Minor Oral Lesions Facilitate Transmission of Chronic Wasting Disease

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Virology

• Publication date

  2010-11-17

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1128/JVI.01655-10PMID 21084472PMCID PMC3020502
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pathogenesis of chronic wasting disease in cervidized transgenic mice.

  2010cited by this paper
• Asymptomatic deer excrete infectious prions in faeces

  2010cited by this paper
• Aerosol and nasal transmission of chronic wasting disease in cervidized mice

  2010cited by this paper
• Chronic Wasting Disease Prions in Elk Antler Velvet

  2009cited by this paper
• Role of the Lymphoreticular System in Prion Neuroinvasion from the Oral and Nasal Mucosa

  2009cited by this paper
• Detection of CWD Prions in Urine and Saliva of Deer by Transgenic Mouse Bioassay

  2009cited by this paper
• Chronic wasting disease of deer and elk in transgenic mice: oral transmission and pathobiology.

  2007cited by this paper
• Role of the draining lymph node in scrapie agent transmission from the skin.

  2007cited by this paper
• Scrapie Agent (Strain 263K) Can Transmit Disease via the Oral Route after Persistence in Soil over Years

  2007cited by this paper
• Oral Transmissibility of Prion Disease Is Enhanced by Binding to Soil Particles

  2007cited by this paper
• Infectious Prions in the Saliva and Blood of Deer with Chronic Wasting Disease

  2006cited by this paper
• Patterns of PrPCWD accumulation during the course of chronic wasting disease infection in orally inoculated mule deer (Odocoileus hemionus).

  2006cited by this paper
• Oral Transmission of Chronic Wasting Disease in Captive Shira's Moose

  2006cited by this paper
• Preliminary Observations of Genetic Susceptibility of elk (Cervus Elaphus Nelsoni) to Chronic Wasting Disease by Experimental Oral Inoculation

  2006cited by this paper
• Prions Adhere to Soil Minerals and Remain Infectious

  2006cited by this paper
• Extraneural Prion Neuroinvasion without Lymphoreticular System Infection

  2005cited by this paper
• Epidemiology of Chronic Wasting Disease in Captive White-Tailed and Mule Deer

  2004cited by this paper
• Prion Infection of Skeletal Muscle Cells and Papillae in the Tongue

  2004cited by this paper
• Environmental Sources of Prion Transmission in Mule Deer

  2004cited by this paper
• Rapid Prion Neuroinvasion following Tongue Infection

  2003influential reference
• Prion disease: Horizontal prion transmission in mule deer

  2003cited by this paper
• Toxicogenomics: roadblocks and new directions.

  2003cited by this paper
• Prion diseases: infectious and lethal doses following oral challenge.

  2003cited by this paper
• Comparison of Histological Lesions and Immunohistochemical Staining of Proteinase-resistant Prion Protein in a Naturally Occurring Spongiform Encephalopathy of Free-ranging Mule Deer (Odocoileus hemionus) with Those of Chronic Wasting Disease of Captive Mule Deer

  2002cited by this paper
• Oral lesions in sheep and cattle in Dumfries and Galloway.

  2001cited by this paper
• Scrapie infections initiated at varying doses: an analysis of 117 titration experiments.

  2000cited by this paper
• Entry versus Blockade of Brain Infection following Oral or Intraperitoneal Scrapie Administration: Role of Prion Protein Expression in Peripheral Nerves and Spleen

  2000cited by this paper
• Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie.

  2000cited by this paper
• Transmission of the 263K scrapie strain by the dental route.

  1999cited by this paper
• Oral transmission and early lymphoid tropism of chronic wasting disease PrPres in mule deer fawns (Odocoileus hemionus).

  1999cited by this paper
• EPIDEMIOLOGY OF CHRONIC WASTING DISEASE IN CAPTIVE ROCKY MOUNTAIN ELK

  1998cited by this paper
• SPONGIFORM ENCEPHALOPATHY IN FREE-RANGING MULE DEER (ODOCOILEUS HEMIONUS), WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) AND ROCKY MOUNTAIN ELK (CERVUS ELAPHUS NELSONI) IN NORTHCENTRAL COLORADO

  1997cited by this paper
• Scrapie infection can be established readily through skin scarification in immunocompetent but not immunodeficient mice.

  1996cited by this paper
• Pathogenesis of scrapie in mice after intragastric infection.

  1989cited by this paper
• Transmission of scrapie in hamsters.

  1985cited by this paper
• Subviral Pathogens of Plants and Animals: Viroids and Prions

  1985cited by this paper
• Transmission of scrapie by oral route: effect of gingival scarification.

  1982cited by this paper
• Tooth Development and Wear as Criteria of Age in White-Tailed Deer

  1949cited by this paper
• The innervation of the musculature of the tongue.

  1940cited by this paper

• The Evolution of Experimental Rodent Models for Prion Diseases

  2025cites this paper
• Current Biosecurity Practices in the Handling and Sampling of Cervids: A Cross-Sectional Survey.

  2025cites this paper
• New developments in prion disease research using genetically modified mouse models

  2023cites this paper
• Identification of chronic wasting disease prions in decaying tongue tissues from exhumed white-tailed deer

  2023cites this paper
• Transmission, Strain Diversity, and Zoonotic Potential of Chronic Wasting Disease

  2022cites this paper
• Creutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues

  2021cites this paper
• Oxazolone-induced gastrointestinal disorders enhance the oral transmission of AA amyloidosis in mice

  2021cites this paper
• Very low oral exposure to prions of brain or saliva origin can transmit chronic wasting disease

  2020cites this paper
• Oral Ingestion of Synthetically Generated Recombinant Prion Is Sufficient to Cause Prion Disease in Wild-Type Mice

  2020cites this paper
• Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids

  2019cites this paper
• Effect of co-infection with a small intestine-restricted helminth pathogen on oral prion disease pathogenesis in mice

  2019cites this paper
• The role of the immune system in prion infection.

  2018cites this paper
• Immunology of Prion Protein and Prions.

  2017cites this paper
• How will prion disease evolve

  2017cites this paper
• Assessment of Chronic Wasting Disease Prion Shedding in Deer Saliva with Occupancy Modeling

  2017cites this paper
• Pathways of Prion Spread during Early Chronic Wasting Disease in Deer

  2017cites this paper
• How do PrPSc Prions Spread between Host Species, and within Hosts?

  2017cites this paper
• Explorer The influence of commensal and pathogenic gut microbiota on prion disease pathogenesis

  2017cites this paper
• The influence of the commensal and pathogenic gut microbiota on prion disease pathogenesis.

  2016cites this paper
• Using expert judgments to improve chronic wasting disease risk management in Canada

  2016cites this paper
• Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo

  2016cites this paper
• Detection and Quantification of CWD Prions in Fixed Paraffin Embedded Tissues by Real-Time Quaking-Induced Conversion

  2016cites this paper
• Diagnosis of Prion Diseases

  2016cites this paper
• The role of plants as an environmental reservoir of Chronic Wasting Disease prions

  2016cites this paper
• Transmissible Spongiform Encephalopathies

  2016cites this paper
• Immunology of Prion Disease

  2016cites this paper
• Chronic wasting disease of cervids

  2015cites this paper
• Mucosal immunization with an attenuated Salmonella vaccine partially protects white-tailed deer from chronic wasting disease.

  2015cites this paper
• Lesion of the Olfactory Epithelium Accelerates Prion Neuroinvasion and Disease Onset when Prion Replication Is Restricted to Neurons

  2015cites this paper
• The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis

  2015cites this paper
• Quantitative assessment of prion infectivity in tissues and body fluids by real-time quaking-induced conversion.

  2015cites this paper
• Metabolic profiling of prions in the gastro-intestinal tract

  2015cites this paper
• Bovine Spongiform Encephalopathy Mice Overexpressing Deer Prion Protein to Assessing the Susceptibility of Transgenic

  2014cites this paper
• Mucosal transmission and pathogenesis of chronic wasting disease in ferrets.

  2013cites this paper
• Prions and the potential transmissibility of protein misfolding diseases.

  2013cites this paper
• Assessing the Susceptibility of Transgenic Mice Overexpressing Deer Prion Protein to Bovine Spongiform Encephalopathy

  2013cites this paper
• Role of Palatine Tonsils as a Prion Entry Site in Classical and Atypical Experimental Sheep Scrapie

  2013influential citation
• In Vitro Detection of prionemia in TSE-Infected Cervids and Hamsters

  2013cites this paper
• Occurrence, Transmission, and Zoonotic Potential of Chronic Wasting Disease

  2012influential citation
• Aerosol Transmission of Chronic Wasting Disease in White-Tailed Deer

  2012cites this paper
• Molecular Markers of Susceptibility to Prion Diseases in Local Humans and Domesticated Bovids

  2012cites this paper
• Molecular Strain Typing and Environmental Persistence of Ruminant Transmissible Spongiform Encephalopathies

  2012cites this paper
• Time Course of Prion Seeding Activity in Cerebrospinal Fluid of Scrapie-Infected Hamsters after Intratongue and Intracerebral Inoculations

  2012cites this paper
• The diverse roles of mononuclear phagocytes in prion disease pathogenesis

  2012cites this paper
• Susceptibility of Domestic Cats to Chronic Wasting Disease

  2012cites this paper
• DigitalCommons@Th e Texas Medical Center

  2011cites this paper
• An overview of animal prion diseases

  2011cites this paper
• Establishment of bovine prion peptide-based monoclonal antibodies for identifying bovine prion

  2009cites this paper