Bringing It All Together: Coupling Excision Repair to the DNA Damage Checkpoint

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Photochemistry and Photobiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1111/php.12667PMID 27861980PMCID PMC5315623
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanisms of DNA Repair by Photolyase and Excision Nuclease (Nobel Lecture).

  2016cited by this paper
• DNA damage processing at telomeres: The ends justify the means.

  2016cited by this paper
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• RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling

  2015cited by this paper
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  2015cited by this paper
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  2015cited by this paper
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  2015cited by this paper
• Human telomerase: biogenesis, trafficking, recruitment, and activation

  2015cited by this paper
• Nucleotide excision repair in humans.

  2015cited by this paper
• DNA Repair Synthesis and Ligation Affect the Processing of Excised Oligonucleotides Generated by Human Nucleotide Excision Repair*

  2014cited by this paper
• RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells

  2014cited by this paper
• Polymerase η suppresses telomere defects induced by DNA damaging agents

  2014cited by this paper
• Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System*

  2014cited by this paper
• Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability.

  2014cited by this paper
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  2014cited by this paper
• Telomere length and telomerase activity impact the UV sensitivity syndrome xeroderma pigmentosum C.

  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
• Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence

  2013cited by this paper
• DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation

  2013cited by this paper
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  2013cited by this paper
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  2012cited by this paper
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  2012cited by this paper
• In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling*

  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2011cited by this paper
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• Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)*

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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
• Human Telomeres Are Hypersensitive to UV-Induced DNA Damage and Refractory to Repair

  2010cited by this paper
• TIN2-Tethered TPP1 Recruits Human Telomerase to Telomeres In Vivo

  2010cited by this paper
• Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress*

  2010cited by this paper
• Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.

  2010cited by this paper
• Telomere length and risk of incident cancer and cancer mortality.

  2010cited by this paper
• The Werner syndrome protein functions in repair of Cr(VI)-induced replication-associated DNA damage.

  2009cited by this paper
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  2009cited by this paper
• Telomere attrition and genomic instability in xeroderma pigmentosum type-b deficient fibroblasts under oxidative stress

  2009cited by this paper
• Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells.

  2009cited by this paper
• Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

  2009cited by this paper
• Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.

  2009cited by this paper
• Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA

  2009cited by this paper
• Long Patch Base Excision Repair Proceeds via Coordinated Stimulation of the Multienzyme DNA Repair Complex*

  2009cited by this paper
• Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase*

  2009cited by this paper
• The human ATR-mediated DNA damage checkpoint in a reconstituted system.

  2009cited by this paper
• Cancer in dyskeratosis congenita.

  2009cited by this paper
• How shelterin protects mammalian telomeres.

  2008cited by this paper
• ATR: an essential regulator of genome integrity

  2008cited by this paper
• A Shared Docking Motif in TRF1 and TRF2 Used for Differential Recruitment of Telomeric Proteins

  2008cited by this paper
• The 8,5'-cyclopurine-2'-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair.

  2008cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
• Purification and characterization of Escherichia coli and human nucleotide excision repair enzyme systems.

  2006cited by this paper
• TopBP1 activates the ATR-ATRIP complex.

  2006influential reference
• XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer

  2005cited by this paper
• Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2

  2005cited by this paper
• The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1.

  2004cited by this paper
• Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA.

  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
• The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD.

  2004cited by this paper
• Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.

  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
• Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

  2003influential reference
• Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

  2003cited by this paper
• A splicing mutation affecting expression of ataxia–telangiectasia and Rad3–related protein (ATR) results in Seckel syndrome

  2003cited by this paper
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  2003cited by this paper
• Preferential binding of ATR protein to UV-damaged DNA

  2002cited by this paper
• Structures of the Human Rad17-Replication Factor C and Checkpoint Rad 9-1-1 Complexes Visualized by Glycerol Spray/Low Voltage Microscopy*

  2002cited by this paper
• Oxidative stress shortens telomeres.

  2002cited by this paper
• NOBEL LECTURE: Yeast and Cancer

  2002cited by this paper
• The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

  2001cited by this paper
• Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans

  2001cited by this paper
• Initial sequencing and analysis of the human genome

  2001cited by this paper
• Site-specific DNA damage at the GGG sequence by UVA involves acceleration of telomere shortening.

  2001cited by this paper
• Purification and characterization of human DNA damage checkpoint Rad complexes

  2001cited by this paper
• Individual determination of the yield of the main UV-induced dimeric pyrimidine photoproducts in DNA suggests a high mutagenicity of CC photolesions.

  2001cited by this paper
• Identification of human Rap1: implications for telomere evolution.

  2000cited by this paper

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• The XPA Protein—Life under Precise Control

  2022cites this paper
• Activation of DNA damage response signaling in mammalian cells by ionizing radiation

  2021cites this paper
• Circadian Rhythm of NER and ATR Pathways

  2021cites this paper
• Mechanisms of DNA repair in Trypanosoma cruzi: What do we know so far?

  2020cites this paper
• Comprehensive assessment of the association between XPC rs2228000 and cancer susceptibility based on 26835 cancer cases and 37069 controls

  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper