Immunology of hepatitis B virus and hepatitis C virus infection

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Nature reviews. Immunology

• Publication date

  2005-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nri1573PMID 15738952
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• An in vitro model of hepatitis C virion production.

  2005cited by this paper
• Genomic analysis of the host response to hepatitis B virus infection.

  2004cited by this paper
• Hepatitis C Virus Persistence after Spontaneous or Treatment-Induced Resolution of Hepatitis C

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• CD8 Epitope Escape and Reversion in Acute HCV Infection

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• A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen.

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• Neutralizing antibody response during acute and chronic hepatitis C virus infection.

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• Hepatitis C virus kinetics and host responses associated with disease and outcome of infection in chimpanzees

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• CD81 is an entry coreceptor for hepatitis C virus.

  2004cited by this paper
• Hepatitis C virus mutation affects proteasomal epitope processing.

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• Diverse Hepatitis C Virus Glycoproteins Mediate Viral Infection in a CD81-Dependent Manner

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• Hepatitis C virus induces a mutator phenotype: Enhanced mutations of immunoglobulin and protooncogenes

  2004cited by this paper
• Negative Regulation of NK Cell Activities by Inhibitory Receptor CD94/NKG2A Leads to Altered NK Cell-Induced Modulation of Dendritic Cell Functions in Chronic Hepatitis C Virus Infection1

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• An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection

  2004cited by this paper
• A FADD-dependent innate immune mechanism in mammalian cells

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• Presence of functional dendritic cells in patients chronically infected with hepatitis C virus.

  2004cited by this paper
• Cellular Immune Responses to the Hepatitis B Virus Polymerase12

  2004cited by this paper
• Pathogenesis of hepatitis C-associated hepatocellular carcinoma.

  2004cited by this paper
• HLA and NK Cell Inhibitory Receptor Genes in Resolving Hepatitis C Virus Infection

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• Cross-Genotype Immunity to Hepatitis C Virus

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• Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms

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• The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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• Neutralizing antibodies to hepatitis C virus (HCV) in immune globulins derived from anti-HCV-positive plasma.

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• Hepatitis C Virus Core Selectively Suppresses Interleukin-12 Synthesis in Human Macrophages by Interfering with AP-1 Activation*

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• Antiviral CD8‐mediated responses in chronic HCV carriers with HBV superinfection

  2004cited by this paper
• MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.

  2004cited by this paper
• Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection.

  2004cited by this paper
• Evolution of hepatitis B virus during primary infection in humans: transient generation of cytotoxic T-cell mutants.

  2004cited by this paper
• Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers.

  2003cited by this paper
• Hepatic T cells and liver tolerance

  2003cited by this paper
• Suppression of HCV‐specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection

  2003cited by this paper
• Chronic hepatitis C virus infection established and maintained in chimpanzees independent of dendritic cell impairment

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• Kinetics of CD4+ and CD8+ Memory T-Cell Responses during Hepatitis C Virus Rechallenge of Previously Recovered Chimpanzees

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• Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance.

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• Frequent Recovery and Broad Genotype 2 Diversity Characterize Hepatitis C Virus Infection in Ghana, West Africa

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• Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP‐2, with outcome of HCV infection

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• Memory CD8+ T Cells Are Required for Protection from Persistent Hepatitis C Virus Infection

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• IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

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• Infectious Hepatitis C Virus Pseudo-particles Containing Functional E1–E2 Envelope Protein Complexes

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• Hepatitis C Virus Core and Nonstructural Protein 3 Proteins Induce Pro- and Anti-inflammatory Cytokines and Inhibit Dendritic Cell Differentiation1

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• Establishment of B-Cell Lymphoma Cell Lines Persistently Infected with Hepatitis C Virus In Vivo and In Vitro: the Apoptotic Effects of Virus Infection

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• Hepatitis C virus infection: when silence is deception.

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• CD8+ T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection

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• Hepatitis C Virus Core and Nonstructural Protein 3 Proteins Induce Pro- and Anti-inflammatory Cytokines and Inhibit Dendritic Cell Differentiation

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• Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

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• Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B.

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• Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles

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• HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help

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• Natural History and Prognosis of Hepatitis B

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• IKKε and TBK1 are essential components of the IRF3 signaling pathway

  2003cited by this paper
• Natural history of chronic hepatitis C

  2002cited by this paper
• Inaugural Article: Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

  2002cited by this paper
• Expression of Hepatitis C Virus Proteins Induces Distinct Membrane Alterations Including a Candidate Viral Replication Complex

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• Interferon-Regulated Pathways That Control Hepatitis B Virus Replication in Transgenic Mice

  2002cited by this paper
• Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection1

  2002cited by this paper
• Binding of the Hepatitis C Virus Envelope Protein E2 to CD81 Inhibits Natural Killer Cell Functions

  2002cited by this paper
• Protection against persistence of hepatitis C.

  2002cited by this paper
• Virus-Specific CD8+ Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C

  2002cited by this paper
• Genomic analysis of the host response to hepatitis C virus infection

  2002cited by this paper
• Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

  2002cited by this paper
• Inhibition of Hepatitis B Virus Replication by Interferon Requires Proteasome Activity†

  2002cited by this paper
• Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection.

  2002cited by this paper
• Comparative Analysis of Anti-Hepatitis C Virus Activity and Gene Expression Mediated by Alpha, Beta, and Gamma Interferons

  2002cited by this paper
• Inhibition of Natural Killer Cells through Engagement of CD81 by the Major Hepatitis C Virus Envelope Protein

  2002cited by this paper
• Characterization of Nuclear RNases That Cleave Hepatitis B Virus RNA near the La Protein Binding Site

  2001cited by this paper
• The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes.

  2001cited by this paper
• Blocking Chemokine Responsive to γ–2/Interferon (IFN)-γ Inducible Protein and Monokine Induced by IFN-γ Activity In Vivo Reduces the Pathogenetic but not the Antiviral Potential of Hepatitis B Virus–specific Cytotoxic T Lymphocytes

  2001cited by this paper
• Long‐term mortality and morbidity of transfusion‐associated non‐A, non‐B, and type C hepatitis: A National Heart, Lung, and Blood Institute collaborative study

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• Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway.

  2001cited by this paper
• DNA Microarray Analysis of Chimpanzee Liver during Acute Resolving Hepatitis C Virus Infection

  2001cited by this paper
• Lamivudine treatment can overcome cytotoxic T‐cell hyporesponsiveness in chronic hepatitis B: New perspectives for immune therapy

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• Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection.

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• Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection

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• Incidence of hepatitis virus infection and severe liver dysfunction in patients receiving chemotherapy for hematologic malignancies

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• Interferon-α inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway

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• Cutting Edge: Inhibition of Hepatitis B Virus Replication by Activated NK T Cells Does Not Require Inflammatory Cell Recruitment to the Liver1

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• Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection.

  2001cited by this paper
• The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection.

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• Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation.

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• Efficient initiation of HCV RNA replication in cell culture.

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• Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C

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• Nitric Oxide Inhibits Hepatitis B Virus Replication in the Livers of Transgenic Mice

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• The Role of Virus-Specific Cd8+ Cells in Liver Damage and Viral Control during Persistent Hepatitis B Virus Infection

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• Vaccination of Chimpanzees With Plasmid DNA Encoding the Hepatitis C Virus (HCV) Envelope E2 Protein Modified the Infection After Challenge With Homologous Monoclonal HCV

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• The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies.

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• Cellular and humoral immune responses induced by intradermal or intramuscular vaccination with the major hepatitis B surface antigen

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• The lymphoid system in hepatitis C virus infection: autoimmunity, mixed cryoglobulinemia, and Overt B-cell malignancy.

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• Intrahepatic Induction of Alpha/Beta Interferon Eliminates Viral RNA-Containing Capsids in Hepatitis B Virus Transgenic Mice

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• Hepatitis C virus and interferon resistance.

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• The Lymphoid System in Hepatitis C Virus Infection: Autoimmunity, Mixed Cryoglobulinemia, and Overt B-Cell Malignancy

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• Host–Virus Interactions during Malaria Infection in Hepatitis B Virus Transgenic Mice

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• Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo

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• Analysis of Successful Immune Responses in Persons Infected with Hepatitis C Virus

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• Antibodies Against Hepatitis C Virus–Like Particles and Viral Clearance in Acute and Chronic Hepatitis C

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• Relative Sensitivity of Hepatitis B Virus and Other Hepatotropic Viruses to the Antiviral Effects of Cytokines

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• Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line.

  1999cited by this paper
• Toward a surrogate model for hepatitis C virus: An infectious molecular clone of the GB virus-B hepatitis agent.

  1999cited by this paper
• Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals.

  1999cited by this paper
• Viral clearance without destruction of infected cells during acute HBV infection.

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• Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C.

  1999cited by this paper
• Replication of Subgenomic Hepatitis C Virus Rnas in a Hepatoma Cell Line

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