One of the ultimate goals in plant systems biology is to elucidate the genotype-phenotype relationship in plant cellular systems. Integrated network analysis that combines omics data with mathematical models has received particular attention. Here we focus on the latest cutting-edge computational advances that facilitate their combination. We highlight (1) network visualization tools, (2) pathway analyses, (3) genome-scale metabolic reconstruction, and (4) the integration of high-throughput experimental data and mathematical models. Multi-omics data that contain the genome, transcriptome, proteome, and metabolome and mathematical models are expected to integrate and expand our knowledge of complex plant metabolisms.
Integrated network analysis and effective tools in plant systems biology
A. Fukushima,S. Kanaya,Kozo Nishida
Published 2014 in Frontiers in Plant Science
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- Publication year
2014
- Venue
Frontiers in Plant Science
- Publication date
2014-11-04
- Fields of study
Biology, Medicine, Computer Science, Environmental Science
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- External record
- Source metadata
Semantic Scholar, PubMed
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