Drug-herb interactions: eliminating toxicity with hard drug design.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Current pharmaceutical design

• Publication date

  2006-11-30

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.2174/138161206779010440PMID 17168768
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Herb-Drug Interactions

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• Hypericin--the facts about a controversial agent.

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• Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.

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• Prediction of herb–drug metabolic interactions: a simulation study

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• Effects of St. John's Wort (Hypericum perforatum) on Tacrolimus Pharmacokinetics in Healthy Volunteers

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• Effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers

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• The Influence of St. John's Wort on the Pharmacokinetics and Protein Binding of Imatinib Mesylate

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• Effect of St John's Wort on imatinib mesylate pharmacokinetics

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  2004cited by this paper
• St John's wort induces both cytochrome P450 3A4–catalyzed sulfoxidation and 2C19–dependent hydroxylation of omeprazole

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• Herbal Modulation of P‐Glycoprotein

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• Effect of St. John's Wort on the Pharmacokinetics of Theophylline in Healthy Volunteers

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• Pharmacogenetics and herb-drug interactions: experience with Ginkgo biloba and omeprazole.

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• The role of multidrug transporters in drug availability, metabolism and toxicity.

  2003cited by this paper
• Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

  2003cited by this paper
• Drug efflux transporters in the CNS.

  2003cited by this paper
• Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism.

  2003cited by this paper
• Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects

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• Impact of St John's wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patients.

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• Interactions of Herbs with Cytochrome P450

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• Methadone maintenance treatment and St. John's Wort - a case report.

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• Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients.

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• Decreased Plasma Levels of Amitriptyline and Its Metabolites on Comedication With an Extract From St. John’s Wort (Hypericum perforatum)

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• The effect of garlic supplements on the pharmacokinetics of saquinavir.

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• Drug transport to the brain: key roles for the efflux pump P-glycoprotein in the blood-brain barrier.

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• Possible serotonin syndrome after combination of buspirone and St John's Wort

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• Effect of Silybin and its congeners on human liver microsomal cytochrome P450 activities

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• Variability in the Content of the Constituents of Hypericum perforatum L. and Some Commercial Extracts

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• Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

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• HERBAL SUPPLEMENTS: A POTENTIAL FOR DRUG INTERACTIONS IN TRANSPLANT RECIPIENTS

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• Saint John's wort: An in vitro analysis of P‐glycoprotein induction due to extended exposure

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• Evaluation of Synaptosomal Uptake Inhibition of most Relevant Constituents of St. John's Wort

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• Effect of vanilloid drugs on gastrointestinal transit in mice

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• Different effects of St John's Wort on the pharmacokinetics of simvastatin and pravastatin

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• Should we be concerned about herbal remedies.

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• Interaction between Warfarin and Danshen (Salvia Miltiorrhiza)

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• The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity

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• Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.

  2001cited by this paper
• Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts.

  2001cited by this paper
• The use of a high-volume screening procedure to assess the effects of dietary flavonoids on human cyp1a1 expression.

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• Interaction between cyclosporine and Hypericum perforatum (St. John's wort) after organ transplantation.

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• Carbamazepine is not a substrate for P-glycoprotein.

  2001cited by this paper
• Drug interaction between St John's wort and nevirapine.

  2001cited by this paper
• Herb-drug interactions.

  2000cited by this paper
• Lack of effect of St John's Wort on carbamazepine pharmacokinetics in healthy volunteers

  2000cited by this paper
• In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model.

  2000cited by this paper
• St John's wort, a herbal antidepressant, activates the steroid X receptor.

  2000cited by this paper
• Indinavir concentrations and St John's wort.

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  2000cited by this paper
• Acute heart transplant rejection due to Saint John's wort.

  2000cited by this paper
• St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor.

  2000cited by this paper
• Mania in a patient receiving testosterone replacement post-orchidectomy taking St John’s wort and sertraline

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• Coma in a patient with Alzheimer's disease taking low dose trazodone and ginkgo biloba

  2000cited by this paper
• Effect of St. John's wort (Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers.

  2000cited by this paper
• Drug interaction of St John's wort with cyclosporin.

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• Potential interactions between alternative therapies and warfarin.

  2000cited by this paper
• Pharmacokinetic-Pharmacodynamic Consequences and Clinical Relevance of Cytochrome P450 3A4 Inhibition

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• Profound drop of cyclosporin A whole blood trough levels caused by St. John's wort (Hypericum perforatum)

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• Influence of dietary components on the gastrointestinal metabolism and transport of drugs.

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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
• Potential Metabolic Interaction between St. John's Wort and Theophylline

  1999cited by this paper

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