Reactive Oxygen Species in Vascular Formation and Development

Reactive oxygen species (ROS) are derived from the metabolism of oxygen and are traditionally viewed as toxic byproducts that cause damage to biomolecules. It is now becoming widely acknowledged that ROS are key modulators in a variety of biological processes and pathological states. ROS mediate key signaling transduction pathways by reversible oxidation of certain signaling components and are involved in the signaling of growth factors, G-protein-coupled receptors, Notch, and Wnt and its downstream cascades including MAPK, JAK-STAT, NF-κB, and PI3K/AKT. Vascular formation and development is one of the most important events during embryogenesis and is vital for postnasal tissue repair. In this paper, we will discuss how ROS regulate different steps in vascular development, including smooth muscle cell differentiation, angiogenesis, endothelial progenitor cells recruitment, and vascular cell migration.

• Publication year

  2013

• Venue

  Oxidative Medicine and Cellular Longevity

• Publication date

  2013-01-22

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1155/2013/374963PMID 23401740PMCID 3564431
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Supplementary Figure S1

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  2012cited by this paper
• Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease.

  2012cited by this paper
• VEGF-induced vascular permeability is mediated by FAK.

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• Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

  2012cited by this paper
• Hypoxia-inducible factors in physiology and medicine.

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• Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension.

  2012influential reference
• Hypoxia Triggers Meiotic Fate Acquisition in Maize

  2012cited by this paper
• VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

  2012cited by this paper
• IQGAP1 and its binding proteins control diverse biological functions.

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• Heme modulates smooth muscle cell proliferation and migration via NADPH oxidase: a counter-regulatory role for heme oxygenase system.

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• Molecular mechanisms and clinical applications of angiogenesis

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• Metabolic regulation of hematopoietic stem cells in the hypoxic niche.

  2011cited by this paper
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• NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor.

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• Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species.

  2011influential reference
• Autophagy: Renovation of Cells and Tissues

  2011cited by this paper
• Mitochondrial complex III ROS regulate adipocyte differentiation.

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• Basic and therapeutic aspects of angiogenesis.

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• Activation of NADPH Oxidase 1 Increases Intracellular Calcium and Migration of Smooth Muscle Cells

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• Slingshot Isoform-Specific Regulation of Cofilin-Mediated Vascular Smooth Muscle Cell Migration and Neointima Formation

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• Transcriptional regulation of ROS controls transition from proliferation to differentiation in the root.

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• Crucial Role of Nrf3 in Smooth Muscle Cell Differentiation From Stem Cells

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• Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling.

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• Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species

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• Platelet-derived growth factor BB stimulates vasculogenesis of embryonic stem cell-derived endothelial cells by calcium-mediated generation of reactive oxygen species.

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• Reactive oxygen species regulate a slingshot-cofilin activation pathway.

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• NADPH oxidases and angiotensin II receptor signaling.

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• NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival

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• Novel p47phox-Related Organizers Regulate Localized NADPH Oxidase 1 (Nox1) Activity

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• Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H2O2.

  2009influential reference
• Reactive Oxygen Species prime Drosophila haematopoietic progenitors for differentiation

  2009cited by this paper
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  2008influential reference
• The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.

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• Endothelial cell migration during angiogenesis.

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• Nox4 Is Required for Maintenance of the Differentiated Vascular Smooth Muscle Cell Phenotype

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• Nox1 Mediates Basic Fibroblast Growth Factor–Induced Migration of Vascular Smooth Muscle Cells

  2007cited by this paper
• FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.

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