N-methyl-D-aspartate receptors in the basolateral amygdala are required for both acquisition and expression of conditional fear in rats

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Behavioral Neuroscience

• Publication date

  1996-12-01

• Fields of study

  Biology, Psychology

• Identifiers
  DOI 10.1037//0735-7044.110.6.1365
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• The Amygdala Minireview and Fear Conditioning : Has the Nut Been Cracked ?

  1997cited by this paper
• Retrograde abolition of conditional fear after excitotoxic lesions in the basolateral amygdala of rats: absence of a temporal gradient.

  1996cited by this paper
• Taste-potentiated odor conditioning: impairment produced by infusion of an N-methyl-D-aspartate antagonist into basolateral amygdala.

  1995cited by this paper
• Emotion: clues from the brain.

  1995cited by this paper
• Fear conditioning enhances short-latency auditory responses of lateral amygdala neurons: parallel recordings in the freely behaving rat.

  1995cited by this paper
• Involvement of the central nucleus and basolateral complex of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli

  1995cited by this paper
• Synaptic plasticity in the basolateral amygdala induced by hippocampal formation stimulation in vivo

  1995cited by this paper
• Acquisition of contextual Pavlovian fear conditioning is blocked by application of an NMDA receptor antagonist D,L-2-amino-5-phosphonovaleric acid to the basolateral amygdala.

  1994cited by this paper
• Intra-amygdala infusion of the N-methyl-D-aspartate receptor antagonist AP5 impairs acquisition but not performance of discriminated approach to an appetitive CS.

  1994cited by this paper
• Pre- and posttraining infusion of N-methyl-D-aspartate receptor antagonists into the amygdala impair memory in an inhibitory avoidance task.

  1994cited by this paper
• Memory of rats with amygdala lesions induced 30 days after footshock-motivated escape training reflects degree of original training.

  1994cited by this paper
• Neurotransmission in the rat amygdala related to fear and anxiety

  1994cited by this paper
• Effects of muscimol applied to the basolateral amygdala on acquisition and expression of contextual fear conditioning in rats.

  1994cited by this paper
• Differential effects of the N-methyl-D-aspartate antagonist DL-2-amino-5-phosphonovalerate on acquisition of fear of auditory and contextual cues.

  1994cited by this paper
• Mechanisms responsible for reduced contextual conditioning with massed unsignaled unconditional stimuli.

  1993cited by this paper
• A synaptic model of memory: long-term potentiation in the hippocampus

  1993cited by this paper
• Associations and Memories: The Role of NMDA Receptors and Long-Term Potentiation

  1993cited by this paper
• Intra-amygdala infusion of the N-methyl-D-aspartate receptor antagonist AP5 blocks acquisition but not expression of fear-potentiated startle to an auditory conditioned stimulus.

  1992influential reference
• Effects of the novel NMDA receptor antagonist, CGP 39551, on field potentials and the induction and expression of LTP in the dentate gyrus in vivo

  1992cited by this paper
• N-methyl-D-aspartate lesions of the lateral and basolateral nuclei of the amygdala block fear-potentiated startle and shock sensitization of startle.

  1992cited by this paper
• Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning.

  1992cited by this paper
• The role of the amygdala in fear and anxiety.

  1992cited by this paper
• Effects of intra-amygdala injections of NMDA receptor antagonists on acquisition and retention of inhibitory avoidance.

  1992influential reference
• Amnesia by post-training infusion of glutamate receptor antagonists into the amygdala, hippocampus, and entorhinal cortex.

  1992cited by this paper
• The amygdala is essential for the expression of conditional hypoalgesia.

  1992cited by this paper
• N-methyl-D-aspartate receptor antagonist APV blocks acquisition but not expression of fear conditioning.

  1991cited by this paper
• Basolateral amygdaloid multi-unit neuronal correlates of discriminative avoidance learning in rabbits.

  1991cited by this paper
• Long‐Term synaptic potentiation in the amygdala

  1990cited by this paper
• Synaptic plasticity in fear conditioning circuits: induction of LTP in the lateral nucleus of the amygdala by stimulation of the medial geniculate body

  1990cited by this paper
• Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala

  1990influential reference
• Tonic activation of NMDA receptors by ambient glutamate enhances excitability of neurons.

  1989cited by this paper
• Long-term synaptic potentiation.

  1988cited by this paper
• Contextual conditioning with massed versus distributed unconditional stimuli in the absence of explicit conditional stimuli.

  1988cited by this paper
• Hebbian synapses in hippocampus.

  1986cited by this paper
• Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

  1983cited by this paper

• Integration of sensory and fear memories in the rat medial temporal lobe

  2025cites this paper
• Chemogenetic activation of an infralimbic cortex to basolateral amygdala projection promotes resistance to acute social defeat stress

  2020cites this paper
• NMDA receptors in the basolateral amygdala mediate acquisition and extinction of an amphetamine conditioned place preference.

  2019cites this paper
• Early memory consolidation window enables drug induced state‐dependent memory

  2019cites this paper
• A Functional Circuit for the Retrieval of Remote Cued Fear Memory

  2018cites this paper
• Effects of Optogenetic inhibition of BLA on Sleep Brief Optogenetic Inhibition of the Basolateral Amygdala in Mice Alters Effects of Stressful Experiences on Rapid Eye Movement Sleep

  2017cites this paper
• Neurobiological mechanisms of state-dependent learning.

  2017cites this paper
• Reorganization of Basolateral Amygdala-Subiculum Circuitry in Mouse Epilepsy Model

  2016cites this paper
• Activation du gyrus dentelé par le noyau supramammillaire au cours du sommeil paradoxal chez le rongeur : étude neuroanatomique et fonctionnelle

  2016cites this paper
• Stress and Fear Extinction

  2016cites this paper
• Contrasting effects of opposite- versus same-sex housing on hormones, behavior and neurogenesis in a eusocial mammal.

  2016cites this paper
• The Role of Actin Cytoskeleton in Memory Formation in Amygdala

  2016cites this paper
• NMDA receptor antagonism disrupts acquisition and retention of the context preexposure facilitation effect in adolescent rats.

  2016cites this paper
• The role of the basolateral amygdala in punishment

  2015cites this paper
• Anxiety and Fear Conditioning, Neural Basis of

  2015cites this paper
• HIPPOCAMPAL FUNCTION AND THE DEVELOPMENTAL NEUROBIOLOGY OF FEAR CONDITIONING

  2015cites this paper
• Role of D1 receptor antagonism in contextual fear learning and memory

  2015cites this paper
• The role of the medial prefrontal cortex in trace fear extinction

  2015influential citation
• Inhibition of the amygdala central nucleus by stimulation of cerebellar output in rats: a putative mechanism for extinction of the conditioned fear response

  2014cites this paper
• Learning and Memory: Basic Mechanisms

  2014cites this paper
• Subcortical and Limbic Attentional Influences

  2014cites this paper
• Sensitive periods in fear learning and memory

  2014cites this paper
• Molecular mechanisms of threat learning in the lateral nucleus of the amygdala.

  2014cites this paper
• Reactivation of an aversive memory modulates learning strategy preference in male rats

  2013cites this paper
• Thy1-Expressing Neurons in the Basolateral Amygdala May Mediate Fear Inhibition

  2013influential citation
• Repeated restraint stress enhances cue-elicited conditioned freezing and impairs acquisition of extinction in an age-dependent manner.

  2013cites this paper
• Neurobiology of Learning and Memory

  2013cites this paper
• Nitric oxide synthesis in the basolateral complex of the amygdala is required for the consolidation and expression of fear potentiated startle but not shock sensitization of the acoustic startle.

  2012cites this paper
• Sleep deprivation impairs emotional memory retrieval in mice: influence of sex.

  2012cites this paper
• Using the conditioned fear stress (CFS) animal model to understand the neurobiological mechanisms and pharmacological treatment of anxiety

  2012cites this paper
• Neural and cellular mechanisms of fear and extinction memory formation.

  2012cites this paper
• Cell-specific expression of calcineurin immunoreactivity within the rat basolateral amygdala complex and colocalization with the neuropeptide Y Y1 receptor.

  2012cites this paper
• Predator-Based Fear Conditioning: A Novel Approach to the Study of the Neurobiology of Memory

  2012cites this paper
• Role of long-term potentiation in mechanism of the conditioned learning

  2011cites this paper
• SP-8203 shows neuroprotective effects and improves cognitive impairment in ischemic brain injury through NMDA receptor.

  2011cites this paper
• Seeking a spotless mind: extinction, deconsolidation, and erasure of fear memory.

  2011cites this paper
• Neural mechanisms of stimulus generalization in auditory fear conditioning

  2011cites this paper
• Molecular mechanisms of fear learning and memory.

  2011cites this paper
• Facilitating influence of stress on the consolidation of fear memory induced by a weak training: reversal by midazolam pretreatment.

  2011cites this paper
• SSR504734, a glycine transporter-1 inhibitor, attenuates acquisition and expression of contextual conditioned fear in rats

  2010cites this paper
• Prenatal ethanol exposure attenuates GABAergic inhibition in basolateral amygdala leading to neuronal hyperexcitability and anxiety-like behavior of adult rat offspring.

  2010cites this paper
• Contextual, but not auditory, fear conditioning is disrupted by neurotoxic selective lesion of the basal nucleus of amygdala in rats.

  2010cites this paper
• Voluntary exercise improves both learning and consolidation of cued conditioned fear in C57 mice.

  2010cites this paper
• D-Cycloserine Augmentation of Cognitive-Behavioral Therapy: Directions for Pilot Research in Pediatric Obsessive-Compulsive Disorder

  2010cites this paper
• NMDA receptor antagonism in the basolateral but not central amygdala blocks the extinction of Pavlovian fear conditioning in rats

  2010cites this paper
• Deep brain stimulation of the amygdala alleviates post-traumatic stress disorder symptoms in a rat model.

  2010cites this paper
• Infusion of the NMDA receptor antagonist, DL-APV, into the basolateral amygdala disrupts learning to fear a novel and a familiar context as well as relearning to fear an extinguished context.

  2009influential citation
• Endocannabinoid system and fear conditioning.

  2009cites this paper
• Emotion antecedents in schizophrenia.

  2009cites this paper
• Distinct Subtypes of Basolateral Amygdala Taste Neurons Reflect Palatability and Reward

  2009cites this paper
• Dissociating space and trace in dorsal and ventral hippocampus

  2009cites this paper
• The amygdala is not necessary for unconditioned stimulus inflation after Pavlovian fear conditioning in rats.

  2009cites this paper
• AMPA receptors in the medial amygdala are critical for establishing a neuroendocrine memory in the female rat

  2009cites this paper
• Toward Animal Models of Post-Traumatic Stress Disorder

  2009cites this paper
• Emotional Learning: Animals

  2008cites this paper
• Intra-amygdaloid infusion of Ginkgo biloba leaf extract (EGb761) facilitates fear-potentiated startle in rats

  2008cites this paper
• Inducible and Selective Erasure of Memories in the Mouse Brain via Chemical-Genetic Manipulation

  2008cites this paper
• Chapter 3.1 Brain mechanisms of Pavlovian and instrumental aversive conditioning

  2008cites this paper
• Effects of pre or posttraining dorsal hippocampus D‐AP5 injection on fear conditioning to tone, background, and foreground context

  2008cites this paper
• 3.24 – Emotional Learning: Animals

  2008cites this paper
• Extended fear conditioning reveals a role for both N-methyl-D-aspartic acid and non-N-methyl-D-aspartic acid receptors in the amygdala in the acquisition of conditioned fear.

  2008influential citation
• An Assessment of Anxiolytic Drug Screening Tests: Hormetic Dose Responses Predominate

  2008cites this paper
• Hippocampal NMDA receptors are necessary for auditory trace fear conditioning measured with conditioned hypoalgesia in rats.

  2008cites this paper
• Neural and molecular mechanisms of fear memory

  2008cites this paper
• Analysis of behavioral constraints and the neuroanatomy of fear to the predator odor trimethylthiazoline: a model for animal phobias.

  2008cites this paper
• Disruption of AMPA Receptor Endocytosis Impairs the Extinction, but not Acquisition of Learned Fear

  2008cites this paper
• Translocation and activation of Rac in the hippocampus during associative contextual fear learning.

  2007cites this paper
• Systemic administration of polyaminergic agents modulate fear conditioning in rats

  2007cites this paper
• Functional internal complexity of amygdala: focus on gene activity mapping after behavioral training and drugs of abuse.

  2007cites this paper
• Transcriptional Regulation of Brain-Derived Neurotrophic Factor in the Amygdala during Consolidation of Fear Memory

  2007cites this paper
• Neurochemistry/neuropharmacology of fear and fear conditioning

  2007cites this paper
• NMDA receptor blockade in the basolateral amygdala disrupts consolidation of stimulus-reward memory and extinction learning during reinstatement of cocaine-seeking in an animal model of relapse.

  2007cites this paper
• Hippocampal involvement in contextual modulation of fear extinction

  2007cites this paper
• Amygdala upregulation of NCAM polysialylation induced by auditory fear conditioning is not required for memory formation, but plays a role in fear extinction.

  2007cites this paper
• Neurobiology of anxiety disorders and implications for treatment.

  2006cites this paper
• Uncontrollable and unpredictable stress with a reminder experience induces long-lasting effects on physiology and behavior: A novel approach to modeling post-traumatic stress disorder in rats

  2006cites this paper
• Amygdaloid GABA, not glutamate neurotransmission or mRNA transcription controls footshock-associated fear arousal in the acoustic startle paradigm.

  2006cites this paper
• Reconsolidation and Extinction of Conditioned Fear: Inhibition and Potentiation

  2006cites this paper
• Hitting Ras where it counts: Ras antagonism in the basolateral amygdala inhibits long‐term fear memory

  2006cites this paper
• Auditory Fear Conditioning and Conditioned Stress Raise NO3– Level in the Amygdala

  2006cites this paper
• Neural circuits and mechanisms involved in Pavlovian fear conditioning: a critical review.

  2006influential citation
• Nitric oxide signalling in the basolateral complex of the amygdala: an extension of NMDA receptor activation during Pavlovian fear conditioning and expression

  2006cites this paper
• Amygdala, Long-term Potentiation, and Fear Conditioning

  2005cites this paper
• The medial amygdala controls the coital access of female rats: a possible involvement of emotional responsiveness.

  2005cites this paper
• Amygdalic levels of dopamine and serotonin rise upon exposure to conditioned fear stress without elevation of glutamate.

  2005cites this paper
• Glutamatergic Systems and Anxiety

  2005cites this paper
• The effect of long context exposure on cued conditioning and c-fos expression in the rat forebrain.

  2005cites this paper
• Trace fear conditioning depends on NMDA receptor activation and protein synthesis within the dorsal hippocampus of mice.

  2005cites this paper
• Role of glutamate ionotropic and benzodiazepine receptors in the ventromedial hypothalamic nucleus on anxiety.

  2005cites this paper
• Facilitation of conditioned fear extinction by d-cycloserine is mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase cascades and requires de novo protein synthesis in basolateral nucleus of amygdala.

  2005cites this paper
• Effects of pre- or post-training entorhinal cortex AP5 injection on fear conditioning.

  2005cites this paper
• Dorsal hippocampus NMDA receptors differentially mediate trace and contextual fear conditioning

  2005cites this paper
• Building and Burying Fear Memories in the Brain

  2005cites this paper
• Stress-induced enhancement of fear learning: an animal model of posttraumatic stress disorder.

  2005cites this paper
• Stress duration modulates the spatiotemporal patterns of spine formation in the basolateral amygdala.

  2005cites this paper
• The neurobiology of conditioned and unconditioned fear: a neurobehavioral system analysis of the amygdala.

  2004cites this paper
• Fear memories induce a switch in stimulus response and signaling mechanisms for long‐term potentiation in the lateral amygdala

  2004cites this paper
• Emotional perseveration: an update on prefrontal-amygdala interactions in fear extinction.

  2004cites this paper
• Effects of complete immunotoxin lesions of the cholinergic basal forebrain on fear conditioning and spatial learning

  2004cites this paper
• Intra-Amygdala Administration of Polyamines Modulates Fear Conditioning in Rats

  2004cites this paper