INVOLVEMENT OF SOMATOSTATIN RECEPTOR SUBTYPES IN MEMBRANE ION CHANNEL MODIFICATION BY SOMATOSTATIN IN PITUITARY SOMATOTROPES

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Clinical and Experimental Pharmacology and Physiology

• Publication date

  2007-12-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1111/j.1440-1681.2007.04806.xPMID 17892506
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Somatostatin decreases voltage-gated Ca2+ currents in GH3 cells through activation of somatostatin receptor 2.

  2007cited by this paper
• Somatostatin increases voltage-gated K+ currents in GH3 cells through activation of multiple somatostatin receptors.

  2005cited by this paper
• Somatostatin receptor subtype 1 selective activation in human growth hormone (GH)- and prolactin (PRL)-secreting pituitary adenomas: effects on cell viability, GH, and PRL secretion.

  2003cited by this paper
• Somatostatin receptor subtypes 2 and 4 affect seizure susceptibility and hippocampal excitatory neurotransmission in mice

  2002cited by this paper
• Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis

  2002cited by this paper
• Targeting of cytotoxic somatostatin analog AN-238 to somatostatin receptor subtypes 5 and/or 3 in experimental pancreatic cancers.

  2001cited by this paper
• Somatostatin receptor subtype 1 (sst(1)) regulates intracellular 3',5'-cyclic adenosine monophosphate accumulation in rat embryonic cortical neurons: evidence with L-797,591, an sst(1)-subtype-selective nonpeptidyl agonist.

  2001cited by this paper
• GiaS and Go, Selectively Associate with the Cloned Somatostatin Receptor Subtype SSTR2*

  2001cited by this paper
• Homo- and Heterodimerization of Somatostatin Receptor Subtypes

  2001cited by this paper
• Protein Tyrosine Nitration in Cytokine-activated Murine Macrophages

  2001cited by this paper
• Expression of somatostatin receptor subtypes and growth inhibition in human exocrine pancreatic cancers.

  2000cited by this paper
• Receptor Isoforms Mediate Opposing Proliferative Effects through Gβγ-Activated p38 or Akt Pathways

  2000cited by this paper
• Diverse intracellular signalling systems used by growth hormone‐releasing hormone in regulating voltage‐gated Ca2+ or K+ channels in pituitary somatotropes

  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
• The pivotal role of phosphoinositide-3 kinase in the human somatostatin sst(4) receptor-mediated stimulation of p44/p42 mitogen-activated protein kinase and extracellular acidification.

  1999cited by this paper
• Nonpeptidyl somatostatin agonists demonstrate that sst2 and sst5 inhibit stimulated growth hormone secretion from rat anterior pituitary cells.

  1999cited by this paper
• Gene Therapy for Pancreatic Carcinoma: Local and Distant Antitumor Effects after Somatostatin Receptor sst2 Gene Transfer

  1999cited by this paper
• Characterisation of human recombinant somatostatin receptors. 3. Modulation of adenylate cyclase activity

  1999cited by this paper
• Characterisation of human recombinant somatostatin receptors. 2. Modulation of GTPγS binding

  1999cited by this paper
• Gi-3 protein mediates the increase in voltage-gated K+ currents by somatostatin on cultured ovine somatotrophs.

  1998cited by this paper
• Gi-3 protein mediates the increase in voltage-gated K+ currents by somatostatin on cultured ovine somatotrophs.

  1998cited by this paper
• Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry.

  1998cited by this paper
• Role of laminin-1, collagen IV, and an autocrine factor(s) in regulated secretion by lacrimal acinar cells.

  1998cited by this paper
• Differential Management of Ca2+ Oscillations by Anterior Pituitary Cells: A Comparative Overview

  1998cited by this paper
• Endogenous pacemaker activity of rat tumour somatotrophs

  1998cited by this paper
• Both Overlapping and Distinct Signaling Pathways for Somatostatin Receptor Subtypes SSTR1 and SSTR2 in Pituitary Cells*

  1997cited by this paper
• Coupling of rat somatostatin receptor subtypes to a G‐protein gated inwardly rectifying potassium channel (GIRK1)

  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• Somatostatin receptor subtype SSTR2 mediates the inhibition of high-voltage-activated calcium channels by somatostatin and its analogue SMS 201-995

  1996cited by this paper
• Somatostatin-14 and its analog octreotide exert a cytostatic effect on GH3 rat pituitary tumor cell proliferation via a transient G0/G1 cell cycle block.

  1995cited by this paper
• The somatostatin receptor family.

  1995cited by this paper
• Effects of Growth Hormone‐Releasing Peptide‐2 (GHRP‐2) on Membrane Ca2+ Permeability in Cultured Ovine Somatotrophs

  1995cited by this paper
• Molecular biology of somatostatin receptors.

  1995cited by this paper
• Modulation of Ca2+ influx in the ovine somatotroph by growth hormone-releasing factor.

  1995cited by this paper
• Transfected human somatostatin receptor type 2, SSTR2, not only inhibits adenylate cyclase but also stimulates phospholipase C and Ca2+ mobilization.

  1994cited by this paper
• Molecular Pharmacology of Somatostatin‐receptor Subtypes

  1994cited by this paper
• Localization of somatostatin (SRIF) SSTR-1, SSTR-2 and SSTR-3 receptor mRNA in rat brain by in situ hybridization

  1994cited by this paper
• Somatostatin receptor subtype SSTR2 mediates the inhibition of high‐voltage‐activated calcium channels by somatostatin and its analogue SMS 201‐995

  1994cited by this paper
• Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade.

  1994cited by this paper
• Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2.

  1994cited by this paper
• Voltage-dependent potassium currents in ovine somatotrophs and their function in growth hormone secretion.

  1994cited by this paper
• Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.

  1994cited by this paper
• Multiple effector coupling of somatostatin receptor subtype SSTR1.

  1994cited by this paper
• Phospholipase C activation and Ca2+ mobilization by cloned human somatostatin receptor subtypes 1–5, in transfected COS‐7 cells

  1994cited by this paper
• Characterization of cloned human somatostatin receptor SSTR5.

  1994cited by this paper
• The effect of GH-releasing peptide-2 (GHRP-2 or KP 102) on GH secretion from primary cultured ovine pituitary cells can be abolished by a specific GH-releasing factor (GRF) receptor antagonist.

  1994cited by this paper
• Ion channels and the signal transduction pathways in the regulation of growth hormone secretion.

  1994cited by this paper
• Differential expression of messenger RNAs for somatostatin receptor subtypes SSTR1, SSTR2 and SSTR3 in adult rat brain: analysis by RNA blotting and in situ hybridization histochemistry.

  1994cited by this paper
• All five cloned human somatostatin receptors (hSSTR1-5) are functionally coupled to adenylyl cyclase.

  1994cited by this paper
• Effects in vitro of New Growth Hormone Releasing Peptide (GHRP‐1) on Growth Hormone Secretion from Ovine Pituitary Cells in Primary Culture

  1994cited by this paper
• Somatostatin messenger RNA-containing neurons in Alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex.

  1994cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
• Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase.

  1992cited by this paper
• Characterization of a membrane tyrosine phosphatase in AR42J cells: regulation by somatostatin.

  1992cited by this paper
• Cloning and expression of a rat somatostatin receptor enriched in brain.

  1992cited by this paper
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  1992cited by this paper
• Molecular cloning and expression of a pituitary somatostatin receptor with preferential affinity for somatostatin-28.

  1992cited by this paper
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  1992cited by this paper
• Expression cloning of a rat brain somatostatin receptor cDNA.

  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1990cited by this paper
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  1990cited by this paper
• Two types of voltage‐dependent calcium current in rat somatotrophs are reduced by somatostatin.

  1990cited by this paper
• Somatostatin increases voltage-dependent potassium currents in rat somatotrophs.

  1990cited by this paper
• Electrophysiological responses of rat pituitary cells in somatotroph-enriched primary culture to human growth-hormone releasing factor.

  1989cited by this paper
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  1989cited by this paper
• Whole‐cell recordings of ionic currents in bovine somatotrophs and their involvement in growth hormone secretion.

  1988cited by this paper
• Reconstitution of somatostatin and muscarinic receptor mediated stimulation of K+ channels by isolated GK protein in clonal rat anterior pituitary cell membranes.

  1987cited by this paper
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  1987cited by this paper
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  1983cited by this paper
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  1983cited by this paper
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  1978cited by this paper
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  1978cited by this paper
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  1977cited by this paper
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  1977cited by this paper
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  1975cited by this paper

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