TRF1 binds a bipartite telomeric site with extreme spatial flexibility

No abstract is available for this paper.

• Publication year

  1999

• Venue

  EMBO Journal

• Publication date

  1999-10-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/emboj/18.20.5735PMID 10523316PMCID PMC1171640
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mammalian telomeres end in a large duplex loop.

  1999influential reference
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  1998cited by this paper
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  2025influential citation
• The Central Role of Cytogenetics in Radiation Biology

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• Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA

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• Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization

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• TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA

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• Impact of non-synonymous mutations on the structure and function of telomeric repeat binding factor 1

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• Shelterin components modulate nucleic acids condensation and phase separation in the context of telomeric DNA

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• Regulation of Antigenic Variation by Trypanosoma brucei Telomere Proteins Depends on Their Unique DNA Binding Activities

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• TIN2 facilitates TRF1-mediated trans- and cis-interactions on physiologically relevant long telomeric DNA

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• Dynamics of TRF1 organizing a single human telomere

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• Effect of TRF1 rs3863242 polymorphism on telomere length in omethoate-exposed workers

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  2018cites this paper
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  2017cites this paper
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  2015cites this paper
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  2015cites this paper
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• Over-Expression of Telomere Binding Factors (TRF1 & TRF2) in Renal Cell Carcinoma and Their Inhibition by Using SiRNA Induce Apoptosis, Reduce Cell Proliferation and Migration Invitro

  2015cites this paper
• Polymerase alpha components associate with telomeres to mediate overhang processing

  2014cites this paper
• Suppression of subtelomeric VSG switching by Trypanosoma brucei TRF requires its TTAGGG repeat-binding activity

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