Functional TLRs and NODs in Human Gingival Fibroblasts

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of dentistry research

• Publication date

  2007-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1177/154405910708600310PMID 17314257
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pathogen recognition and innate immunity.

  2006cited by this paper
• Toll-like Receptors, NOD1, and NOD2 in Oral Epithelial Cells

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• Downloaded from jdr.sagepub.com at PENNSYLVANIA STATE UNIV on February 23, 2013 For personal use only. No other uses without permission. International and American Associations for Dental ResearchRESEARCH REPORTS Biological

  2006cited by this paper
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  2004influential reference
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  2003cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  1999cited by this paper
• Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB.

  1999cited by this paper
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  1998cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1991cited by this paper
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  1990cited by this paper

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