G. Telling

Leveraging the dominant-negative effect of the kuru-protective G127V prion protein variant as a novel therapeutic strategy
20260 citationsauthor #8
The Evolution of Experimental Rodent Models for Prion Diseases
20259 citationsauthor #2
Enhanced lysosomal activity prevents infection with PrPSc and the seeding activity of α-synuclein & tau prions
20250 citationsauthor #14
Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions
20256 citationsauthor #12
Refined Transgenic Mouse Models Which Recapitulate the Natural Features of Chronic Wasting Disease With Rapid Prion Disease Onsets
20251 citationsauthor #7
Lysosomal Enhancement Prevents Infection with PrPSc, α-Synuclein & Tau Prions
20250 citationsauthor #14
The strain properties of Korean and North American CWD prions are indistinguishable.
20252 citationsauthor #10
Regulated coexpression of PrP from different species in mice impacts the replication and host range properties of prion strains
20250 citationsauthor #10
Conservation of strain properties of bank vole-adapted chronic wasting disease in the absence of glycosylation and membrane anchoring
20250 citationsauthor #9
A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions
202410 citationsauthor #16
Lack of prion transmission barrier in human PrP transgenic Drosophila
20240 citationsauthor #6
Propagation of distinct CWD prion strains during peripheral and intracerebral challenges of gene-targeted mice
20247 citationsauthor #8
Transmission of Norwegian reindeer CWD to sheep by intracerebral inoculation results in an unusual phenotype and prion distribution
20241 citationsauthor #13
Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation
202315 citationsauthor #22
Novel Prion Strain as Cause of Chronic Wasting Disease in a Moose, Finland
202329 citationsauthor #10
Genetic modulation of CWD prion propagation in cervid PrP Drosophila
20233 citationsauthor #6
New developments in prion disease research using genetically modified mouse models
20233 citationsauthor #2
Endoproteolysis of cellular prion protein by plasmin hinders propagation of prions
20222 citationsauthor #3
Tissue-specific biochemical differences between chronic wasting disease prions isolated from free-ranging white-tailed deer (Odocoileus virginianus)
20223 citationsauthor #6
The shape of things to come: structural insights into how prion proteins encipher heritable information
202213 citationsauthor #1
A novel prion strain is responsible for the first case of chronic wasting disease in Finnish moose
20220 citationsauthor #9
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
202211 citationsauthor #20
Adaptive selection of a prion strain conformer corresponding to established North American CWD during propagation of novel emergent Norwegian strains in mice expressing elk or deer prion protein
202145 citationsauthor #25
North American and Norwegian Chronic Wasting Disease prions exhibit different potential for interspecies transmission and zoonotic risk.
202135 citationsauthor #4
Calpastatin Overexpression Protects against Excitotoxic Hippocampal Injury and Traumatic Spinal Cord Injury
20209 citationsauthor #5
The cellular prion protein promotes neuronal regeneration after acute nasotoxic injury
20208 citationsauthor #5
Studies in bank voles reveal strain differences between chronic wasting disease prions from Norway and North America
202077 citationsauthor #14
Incomplete glycosylation during prion infection unmasks a prion protein epitope that facilitates prion detection and strain discrimination
202017 citationsauthor #8
Breakthroughs in antemortem diagnosis of neurodegenerative diseases
20197 citationsauthor #1
In Vitro detection of Chronic Wasting Disease (CWD) prions in semen and reproductive tissues of white tailed deer bucks (Odocoileus virginianus)
201933 citationsauthor #4
Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70)
201924 citationsauthor #8
Role of prion protein glycosylation in replication of human prions by protein misfolding cyclic amplification
201923 citationsauthor #2
Application of PMCA to screen for prion infection in a human cell line used to produce biological therapeutics
20199 citationsauthor #4
Unique Structural Features of Mule Deer Prion Protein Provide Insights into Chronic Wasting Disease
20198 citationsauthor #6
Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies
201928 citationsauthor #21
Primary structural differences at residue 226 of deer and elk PrP dictate selection of distinct CWD prion strains in gene-targeted mice
201956 citationsauthor #8
Scienti fi c opinion on chronic wasting disease ( II ) EFSA Panel on Biological Hazards ( BIOHAZ )
20180 citationsauthor #21
Scientific opinion on chronic wasting disease (II)
201824 citationsauthor #24
Dehydration of Prions on Environmentally Relevant Surfaces Protects Them from Inactivation by Freezing and Thawing
201819 citationsauthor #2
Molecular Mechanisms of Chronic Wasting Disease Prion Propagation.
201824 citationsauthor #2
Comparative analysis of prions in nervous and lymphoid tissues of chronic wasting disease-infected cervids.
201819 citationsauthor #10
The cellular prion protein promotes olfactory sensory neuron survival and axon targeting during adult neurogenesis.
201817 citationsauthor #3
Chronic wasting disease: an evolving prion disease of cervids.
201856 citationsauthor #2
Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency
201735 citationsauthor #7
Explorer Epigenetic dominance of prion conformers
20170 citationsauthor #8
PrPC expression and prion seeding activity in the alimentary tract and lymphoid tissue of deer
201721 citationsauthor #4
Effect of poly-L-arginine in inhibiting scrapie prion protein of cultured cells
20170 citationsauthor #4
Insights into Mechanisms of Transmission and Pathogenesis from Transgenic Mouse Models of Prion Diseases.
201726 citationsauthor #2
Chronic wasting disease prion infection of differentiated neurospheres
20177 citationsauthor #3
Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis
20179 citationsauthor #8
Chronic wasting disease (CWD) in cervids
201770 citationsauthor #24
Prion replication without host adaptation during interspecies transmissions
201754 citationsauthor #14
Effect of poly-L-arginine in inhibiting scrapie prion protein of cultured cells
201713 citationsauthor #4
This information is current as Peripheral Prion Pathogenesis a Soluble Prion Receptor That Potentiates Complement Regulatory Protein Factor H Is
20170 citationsauthor #8
Clay Components in Soil Dictate Environmental Stability and Bioavailability of Cervid Prions in Mice
201626 citationsauthor #9
Insights into Chronic Wasting Disease and Bovine Spongiform Encephalopathy Species Barriers by Use of Real-Time Conversion
201548 citationsauthor #4
Neurodegeneration: Evolved protection against human prions
20151 citationsauthor #1
Repeated cycles of drying and wetting extend the incubation period of prion infection.
20150 citationsauthor #3
Reduced total protein abundance in HY TME brain homogenate.
20150 citationsauthor #3
Mitigation of Prion Infectivity and Conversion Capacity by a Simulated Natural Process—Repeated Cycles of Drying and Wetting
201531 citationsauthor #3
Grass plants bind, retain, uptake, and transport infectious prions.
2015134 citationsauthor #5
Prion disease tempo determined by host-dependent substrate reduction.
201467 citationsauthor #10
Structural effects of PrP polymorphisms on intra- and interspecies prion transmission
201449 citationsauthor #9
Bovine Spongiform Encephalopathy Mice Overexpressing Deer Prion Protein to Assessing the Susceptibility of Transgenic
20140 citationsauthor #20
Quinacrine promotes replication and conformational mutation of chronic wasting disease prions
201456 citationsauthor #3
Intranasal Inoculation of White-Tailed Deer (Odocoileus virginianus) with Lyophilized Chronic Wasting Disease Prion Particulate Complexed to Montmorillonite Clay
201351 citationsauthor #12
Emerging mammalian prions: chronic wasting disease
20130 citationsauthor #1
Brain injury‐induced proteolysis is reduced in a novel calpastatin‐overexpressing transgenic mouse
201332 citationsauthor #4
Assessing the Susceptibility of Transgenic Mice Overexpressing Deer Prion Protein to Bovine Spongiform Encephalopathy
201313 citationsauthor #20
Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease.
201322 citationsauthor #8
Dissociation of Prion Protein Amyloid Seeding from Transmission of a Spongiform Encephalopathy
201325 citationsauthor #3
Epigenetic Dominance of Prion Conformers
201326 citationsauthor #8
Co-existence of Distinct Prion Types Enables Conformational Evolution of Human PrPSc by Competitive Selection*
201348 citationsauthor #9
Chronic Wasting Disease and the Development of Research Models
20136 citationsauthor #1
The Importance of Prions
201310 citationsauthor #1
Enhanced Surveillance Strategies for Detecting and Monitoring Chronic Wasting Disease in Free-Ranging Cervids
201214 citationsauthor #75
DETECTION OF PrPCWD IN FECES FROM NATURALLY EXPOSED ROCKY MOUNTAIN ELK (CERVUS ELAPHUS NELSONI) USING PROTEIN MISFOLDING CYCLIC AMPLIFICATION
201270 citationsauthor #10
Characterization of Conformation-dependent Prion Protein
20121 citationsauthor #14
Small Protease Sensitive Oligomers of PrPSc in Distinct Human Prions Determine Conversion Rate of PrPC
201280 citationsauthor #10
Misfolding and aggregation of PrP in the absence of Prion disease
20121 citationsauthor #3
Characterization of Conformation-dependent Prion Protein Epitopes*
201231 citationsauthor #14
Sensitivity of protein misfolding cyclic amplification versus immunohistochemistry in ante-mortem detection of chronic wasting disease.
201239 citationsauthor #4
Genetic Depletion of Complement Receptors CD21/35 Prevents Terminal Prion Disease in a Mouse Model of Chronic Wasting Disease
201233 citationsauthor #10
Detection of prion protein in the cerebrospinal fluid of elk (Cervus canadensis nelsoni) with chronic wasting disease using protein misfolding cyclic amplification
201222 citationsauthor #5
Incunabular Immunological Events in Prion Trafficking
201233 citationsauthor #9
Conformation-dependent PrP epitopes
20120 citationsauthor #16
Transgenic mouse models and prion strains.
201127 citationsauthor #1
In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells
201124 citationsauthor #8
Generation of a New Form of Human PrPSc in Vitro by Interspecies Transmission from Cervid Prions*
2011116 citationsauthor #2
Prion Protein Expression and Functional Importance in Skeletal Muscle
201117 citationsauthor #6
Chronic wasting disease prion trafficking via the autonomic nervous system.
201129 citationsauthor #3
Detection of Chronic Wasting Disease Prions in Salivary, Urinary, and Intestinal Tissues of Deer: Potential Mechanisms of Prion Shedding and Transmission
2011152 citationsauthor #5
Alteration of the Chronic Wasting Disease Species Barrier by In Vitro Prion Amplification
201128 citationsauthor #5
A schematic representation of common aspects of the procedure that Tanaka and King and Diaz-Avalos used to generate multiple strains by converting Sup35p protein to different aggregating conformations
20110 citationsauthor #1
Unaltered prion protein expression in Alzheimer disease patients
201119 citationsauthor #3
Pathogenesis of chronic wasting disease in cervidized transgenic mice.
201027 citationsauthor #3
Minor Oral Lesions Facilitate Transmission of Chronic Wasting Disease
201047 citationsauthor #2
Reply to Kascsak: Definition of the PrP 3F4 Epitope Revisited
20100 citationsauthor #17
Aerosol and nasal transmission of chronic wasting disease in cervidized mice
201067 citationsauthor #3
Cell-Based Quantification of Chronic Wasting Disease Prions
201079 citationsauthor #6

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