Functional T cell reconstitution and human immunodeficiency virus-1-specific cell-mediated immunity during highly active antiretroviral therapy.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Infectious Diseases

• Publication date

  1999-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1086/314837PMID 10353864
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A CONTROLLED TRIAL OF TWO NUCLEOSIDE ANALOGUES PLUS INDINAVIR IN PERSONS WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION AND CD4 CELL COUNTS OF 200 PER CUBIC MILLIMETER OR LESS

  2000cited by this paper
• Antigen-specific T-lymphocyte proliferative responses during highly active antiretroviral therapy (HAART) of HIV-1 infection.

  1999cited by this paper
• Decay Kinetics of Human Immunodeficiency Virus-Specific Effector Cytotoxic T Lymphocytes after Combination Antiretroviral Therapy

  1999cited by this paper
• Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1

  1998cited by this paper
• Recovery of the immune system with antiretroviral therapy: the end of opportunism?

  1998cited by this paper
• Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA.

  1998cited by this paper
• Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation

  1998cited by this paper
• A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

  1998cited by this paper
• An open randomized controlled trial of zidovudine plus lamivudine versus stavudine plus lamivudine

  1998cited by this paper
• Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease.

  1998cited by this paper
• Evolution of cytotoxic T lymphocyte responses to human immunodeficiency virus type 1 in patients with symptomatic primary infection receiving antiretroviral triple therapy.

  1998cited by this paper
• Diversity of the T‐cell receptor BV repertoire in HIV‐1‐infected patients reflects the biphasic CD4+ T‐cell repopulation kinetics during highly active antiretroviral therapy

  1998cited by this paper
• Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: a predominant gag-specific response is associated with nonprogressive infection.

  1998cited by this paper
• Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy

  1998cited by this paper
• Limited CD4+ T-cell renewal in early HIV-1 infection: Effect of highly active antiretroviral therapy

  1998cited by this paper
• Decrease of HIV‐1 RNA levels in lymphoid tissue and peripheral blood during treatment with ritonavir, lamivudine and zidovudine

  1998cited by this paper
• Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical Trials Group Protocol 315.

  1998cited by this paper
• Lack of T-cell proliferative response to HIV-1 antigens after 1 year of highly active antiretroviral treatment in early HIV-1 disease

  1998cited by this paper
• Lack of T-cell proliferative response to HIV-1 antigens after 1 year of highly active antiretroviral treatment in early HIV-1 disease. Immunology Study Group of Spanish EARTH-1 Study.

  1998cited by this paper
• How immune-based interventions can change HIV therapy

  1997cited by this paper
• A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team.

  1997cited by this paper
• Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy.

  1997cited by this paper
• Gag-Specific Immune Responses after Immunization with pl7/p24:Ty Virus-Like Particles in HIV Type 1-Seropositive Individuals

  1997cited by this paper
• Recovery of replication-competent HIV despite prolonged suppression of plasma viremia.

  1997cited by this paper
• Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia.

  1997cited by this paper
• Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection.

  1997cited by this paper
• Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease.

  1997cited by this paper
• Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy.

  1997cited by this paper
• Alterations in the immune response of human immunodeficiency virus (HIV)-infected subjects treated with an HIV-specific protease inhibitor, ritonavir.

  1996cited by this paper
• Different patterns of HIV‐1‐specific cytotoxic T‐lymphocyte activity after primary infection

  1995cited by this paper
• Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

  1995cited by this paper
• Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics

  1995cited by this paper
• Viral dynamics in human immunodeficiency virus type 1 infection

  1995cited by this paper
• 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults.

  1993cited by this paper
• Selective in vitro expansion of HLA class I‐restricted HIV‐1 Gag‐specific CD8 + T cells: cytotoxic T‐lymphocyte epitopes and precursor frequencies

  1993cited by this paper
• Zidovudine‐induced restoration of cell‐mediated immunity to mycobacteria in immunodeficient HIV‐infected patients

  1992cited by this paper
• HIV-1 Core Proteins Expressed from Recombinant Vaccinia Viruses

  1989cited by this paper
• Whole-blood lymphocyte cultures.

  1989cited by this paper
• Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging.

  1989cited by this paper
• Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.

  1988cited by this paper
• Limiting dilution assays. Experimental design and statistical analysis.

  1987cited by this paper
• Risk factors and prevalence of HIV antibodies in homosexual men in the Netherlands.

  1987cited by this paper

• Mathematical models for HIV treatment : A schematic review

  2020cites this paper
• Vertically Acquired HIV Infection in Children Modulates Hepatitis B Surface Antigen Specific IgG Subclass Distribution After Early Childhood Vaccination Against Hepatitis B Virus Infection

  2018cites this paper
• Immunity to HIV

  2016cites this paper
• Poor functional immune recovery in aged HIV-1-infected patients following successfully treatment with antiretroviral therapy.

  2015cites this paper
• Engineering T Cells to Functionally Cure HIV-1 Infection.

  2015cites this paper
• Effect of Highly Active Antiretroviral Therapy on T-Cell Sub-population Profile in Human Immunodeficiency Virus-1 Infected Patients

  2015cites this paper
• HIV Inside the Body: A Review of Mathematical Modeling

  2014cites this paper
• Influence of Episodes of Intermittent Viremia (“Blips”) on Immune Responses and Viral Load Rebound in Successfully Treated HIV-Infected Patients

  2013cites this paper
• Vaccination against hepatitis B with 4-double doses increases response rates and antibodies titers in HIV-infected adults.

  2012cites this paper
• Combination Therapy of AIDS

  2012cites this paper
• Immunisation thérapeutique chez des patients infectés par le vih recevant un traitement antirétroviral stable

  2011cites this paper
• Therapeutic immunization in HIV infected Ugandans receiving stable antiretroviral treatment: a Phase I safety study.

  2011cites this paper
• Drug treatment of HIV and AIDS

  2010cites this paper
• Recombinant HBsAg Vaccine in Persons with HIV: Is Seroconversion Sufficient for Long-term Protection?

  2010cites this paper
• Impact of γ‐chain cytokines on T cell homeostasis in HIV‐1 infection: therapeutic implications

  2010cites this paper
• Oral manifestations in human immunodeficiency virus infected children in highly active antiretroviral therapy era.

  2009cites this paper
• Human immunodeficiency virus and human papilloma virus - why HPV-induced lesions do not spontaneously resolve and why therapeutic vaccination can be successful

  2009cites this paper
• Restoration of anti‐tetanus toxoid responses in patients initiating highly active antiretroviral therapy with or without a boost immunization: an INITIO substudy

  2008cites this paper
• Pathogenesis of liver damage in HCV-HIV patients.

  2008cites this paper
• Immunotherapy of HIV Infection: Dendritic Cells as Targets and Tools

  2007cites this paper
• Antibody response to hepatitis B re-vaccination in HIV-infected children with immune recovery on highly active antiretroviral therapy.

  2007cites this paper
• Divergence in CD8+ T cell epitopes of HIV -1 as an immune escape mechanism

  2007cites this paper
• Three-Year Immune Reconstitution in PI-Sparing and PI-Containing Antiretroviral Regimens in Advanced HIV-1 Disease

  2007cites this paper
• CD8+ Cell Noncytotoxic Anti-HIV Response: Restoration by HAART in the Late Stage of Infection

  2006cites this paper
• Long-Term Highly Active Antiretroviral Therapy in Chronic HIV-1 Infection: Evidence for Reconstitution of Antiviral Immunity

  2006cites this paper
• Human Immunodeficiency Virus-Infected Patients with Prior Pneumocystis Pneumonia Exhibit Increased Serologic Reactivity to Several Major Surface Glycoprotein Clones

  2006cites this paper
• Immune Restoration Under HAART in Patients Chronically Infected with HIV-1: Diversity of T, B, and NK Immune Responses

  2006cites this paper
• Outcomes for therapeutic vaccines trials

  2006cites this paper
• Large HIV‐specific CD8+ cytotoxic T‐lymphocyte (CTL) clones reduce their overall size but maintain high frequencies of memory CTL following highly active antiretroviral therapy

  2006cites this paper
• Syndromes de reconstitution immunitaire chez les patients infectés par le VIH

  2006cites this paper
• HIV-1-Specific CD4+ T Cell Responses in Chronically HIV-1 Infected Blippers on Antiretroviral Therapy in Relation to Viral Replication Following Treatment Interruption

  2006cites this paper
• Persistant immunodominant anti-gag SLYNTVATL responses in HIV-patients with up to 7 years of HAART.

  2006cites this paper
• SIV‐specific T lymphocyte responses in PBMC and lymphoid tissues of SIV‐infected pigtailed macaques during suppressive combination antiretroviral therapy

  2005cites this paper
• British HIV Association guidelines for the treatment of HIV‐1‐infected adults with antiretroviral therapy 2008

  2005cites this paper
• Hormonal contraceptive use and the effectiveness of highly active antiretroviral therapy.

  2005cites this paper
• Differences in Presentation and Outcome of Invasive Pneumococcal Disease among Patients with and without HIV Infection in the Pre-HAART Era

  2005cites this paper
• Flow Cytometry Evaluation of the T-Cell ReceptorVβ Repertoire Among HIV-1 Infected Individuals Before and After Antiretroviral Therapy

  2005cites this paper
• Viro-immunology of EBV-HIV co-infection

  2005cites this paper
• Syndromes de reconstitution immunologique au cours des mycoses systémiques chez les patients infectés par le VIH

  2005cites this paper
• Infections and SLE

  2005cites this paper
• Persistent low viral load on antiretroviral therapy is associated with T cell-mediated control of HIV replication

  2005cites this paper
• Undetectable plasma HIV RNA load predicts success after hepatitis B vaccination in HIV-infected persons.

  2005cites this paper
• 14 - HIV and Autoimmunity

  2005cites this paper
• In HIV Type 1-Infected Children Cytotoxic T Lymphocyte Responses Are Associated with Greater Reduction of Viremia under Antiretroviral Therapy

  2005cites this paper
• Evaluating therapeutic vaccines in patients infected with HIV

  2004cites this paper
• Tetanus vaccination with IL-2 during highly active antiretroviral therapy induces sustained and pronounced specific CD4 T-cell responses

  2004cites this paper
• Limited long‐term naive CD4+ T cell reconstitution in patients experiencing viral load rebounds during HAART

  2004cites this paper
• The use of growth factors and cytokines to treat opportunistic infections in HIV-1 disease.

  2004cites this paper
• Immune reconstitution in HIV infection

  2004cites this paper
• Association of T cell proliferative responses and phenotype with virus control in chronic progressive HIV-1 disease.

  2004cites this paper
• Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1.

  2004cites this paper
• 38 - SLE and Infections

  2004cites this paper
• Increase in plasmacytoid and myeloid dendritic cells by progenipoietin-1, a chimeric Flt-3 and G-CSF receptor agonist, in SIV-Infected rhesus macaques.

  2004cites this paper
• A New Aspect for the Pathogenesis of AIDS Establishment

  2004cites this paper
• Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or function

  2004cites this paper
• Presence of HIV-Specific CD4+ T-Cell Responses in HIV-Infected Subjects With Sustained Virologic Control After Highly Active Antiretroviral Therapy

  2004cites this paper
• Long-term persistence of vaccination and HAART to human immunodeficiency virus (HIV).

  2004cites this paper
• Immune restoration disease in HIV-infected individuals receiving highly active antiretroviral therapy: clinical and immunological characteristics.

  2003cites this paper
• SLE and infections

  2003cites this paper
• Viral load and CD4+ T lymphocyte response to highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children: an observational study.

  2003cites this paper
• Immune reconstitution is comparable in antiretroviral-naive subjects after 1 year of successful therapy with a nucleoside reverse-transcriptase inhibitor- or protease inhibitor-containing antiretroviral regimen.

  2003cites this paper
• Reconstitution of CD4+ T cell responses in HIV‐1 infected individuals initiating highly active antiretroviral therapy (HAART) is associated with renewed interleukin‐2 production and responsiveness

  2003cites this paper
• Changes of lymphocyte apoptosis associated with sequential introduction of highly active antiretroviral therapy

  2003cites this paper
• Therapeutic HIV vaccines.

  2003cites this paper
• Immunity to Human Immunodeficiency Virus (HIV) in Children with Chronic HIV Infection Receiving Highly Active Antiretroviral Therapy

  2003cites this paper
• Dual Nucleoside Therapy for HIV Infection: Analysis of Results and Factors Influencing Viral Response and Long Term Efficacy

  2003cites this paper
• Long-term effects of protease-inhibitor-based combination therapy on CD4 T-cell recovery in HIV-1-infected children and adolescents.

  2003cites this paper
• The effect of HAART on humoral immune response in primary HIV-1 infected patients.

  2002cites this paper
• Interleukin-2 accelerates CD4 cell reconstitution in HIV-infected patients with severe immunosuppression despite highly active antiretroviral therapy: the ILSTIM study – ANRS 082

  2002cites this paper
• Characterization of Human Immunodeficiency Virus Type 1 (HIV-1) Gag- and Gag Peptide-Specific CD4+ T-Cell Clones from an HIV-1-Seronegative Donor following In Vitro Immunization

  2002cites this paper
• Modulation of Human Immunodeficiency Virus (HIV)-Specific Immune Response by Using Efavirenz, Nelfinavir, and Stavudine in a Rescue Therapy Regimen for HIV-Infected, Drug-Experienced Patients

  2002cites this paper
• Human papillomavirus-associated oral warts among human immunodeficiency virus-seropositive patients in the era of highly active antiretroviral therapy: an emerging infection.

  2002cites this paper
• Human Immunodeficiency Virus Type 1-Hepatitis C Virus Coinfection: Intraindividual Comparison of Cellular Immune Responses against Two Persistent Viruses

  2002cites this paper
• T-cell subset counting and the fight against AIDS: reflections over a 20-year struggle.

  2002cites this paper
• Immune Reconstitution with Antiretroviral Chemotherapy

  2002cites this paper
• Plasticity of lymphoid compartments during HIV infection and treatments: hopes and limits.

  2002cites this paper
• Pilot study of the effects of intermittent interleukin-2 on human immunodeficiency virus (HIV)-specific immune responses in patients treated during recently acquired HIV infection.

  2002cites this paper
• Induction of Anti-Human Immunodeficiency Virus Type 1 (HIV-1) CD8+ and CD4+ T-Cell Reactivity by Dendritic Cells Loaded with HIV-1 X4-Infected Apoptotic Cells

  2002cites this paper
• Combined Autoimmune Disease in a Patient with AIDS

  2002cites this paper
• Goals and milestones during treatment of HIV-1 infection with antiretroviral therapy: a pathogenesis-based perspective.

  2002cites this paper
• HIV and autoimmunity.

  2002cites this paper
• Early and late effects of highly active antiretroviral therapy: a 2 year follow-up of antiviral-treated and antiviral-naive chronically HIV-infected patients

  2002cites this paper
• Impact of suppression of viral replication by highly active antiretroviral therapy on immune function and phenotype in chronic HIV-1 infection.

  2002cites this paper
• Serologic responses to epitopes of the major surface glycoprotein of Pneumocystis jiroveci differ in human immunodeficiency virus-infected and uninfected persons.

  2002cites this paper
• Immunotherapy for Infectious Diseases

  2002influential citation
• Residual Viral Replication during Antiretroviral Therapy Boosts Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses in Subjects Treated Early after Infection

  2002cites this paper
• CD8+ T-cell immunity to HIV infection.

  2002cites this paper
• Evidence of HIV-1 Adaptation to HLA-Restricted Immune Responses at a Population Level

  2002cites this paper
• Dendritic cell therapies for HIV-1 infection

  2001cites this paper
• Emerging concepts in gastrointestinal aspects of HIV-1 pathogenesis and management

  2001cites this paper
• Immunological Effects of Interleukin-2 Therapy in Human Immunodeficiency Virus-Positive Subjects

  2001cites this paper
• Human immunodeficiency virus pathogenesis: insights from studies of lymphoid cells and tissues.

  2001cites this paper
• HIV dynamics and T-cell immunity after three structured treatment interruptions in chronic HIV-1 infection

  2001cites this paper
• Potent Antiretroviral Therapy Initiates Normalization of Hypergammaglobulinemia and a Decline in HIV Type 1-Specific Antibody Responses

  2001cites this paper
• T cell responses to highly active antiretroviral therapy defined by chemokine receptors expression, cytokine production, T cell receptor repertoire and anti‐HIV T‐lymphocyte activity

  2001cites this paper
• Interleukin-7 restores immunity in athymic T-cell-depleted hosts.

  2001cites this paper
• T cell expansions in lymph nodes and peripheral blood in HIV-1-infected individuals: effect of antiretroviral therapy

  2001cites this paper
• Transient Mobilization of Human Immunodeficiency Virus (HIV)-Specific CD4 T-Helper Cells Fails To Control Virus Rebounds during Intermittent Antiretroviral Therapy in Chronic HIV Type 1 Infection

  2001cites this paper
• Highly Active Antiretroviral Therapy in Human Immunodeficiency Virus Type 1-Infected Children: Analysis of Cellular Immune Responses

  2001cites this paper
• CD4 T cell recovery is slower in patients experiencing viral load rebounds during HAART

  2001cites this paper