Evolutionary origins of the purinergic signalling system

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Acta Physiologica

• Publication date

  2009-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1748-1716.2009.01957.xPMID 19222398
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Electrophysiological evidence for an ATP-gated ion channel in the principal cells of the frog skin epithelium

  2014cited by this paper
• Evidence for P2Y-type ATP receptors on the serosal membrane of frog skin epithelium

  2014cited by this paper
• Purinergic signalling in the nervous system: an overview.

  2009influential reference
• Purinergic modulation of human corpus cavernosum relaxation.

  2009cited by this paper
• Purinergic cotransmission

  2009influential reference
• Autonomic neurotransmission: 60 years since sir Henry Dale.

  2009influential reference
• Phylogeny of the SNARE vesicle fusion machinery yields insights into the conservation of the secretory pathway in fungi

  2009cited by this paper
• Purinergic cotransmission

  2009influential reference
• A P2X receptor from the tardigrade species Hypsibius dujardini with fast kinetics and sensitivity to zinc and copper

  2009influential reference
• Signaling at purinergic P2X receptors.

  2009cited by this paper
• P2X receptors and synaptic plasticity.

  2009influential reference
• Modulatory effects of adenosine and adenine nucleotides on different heart preparations of the American lobster, Homarus americanus

  2008cited by this paper
• Effects of extracellular ATP on the physiology of Streptomyces coelicolor A3(2).

  2008cited by this paper
• Similarities between UDP-glucose and adenine nucleotide release in yeast: involvement of the secretory pathway.

  2008cited by this paper
• Kinetics of ATP release and cell volume regulation of hyposmotically challenged goldfish hepatocytes.

  2008cited by this paper
• Mapping of the conserved antigenic domains shared between potato apyrase and parasite ATP diphosphohydrolases: potential application in human parasitic diseases

  2008cited by this paper
• Neurotransmitter localization in the neuroepithelial cells and unipolar neurons of the respiratory tract in the bichir, Polypterus bichir bichir G. ST-HIL.

  2008cited by this paper
• The signaling role of extracellular ATP and its dependence on Ca2+ flux in elicitation of Salvia miltiorrhiza hairy root cultures.

  2008cited by this paper
• P2X7 Receptor Differentially Couples to Distinct Release Pathways for IL-1β in Mouse Macrophage1

  2008cited by this paper
• Permeation Properties of a P2X Receptor in the Green Algae Ostreococcus tauri

  2008influential reference
• Mechanisms of ATP‐ and glutamate‐mediated calcium signaling in white matter astrocytes

  2008cited by this paper
• Volumetric response of vertebrate hepatocytes challenged by osmotic gradients: a theoretical approach.

  2008cited by this paper
• Purinergic signalling: past, present and future.

  2008influential reference
• P2X3 receptor gating near normal body temperature

  2008cited by this paper
• P2X Receptors: Epithelial Ion Channels and Regulators of Salt and Water Transport

  2008cited by this paper
• Giardia lamblia: biochemical characterization of an ecto-ATPase activity.

  2008cited by this paper
• Leishmania-released nucleoside diphosphate kinase prevents ATP-mediated cytolysis of macrophages.

  2008cited by this paper
• Purinergic-mediated Ca2+ influx in Dictyostelium discoideum

  2008influential reference
• Enzymatic Properties of an Ecto-nucleoside Triphosphate Diphosphohydrolase from Legionella pneumophila

  2008cited by this paper
• Adenosine A1 receptor activation mediates NMDA receptor activity in a pertussis toxin-sensitive manner during normoxia but not anoxia in turtle cortical neurons.

  2008cited by this paper
• Purinergic signalling and disorders of the central nervous system

  2008influential reference
• Changes in the control of gastric motor activity during metamorphosis in the amphibian Xenopus laevis, with special emphasis on purinergic mechanisms

  2008cited by this paper
• Ectonucleotidases in the nervous system.

  2008cited by this paper
• Adenylyl Cyclase α and cAMP Signaling Mediate Plasmodium Sporozoite Apical Regulated Exocytosis and Hepatocyte Infection

  2008cited by this paper
• Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors.

  2008cited by this paper
• Expression and function of rat urothelial P2Y receptors.

  2008cited by this paper
• Extracellular nucleotides stimulate Cl- currents in biliary epithelia through receptor-mediated IP3 and Ca2+ release.

  2008cited by this paper
• Concepts of neural nitric oxide-mediated transmission

  2008cited by this paper
• Bioluminescence of the arm light organs of the luminous squid Watasenia scintillans.

  2008influential reference
• The Extracellular Adenosine Deaminase Growth Factor, ADGF/CECR1, Plays a Role in Xenopus Embryogenesis via the Adenosine/P1 Receptor*

  2008cited by this paper
• P2 receptors in the regulation of renal transport mechanisms.

  2008cited by this paper
• Extracellular nucleotide metabolism in Leishmania: influence of adenosine in the establishment of infection.

  2008cited by this paper
• Gap junctions in Malpighian tubules of Aedes aegypti

  2008cited by this paper
• Faculty Opinions recommendation of Extracellular ATP in plants. Visualization, localization, and analysis of physiological significance in growth and signaling.

  2007influential reference
• A Leishmania (L.) amazonensis ATP diphosphohydrolase isoform and potato apyrase share epitopes: antigenicity and correlation with disease progression

  2007cited by this paper
• A Drosophila adenosine receptor activates cAMP and calcium signaling.

  2007cited by this paper
• P2 receptors in cardiovascular regulation and disease

  2007influential reference
• Extracellular ATP Induces Nitric Oxide Production in Tomato Cell Suspensions1

  2007cited by this paper
• Developmental changes of purinergic control of intestinal motor activity during metamorphosis in the African clawed frog, Xenopus laevis.

  2007cited by this paper
• Adenosine triphosphatases of cestodes Bothriocephalus scorpii

  2007cited by this paper
• Comparative expression of p2x receptors and ecto-nucleoside triphosphate diphosphohydrolase 3 in hypocretin and sensory neurons in zebrafish.

  2007cited by this paper
• An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum

  2007cited by this paper
• Purinergic control of the quail rectum: modulation of adenosine 5'-triphosphate-mediated contraction with acetylcholine.

  2007cited by this paper
• GTP avoidance in Tetrahymena thermophila requires tyrosine kinase activity, intracellular calcium, NOS, and guanylyl cyclase

  2007cited by this paper
• Adenylate kinase in sea urchin embryonic cilia.

  2007cited by this paper
• Adenosine receptor‐like molecules and related signaling transduction pathways regulate hemocyte adhesion in abalone (Haliotis diversicolor)

  2007cited by this paper
• Role of the ϵ Subunit of Thermophilic F1-ATPase as a Sensor for ATP*

  2007cited by this paper
• A new series of schistosomicide drugs, the alkylaminoalkanethiosulfuric acids, partially inhibit the activity of Schistosoma mansoni ATP diphosphohydrolase.

  2007cited by this paper
• New iantherans from the marine sponge Ianthella quadrangulata: novel agonists of the P2Y(11) receptor.

  2007cited by this paper
• A novel nucleotide receptor in Xenopus activates the cAMP second messenger pathway

  2007cited by this paper
• Quantal Release of ATP in Mouse Cortex

  2007cited by this paper
• Sequence variation in the genes encoding the major capsid protein, the ATPase, and the RNA polymerase 2 (domain 6) of lymphocystis disease virus isolated from Schlegel's black rockfish, Sebastes schlegelii Hilgendorf.

  2007cited by this paper
• Role of the epsilon subunit of thermophilic F1-ATPase as a sensor for ATP.

  2007cited by this paper
• Endoplasmic reticulum stress exacerbates ischemia‐reperfusion‐induced apoptosis through attenuation of Akt protein synthesis in human choriocarcinoma cells

  2007cited by this paper
• Purinergic (P2) receptor control of lower genitourinary tract function and new avenues for drug action: an overview.

  2007cited by this paper
• The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation

  2007cited by this paper
• Innervation and Neurotransmitter Localization in the Lung of the Nile bichir Polypterus bichir bichir

  2007cited by this paper
• Vascular bed-specific endothelium-dependent vasomomotor relaxation in the hagfish, Myxine glutinosa.

  2007cited by this paper
• Characterization of ATP-gated P2X7 receptors in fish provides new insights into the mechanism of release of the leaderless cytokine interleukin-1 beta.

  2007cited by this paper
• Acute and subchronic copper treatments alter extracellular nucleotide hydrolysis in zebrafish brain membranes.

  2007cited by this paper
• Extracellular ATP: an unexpected role as a signaler in plants.

  2007cited by this paper
• Adenosine metabolism in Toxoplasma gondii: potential targets for chemotherapy.

  2007cited by this paper
• Apyrases (Nucleoside Triphosphate-Diphosphohydrolases) Play a Key Role in Growth Control in Arabidopsis1[W][OA]

  2007influential reference
• Reduced axon sprouting after treatment that diminishes microglia accumulation at lesions in the leech CNS

  2007cited by this paper
• Inhibition of Neutrophil Apoptosis by ATP Is Mediated by the P2Y11 Receptor1

  2007cited by this paper
• Identification of diadenosine triphosphate in Brugia malayi by reverse phase high performance liquid chromatography and MALDI mass spectrometry.

  2007cited by this paper
• Physiology and pathophysiology of purinergic neurotransmission.

  2007influential reference
• Purinergic 2X1 Receptors Mediate Endothelial Dependent Vasodilation to ATP

  2007cited by this paper
• Inhibitory purinergic P2 receptor characterisation in rat distal colon.

  2007cited by this paper
• Evolution of calcium homeostasis: from birth of the first cell to an omnipresent signalling system.

  2007cited by this paper
• Ivermectin potentiates ATP-induced ion currents in cortical neurones: evidence for functional expression of P2X4 receptors?

  2007influential reference
• P2X receptors as regulators of the renal microvasculature.

  2007cited by this paper
• Calcium signaling in lizard red blood cells.

  2007cited by this paper
• Characterization of Schistosoma mansoni ATPDase2 gene, a novel apyrase family member.

  2007cited by this paper
• Malaria Plasmodium agent induces alteration in the head proteome of their Anopheles mosquito host

  2007cited by this paper
• Adenosine inhibits voltage‐dependent Ca2+ influx in cone photoreceptor terminals of the tiger salamander retina

  2007cited by this paper
• Characterization of an ecto-5'-nucleotidase (EC 3.1.3.5) activity in intact trophozoites of Trichomonas gallinae.

  2007cited by this paper
• Trypanosoma brucei brucei: biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities.

  2007cited by this paper
• Identification and characterization of a salivary adenosine deaminase from the sand fly Phlebotomus duboscqi, the vector of Leishmania major in sub-Saharan Africa

  2007cited by this paper
• Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

  2007cited by this paper
• Cloning, molecular characterization and expression of ecto-nucleoside triphosphate diphosphohydrolase-1 from Torpedo electric organ.

  2007cited by this paper
• Inhibition by ATP and activation by ADP in the regulation of flagellar movement in sea urchin sperm.

  2007cited by this paper
• A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family

  2007cited by this paper
• Depressing Effect of Caffeine at Crayfish Neuromuscular Synapses II. Initial Search for Possible Sites of Action

  2007cited by this paper
• Ionic dependence of the velocity of release of ATP from permeabilized cholinergic synaptic vesicles.

  2007cited by this paper
• Purine metabolism in Mycobacterium tuberculosis as a target for drug development.

  2007cited by this paper
• Vesicular release of ATP at central synapses

  2006cited by this paper
• Fragments of ATP synthase mediate plant perception of insect attack.

  2006cited by this paper
• Leishmania amazonensis: Biological and biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities.

  2006cited by this paper
• Purinergic signalling in neuron–glia interactions

  2006cited by this paper

• The Three-Body Problem in Stress Biology: The Balance Between O2, NO, and H2S in the Context of Hans Selye’s Stress Concept

  2025cites this paper
• Jasmonate primes plant responses to extracellular ATP

  2025cites this paper
• Coupling of the energetic and purinergic activities of ATP in ischemic and hypoxic disease states

  2025cites this paper
• Mechanisms of astrocytic and microglial purinergic signaling in homeostatic regulation and implications for neurological disease

  2025cites this paper
• Genetically Encoded Single-Wavelength Sensor with High Specificity for Imaging ATP in Living Cells.

  2025cites this paper
• Peripheral Catecholamine Systems: An Evolutionary Perspective.

  2025cites this paper
• Surface-Enhanced Raman Spectroscopy for Adenine Detection in Five Selected Bacterial Strains Under Stress Conditions

  2025cites this paper
• Cell intrinsic versus cell extrinsic control of plasma cell longevity.

  2025cites this paper
• Structural insight into the self-activation and G-protein coupling of P2Y2 receptor

  2025cites this paper
• Enteric glia and purinergic signaling in health and disease.

  2025cites this paper
• Overview of the role of purinergic signaling and insights into its role in cancer therapy.

  2024cites this paper
• The role of the P2X7 receptor in inactivated SARS-CoV-2-induced lung injury

  2024cites this paper
• Enhancer of Shoot Regeneration 2 (ESR2) regulates pollen maturation and vitality in watermelon (Citrullus lanatus)1

  2024cites this paper
• ATP and glutamate coordinate contractions in the freshwater sponge Ephydatia muelleri

  2024cites this paper
• Design, synthesis and in vitro evaluation of novel sulfonylurea and sulfonylthiourea as ectonucleotidases inhibitors

  2024cites this paper
• Cytokine storm in human monkeypox: A possible involvement of purinergic signaling.

  2024cites this paper
• Research Progress on the Synthesis of Nitrogen-Containing Compounds with Cyanamide as a Building Block

  2023cites this paper
• Purinergic signaling and purine base metabolism at the crossroads between immunity, metabolism, and cancer: A review

  2023cites this paper
• Purinergic Signaling and its Role in the Stem Cell Differentiation.

  2023cites this paper
• Aging is associated with impaired triggering of TRPV3-mediated cutaneous vasodilation: a crucial process for local heat exposure

  2023cites this paper
• P2 receptor-mediated signaling in the physiological and pathological brain: From development to aging and disease.

  2023cites this paper
• Alexei Verkhratsky, the Philosopher of Neuroglia. Preface for the Honorary Issue of Neurochemical Research

  2023cites this paper
• ATP Causes Contraction of Denervated Skeletal Muscles

  2023cites this paper
• Mitochondrial and metabolic features of salugenesis and the healing cycle.

  2023cites this paper
• Synthesis of new sulphonate derivatives containing adamantane and 4-chlorophenyl moieties as nucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors

  2022cites this paper
• The adenosine A2A receptor is a therapeutic target in neurological, heart and oncogenic diseases

  2022cites this paper
• The P2X7 receptor in mood disorders: Emerging target in immunopsychiatry, from bench to bedside.

  2022cites this paper
• AdoR-1 (Adenosine Receptor) Contributes to Protection against Paraquat-Induced Oxidative Stress in Caenorhabditis elegans

  2022cites this paper
• Cell-To-Cell Communication in the Resistance Vasculature.

  2022cites this paper
• P2X7 receptor as the regulator of T-cell function in intestinal barrier disruption

  2022cites this paper
• Adenosine Receptor Signaling in Diseases with Focus on Cancer

  2022cites this paper
• The circadian regulation of extracellular ATP

  2022cites this paper
• Rethinking purinergic concepts and updating the emerging role of P2X7 and P2X4 in amyotrophic lateral sclerosis.

  2022cites this paper
• Exogenous Adenosine Modulates Behaviors and Stress Response in Caenorhabditis elegans

  2022cites this paper
• Activity of Succinate Dehydrogenase in Rabbit Blood Lymphocytes Depends on the Characteristics of the Vibration-Based Impact

  2022cites this paper
• Antagonism of the ATP-gated P2X7 receptor: a potential therapeutic strategy for cancer

  2021cites this paper
• Recent Advances Clarifying the Structure and Function of Plant Apyrases (Nucleoside Triphosphate Diphosphohydrolases)

  2021cites this paper
• The Signalling Effects of Photobiomodulation on Osteoblast Proliferation, Maturation and Differentiation: A Review

  2021cites this paper
• Targeting Purinergic Signaling in the Dynamics of Disease Progression in Sepsis

  2021cites this paper
• Damage-Associated Molecular Patterns (DAMPs) in Plant Innate Immunity: Applying the Danger Model and Evolutionary Perspectives.

  2021cites this paper
• P2Y Receptors for Extracellular Nucleotides: Contributions to Cancer Progression and Therapeutic Implications.

  2021cites this paper
• Purinergic signalling in host innate immune defence against intracellular pathogens.

  2021cites this paper
• [VNUT Is a Therapeutic Target for Type 2 Diabetes and NASH].

  2021cites this paper
• Purinergic signaling in the modulation of redox biology

  2021cites this paper
• The Extracellular NADome Modulates Immune Responses

  2021cites this paper
• Candida Extracellular Nucleotide Metabolism Promotes Neutrophils Extracellular Traps Escape

  2021cites this paper
• Snapshot of Microglial Physiological Functions.

  2021cites this paper
• The P2X7 Receptor in Tumor Immunity

  2021cites this paper
• Structure and function of adenosine receptor heteromers

  2021cites this paper
• Regulation of Microglial Functions by Purinergic Mechanisms in the Healthy and Diseased CNS

  2020cites this paper
• Morphological and Motility Features of the Stable Bleb-Driven Monopodial Form of Entamoeba and Its Importance in Encystation

  2020cites this paper
• Introduction to Purinergic Signaling.

  2020cites this paper
• Recent advances of nucleotide nutrition research in aquaculture: a review

  2020cites this paper
• Physiopathological roles of vesicular nucleotide transporter (VNUT), an essential component for vesicular ATP release.

  2020cites this paper
• ATP signaling in the integrative neural center of Aplysia californica

  2020cites this paper
• In Memoriam Geoffrey Burnstock: Creator of Purinergic Signaling

  2020cites this paper
• Early evolutionary history (from bacteria to hemichordata) of the omnipresent purinergic signalling: A tribute to geoff burnstock inquisitive mind.

  2020cites this paper
• Relationship Between Membrane Vesicles, Extracellular ATP and Biofilm Formation in Antarctic Gram-Negative Bacteria

  2020cites this paper
• Sensory Discrimination of Blood and Floral Nectar by Aedes aegypti Mosquitoes.

  2020cites this paper
• Purinergic signaling in infectious diseases of the central nervous system

  2020cites this paper
• P2X receptors in Aplysia californica: Chemosensory systems, bio-energetic and development

  2020cites this paper
• P2X7 receptor and the NLRP3 inflammasome: partners in crime.

  2020cites this paper
• Unveiling the potential of purinergic signaling in schistosomiasis treatment.

  2020cites this paper
• The integrated physiology of glucose homeostasis: regulation by extracellular and intracellular nucleotide sensors

  2020cites this paper
• Extracellular ATP Signaling in Animals and Plants: Comparison and Contrast

  2019cites this paper
• An Essential and Synergistic Role of Purinergic Signaling in Guided Migration of Corneal Epithelial Cells in Physiological Electric Fields

  2019cites this paper
• Structure, function and techniques of investigation of the P2X7 receptor (P2X7R) in mammalian cells.

  2019cites this paper
• An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity

  2019cites this paper
• Extracellular ATP Regulates the Vesicular Pore Opening in Chromaffin Cells and Increases the Fraction Released During Individual Exocytosis Events.

  2019cites this paper
• Simultaneous Fluorescent Recordings of Extracellular ATP and IntracellularCalcium in Mammalian Cells

  2019influential citation
• Purinergic Signaling in the Vertebrate Olfactory System

  2019cites this paper
• Food recognition in hematophagous insects.

  2019cites this paper
• The 5’-nucleotidase S5nA is dispensable for evasion of phagocytosis and biofilm formation in Streptococcus pyogenes

  2019cites this paper
• Estimation of biological affinity of nitrogen-containing conjugated heterocyclic pharmacophores

  2019cites this paper
• Immobilization of firefly luciferase on the cell plasma membrane as a quantitative biosensor for measurement of ATP in the pericellular space in live mammalian cells

  2019cites this paper
• Purinergic P2X7 Receptor: A Cation Channel Sensitive to Tumor Microenvironment.

  2019cites this paper
• A synthesis of new 7-amino-substituted 4-aminopyrazolo[1,5-a][1,3,5]triazines via a selective three-component triazine ring annulation

  2019cites this paper
• Tinkering with targeting nucleotide signaling for control of intracellular Leishmania parasites.

  2019cites this paper
• Exposure to Whole Body Vibration Impairs the Functional Activity of the Energy Producing System in Rabbit Myocardium

  2019cites this paper
• Astrocytic rather than neuronal P2X7 receptors modulate the function of the tri-synaptic network in the rodent hippocampus.

  2019cites this paper
• Adenosine Promotes Endplate nAChR Channel Activity in Adult Mouse Skeletal Muscle Fibers via Low Affinity P1 Receptors.

  2018cites this paper
• The Elusive P2X7 Macropore.

  2018cites this paper
• A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

  2018cites this paper
• Purinergic Signaling Modulates Survival/Proliferation of Human Dental Pulp Stem Cells

  2018cites this paper
• Role of Ca2+ in Mediating Plant Responses to Extracellular ATP and ADP

  2018cites this paper
• Elevated Pressure Changes the Purinergic System of Microglial Cells

  2018cites this paper
• The salivary hyaluronidase and apyrase of the sand fly Sergentomyia schwetzi (Diptera, Psychodidae).

  2018cites this paper
• Secreted Bacterial Adenosine Deaminase Is an Evolutionary Precursor of Adenosine Deaminase Growth Factor

  2018cites this paper
• Small Molecules Enhance Scaffold-Based Bone Grafts via Purinergic Receptor Signaling in Stem Cells

  2018cites this paper
• ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics.

  2018cites this paper
• The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?

  2018cites this paper
• Phylogenetically persistent purinergic modulation of central pattern generators for breathing in lamprey and mammals

  2017cites this paper
• Extracellular ATP signaling and clinical relevance.

  2017cites this paper
• Extracellular Cyclic AMP/Adenosine Signaling Pathway: A Potential Pharmacological Target for Therapeutic Intervention in Chronic Lymphocytic Leukemia

  2017cites this paper
• P2X7 receptor-sensitivity of astrocytes and neurons in the substantia gelatinosa of organotypic spinal cord slices of the mouse depends on the length of the culture period.

  2017cites this paper
• Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats

  2017cites this paper
• Species Difference in Sensitivity of Human and Mouse P2X7 Receptors to Inhibitory Effects of Divalent Metal Cations.

  2017cites this paper
• A multicomponent reaction of 2-aminoimidazoles: microwave-assisted synthesis of novel 5-aza-7-deaza-adenines

  2017cites this paper
• The Role of P 2 Receptor-Mediated Component in Neurogenic Tone Control of Human Great Saphenous Vein

  2017cites this paper
• The P2X7 Receptor in Infection and Inflammation

  2017cites this paper