Gdnf is mitogenic, neurotrophic, and chemoattractive to enteric neural crest cells in the embryonic colon

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Developmental Dynamics

• Publication date

  2011-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/dvdy.22630PMID 21465624PMCID PMC3092856
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A series of normal stages in the development of the chick embryo. 1951.

  2012cited by this paper
• Neural crest regionalisation for enteric nervous system formation: implications for Hirschsprung's disease and stem cell therapy.

  2010cited by this paper
• Effects of tissue age, presence of neurones and endothelin‐3 on the ability of enteric neurone precursors to colonize recipient gut: implications for cell‐based therapies

  2010cited by this paper
• Age-dependent changes in the gut environment restrict the invasion of the hindgut by enteric neural progenitors

  2009cited by this paper
• Prokineticin-1 (Prok-1) works coordinately with glial cell line-derived neurotrophic factor (GDNF) to mediate proliferation and differentiation of enteric neural crest cells.

  2008influential reference
• Critical numbers of neural crest cells are required in the pathways from the neural tube to the foregut to ensure complete enteric nervous system formation

  2008cited by this paper
• Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice.

  2008influential reference
• Cell proliferation drives neural crest cell invasion of the intestine.

  2007cited by this paper
• Conditional ablation of GFRα1 in postmigratory enteric neurons triggers unconventional neuronal death in the colon and causes a Hirschsprung's disease phenotype

  2007cited by this paper
• Effect of Gdnf haploinsufficiency on rate of migration and number of enteric neural crest‐derived cells

  2007influential reference
• Behavior of enteric neural crest‐derived cells varies with respect to the migratory wavefront

  2007cited by this paper
• Mathematical and experimental insights into the development of the enteric nervous system and Hirschsprung's Disease

  2007cited by this paper
• Endothelin-3 regulates neural crest cell proliferation and differentiation in the hindgut enteric nervous system.

  2006influential reference
• A robust system for RNA interference in the chicken using a modified microRNA operon.

  2006cited by this paper
• A common sex-dependent mutation in a RET enhancer underlies Hirschsprung disease risk

  2005cited by this paper
• Dynamics of neural crest-derived cell migration in the embryonic mouse gut.

  2004cited by this paper
• Enteric nervous system progenitors are coordinately controlled by the G protein-coupled receptor EDNRB and the receptor tyrosine kinase RET.

  2003influential reference
• GDNF availability determines enteric neuron number by controlling precursor proliferation

  2003cited by this paper
• Gdnf haploinsufficiency causes Hirschsprung-like intestinal obstruction and early-onset lethality in mice.

  2002cited by this paper
• Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis.

  2002cited by this paper
• GDNF is a chemoattractant for enteric neural cells.

  2001influential reference
• Hirschsprung disease, associated syndromes and genetics: a review

  2001influential reference
• Functional analysis of zebrafish GDNF.

  2001cited by this paper
• Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis.

  2001cited by this paper
• Hirschsprung disease, associated syndromes, and genetics: a review

  2001cited by this paper
• Developmental regulation of GDNF response and receptor expression in the enteric nervous system.

  2000influential reference
• Inhibition of in vitro enteric neuronal development by endothelin-3: mediation by endothelin B receptors.

  1999cited by this paper
• Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system.

  1999influential reference
• Analysis of protein and gene expression.

  1999cited by this paper
• The sacral neural crest contributes neurons and glia to the post-umbilical gut: spatiotemporal analysis of the development of the enteric nervous system.

  1998cited by this paper
• Age-Dependent Differences in the Effects of GDNF and NT-3 on the Development of Neurons and Glia from Neural Crest-Derived Precursors Immunoselected from the Fetal Rat Gut: Expression of GFRα-1in Vitroandin Vivo

  1998influential reference
• Neurturin and GDNF promote proliferation and survival of enteric neuron and glial progenitors in vitro.

  1998influential reference
• Age-dependent differences in the effects of GDNF and NT-3 on the development of neurons and glia from neural crest-derived precursors immunoselected from the fetal rat gut: expression of GFRalpha-1 in vitro and in vivo.

  1998influential reference
• GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys.

  1998cited by this paper
• GDNF and ET-3 differentially modulate the numbers of avian enteric neural crest cells and enteric neurons in vitro.

  1998influential reference
• Migration of enteric neural crest cells in relation to growth of the gut in avian embryos.

  1996cited by this paper
• Defects in enteric innervation and kidney development in mice lacking GDNF

  1996influential reference
• Renal and neuronal abnormalities in mice lacking GDNF

  1996influential reference
• Renal agenesis and the absence of enteric neurons in mice lacking GDNF

  1996influential reference
• Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

  1994cited by this paper
• Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors.

  1991cited by this paper
• Fate mapping study of the splanchnopleural mesoderm of the 1.5-day-old chick embryo

  1991cited by this paper
• The migration of neural crest cells to the wall of the digestive tract in avian embryo.

  1973cited by this paper
• A series of normal stages in the development of the chick embryo

  1951cited by this paper

• Success of GDNF-based treatment of Hirschsprung disease depends on NCAM1 signaling and various subtypes of enteric neural progenitors

  2025cites this paper
• Retinoic Acid Inhibition Alters Intestinal Composition in Zebrafish: A Non‐genetic Model to Study Hirschsprung Disease?

  2025cites this paper
• Neural Crest Migration Orchestrated by Molecular and Mechanical Signals.

  2025cites this paper
• Endothelin-3 and T-type Ca2+ channels drive enteric neural crest cell calcium activity, contractility and migration

  2025cites this paper
• Electroacupuncture improves gastrointestinal motility through a central-cholinergic pathway-mediated GDNF releasing from intestinal glial cells to protect intestinal neurons in Parkinson's disease rats

  2024cites this paper
• Causes and consequences: development and pathophysiology of Hirschsprung disease

  2024cites this paper
• Interindividual Variation in Gut Nitrergic Neuron Density Is Regulated By GDNF Levels and ETV1

  2024cites this paper
• Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos.

  2024cites this paper
• A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development.

  2023cites this paper
• Isolation, Expansion, and Endoscopic Delivery of Autologous Enteric Neuronal Stem Cells in Swine

  2023cites this paper
• Essential Role of BMP4 Signaling in the Avian Ceca in Colorectal Enteric Nervous System Development

  2023cites this paper
• Origin of enteric nervous system cells and migration pathways during embryonic development

  2022cites this paper
• Short-Chain Fatty Acids as Bacterial Enterocytes and Therapeutic Target in Diabetes Mellitus Type 2

  2022influential citation
• Signaling pathways in the control of embryonic development of the enteric nervous system

  2022cites this paper
• Disorders of the enteric nervous system — a holistic view

  2021cites this paper
• Avian ceca are required for hindgut enteric nervous system development by inhibiting neuronal differentiation via non-canonical Wnt signaling and by promoting enteric neural crest cell proliferation.

  2021cites this paper
• Opportunities for novel diagnostic and cell-based therapies for Hirschsprung disease.

  2021cites this paper
• Treatment and Prevention of Neurocristopathies.

  2021cites this paper
• The role of GDNF and its receptor GFRa1 in neuronal development and function

  2020influential citation
• Development of the Autonomic Nervous System: Clinical Implications

  2020cites this paper
• MMP-9 processing of intestinal smooth muscle-derived GDNF is required for neurotrophic action on enteric neurons.

  2020cites this paper
• Large intestine embryogenesis: Molecular pathways and related disorders (Review)

  2020cites this paper
• Epigenetic factors Dnmt1 and Uhrf1 coordinate intestinal development.

  2019cites this paper
• The road best traveled: Neural crest migration upon the extracellular matrix.

  2019cites this paper
• [Effect of enhancer of zeste homolog 2 on the expression of glial cell line-derived neurotrophic factor family receptor α-1 in the colon tissue of children with Hirschsprung's disease].

  2019influential citation
• Development of the Enteric Nervous System

  2019cites this paper
• Interrogating the development of Enteric Nervous System in zebrafish using transcriptomics

  2019cites this paper
• The biomechanics of collective neural crest cell chemotaxis

  2018cites this paper
• Neural crest cells and the mesentery

  2018influential citation
• Epigenetic factors coordinate intestinal development

  2018influential citation
• Enteric nervous system development: A crest cell's journey from neural tube to colon.

  2017cites this paper
• Potential association of VAMP5 polymorphisms with total colonic aganglionosis in Hirschsprung disease

  2016cites this paper
• Sonic hedgehog controls enteric nervous system development by patterning the extracellular matrix

  2016cites this paper
• Enteric nervous system development in avian and zebrafish models.

  2016cites this paper
• Chemotaxis during neural crest migration.

  2016cites this paper
• Sonic hedgehog is a chemotactic neural crest cell guide that is perturbed by ethanol exposure.

  2016cites this paper
• Enteric nervous system development in avian and zebra fi sh models

  2016cites this paper
• A collagen VI-dependent pathogenic mechanism for Hirschsprung's disease.

  2015cites this paper
• FOR DOCTORAL DEGREE ( Ph . D . )

  2015cites this paper
• Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation of Silencer Elements in a Large Gene Desert of Chromosome 10

  2015cites this paper
• Why are enteric ganglia so small? Role of differential adhesion of enteric neurons and enteric neural crest cells.

  2015cites this paper
• Comparison of GDF5 and GDNF as neuroprotective factors for postnatal dopamine neurons in ventral mesencephalic cultures

  2014cites this paper
• GDNF and GFRα co-receptor family in the developing feline gut.

  2014cites this paper
• PleiotRHOpic

  2014cites this paper
• Generation of avian sarcoma-leukosis viruses to achieve lymphatic-specific expression of a fluorescent marker in an ex-ovo CAM model

  2014cites this paper
• Approaches for Neural Tissue Regeneration

  2013cites this paper
• Building a brain in the gut: development of the enteric nervous system

  2013cites this paper
• RET receptor in the gut of developing cat.

  2013cites this paper
• The clinical significance of pathological studies of congenital intestinal atresia.

  2013cites this paper
• GDNF Signaling Levels Control Migration and Neuronal Differentiation of Enteric Ganglion Precursors

  2013cites this paper
• FGF2 deficit during development leads to specific neuronal cell loss in the enteric nervous system

  2012cites this paper
• Nerve-Cancer Interactions in the Stromal Biology of Pancreatic Cancer

  2012cites this paper
• Artemin and Its Emerging Role in Pathogenesis of Systemic Tumors Besides Pancreatic Cancers

  2012cites this paper
• Balancing neural crest cell intrinsic processes with those of the microenvironment in Tcof1 haploinsufficient mice enables complete enteric nervous system formation.

  2012cites this paper
• Promoting engraftment of transplanted neural stem cells/progenitors using biofunctionalised electrospun scaffolds.

  2012cites this paper
• SIGNALNI PUTEVI U KONTROLI EMBRIONALNOG RAZVOJA ENTERIČKOG NERVNOG SISTEMA

  year unknowninfluential citation