paper
• Emotion: systems, cells, synaptic plasticity.

  1996cited by this paper
• Conditioning and ethological models of anxiety disorders: stress-in-dynamic-context anxiety models.

  1996cited by this paper
• Synaptic plasticity in the basolateral amygdala induced by hippocampal formation stimulation in vivo

  1995cited by this paper
• Afferent connections of the medial frontal cortex of the rat. II. Cortical and subcortical afferents

  1995cited by this paper
• The role of the rat hippocampal system in several effects of context in extinction.

  1995influential reference
• Neurotransmission in the rat amygdala related to fear and anxiety

  1994cited by this paper
• A retrieval cue for extinction attenuates response recovery (renewal) caused by a return to the conditioning context.

  1994cited by this paper
• Context, Ambiguity, and Classical Conditioning

  1994influential reference
• Post-traumatic stress disorder in the military veteran.

  1994cited by this paper
• Psychobiologic mechanisms of posttraumatic stress disorder.

  1993cited by this paper
• Selective hippocampal lesions abolish the contextual specificity of latent inhibition and conditioning.

  1993cited by this paper
• Context, time, and memory retrieval in the interference paradigms of Pavlovian learning.

  1993cited by this paper
• A retrieval cue for extinction attenuates spontaneous recovery.

  1993cited by this paper
• Modality-specific retrograde amnesia of fear.

  1992cited by this paper
• Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdala

  1992cited by this paper
• Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning.

  1992cited by this paper
• Conditioning and contextual retrieval in hippocampal rats.

  1991cited by this paper
• Distribution of hippocampal CA1 and subicular efferents in the prefrontal cortex of the rat studied by means of anterograde transport of Phaseolus vulgaris‐leucoagglutinin

  1991cited by this paper
• Contextual Conditioning and Reinstatement of Extinguished Instrumental Responding

  1991cited by this paper
• State-dependent fear extinction with two benzodiazepine tranquilizers.

  1990cited by this paper
• Afferent connections of the medial frontal cortex of the rat. A study using retrograde transport of fluorescent dyes. I. Thalamic afferents.

  1990cited by this paper
• Mechanisms underlying spontaneous recovery in autoshaping.

  1990influential reference
• Evolution of a structured connectionist model of Pavlovian conditioning (AESOP).

  1989cited by this paper
• Slow reacquisition following extinction: Context, encoding, and retrieval mechanisms.

  1989cited by this paper
• Information Processing in Animals: Memory Mechanisms.

  1986cited by this paper
• Analysis of the associative and occasion-setting properties of contexts participating in a Pavlovian discrimination.

  1986cited by this paper
• Effect of context on performance to conditioned stimuli with mixed histories of reinforcement and nonreinforcement.

  1986cited by this paper
• Administration of dexamethasone prior to training blocks ACTH-induced recovery of an extinguished avoidance response.

  1985cited by this paper
• ACTH-induced recovery of extinguished avoidance responding

  1984cited by this paper
• Hippocampectomy disrupts acquisition and retention of learned conditional responding.

  1984cited by this paper
• Differential control by context in the inflation and reinstatement paradigms.

  1984influential reference
• Contextual control of the extinction of conditioned fear: tests for the associative value of the context.

  1983influential reference
• A model for Pavlovian learning: variations in the effectiveness of conditioned but not of unconditioned stimuli.

  1980cited by this paper
• The hippocampus, conditional operations, and cognition

  1980cited by this paper
• Contextual control of the extinction of conditioned fear

  1979cited by this paper
• Role of conditioned contextual stimuli in reinstatement of extinguished fear.

  1979cited by this paper

• Dose-Dependent Dual Effects of Gradient Ionizing Radiation on Neurocognition.

  2026cites this paper
• Dendrimer-Conjugated Glutamine Antagonist, D-TTM020, Ameliorates Brain Immune Dysregulation and Improves Neurobehavioral Deficits in the Mecp2-Deficient Mouse Model

  2026cites this paper
• ApoE Isoform-Dependent Effects on Extinction of Contextual Fear Memory and Passive Avoidance Memory

  2025cites this paper
• Cortico-subcortical networks that determine behavioral memory renewal are redefined by noradrenergic neuromodulation

  2025cites this paper
• Theta-paced stimulation of the thalamic nucleus reuniens entrains mPFC-HPC oscillations and facilitates the acquisition of extinction memories

  2025cites this paper
• Stimulus Contingency and Task Context Encoding within the Anterior Cingulate–Amygdala–Cerebellum Associative Learning Network

  2025cites this paper
• Puberty, sex, and fear extinction retention: A neuroimaging study in youth

  2025cites this paper
• Racial Discrimination and Fear-Based Symptoms: Links to Avoidance Behavior and Hippocampal Activity in Black Youth.

  2025cites this paper
• Hippocampal‐Prelimbic Coupling During Context‐Dependent Extinction Retrieval in Rats

  2025cites this paper
• Icariin enhances contextual fear extinction via modulation of platelet activation and ECM-associated signaling in the hippocampus: A multiomics perspective.

  2025cites this paper
• Effects of ketamine on fear memory extinction: a review of preclinical literature

  2025cites this paper
• Neural Reinstatement of Encoding Context Mediates the Switch between Fear and Extinction Recall.

  2025cites this paper
• Multicomponent Multimethod Assessment of Emotional Change in Psychotherapy Research: Initial Validation of a Neurobehavioral Paradigm

  2025cites this paper
• Using a socially enriched environment test to evaluate the effects of different therapeutic approaches on social behavior in a mouse model of social anxiety disorder.

  2025cites this paper
• Alcohol-Induced Changes in Brain Microstructure: Uncovering Novel Pathophysiological Mechanisms of AUD Using Translational DTI in Humans and Rodents.

  2025cites this paper
• Conditional deletion of TRPC1 channel modulates synaptic plasticity, long term depression, and memory extinction in Fragile X syndrome mice

  2025cites this paper
• A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality

  2025cites this paper
• Pharmacological manipulations of the dorsomedial and dorsolateral striatum during fear extinction have opposing effects on fear renewal

  2024cites this paper
• Projections from thalamic nucleus reuniens to hippocampal CA1 area participate in context fear extinction by affecting extinction-induced molecular remodeling of excitatory synapses

  2024cites this paper
• Amygdalar Excitation of Hippocampal Interneurons Can Lead to Emotion-driven Overgeneralization of Context

  2024cites this paper
• Differential recruitment of brain circuits during fear extinction in non-stressed compared to stress resilient animals

  2024cites this paper
• Dose-dependent effect of acute THC on extinction memory recall and fear renewal: a randomized, double-blind, placebo-controlled study

  2024cites this paper
• Pharmacological manipulations of the dorsomedial and dorsolateral striatum during fear extinction reveal opposing roles in fear renewal.

  2024cites this paper
• A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality

  2024cites this paper
• Projections from thalamic nucleus reuniens to medial septum enable extinction of remote fear memory

  2024cites this paper
• Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex.

  2024cites this paper
• Modifying reaction time tasks parameters in the automated IntelliCage identifies heightened impulsivity and impaired attention in the 3xTg-AD model of Alzheimer’s disease

  2024cites this paper
• Hippocampal Engrams and Contextual Memory.

  2024cites this paper
• Projections from thalamic nucleus reuniens to hippocampal CA1 area enable context value updating

  2024cites this paper
• Sex differences in response inhibition-related neural predictors of PTSD in recent trauma-exposed civilians.

  2024cites this paper
• Deep brain stimulation of the medial forebrain bundle promotes the extinction of active avoidance and is associated with mossy fibber sprouting in the hippocampus.

  2024cites this paper
• The Impact Of The Left Inferior Frontal Gyrus On Fear Extinction: A Transcranial Direct Current Stimulation Study.

  2024cites this paper
• Underlying Hippocampal Mechanism of Posttraumatic Stress Disorder Treatment Outcome: Evidence From Two Clinical Trials

  2023cites this paper
• TrkC Intracellular Signalling in the Brain Fear Network During the Formation of a Contextual Fear Memory

  2023cites this paper
• Increased hippocampal CREB phosphorylation after retrieval of remote contextual fear memories in Carioca High-conditioned Freezing rats.

  2023cites this paper
• The Effect of Transcranial Direct Current and Magnetic Stimulation on Fear Extinction and Return of Fear: A meta-analysis and Systematic Review

  2023cites this paper
• Fear extinction relies on ventral hippocampal safety codes shaped by the amygdala

  2023cites this paper
• Alcohol-induced damage to the fimbria/fornix reduces hippocampal-prefrontal cortex connection during early abstinence

  2023cites this paper
• Hippocampal Involvement in Safety Signal Learning Varies With Anxiety Among Healthy Adults

  2023cites this paper
• Cannabinoid modulation of corticolimbic activation during extinction learning and fear renewal in adults with posttraumatic stress disorder.

  2023cites this paper
• ABA, AAB and ABC renewal with Pavlovian Conditioning of Tentacle Lowering procedure in the snail Cornu aspersum.

  2023cites this paper
• Behavioral pattern separation is associated with neural and electrodermal correlates of context-dependent fear conditioning

  2023cites this paper
• Update on neurobiological mechanisms of fear: illuminating the direction of mechanism exploration and treatment development of trauma and fear-related disorders

  2023cites this paper
• Estrous cycle state-dependent renewal of appetitive behavior recruits unique patterns of Arc mRNA in female rats

  2023cites this paper
• The influence of sleep on fear extinction in trauma-related disorders

  2022cites this paper
• Role of mGlu5 in Persistent Forms of Hippocampal Synaptic Plasticity and the Encoding of Spatial Experience

  2022cites this paper
• Comparison of behavioral and brain indices of fear renewal during a standard vs. novel immersive reality Pavlovian fear extinction paradigm in healthy adults.

  2022cites this paper
• The relationship between recent PTSD secondary to sexual assault, hippocampal volume and resting state functional connectivity in adolescent girls

  2022cites this paper
• Morris Water Maze and Contextual Fear Conditioning Tasks to Evaluate Cognitive Functions Associated With Adult Hippocampal Neurogenesis

  2022influential citation
• The Role of Aberrant Neural Oscillations in the Hippocampal-Medial Prefrontal Cortex Circuit in Neurodevelopmental and Neurological Disorders.

  2022cites this paper
• The Omnipresence of Autonomic Modulation in Health and Disease.

  2022cites this paper
• Comparing Three Extinction Methods to Reduce Fear Expression and Generalization.

  2021influential citation
• Hippocampal activation during contextual fear inhibition related to resilience in the early aftermath of trauma.

  2021cites this paper
• Presynaptic GABAB receptor inhibition sex dependently enhances fear extinction and attenuates fear renewal

  2021cites this paper
• Post-Traumatic Stress Disorder

  2021cites this paper
• Associations of sleep measures with neural activations accompanying fear conditioning and extinction learning and memory in trauma-exposed individuals.

  2021cites this paper
• Thalamic volume and fear extinction interact to predict acute posttraumatic stress severity.

  2021cites this paper
• Hippocampal Inputs in the Prelimbic Cortex Curb Fear after Extinction

  2021cites this paper
• Beyond the hippocampus: the role of parahippocampal-prefrontal communication in context-modulated behavior.

  2021cites this paper
• Neonatal maternal separation affects metabotropic glutamate receptor 5 expression and anxiety‐related behavior of adult rats

  2021cites this paper
• Computational Modeling of Emotion-Motivated Decisions for Continuous Control of Mobile Robots

  2021cites this paper
• Migration-related trauma and mental health among migrant children emigrating from Mexico and Central America to the United States: Effects on developmental neurobiology and implications for policy.

  2021cites this paper
• Input associativity underlies fear memory renewal

  2021cites this paper
• When gut feelings teach the brain to fear pain: Context-dependent activation of the central fear network in a novel interoceptive conditioning paradigm

  2021cites this paper
• Expression patterns of Arc mRNA after renewal of appetitive behavior in female rats

  2021cites this paper
• The Basolateral Amygdala Mediates the Role of Rapid Eye Movement Sleep in Integrating Fear Memory Responses

  2021cites this paper
• Community violence exposure is associated with hippocampus-insula resting state functional connectivity in urban youth.

  2021cites this paper
• The communication of melancholy, grief, and fear in dance with and without music

  2020cites this paper
• Prevalence and Predictors for Post-Traumatic Stress Disorder (PTSD) among Firefighters: A Systematic Review

  2020cites this paper
• Между когнитивностью и нейропатиями: нейровизуализация эффектов ГАМК-ергической модуляции гиппокампа и префронтального неокортекса по нормированным электрограммам мозга

  2020cites this paper
• Functional and neural mechanisms of human fear conditioning:studies in healthy and brain-damaged individuals

  2020cites this paper
• Genetic predictors of hippocampal subfield volume in PTSD cases and trauma-exposed controls

  2020influential citation
• Reframing the Past: Role of Memory Processes in Emotion Regulation

  2020cites this paper
• Learning About Safety: Conditioned Inhibition as a Novel Approach to Fear Reduction Targeting the Developing Brain.

  2020cites this paper
• Between Cognitivity and Neuropathies: Neuroimaging of the Effects of GABAergic Modulation of the Hippocampus and Prefrontal Neocortexis by Normalized Brain Electrograms

  2020cites this paper
• Renewal of conditioned tentacle lowering by circadian contextual cues in snails Cornu aspersum.

  2020cites this paper
• Chronic stress has lasting effects on improved cued discrimination early in extinction

  2020cites this paper
• Amygdalar and hippocampal beta rhythm synchrony during human fear memory retrieval

  2020cites this paper
• Memory engrams: Recalling the past and imagining the future

  2020cites this paper
• Left Inferior Frontal Gyrus Participates in Mediating the Renewal Effect Irrespective of Context Salience

  2020cites this paper
• Theta Oscillations Through Hippocampal/Prefrontal Pathway: Importance in Cognitive Performances

  2020cites this paper
• Extinction learning alters the neural representation of conditioned fear

  2020cites this paper
• Neurokognitive Aspekte des Sprechens über Angst

  2020cites this paper
• Learning task-state representations

  2019cites this paper
• Hippocampal neurogenesis regulates recovery of defensive responses by recruiting threat- and extinction-signalling brain networks

  2019cites this paper
• Nucleus reuniens mediates the extinction of contextual fear conditioning.

  2019cites this paper
• Epigenetics and neurodevelopmental disorders : molecular and behavioural characterisation of an Ehmt1/Glp knockout mouse model

  2019cites this paper
• A protein phosphatase 2A deficit in the hippocampal CA1 area impairs memory extinction

  2019cites this paper
• Fitness and Musical Taste: Do Physically Fit Listeners Prefer More Stressful Music?

  2019cites this paper
• Sex differences in fear extinction.

  2019cites this paper
• Hippocampal subfield volumes and childhood trauma in bipolar disorders.

  2019cites this paper
• Neurocircuitry of Anxiety Disorders

  2019cites this paper
• Ventral hippocampus interacts with prelimbic cortex during inhibition of threat response via learned safety in both mice and humans

  2019influential citation
• Hippocampal Wdr1 Deficit Impairs Learning and Memory by Perturbing F-actin Depolymerization in Mice.

  2019cites this paper
• Hippocampal pattern separation of emotional information determining risk or resilience in individuals exposed to childhood trauma: linking exposure to neurodevelopmental alterations and threat anticipation.

  2019cites this paper
• Maternal nicotine exposure effects on adolescent learning and memory are abolished in alpha(&agr;)2* nicotinic acetylcholine receptor‐null mutant mice

  2018cites this paper
• A mind cleared by walnut oil: The effects of polyunsaturated and saturated fat on extinction learning.

  2018cites this paper
• Chronic treatment with URB597 ameliorates post-stress symptoms in a rat model of PTSD.

  2018cites this paper
• The effect of ketamine on the consolidation and extinction of contextual fear memory

  2018cites this paper
• Circuit Dynamics of Emotional Processing: Insights from Human Intracranial Recordings

  2018cites this paper