CD81 and Hepatitis C Virus (HCV) Infection

Hepatitis C Virus (HCV) infection is a global public health problem affecting over 160 million individuals worldwide. Its symptoms include chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. HCV is an enveloped RNA virus mainly targeting liver cells and for which the initiation of infection occurs through a complex multistep process involving a series of specific cellular entry factors. This process is likely mediated through the formation of a tightly orchestrated complex of HCV entry factors at the plasma membrane. Among HCV entry factors, the tetraspanin CD81 is one of the best characterized and it is undoubtedly a key player in the HCV lifecycle. In this review, we detail the current knowledge on the involvement of CD81 in the HCV lifecycle, as well as in the immune response to HCV infection.

• Publication year

  2014

• Venue

  Viruses

• Publication date

  2014-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3390/v6020535PMID 24509809PMCID 3939471
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hepatitis C Virus

  2016influential reference
• Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver

  2014cited by this paper
• Critical interaction between E1 and E2 glycoproteins determines binding and fusion properties of hepatitis C virus during cell entry

  2014cited by this paper
• Activated Macrophages Promote Hepatitis C Virus Entry in a Tumor Necrosis Factor-Dependent Manner

  2014cited by this paper
• Impact of single nucleotide polymorphisms in the essential HCV entry factor CD81 on HCV infectivity and neutralization.

  2014cited by this paper
• CD81-Receptor Associations — Impact for Hepatitis C Virus Entry and Antiviral Therapies

  2014cited by this paper
• CD81 sequence and susceptibility to hepatitis C infection

  2014cited by this paper
• Identification of transferrin receptor 1 as a hepatitis C virus entry factor

  2013cited by this paper
• Normal muscle regeneration requires tight control of muscle cell fusion by tetraspanins CD9 and CD81

  2013cited by this paper
• Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36

  2013cited by this paper
• CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of hepatitis C virus–infected cells and induction of interferon‐alpha

  2013influential reference
• Hepatitis C Virus–Infected Cells Downregulate NKp30 and Inhibit Ex Vivo NK Cell Functions

  2013cited by this paper
• EWI‐2wint promotes CD81 clustering that abrogates Hepatitis C Virus entry

  2013cited by this paper
• Cross-linking of CD81 by HCV-E2 protein inhibits human intrahepatic plasmacytoid dendritic cells response to CpG-ODN.

  2013cited by this paper
• The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes*

  2013cited by this paper
• Active RNA Replication of Hepatitis C Virus Downregulates CD81 Expression

  2013cited by this paper
• Completion of the entire hepatitis C virus life-cycle in genetically humanized mice

  2013cited by this paper
• Early infection events highlight the limited transmissibility of hepatitis C virus in vitro.

  2013cited by this paper
• Structural Basis of HCV Neutralization by Human Monoclonal Antibodies Resistant to Viral Neutralization Escape

  2013cited by this paper
• HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex.

  2013cited by this paper
• Different Requirements for Scavenger Receptor Class B Type I in Hepatitis C Virus Cell-Free versus Cell-to-Cell Transmission

  2013cited by this paper
• IFN-γ production by human natural killer cells in response to HCV-infected hepatoma cells is dependent on accessory cells.

  2013influential reference
• Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells

  2013cited by this paper
• Temporal Analysis of Hepatitis C Virus Cell Entry with Occludin Directed Blocking Antibodies

  2013influential reference
• Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

  2013cited by this paper
• Discovery of Cellular Proteins Required for the Early Steps of HCV Infection Using Integrative Genomics

  2013cited by this paper
• The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination

  2013cited by this paper
• Ultrastructural analysis of hepatitis C virus particles

  2013cited by this paper
• HCV and Lymphoproliferation

  2012cited by this paper
• Tetraspanins: gateways for infection.

  2012cited by this paper
• IFITM1 is a tight junction protein that inhibits hepatitis C virus entry†, ‡

  2012cited by this paper
• Hepatoma polarization limits CD81 and hepatitis C virus dynamics

  2012cited by this paper
• Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33

  2012cited by this paper
• Hepatitis C Virus Induces Epidermal Growth Factor Receptor Activation via CD81 Binding for Viral Internalization and Entry

  2012cited by this paper
• Disulfide Bonds in Hepatitis C Virus Glycoprotein E1 Control the Assembly and Entry Functions of E2 Glycoprotein

  2012cited by this paper
• In silico directed mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface

  2012cited by this paper
• Association of the IL28B genotype with insulin resistance in patients with chronic hepatitis C.

  2012cited by this paper
• Distinct roles in folding, CD81 receptor binding and viral entry for conserved histidine residues of hepatitis C virus glycoprotein E1 and E2.

  2012cited by this paper
• Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis

  2012cited by this paper
• Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity.

  2012cited by this paper
• Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1

  2012cited by this paper
• Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody

  2012cited by this paper
• Structural Basis of Ligand Interactions of the Large Extracellular Domain of Tetraspanin CD81

  2012cited by this paper
• Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor

  2011cited by this paper
• Tetraspanins in cellular immunity.

  2011cited by this paper
• A genetically humanized mouse model for hepatitis C virus infection

  2011cited by this paper
• Boceprevir for previously treated chronic HCV genotype 1 infection.

  2011cited by this paper
• Hepatitis C Virus (HCV) Envelope Glycoproteins E1 and E2 Contain Reduced Cysteine Residues Essential for Virus Entry

  2011cited by this paper
• Activation of natural killer cells by hepatitis C virus particles in vitro

  2011cited by this paper
• Hepatitis C Virus Protects Human B Lymphocytes from Fas-Mediated Apoptosis via E2-CD81 Engagement

  2011cited by this paper
• Scavenger receptor class B type I and the hypervariable region-1 of hepatitis C virus in cell entry and neutralisation

  2011cited by this paper
• Impact of Intra- and Interspecies Variation of Occludin on Its Function as Coreceptor for Authentic Hepatitis C Virus Particles

  2011cited by this paper
• ISG56 and IFITM1 Proteins Inhibit Hepatitis C Virus Replication

  2011cited by this paper
• Tetraspanins in the humoral immune response.

  2011cited by this paper
• EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

  2011cited by this paper
• Telaprevir for retreatment of HCV infection.

  2011cited by this paper
• Evolving epidemiology of hepatitis C virus.

  2011cited by this paper
• Mapping a Region of Hepatitis C Virus E2 That Is Responsible for Escape from Neutralizing Antibodies and a Core CD81-Binding Region That Does Not Tolerate Neutralization Escape Mutations

  2011cited by this paper
• Neutralizing Antibody Response to Hepatitis C Virus

  2011cited by this paper
• Mathematical Model of Viral Kinetics In Vitro Estimates the Number of E2-CD81 Complexes Necessary for Hepatitis C Virus Entry

  2011cited by this paper
• Interacting Regions of CD81 and Two of Its Partners, EWI-2 and EWI-2wint, and Their Effect on Hepatitis C Virus Infection*

  2011influential reference
• Assembly of infectious hepatitis C virus particles.

  2011cited by this paper
• The variable regions of hepatitis C virus glycoprotein E2 have an essential structural role in glycoprotein assembly and virion infectivity.

  2011influential reference
• Hepatitis C Virus Is Primed by CD81 Protein for Low pH-dependent Fusion*

  2011cited by this paper
• The Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the Molecule

  2010cited by this paper
• Role of N-Linked Glycans in the Functions of Hepatitis C Virus Envelope Proteins Incorporated into Infectious Virions

  2010cited by this paper
• Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection.

  2010influential reference
• Inhibition of hepatitis C virus infection by anti‐claudin‐1 antibodies is mediated by neutralization of E2–CD81–Claudin‐1 associations

  2010cited by this paper
• Characterization of the Envelope Glycoproteins Associated with Infectious Hepatitis C Virus

  2010cited by this paper
• Novel Function of CD81 in Controlling Hepatitis C Virus Replication

  2010cited by this paper
• Hepatitis C Virus Hypervariable Region 1 Modulates Receptor Interactions, Conceals the CD81 Binding Site, and Protects Conserved Neutralizing Epitopes

  2010cited by this paper
• Plasmacytoid dendritic cells sense hepatitis C virus–infected cells, produce interferon, and inhibit infection

  2010cited by this paper
• Claudin Association with CD81 Defines Hepatitis C Virus Entry

  2010cited by this paper
• Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes.

  2010cited by this paper
• Cell-to-Cell Spread of Retroviruses

  2010cited by this paper
• Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission

  2010cited by this paper
• The second extracellular loop dictates Occludin-mediated HCV entry.

  2010cited by this paper
• Adaptation of Hepatitis C Virus to Mouse CD81 Permits Infection of Mouse Cells in the Absence of Human Entry Factors

  2010influential reference
• Role of lipid metabolism in hepatitis C virus assembly and entry

  2010cited by this paper
• Tupaia CD81, SR-BI, Claudin-1, and Occludin Support Hepatitis C Virus Infection

  2010cited by this paper
• Mutations within a Conserved Region of the Hepatitis C Virus E2 Glycoprotein That Influence Virus-Receptor Interactions and Sensitivity to Neutralizing Antibodies

  2010influential reference
• Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system

  2010cited by this paper
• HIV‐1 Assembly Differentially Alters Dynamics and Partitioning of Tetraspanins and Raft Components

  2010cited by this paper
• Endocytosis and Recycling of Tight Junction Proteins in Inflammation

  2009cited by this paper
• Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains

  2009cited by this paper
• Mutation of juxtamembrane cysteines in the tetraspanin CD81 affects palmitoylation and alters interaction with other proteins at the cell surface.

  2009cited by this paper
• Interaction of hepatitis C virus envelope glycoprotein E2 with the large extracellular loop of tupaia CD81.

  2009cited by this paper
• Natural killer cell function is intact after direct exposure to infectious hepatitis C virions

  2009cited by this paper
• The association of CD81 with tetraspanin-enriched microdomains is not essential for Hepatitis C virus entry

  2009cited by this paper
• Differential Effects of Hepatitis C Virus JFH1 on Human Myeloid and Plasmacytoid Dendritic Cells

  2009cited by this paper
• CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells

  2009cited by this paper
• University of Birmingham Polarization restricts hepatitis C virus entry into HepG2 hepatoma cells.

  2009cited by this paper
• Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

  2009influential reference
• The global burden of hepatitis C

  2009cited by this paper
• Hepatoma Cell Density Promotes Claudin-1 and Scavenger Receptor BI Expression and Hepatitis C Virus Internalization

  2009cited by this paper
• Development and characterization of hepatitis C virus genotype 1‐7 cell culture systems: Role of CD81 and scavenger receptor class B type I and effect of antiviral drugs

  2009cited by this paper
• RNA Interference and Single Particle Tracking Analysis of Hepatitis C Virus Endocytosis

  2009cited by this paper
• Lateral organization of membrane proteins: tetraspanins spin their web.

  2009cited by this paper
• Virus Movements on the Plasma Membrane Support Infection and Transmission between Cells

  2009cited by this paper
• The Tight Junction-Associated Protein Occludin Is Required for a Postbinding Step in Hepatitis C Virus Entry and Infection

  2009cited by this paper

• Structural repertoire of HCV broadly neutralizing antibodies targeting the E2 front layer supersite.

  2026cites this paper
• Native-like soluble E1E2 glycoprotein heterodimers on self-assembling protein nanoparticles for hepatitis C virus vaccine design.

  2026cites this paper
• Native-like soluble E1E2 glycoprotein heterodimers on self-assembling protein nanoparticles for hepatitis C virus vaccine design

  2025cites this paper
• The diagnostic potential of extracellular vesicles in virus-related diseases

  2025cites this paper
• Tetraspanins affect membrane structures and the trafficking of molecular partners: what impact on extracellular vesicles?

  2025cites this paper
• Structural Repertoire of HCV Broadly Neutralizing Antibodies Targeting the E2 Front Layer Supersite

  2025cites this paper
• Migrasomes, critical players in intercellular communication

  2025cites this paper
• The Exosome-Mediated Epigenome: Non-Coding RNA and mRNA-Coding Networks in Microbiome–Cellular Communication, Inflammation, and Tumorigenesis Along the Oral–Gut–Lung Axis

  2025cites this paper
• Epigenetic Mechanisms Involved in Hcv Infection and Human HCC

  2025cites this paper
• pH-antenna residues trigger a large-scale conformational change in the large extracellular loop domain of the CD81 human receptor.

  2025cites this paper
• A game of hide-and-seek: how extracellular vesicles evade the immune system

  2025cites this paper
• Distinctive function of Tetraspanins: Implication in viral infections

  2025cites this paper
• The use of peptides for deciphering the mechanism of EBV, HPV, and HCV invasion of human cells

  2025cites this paper
• Alterations in N-glycosylation of HCV E2 Protein in Children Patients with IFN-RBV Therapy Failure

  2024cites this paper
• Identification of NECTIN1 as a novel restriction factor for flavivirus infection

  2024cites this paper
• The Role of Epigallocatechin Gallate (EGCG) in the Combating and Treat-ment of Sexually Transmitted Viral Infections.

  2024cites this paper
• The role of NF-κB signaling pathway in viral hepatitis and gastroenteritis: pathogenesis and therapeutic applications

  2024cites this paper
• Cold case: COVID-19-triggered type 1 cryoglobulinemia

  2024cites this paper
• Hepatitis C Virus: History and Current Knowledge

  2024cites this paper
• Contemporary Insights into Hepatitis C Virus: A Comprehensive Review

  2024cites this paper
• Hepatitis C Virus Infected Human Megakaryocytes and Platelets: Intra-and Extracellular Evaluation

  2024influential citation
• Target-specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings of the CD81 receptor: a combined in silico and in vivo study

  2023cites this paper
• Hepatitis C virus modified sE2F442NYT as an antigen in candidate vaccine facilitates human immune cell activation

  2023influential citation
• Common carp (Cyprinus carpio) CD81 promoting CyHV-3 virus replication via regulating autophagy and RLRs-interferon signaling pathway.

  2023cites this paper
• A Synopsis of Hepatitis C Virus Treatments and Future Perspectives

  2023cites this paper
• High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

  2023cites this paper
• Association of NK Cells with the Severity of Fibrosis in Patients with Chronic Hepatitis C

  2023cites this paper
• Regions of hepatitis C virus E2 required for membrane association

  2023cites this paper
• CompCorona: A Web Portal for Comparative Analysis of the Host Transcriptome of PBMC and Lung SARS-CoV-2, SARS-CoV, and MERS-CoV

  2023cites this paper
• N6-Methyladenosine-Related Gene Signature Associated With Monocyte Infiltration Is Clinically Significant in Gestational Diabetes Mellitus

  2022cites this paper
• Acacia mangium: A promising plant for isolating anti-hepatitis C virus agents

  2022cites this paper
• Insights into Hepatitis C Virus E2core Interactions with Human Cellular Receptor CD81 at Different pHs from Molecular Simulations.

  2022cites this paper
• High resolution photocatalytic mapping of SARS-CoV-2 Spike protein-host cell membrane interactions

  2022cites this paper
• Tetraspanin-enriched microdomains: The building blocks of migrasomes

  2022cites this paper
• A review on hepatitis C virus: role of viral and host-cellular factors in replication and existing therapeutic strategies

  2022cites this paper
• Natural flavonoids effectively block the CD81 receptor of hepatocytes and inhibit HCV infection: a computational drug development approach

  2022cites this paper
• Solvent-induced allosteric transition of the Hepatitis C virus human cellular receptor CD81 large extracellular loop

  2022cites this paper
• Features of Lipid Metabolism in HCV Infection

  2021cites this paper
• Hepatitis C Virus Epitope Immunodominance and B Cell Repertoire Diversity

  2021cites this paper
• Structure-Based and Rational Design of a Hepatitis C Virus Vaccine

  2021cites this paper
• Hepatitis C virus E2 envelope glycoprotein produced in Nicotiana benthamiana triggers humoral response with virus‐neutralizing activity in vaccinated mice

  2021cites this paper
• Recent Progress on Exosomes in RNA Virus Infection

  2021cites this paper
• Responsive polymer‐assisted 3D cryogel supports Huh7.5 as in vitro hepatitis C virus model and ectopic human hepatic tissue in athymic mice

  2020cites this paper
• Gene Section CD81 (Cluster of Differentiation 81)

  2020cites this paper
• T lymphocyte expression in HCV induced Hepatocellular carcinoma

  2020cites this paper
• Towards the Development of a 3-D Biochip for the Detection of Hepatitis C Virus

  2020cites this paper
• Classical and Deep Learning Paradigms for Detection and Validation of Key Genes of Risky Outcomes of HCV

  2020cites this paper
• Junctional and somatic hypermutation-induced CX4C motif is critical for the recognition of a highly conserved epitope on HCV E2 by a human broadly neutralizing antibody

  2020cites this paper
• A 7-Amino Acid Peptide Mimic from Hepatitis C Virus Hypervariable Region 1 Inhibits Mouse Lung Th9 Cell Differentiation by Blocking CD81 Signaling during Allergic Lung Inflammation

  2020cites this paper
• In Vitro Replication of HCV RNA in Peripheral Blood Mononuclear Cells Isolated from Patients Undergoing Treatment for Hepatitis C Virus Infection

  2020cites this paper
• Alteration of cell junctions during viral infection

  2020cites this paper
• CD81 extracted in SMALP nanodiscs comprises two distinct protein populations within a lipid environment enriched with negatively charged headgroups

  2020cites this paper
• Extracellular vesicles in Inflammatory Skin Disorders: from Pathophysiology to Treatment

  2020cites this paper
• Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines

  2020cites this paper
• Pathogenesis of Viral Hepatitis-Induced Chronic Liver Disease: Role of Extracellular Vesicles

  2020cites this paper
• The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity

  2019cites this paper
• Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies

  2019cites this paper
• Differential interaction strategies of hepatitis c virus genotypes during entry - An in silico investigation of envelope glycoprotein E2 - CD81 interaction.

  2019cites this paper
• VH1-69 antiviral broadly neutralizing antibodies: genetics, structures, and relevance to rational vaccine design.

  2019cites this paper
• Differential Expression of CD43, CD81, and CD200 in Classic Versus Variant Hairy Cell Leukemia

  2019cites this paper
• Characterization of functional determinants in the C-terminal part of hepatitis C virus E1 glycoprotein ectodomain

  2019cites this paper
• Rational design of hepatitis C virus E2 core nanoparticle vaccines

  2019cites this paper
• Clearance of hepatitis C virus is associated with early and potent but narrowly-directed, Envelope-specific antibodies

  2019cites this paper
• The Effects of Chlorpromazine on the Expression of the Tetraspanin Protein CD81 in Neural Cell Lines

  2019cites this paper
• CD81+ Exosomes Play a Pivotal Role in the Establishment of Hepatitis C Persistent Infection and Contribute Toward the Progression of Hepatocellular Carcinoma

  2019cites this paper
• Utjecaj klorpromazina na izražaj CD81 proteina u staničnim linijama središnjeg živčanog sustava

  2019cites this paper
• Dissecting the initial events of human cytomegalovirus cell entry

  2019cites this paper
• Current Progress and Challenges in the Development of a Hepatitis C Virus Vaccine

  2019cites this paper
• Biogenesis of Extracellular Vesicles during Herpes Simplex Virus 1 Infection: Role of the CD63 Tetraspanin

  2018cites this paper
• TM6SF2 Promotes Lipidation and Secretion of Hepatitis C Virus in Infected Hepatocytes.

  2018cites this paper
• Characterization of Dendritic Cell-Derived Extracellular Vesicles During Dengue Virus Infection

  2018cites this paper
• Immunometabolic Effect of Cholesterol in Hepatitis C Infection: Implications in Clinical Management and Antiviral Therapy.

  2018cites this paper
• Correlation of CD81 and SCARB1 polymorphisms on virological responses in Iranian patients with chronic hepatitis C virus genotype 1.

  2018cites this paper
• Tetraspanin Assemblies in Virus Infection

  2018cites this paper
• Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice

  2018cites this paper
• Computational Modeling of Hepatitis C Virus Envelope Glycoprotein Structure and Recognition

  2018cites this paper
• The Neutralizing Face of Hepatitis C Virus E2 Envelope Glycoprotein

  2018cites this paper
• Expression and Function of Tetraspanins and Their Interacting Partners in B Cells

  2018cites this paper
• CD81 Receptor Regions outside the Large Extracellular Loop Determine Hepatitis C Virus Entry into Hepatoma Cells

  2018cites this paper
• THE EXPRESSION OF TETRASPANIN ( CD 81 ) ON B CELLS IN RESPONSE TO INTERFERON THERAPY IN CHRONIC HCV PATIENTS

  2018cites this paper
• Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB

  2018cites this paper
• Deficiencies in the CD19 complex.

  2018cites this paper
• Etude fonctionnelle et structurale de protéines impliquées dans l'invasion des cellules hépatocytaires par les sporozoïtes de Plasmodium

  2017cites this paper
• Strategies to Preclude Hepatitis C Virus Entry

  2017cites this paper
• Étude des réponses humorales chez la femme enceinte infectée par le virus de l’hépatite C : cytotoxicité dépendante des anticorps (ADCC) et réponses neutralisantes

  2017cites this paper
• Therapy of Chronic Hepatitis C in the Era of Nanotechnology: Drug Delivery Systems and Liver Targeting.

  2017cites this paper
• Interplay between hepatitis C virus and lipid metabolism during virus entry and assembly.

  2017cites this paper
• Viral dynamics of persistent hepatitis C virus infection in high-sensitive reporter cells resemble patient's viremia.

  2017cites this paper
• The CD9, CD81, and CD151 EC2 domains bind to the classical RGD-binding site of integrin αvβ3.

  2017cites this paper
• CD81 large extracellular loop-containing fusion proteins with a dominant negative effect on HCV cell spread and replication.

  2017cites this paper
• The specificity of homomeric clustering of CD81 is mediated by its δ‐loop

  2017cites this paper
• The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases

  2017cites this paper
• Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis

  2017cites this paper
• A Sequence in the loop domain of hepatitis C virus E2 protein identified in silico as crucial for the selective binding to human CD81

  2017cites this paper
• Subcellular Trafficking of the Papillomavirus Genome during Initial Infection: The Remarkable Abilities of Minor Capsid Protein L2

  2017cites this paper
• Tetraspanins in infections by human cytomegalo- and papillomaviruses.

  2017cites this paper
• Role of Conserved E 2 Residue W 420 in Receptor Binding and Hepatitis C Virus 1 Infection 2 3

  2016cites this paper
• Role of Conserved E2 Residue W420 in Receptor Binding and Hepatitis C Virus Infection

  2016cites this paper
• Fusion of Enveloped Viruses in Endosomes

  2016cites this paper
• Conception et synthèse de molécules à visée anti-infectieuse selon deux stratégies : le criblage à haut débit et l’approche par fragments

  2016cites this paper