Regulation of PUMA-α by p53 in cisplatin-induced renal cell apoptosis

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Oncogene

• Publication date

  2006-07-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.onc.1209440
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Increase of Bax/ Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell line.

  2005cited by this paper
• Differential Gender Differences in Ischemic and Nephrotoxic Acute Renal Failure

  2005cited by this paper
• Identification of the functional domain of p21(WAF1/CIP1) that protects cells from cisplatin cytotoxicity.

  2005cited by this paper
• PUMA Couples the Nuclear and Cytoplasmic Proapoptotic Function of p53

  2005cited by this paper
• Suppression of chondrosarcoma cells by 15-deoxy-Delta 12,14-prostaglandin J2 is associated with altered expression of Bax/Bcl-xL and p21.

  2005cited by this paper
• Prospective therapeutic applications of p53 inhibitors.

  2005cited by this paper
• The Pathophysiology of Mitochondrial Cell Death

  2004influential reference
• PPAR-alpha ligand ameliorates acute renal failure by reducing cisplatin-induced increased expression of renal endonuclease G.

  2004cited by this paper
• Role of p53 in cisplatin-induced tubular cell apoptosis: dependence on p53 transcriptional activity.

  2004influential reference
• Minocycline Up-regulates Bcl-2 and Protects against Cell Death in Mitochondria*

  2004influential reference
• Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis

  2004cited by this paper
• Review Cell Death: Critical Control Points Another Line of Evidence for the Importance of Caspases in Cell Death Came From

  2004influential reference
• Gene therapy: how to target the kidney. Promises and pitfalls.

  2004cited by this paper
• Cellular and molecular studies on cisplatin-induced apoptotic cell death in rat kidney

  2004cited by this paper
• Application of decoy oligodeoxynucleotides-based approach to renal diseases.

  2004cited by this paper
• Hypoxia Selection of Death-resistant Cells

  2004influential reference
• Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells.

  2004cited by this paper
• Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death.

  2003cited by this paper
• Puma is an essential mediator of p53-dependent and -independent apoptotic pathways.

  2003cited by this paper
• Inhibition of Bid-induced Apoptosis by Bcl-2

  2003cited by this paper
• Cytochrome P450 2E1 null mice provide novel protection against cisplatin-induced nephrotoxicity and apoptosis.

  2003cited by this paper
• Cisplatin biochemical mechanism of action: from cytotoxicity to induction of cell death through interconnections between apoptotic and necrotic pathways.

  2003cited by this paper
• Apoptosis-resistance of hypoxic cells: multiple factors involved and a role for IAP-2.

  2003cited by this paper
• Cisplatin: mode of cytotoxic action and molecular basis of resistance

  2003cited by this paper
• PUMA mediates the apoptotic response to p53 in colorectal cancer cells

  2003influential reference
• p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa

  2003cited by this paper
• Live or let die: the cell's response to p53

  2002cited by this paper
• Analyzing mitochondrial changes during apoptosis.

  2002cited by this paper
• TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

  2002cited by this paper
• BID regulation by p53 contributes to chemosensitivity

  2002cited by this paper
• Protein Kinase C- (cid:1) and ERK1/2 Mediate Mitochondrial Dysfunction, Decreases in Active Na (cid:2) Transport, and Cisplatin-induced Apoptosis in Renal Cells*

  2002cited by this paper
• Lysosomal cystine storage augments apoptosis in cultured human fibroblasts and renal tubular epithelial cells.

  2002cited by this paper
• Cisplatin-induced renal cell apoptosis: caspase 3-dependent and -independent pathways.

  2002cited by this paper
• Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

  2001cited by this paper
• Breaking the mitochondrial barrier

  2001cited by this paper
• Identification of genes that mediate sensitivity to cisplatin.

  2001cited by this paper
• Telomerase activity and p53-dependent apoptosis in ovarian cancer cells

  2001cited by this paper
• BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.

  2001cited by this paper
• PUMA induces the rapid apoptosis of colorectal cancer cells.

  2001influential reference
• Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells.

  2001cited by this paper
• PUMA, a novel proapoptotic gene, is induced by p53.

  2001influential reference
• Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis.

  2000cited by this paper
• Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis.

  2000cited by this paper
• A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy.

  1999cited by this paper
• Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases.

  1998cited by this paper
• Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure.

  1998cited by this paper
• The Bcl-2 protein family: arbiters of cell survival.

  1998influential reference
• In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity.

  1998cited by this paper
• Bax in Murine Thymus Is a Soluble Monomeric Protein That Displays Differential Detergent-induced Conformations*

  1998cited by this paper
• Immortalization and characterization of proximal tubule cells derived from kidneys of spontaneously hypertensive and normotensive rats.

  1996cited by this paper
• A novel form of Epstein-Barr virus latency in normal B cells in vivo.

  1995cited by this paper

• Chemoprotective Mechanism of Sodium Thiosulfate Against Cisplatin-Induced Nephrotoxicity Is via Renal Hydrogen Sulfide, Arginine/cAMP and NO/cGMP Signaling Pathways

  2025cites this paper
• Timp2-modified gelatinhydroxyphenylpropionic acid hydrogels reverse enhanced scleral recovery and suppress myopia development in mice

  2025cites this paper
• DNMT1 modulation of RASSF1A methylation enhances breast cancer brain metastasis

  2025cites this paper
• MitoQ reducing sevoflurane-induced cognitive dysfunction by modulating mitochondrial dysfunction

  2025cites this paper
• Bone-targeted celastrol nanocarrier suppresses osteoclastogenesis in postmenopausal osteoporosis

  2025cites this paper
• Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma

  2025cites this paper
• Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis

  2024cites this paper
• PU.1 regulation of type 1 dendritic cell function via NF-κB pathway in inhibition of non-small cell lung cancer progression

  2024influential citation
• Unleashing the therapeutic power of verteporfin-eluting stents: modulating YAP signaling to combat carotid artery restenosis and cerebral watershed infarction

  2024cites this paper
• Doxepin as OCT2 inhibitor ameliorates inflammatory response and modulates PI3K/Akt signaling associated with cisplatin-induced nephrotoxicity in rats

  2024cites this paper
• Protective Effect of Memantine on Cisplatin-Induced Ototoxicity: An In Vitro Study

  2024cites this paper
• NOX4-mediated astrocyte ferroptosis in Alzheimer’s disease

  2024cites this paper
• Novel insights into STIM1's role in store-operated calcium entry and its implications for T-cell mediated inflammation in trigeminal neuralgia

  2024cites this paper
• PDCD4-induced oxidative stress through FGR/NF-κB axis in rectal cancer radiotherapy-induced AKI.

  2024cites this paper
• Platinum iodido drugs show potential anti-tumor activity, affecting cancer cell metabolism and inducing ROS and senescence in gastrointestinal cancer cells

  2024cites this paper
• Antitumor activity and targeting p53-PUMA mRNA expression by 5-flurouracil PLGA-lipid polymeric nanoparticles in mouse mammary carcinomas: comparison to free 5-flurouracil

  2023cites this paper
• Limonin ameliorates cisplatin-induced acute liver injury by inhibiting 11β-hydroxysteroid dehydrogenase type 1.

  2023cites this paper
• Transcriptionally activates CCL28 expression to inhibit M2 polarization of macrophages and prevent immune escape in colorectal cancer cells

  2023influential citation
• Pathological consequences of DNA damage in the kidney

  2023cites this paper
• Cytosine–phosphate–guanine oligodeoxynucleotides alleviate radiation-induced kidney injury in cervical cancer by inhibiting DNA damage and oxidative stress through blockade of PARP1/XRCC1 axis

  2023cites this paper
• CD8+ T cell–derived IL-13 increases macrophage IL-10 to resolve neuropathic pain

  2022cites this paper
• Emerging role of tumor suppressor p53 in acute and chronic kidney diseases

  2022cites this paper
• Protective effect of luteolin against chemical and natural toxicants by targeting NF‐κB pathway

  2022cites this paper
• Leonurine attenuates cisplatin nephrotoxicity by suppressing the NLRP3 inflammasome, mitochondrial dysfunction, and endoplasmic reticulum stress

  2022cites this paper
• HIF in Nephrotoxicity during Cisplatin Chemotherapy: Regulation, Function and Therapeutic Potential

  2021cites this paper
• Panduratin A Derivative Protects against Cisplatin-Induced Apoptosis of Renal Proximal Tubular Cells and Kidney Injury in Mice

  2021cites this paper
• Proximal Tubule p53 in Cold Storage/Transplantation-Associated Kidney Injury and Renal Graft Dysfunction

  2021cites this paper
• Protective effect of Phytochemicals against Cisplatin induced Nephrotoxicity

  2021cites this paper
• Protective Effect of Pyxinol, One Active Ingredient of Lichenes on Cisplatin-Induced Nephrotoxicity via Ameliorating DNA Damage Response

  2021cites this paper
• In Vitro Nephrotoxicity Studies of Established and Experimental Platinum-Based Compounds

  2021cites this paper
• Platinum drugs and taxanes: can we overcome resistance?

  2021influential citation
• NAM protects against cisplatin-induced acute kidney injury by suppressing the PARP1/p53 pathway.

  2021cites this paper
• Regulated cell death in cisplatin-induced AKI: Relevance of myo-inositol metabolism.

  2021cites this paper
• Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application of exogenous lycopene.

  2021cites this paper
• Bromamine T (BAT) Exerts Stronger Anti-Cancer Properties than Taurine (Tau)

  2021cites this paper
• Compound C Protects Against Cisplatin-Induced Nephrotoxicity Through Pleiotropic Effects

  2020influential citation
• Vernonia cinerea regenerates tubular epithelial cells in cisplatin induced nephrotoxicity in cancer bearing mice without affecting antitumor activity

  2020cites this paper
• Pioglitazone alleviates cisplatin nephrotoxicity by suppressing mitochondria‐mediated apoptosis via SIRT1/p53 signalling

  2020cites this paper
• Ganoderma lucidum Prevents Cisplatin-Induced Nephrotoxicity through Inhibition of Epidermal Growth Factor Receptor Signaling and Autophagy-Mediated Apoptosis

  2020influential citation
• Inhibition of p53 DNA binding by a small molecule protects mice from radiation toxicity

  2020cites this paper
• Influence of Tumor Suppressor p53 Functioning on the Expression of Antioxidant System Genes under the Action of Cytotoxic Compounds

  2020cites this paper
• Canagliflozin reduces cisplatin uptake and activates Akt to protect against cisplatin-induced nephrotoxicity.

  2020cites this paper
• Renoprotective Effects of a New Free Radical Scavenger, XH-003, against Cisplatin-Induced Nephrotoxicity

  2020cites this paper
• Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade

  2019cites this paper
• Effect of memantine hydrochloride on cisplatin-induced neurobehavioral toxicity in mice

  2019cites this paper
• p53 induces miR‐199a‐3p to suppress mechanistic target of rapamycin activation in cisplatin‐induced acute kidney injury

  2019cites this paper
• Review of alterations in gene expression and apoptotic pathways caused in nephrotoxicity induced by cisplatin.

  2019cites this paper
• Molecular mechanisms of cisplatin-induced nephrotoxicity: a balance on the knife edge between renoprotection and tumor toxicity

  2019cites this paper
• Growth arrest and DNA damage 45γ is required for caspase-dependent renal tubular cell apoptosis

  2019cites this paper
• New Findings in the Signaling Pathways of cis and trans Platinum Iodido Complexes’ Interaction with DNA of Cancer Cells

  2019cites this paper
• Amniotic fluid stem cells ameliorate cisplatin-induced acute renal failure through induction of autophagy and inhibition of apoptosis

  2019cites this paper
• New Insights in the Pathogenesis of Cisplatin-induced Nephrotoxicity

  2019cites this paper
• Henry Ford Health System

  2019cites this paper
• Review of alterations in gene expression and apoptotic pathways caused in nephrotoxicity induced by cisplatin

  2019cites this paper
• Advances in Toxicological Research of the Anticancer Drug Cisplatin.

  2019cites this paper
• Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway

  2019cites this paper
• Long-term Pilocarpine Treatment Improves Salivary Flow in Irradiated Mice

  2019cites this paper
• Berberine protects renal tubular cells against hypoxia/reoxygenation injury via the Sirt1/p53 pathway

  2018cites this paper
• Overexpressed SIRT6 attenuates cisplatin-induced acute kidney injury by inhibiting ERK1/2 signaling.

  2018cites this paper
• Role of food-derived antioxidants against cisplatin induced-nephrotoxicity.

  2018cites this paper
• Cisplatin-Induced Nephrotoxicity in Rats: Modulatory Role of Simvastatin and Rosuvastatin against Apoptosis and Inflammation. -

  2018cites this paper
• Venlafaxine mitigates cisplatin-induced nephrotoxicity via down-regulating apoptotic pathway in rats.

  2018cites this paper
• Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammation.

  2018cites this paper
• Diallyl sulfide alleviates cisplatin‐induced nephrotoxicity in rats via suppressing NF‐κB downstream inflammatory proteins and p53/Puma signalling pathway

  2018cites this paper
• Renoprotective effect of the isoflavonoid biochanin A against cisplatin induced acute kidney injury in mice: Effect on inflammatory burden and p53 apoptosis

  2018cites this paper
• FGF21 is induced in cisplatin nephrotoxicity to protect against kidney tubular cell injury

  2018cites this paper
• Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity.

  2018cites this paper
• ELABELA and an ELABELA Fragment Protect against AKI.

  2017cites this paper
• Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies

  2017cites this paper
• Protective effect of Schisandra chinensis bee pollen extract on liver and kidney injury induced by cisplatin in rats.

  2017cites this paper
• MicroRNA-375 Is Induced in Cisplatin Nephrotoxicity to Repress Hepatocyte Nuclear Factor 1-β*

  2017cites this paper
• Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker‐256 tumor‐bearing rats

  2017cites this paper
• Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI.

  2017cites this paper
• Cell-to-Cell Variation in p53 Dynamics Leads to Fractional Killing.

  2016cites this paper
• Pharmacotherapeutic options for treating adverse effects of Cisplatin chemotherapy

  2016cites this paper
• NLRP3 inflammasome mediates contrast media-induced acute kidney injury by regulating cell apoptosis

  2016cites this paper
• Developing a more clinically-relevant mouse model of cisplatin-induced nephrotoxicity.

  2016cites this paper
• Dichloroacetate Prevents Cisplatin-Induced Nephrotoxicity without Compromising Cisplatin Anticancer Properties.

  2016cites this paper
• An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures.

  2016cites this paper
• Anti-apoptotic and Anti-inflammatory Effects of Olive Leaf Extract Against Cisplatin-induced Nephrotoxicity in Male Rats

  2016cites this paper
• in renal tubular cells mTOR contributes to ER stress and associated apoptosis

  2016cites this paper
• Hydrogen sulfide: A novel nephroprotectant against cisplatin-induced renal toxicity.

  2016cites this paper
• The Restrained Expression of NF-kB in Renal Tissue Ameliorates Folic Acid Induced Acute Kidney Injury in Mice

  2015cites this paper
• Glutamine protects against cisplatin-induced nephrotoxicity by decreasing cisplatin accumulation.

  2015cites this paper
• Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells—Mitochondrial Outer Membrane Permeabilization and Beyond

  2015cites this paper
• The synthesis of sulforaphane analogues and their protection effect against cisplatin induced cytotoxicity in kidney cells.

  2015cites this paper
• Renoprotective effects of angiotensin receptor blocker and stem cells in acute kidney injury: Involvement of inflammatory and apoptotic markers

  2015cites this paper
• mTOR contributes to ER stress and associated apoptosis in renal tubular cells.

  2015cites this paper
• DNA damage response in cisplatin-induced nephrotoxicity

  2015cites this paper
• Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation

  2015cites this paper
• An integrated view of cisplatin-induced nephrotoxicity and ototoxicity.

  2015cites this paper
• Epidermal Growth Factor Receptor Inhibition with Erlotinib Partially Prevents Cisplatin-Induced Nephrotoxicity in Rats

  2014cites this paper
• Knockdown of mutated H-Ras V12 expression induces chemosensitivity of hepatocellular carcinoma cells to cisplatin treatment in vitro and in nude mouse xenografts.

  2014cites this paper
• Combined treatment of canine osteosarcoma cells with gene knock-down and chemotherapy

  2014cites this paper
• Epigallocatechin-3-gallate protects against cisplatin nephrotoxicity by inhibiting the apoptosis in mouse.

  2014cites this paper
• Pathophysiology of Cisplatin-Induced Acute Kidney Injury

  2014cites this paper
• Mitochondrial dysregulation and protection in cisplatin nephrotoxicity

  2014influential citation
• Tubular p53 regulates multiple genes to mediate AKI.

  2014cites this paper
• Farnesoid X Receptor Ligand Prevents Cisplatin-Induced Kidney Injury by Enhancing Small Heterodimer Partner

  2014cites this paper
• Regulated cell death in AKI.

  2014cites this paper