The effect of garlic supplements on the pharmacokinetics of saquinavir.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Clinical Infectious Diseases

• Publication date

  2002-01-15

• Fields of study

  Medicine

• Identifiers
  DOI 10.1086/324351PMID 11740713
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic.

  2001cited by this paper
• Indinavir concentrations and St John's wort.

  2000cited by this paper
• Hyperlipidemia associated with HIV protease inhibitor use: pathophysiology, prevalence, risk factors and treatment.

  2000cited by this paper
• Garlic for treating hypercholesterolemia. A meta-analysis of randomized clinical trials.

  2000cited by this paper
• Decreased exposure to saquinavir in HIV-1-infected patients after long-term antiretroviral therapy including ritonavir and saquinavir

  2000cited by this paper
• Fat distribution and metabolic changes in patients with HIV infection.

  1999cited by this paper
• Relationships Between Exposure to Saquinavir Monotherapy and Antiviral Response in HIV-Positive Patients

  1999cited by this paper
• Saquinavir, an HIV protease inhibitor, is transported by P-glycoprotein.

  1998cited by this paper
• Saquinavir soft-gel capsule formulation. A review of its use in patients with HIV infection.

  1998cited by this paper
• Patterns of use, expenditures, and perceived efficacy of complementary and alternative therapies in HIV-infected patients.

  1998cited by this paper
• Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism.

  1997cited by this paper
• Complementary AIDS therapies: the good, the bad and the ugly

  1997cited by this paper
• The Effect of High-Dose Saquinavir on Viral Load and CD4+ T-Cell Counts in HIV-Infected Patients

  1996cited by this paper
• Alterations in hepatic phase I and phase II biotransformation enzymes by garlic oil in rats.

  1992cited by this paper
• Pharmaceutical Statistics: Practical and Clinical Applications

  1985cited by this paper
• Pharmaceutical statistics: Practical and clinical applications

  1984cited by this paper
• United States Pharmacopeia

  1955cited by this paper

• An exploratory evaluation of the interaction risk between herbal products and pharmaceutical medicines used concurrently for disease management in Blantyre, Malawi

  2025cites this paper
• Cracking the Sulfur Code: Garlic Bioactive Molecules as Multi-Target Blueprints for Drug Discovery

  2025cites this paper
• Herb-Drug Interactions: A Critical Exploration in Modern Healthcare Practices

  2025cites this paper
• Artificial Intelligence Models and Tools for the Assessment of Drug–Herb Interactions

  2025cites this paper
• Safety Aspects of Herb Interactions: Current Understanding and Future Prospects.

  2024cites this paper
• Schwarzer Knoblauch

  2024cites this paper
• Pharmacokinetics of herb-drug interactions: Experimental models in Nigeria

  2024cites this paper
• Herbal medicines use among HIV/AIDS patients on antiretroviral therapy and its influence on viral suppression and CD4 count: A survey at a tertiary hospital in Tanzania

  2024cites this paper
• Effect of Oregon grape root extracts on P-glycoprotein mediated transport in in vitro cell lines

  2024cites this paper
• A model of purchase intention of complementary and alternative medicines: the role of social media influencers’ endorsements

  2023cites this paper
• Possible Side Effects of Polyphenols and Their Interactions with Medicines

  2023cites this paper
• Effects of aged garlic and ginkgo biloba extracts on the pharmacokinetics of sofosbuvir in rats

  2022cites this paper
• Potential Inhibitory and Inducing Effects of Triphala Formulation on Cytochrome P450 Enzymes

  2022influential citation
• Frequently Used Allopathic and Traditional Medicine for COVID-19 Treatment and Feasibility of Their Integration

  2022cites this paper
• Interactions of Antiretroviral Drugs with Food, Beverages, Dietary Supplements, and Alcohol: A Systematic Review and Meta-analyses

  2022cites this paper
• Drug Interactions with Food and Beverages

  2022cites this paper
• The Phytochemistry and Pharmacology of Tulbaghia, Allium, Crinum and Cyrtanthus: ‘Talented’ Taxa from the Amaryllidaceae

  2022cites this paper
• Pharmacokinetic Outcomes of the Interactions of Antiretroviral Agents with Food and Supplements: A Systematic Review and Meta-Analysis

  2022influential citation
• Clinical Implications of Herbal Supplements in Conventional Medical Practice: A US Perspective

  2022cites this paper
• Clinical importance of herb–drug interaction

  2022cites this paper
• Anticancer potential of allicin: A review.

  2022cites this paper
• Drug-Food Interactions with a Focus on Mediterranean Diet

  2022cites this paper
• Complementary Medicine: Medications and Supplements

  2021cites this paper
• Amalgamation of in-silico, in-vitro and in-vivo approach to establish glabridin as a potential CYP2E1 inhibitor

  2021cites this paper
• Current perspectives in herbal and conventional drug interactions based on clinical manifestations

  2021cites this paper
• Phytochemicals in cancer treatment

  2021cites this paper
• Interactions between nutraceuticals/nutrients and nutrients and therapeutic drugs

  2021cites this paper
• Drug-nutrition interactions

  2021cites this paper
• Потенциальные взаимодействия лекарственных средств и чеснока

  2021cites this paper
• Herb-drug interactions and toxicity: Underscoring potential mechanisms and forecasting clinically relevant interactions induced by common phytoconstituents via data mining and computational approaches.

  2021cites this paper
• PHARMACODYNAMIC AND PHARMACOKINETIC INTERACTIONS OF HERBS WITH PRESCRIBED DRUGS: A REVIEW

  2021cites this paper
• Concomitant botanical medicine use among patients participating in commercial prostate cancer trials.

  2020cites this paper
• Validation of a HPLC method for quantification of midazolam in rat plasma: Application during a Maytenus ilicifolia-drug interaction study.

  2020cites this paper
• Interactions Between Herbs And Drugs At The Level Of Сytochrome P450

  2020cites this paper
• Invitro Impact of Diallyl Disulphide (Dads) on the Biochemical Components of the Cell Envelope of Staphylococcus Aureus Atcc 25293

  2020cites this paper
• Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

  2020cites this paper
• Effect of a Combined Nutraceutical Supplement on the Lipid Profile of Hypercholesterolemic Men

  2020cites this paper
• The provision of care provided by the pharmacy workforce in relation to complementary medicines in Australia.

  2020cites this paper
• Pharmacokinetic Interactions between Herbal Medicines and Drugs: Their Mechanisms and Clinical Relevance

  2020cites this paper
• Indigenous traditional knowledge of medicinal plants used by herbalists in treating opportunistic infections among people living with HIV/AIDS in Uganda.

  2020cites this paper
• Complementary and Alternative Medicine

  2020cites this paper
• The Clinical Importance of Herb-Drug Interactions and Toxicological Risks of Plants and Herbal Products

  2020cites this paper
• Drug-Nutrition Interactions in Infectious Diseases

  2020cites this paper
• HIV/AIDS

  2020cites this paper
• Interactions between antiretroviral therapy and complementary and alternative medicine: A narrative review.

  2020cites this paper
• Herb-Drug Interactions: Focus on Adverse Drug Reactions and Pharmacovigilance of Herbal Medicines

  2019cites this paper
• Herbal Medications: An Evidence-Based Review

  2019cites this paper
• Herb-Drug Interactions and Hepatotoxicity.

  2019cites this paper
• Understanding the relevance of herb–drug interaction studies with special focus on interplays: a prerequisite for integrative medicine

  2019cites this paper
• Therapeutic Potential of Allicin-Rich Garlic Preparations: Emphasis on Clinical Evidence toward Upcoming Drugs Formulation

  2019cites this paper
• The mechanisms of pharmacokinetic food-drug interactions - A perspective from the UNGAP group.

  2019cites this paper
• How Herbal Drugs Works as an Adjuvant Therapy in HIV Related Opportunistic Infections-A Review on Previous Reviews of Litterateur and Researches

  2019cites this paper
• Prevalence and Factors Associated With Herbal Medicine Use among HIV Positive Patients on Highly Active Antiretroviral Therapy in Selected Hospitals in Nairobi County

  2019cites this paper
• The Importance of Ethnicity Definitions and Pharmacogenomics in Ethnobridging and Pharmacovigilance

  2019cites this paper
• A Systematic Review of Drug Metabolism Studies of Plants With Anticancer Properties: Approaches Applied and Limitations

  2019cites this paper
• Are There Adverse Events after the Use of Sexual Enhancement Nutrition Supplements? A Nationwide Online Survey from Japan

  2019cites this paper
• Nutrition Habits in People Living with HIV/AIDS in Bulgaria: Review of Current Practice and Recommendations

  2019cites this paper
• Screening of antibacterial properties of Garlic (Allium sativum L.) extracts against multidrug resistant diabetic foot ulcer bacteria

  2018cites this paper
• Common interactions between drugs and herbal supplements used in alternative medicine

  2018cites this paper
• A REVIEW ON INTERACTION OF HERBALS WITH ALLOPATHIC MEDICINES

  2018cites this paper
• Interakcije lijekova sa sastavnicama funkcionalne hrane: probiotici, resveratrol i organosumporni spojevi

  2018cites this paper
• Potential Influence of Centrally Acting Herbal Drugs on Transporters at the Blood–Cerebrospinal Fluid Barrier and Blood–Brain Barrier

  2018cites this paper
• Common Herbal Dietary Supplement-Drug Interactions.

  2017cites this paper
• Interactions of Commonly Used Prescription Drugs With Food and Beverages

  2017cites this paper
• Therapeutic Risk and Benefits of Concomitantly Using Herbal Medicines and Conventional Medicines: From the Perspectives of Evidence Based on Randomized Controlled Trials and Clinical Risk Management

  2017cites this paper
• Effect of Garlic, Gingko, and St. John’s Wort Extracts on the Pharmacokinetics of Fexofenadine: A Mechanistic Study

  2017cites this paper
• Drug interactions in HIV treatment: complementary & alternative medicines and over-the-counter products

  2017cites this paper
• Products of plant origin – benefits and the potential risk for the consumer

  2017cites this paper
• Impact of curcumin on the pharmacokinetics of rosuvastatin in rats and dogs based on the conjugated metabolites

  2017cites this paper
• Effects of crude and vinegar-processed Curcumae Rhizoma on the activities of CYP 450 enzymes in rats

  2017cites this paper
• Sub-therapeutic darunavir concentration and garlic consumption; a «Mediterranean» drug-food interaction, about 2 cases

  2017cites this paper
• A Review on the Benefits of Allium sativum on Cancer Prevention

  2017cites this paper
• Effect of Short-Term Concomitant Use of Polyherbal Mixture on the Bioavailability of HIV Protease Inhibitors and Organ Damage in Rats

  2017cites this paper
• Dietary supplement interactions with antiretrovirals: a systematic review

  2017cites this paper
• Toxic Effects as a Result of Herbal Medicine Intake

  2016cites this paper
• Potential risks associated with traditional herbal medicine use in cancer care: A study of Middle Eastern oncology health care professionals

  2016influential citation
• Significant inhibitory impact of dibenzyl trisulfide and extracts of Petiveria alliacea on the activities of major drug-metabolizing enzymes in vitro: An assessment of the potential for medicinal plant-drug interactions.

  2016cites this paper
• Complementary and alternative medicine use among cancer patients in Palestine with special reference to safety-related concerns.

  2016cites this paper
• Interactions between Nutraceuticals/Nutrients and Therapeutic Drugs

  2016cites this paper
• The Role of Metabolizing Enzymes and Transporters in Antiretroviral Therapy.

  2016cites this paper
• Prevalence and Characteristics of CAM Use among People Living with HIV and AIDS in Lebanon: Implications for Patient Care

  2016cites this paper
• HERB-DRUG INTERACTIONS: AN OVERVIEW OF MECHANISMS AND CLINICAL ASPECTS

  2016cites this paper
• Proximate Analysis of Garlic (Allium sativum) Paste Treated with Ascorbic and Citric Acids

  2016cites this paper
• Herbal supplements for health promotion and disease prevention.

  2016cites this paper
• Clinically Relevant Pharmacokinetic Herb-drug Interactions in Antiretroviral Therapy.

  2015cites this paper
• Effects of Nigella sativa, Lepidium sativum and Trigonella foenum-graecum on sildenafil disposition in beagle dogs

  2015cites this paper
• Pharmacokinetic herb-drug interaction study of selected traditional medicines used as complementary and alternative medicine (CAM) for HIV/AIDS

  2015cites this paper
• Interactions Between Antiretrovirals and Natural Health Products

  2015cites this paper
• Evaluation of herb-drug interactions in Nigeria with a focus on medicinal plants used in diabetes management

  2015cites this paper
• Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences

  2015cites this paper
• Garlic I: More Than Just Bad Breath

  2015cites this paper
• sativum L. combinado con warfarina en ratas Wistar

  2015cites this paper
• Antihaemostatic effect of combination of Allium sativum L. ethanol extract and warfarin in Wistar rats

  2015cites this paper
• Impact of Herbal Medicines on Conventional Drugs: An Overview

  2015cites this paper
• Herbal Medications and Vitamin Supplements

  2015cites this paper
• Physicochemical and Sensorial Properties of Garlic (Allium sativum) Paste Treated with Ascorbic and Citric Acids

  2015cites this paper
• Scavenging Activity of Different Garlic Extracts and Garlic Powder and their Antioxidant Effect on Heated Sunflower Oil

  2015cites this paper
• Modulatory actions of o-coumaric acid on carcinogen-activating cytochrome P450 isozymes and the potential for drug interactions in human hepatocarcinoma cells*

  2015cites this paper
• Antimicrobial Spectrum of Allium Species – A Review

  2015cites this paper
• Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway

  2015cites this paper