Long-Term Relationships between Synaptic Tenacity, Synaptic Remodeling, and Network Activity

Amir Minerbi,R. Kahana,Larissa Goldfeld,Maya Kaufman,Shimon Marom,N. Ziv

Published 2009 in PLoS Biology

ABSTRACT

Long term time-lapse imaging reveals that individual synapses undergo significant structural remodeling not only when driven by activity, but also when network activity is absent, raising questions about how reliably individual synapses maintain connections.

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