Xrx1 controls proliferation and multipotency of retinal progenitors.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Molecular and cellular neurosciences

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S1044-7431(02)00025-8PMID 12595236
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Posttranslational mechanisms control the timing of bHLH function and regulate retinal cell fate.

  2002influential reference
• Cell cycle and cell fate in the nervous system.

  2001cited by this paper
• Math5 is required for retinal ganglion cell and optic nerve formation.

  2001cited by this paper
• Zebrafish genes rx1 and rx2 help define the region of forebrain that gives rise to retina.

  2001cited by this paper
• p27Kip1 and p57Kip2 Regulate Proliferation in Distinct Retinal Progenitor Cell Populations

  2001cited by this paper
• The autoregulation of retinal ganglion cell number.

  2001cited by this paper
• Vertebrate neural cell-fate determination: Lessons from the retina

  2001cited by this paper
• Becoming glial in the neural retina

  2001cited by this paper
• Medaka eyeless is the key factor linking retinal determination and eye growth.

  2001cited by this paper
• Notch signaling in the nervous system. Pieces still missing from the puzzle.

  2000influential reference
• Live or let die - retinal ganglion cell death and survival during development and in the lesioned adult CNS.

  2000cited by this paper
• The conditional medaka mutation eyeless uncouples patterning and morphogenesis of the eye.

  2000cited by this paper
• rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells.

  2000influential reference
• Cloning and expression of xSix3, the Xenopus homologue of murine Six3.

  2000cited by this paper
• Pax6 induces ectopic eyes in a vertebrate.

  1999cited by this paper
• X-ngnr-1 and Xath3 promote ectopic expression of sensory neuron markers in the neurula ectoderm and have distinct inducing properties in the retina.

  1999cited by this paper
• Role of Xrx1 in Xenopus eye and anterior brain development.

  1999influential reference
• p27Xic1, a Cdk inhibitor, promotes the determination of glial cells in Xenopus retina.

  1999cited by this paper
• Notch Signaling : Cell Fate Control and Signal Integration in Development

  1999cited by this paper
• Giant eyes in Xenopus laevis by overexpression of XOptx2.

  1999influential reference
• The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates.

  1999cited by this paper
• Notch signaling: cell fate control and signal integration in development.

  1999cited by this paper
• The genetic sequence of retinal development in the ciliary margin of the Xenopus eye.

  1998cited by this paper
• Molecular recapitulation: the growth of the vertebrate retina.

  1998cited by this paper
• Sequential genesis and determination of cone and rod photoreceptors in Xenopus.

  1998cited by this paper
• A role for the fibroblast growth factor receptor in cell fate decisions in the developing vertebrate retina.

  1998cited by this paper
• Changes in epidermal growth factor receptor expression and competence to generate glia regulate timing and choice of differentiation in the retina.

  1998cited by this paper
• Maintenance of neuroepithelial progenitor cells by Delta-Notch signalling in the embryonic chick retina.

  1997cited by this paper
• Xrxl, a novel Xenopus homeobox gene expressed during eye and pineal gland development

  1997influential reference
• Cellular diversification in the vertebrate retina.

  1997cited by this paper
• The Rx homeobox gene is essential for vertebrate eye development

  1997influential reference
• Xath5 participates in a network of bHLH genes in the developing Xenopus retina.

  1997influential reference
• Bcl-2 promotes regeneration of severed axons in mammalian CNS

  1997cited by this paper
• Regulation of neuronal diversity in the Xenopus retina by Delta signalling

  1997influential reference
• rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina.

  1997cited by this paper
• Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

  1997cited by this paper
• Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system.

  1997cited by this paper
• Postmitotic cells fated to become rod photoreceptors can be respecified by CNTF treatment of the retina.

  1997cited by this paper
• Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina.

  1997cited by this paper
• A developmental timer that regulates apoptosis at the onset of gastrulation.

  1997cited by this paper
• Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta

  1995cited by this paper
• Xotch inhibits cell differentiation in the Xenopus retina.

  1995influential reference
• Identification of a developmental timer regulating the stability of embryonic cyclin A and a new somatic A-type cyclin at gastrulation.

  1995cited by this paper
• In situ Hybridization

  1994cited by this paper
• In situ hybridization: an improved whole-mount method for Xenopus embryos.

  1991cited by this paper
• Cloning by differential screening of a Xenopus cDNA coding for a protein highly homologous to cdc2.

  1991cited by this paper
• Lipofection of cDNAs in the embryonic vertebrate central nervous system.

  1990cited by this paper
• Gene expression in the embryonic nervous system of Xenopus laevis.

  1988influential reference
• Multipotent precursors can give rise to all major cell types of the frog retina.

  1988cited by this paper
• Selective Neuronal Death (Ciba Foundation Symposium 126): edited by Gregory Bock and Maeve O'Connor, John Wiley & Sons, 1987. £27.50 (ix + 271 pages) ISBN 0 471 91092 9

  1987cited by this paper
• Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

  1987cited by this paper
• A common progenitor for neurons and glia persists in rat retina late in development

  1987cited by this paper
• Antibodies against filamentous components in discrete cell types of the mouse retina

  1984influential reference
• A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription.

  1982cited by this paper
• Live or let die?

  1975cited by this paper
• Normal Table of Xenopus Laevis

  1968cited by this paper

• Restorative potential of ciliary body cells in a retinal ganglion cell degeneration model

  2025cites this paper
• Temporal Transcriptomic Profiling of the Developing Xenopus laevis Eye

  2024cites this paper
• Temporal Transcriptomic Profiling of the Developing Xenopus laevis Eye

  2024cites this paper
• Elucidating the framework for specification and determination of the embryonic retina.

  2020cites this paper
• Regulation of development by Rx genes

  2020cites this paper
• The C-terminus of the retinal homeobox (rax) gene product modulates transcription in a context-dependent manner

  2019cites this paper
• The role of the Rx homeobox gene in retinal progenitor proliferation and cell fate specification.

  2018cites this paper
• Retinal Stem Cell Culture On Planar Scaffold For Transplantation In Animal Models Of Retinal Degeneration

  2018cites this paper
• The Role of Rx in Embryonic Retinogenesis: Determining Genetic Influences on Optic Vesicle Formation and Photoreceptor Cell Fate

  2017influential citation
• The Role of Signaling Pathway Integration in Neurogenesis

  2016cites this paper
• Retinal homeobox promotes cell growth, proliferation and survival of mushroom body neuroblasts in the Drosophila brain.

  2016cites this paper
• Noggin 1 overexpression in retinal progenitors affects bipolar cell generation.

  2016cites this paper
• The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis

  2016cites this paper
• Nr2e1 regulates retinal lamination and the development of Müller glia, S-cones, and glycineric amacrine cells during retinogenesis

  2015cites this paper
• Rax regulates hypothalamic tanycyte differentiation and barrier function in mice

  2014cites this paper
• Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.

  2014cites this paper
• Characterization of the Rx1‐dependent transcriptome during early retinal development

  2014cites this paper
• Brief Report: Rx1 Defines Retinal Precursor Identity by Repressing Alternative Fates Through the Activation of TLE2 and Hes4

  2013cites this paper
• Rax Is a Selector Gene for Mediobasal Hypothalamic Cell Types

  2013cites this paper
• Neuronal Diversification Within the Retina: Generation of Crossed and Uncrossed Retinal Ganglion Cells

  2013cites this paper
• An essential role for Rax in retina and neuroendocrine system development

  2012cites this paper
• Régulation transcriptionnelle du facteur de transcription spécifique des bâtonnets, Nrl

  2012cites this paper
• Transcriptional regulation of the rod-specific transcription factor, Nrl

  2012cites this paper
• Coordinating Cell Cycle Exit and Differentiation in the Mammalian Retina and its Dependence on Rb

  2012cites this paper
• Molecular analysis of the amphioxus frontal eye unravels the evolutionary origin of the retina and pigment cells of the vertebrate eye

  2012cites this paper
• The Retinal Homeobox (Rx) gene is necessary for retinal regeneration.

  2011influential citation
• Xenopus Bsx links daily cell cycle rhythms and pineal photoreceptor fate

  2010cites this paper
• The role of cell cycle in retinal development: Cyclin‐dependent kinase inhibitors co‐ordinate cell‐cycle inhibition, cell‐fate determination and differentiation in the developing retina †

  2010cites this paper
• Timing neurogenesis by cell cycle?

  2010cites this paper
• Sumoylation controls retinal progenitor proliferation by repressing cell cycle exit in Xenopus laevis.

  2010cites this paper
• Regulation of photoreceptor gene expression by the retinal homeobox (Rx) gene product.

  2010cites this paper
• Eye field specification in Xenopus laevis.

  2010cites this paper
• The G‐protein‐coupled receptor, GPR84, is important for eye development in Xenopus laevis

  2010cites this paper
• Development and evolution: the case of eye development

  2010cites this paper
• Noggin Elicits Retinal Fate in Xenopus Animal Cap Embryonic Stem Cells

  2009cites this paper
• The role of Xenopus Rx-L in photoreceptor cell determination.

  2009cites this paper
• From progenitors to differentiated cells in the vertebrate retina.

  2009cites this paper
• Molecular regulation of vertebrate retina cell fate.

  2009cites this paper
• Regulation and function of the retinal homeobox (Rx) gene in the developing and regenerating retina of pre-metamorphic X. laevis

  2009influential citation
• Retinal homeobox 1 is required for retinal neurogenesis and photoreceptor differentiation in embryonic zebrafish.

  2009cites this paper
• A role for Xvax2 in controlling proliferation of Xenopus ventral eye and brain progenitors

  2008cites this paper
• Dicer inactivation causes heterochronic retinogenesis in Xenopus laevis.

  2008cites this paper
• Proliferative and cell fate effects of Hedgehog signaling in the vertebrate retina.

  2008cites this paper
• Psf2 plays important roles in normal eye development in Xenopus laevis

  2008cites this paper
• A zebrafish LMO4 ortholog limits the size of the forebrain and eyes through negative regulation of six3b and rx3.

  2007cites this paper
• Alterations of rx1 and pax6 expression levels at neural plate stages differentially affect the production of retinal cell types and maintenance of retinal stem cell qualities.

  2007cites this paper
• Mutational and expression analysis of CDK1, cyclinA2 and cyclinB1 in epilepsy‐associated glioneuronal lesions

  2007cites this paper
• Changes in Rx1 and Pax6 activity at eye field stages differentially alter the production of amacrine neurotransmitter subtypes in Xenopus

  2007cites this paper
• A specific box switches the cell fate determining activity of XOTX2 and XOTX5b in the Xenopus retina

  2007cites this paper
• Nucleosome regulator Xhmgb3 is required for cell proliferation of the eye and brain as a downstream target of Xenopus rax/Rx1.

  2006cites this paper
• Dystroglycan is required for proper retinal layering.

  2006cites this paper
• Timing the Generation of Distinct Retinal Cells by Homeobox Proteins

  2006influential citation
• Segregation of telencephalic and eye-field identities inside the zebrafish forebrain territory is controlled by Rx3

  2006cites this paper
• 5-HT2B-mediated serotonin signaling is required for eye morphogenesis in Xenopus.

  2005cites this paper
• Genetic analysis of metamorphic and premetamorphic Xenopus ciliary marginal zone

  2005cites this paper
• Conditional alleles for activation and inactivation of the mouse Rx homeobox gene

  2005cites this paper
• Cell cycle control by homeobox genes in development and disease.

  2005cites this paper
• The role of combinational coding by homeodomain and bHLH transcription factors in retinal cell fate specification.

  2005cites this paper
• chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis.

  2005cites this paper
• Expression of FoxE4 and Rx Visualizes the Timing and Dynamics of Critical Processes Taking Place during Initial Stages of Vertebrate Eye Development

  2005cites this paper
• Xenopus aristaless‐related homeobox (xARX) gene product functions as both a transcriptional activator and repressor in forebrain development

  2005cites this paper
• Organizing the Eye

  2004cites this paper
• Retinal stem cells in vertebrates: parallels and divergences.

  2004cites this paper
• Cell-intrinsic regulators of proliferation in vertebrate retinal progenitors.

  2004cites this paper
• Regulation of vertebrate eye development by Rx genes.

  2004cites this paper
• Mutations in the human RAX homeobox gene in a patient with anophthalmia and sclerocornea.

  2003cites this paper
• Glial Cells Generate Neurons—Master Control within CNS Regions: Developmental Perspectives on Neural Stem Cells

  2003cites this paper
• Regulation of development by Rx genes Regulation of development by Rx genes

  year unknowncites this paper