The 677C-->T mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Atherosclerosis

• Publication date

  1997-07-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0021-9150(97)00084-1PMID 9247365
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The (Ala-Val) mutation of methylenetetrahydrofolate reductase as a genetic risk factor for vascular disease in non-insulin-dependent diabetic patients.

  1997cited by this paper
• Homocysteine, B-vitamins and cardiovascular disease : epidemiologic evidence

  1996cited by this paper
• The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia.

  1996cited by this paper
• Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation.

  1996cited by this paper
• Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.

  1996cited by this paper
• Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease.

  1996cited by this paper
• Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.

  1996cited by this paper
• Elevated total plasma homocysteine and 677C-->T mutation of the 5,10-methylenetetrahydrofolate reductase gene in thrombotic vascular disease.

  1996cited by this paper
• Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians.

  1996cited by this paper
• Genetic analysis of thermolabile methylenetetrahydrofolate reductase as a risk factor for myocardial infarction.

  1996cited by this paper
• Methylenetetrahydrofolate reductase mutation and coronary artery disease.

  1996cited by this paper
• Molecular variant of 5,10-methylenetetrahydrofolate reductase is a risk factor of ischemic heart disease in the Japanese population.

  1996cited by this paper
• Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction. A case-control study.

  1996cited by this paper
• Homocysteine and risk of premature coronary heart disease. Evidence for a common gene mutation.

  1996cited by this paper
• Pro-thrombotic effects of a folic acid deficient diet in rat platelets and macrophages related to elevated homocysteine and decreased n-3 polyunsaturated fatty acids.

  1996cited by this paper
• Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia.

  1995cited by this paper
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  1995cited by this paper
• Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis.

  1995cited by this paper
• A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes.

  1995cited by this paper
• A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

  1995cited by this paper
• Homocysteine: relationship to serum cobalamin, serum folate, erythrocyte folate, and lobation of neutrophils.

  1994cited by this paper
• Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease.

  1994cited by this paper
• Vitamin B-6 deficiency vs folate deficiency: comparison of responses to methionine loading in rats.

  1994cited by this paper
• Plasma homocyst(e)ine as a risk factor for early familial coronary artery disease.

  1994cited by this paper
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  1993cited by this paper
• Prevalence of familial hyperhomocyst(e)inemia in men with premature coronary artery disease.

  1991cited by this paper
• Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.

  1991cited by this paper
• The prevalence of homocysteinemia and hypercholesterolemia in angiographically defined coronary heart disease

  1991cited by this paper
• Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease. Effects of pyridoxine and folic acid treatment.

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• Thermolabile methylenetetrahydrofolate reductase in patients with coronary artery disease.

  1988cited by this paper
• Human nutrition and dietetics

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  2019cites this paper
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  2014cites this paper
• Association of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms with myocardial infarction in Tunisian young patients

  2014cites this paper
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  2013cites this paper
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  2013cites this paper
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  2012cites this paper
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  2012cites this paper
• Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

  2011cites this paper
• Hiperhomocisteinemia, polimorfismos genéticos y síndrome coronario agudo

  2011cites this paper
• Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

  2011cites this paper
• Impact of MTHFR C677T gene polymorphism and vitamins intake on homocysteine concentration in the Polish adult population.

  2011cites this paper
• Pathway of Homocysteine? Is the Oral Methionine Loading Test Insensitive to the Remethylation

  2011cites this paper
• ANALIZA POLIMORFIZMÓW GENÓW KODUJ ĄCYCH ENZYMY OBIEGU AKTYWNEGO METYLU W NOWOTWORACH ZËO ŚLIWYCH JAJNIKA I BËONY ŚLUZOWEJ TRZONU MACICY

  2011cites this paper
• Effect of enalapril on plasma homocysteine levels in patients with essential hypertension

  2010cites this paper
• MTHFR and the risk for cerebral venous thrombosis--a meta-analysis.

  2010cites this paper
• Nutrigenetic impact of daily folate intake on plasma homocysteine and folate levels in patients with different methylenetetrahydrofolate reductase genotypes

  2010cites this paper
• Methylenetetrahydrofolate reductase polymorphism: An independent risk determinant of coronary heart disease in an endogamous population from Delhi (India) ☆

  2010cites this paper
• C677T polymorphism of the 5,10 MTHFR gene in young Mexican subjects with ST-elevation myocardial infarction.

  2010cites this paper
• Polymorphism of the methylenetetrahydrofolate reductase gene association with homocysteine and ischemic stroke in type 2 diabetes.

  2009cites this paper
• Association between a single nucleotide polymorphism in MTHFR gene and polycystic ovary syndrome.

  2009cites this paper
• Role of the MTHFR polymorphisms in cancer risk modification and treatment.

  2009cites this paper
• The methylenetetrahydrofolate reductase C677T mutation induces cell‐specific changes in genomic DNA methylation and uracil misincorporation: A possible molecular basis for the site‐specific cancer risk modification

  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2008cites this paper
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  2008cites this paper
• B-vitamins, homocysteine and gene polymorphism in adults with fasting or post-methionine loading hyperhomocysteinemia

  2008cites this paper
• [Folic acid in physiology and pathology].

  2008cites this paper
• Kwas foliowy w fi zjologii i patologii Folic acid in physiology and pathology

  2008cites this paper
• Methylenetetrahydrofolate Reductase TT Genotype as a Predictor of Cardiovascular Risk in Hypertensive Adolescents

  2007cites this paper
• zur Veränderung des Methylierungspotenzials durch einmalige orale Homocysteinzufuhr bei gesunden Freiwilligen

  2007cites this paper
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  2007cites this paper
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  2006cites this paper
• Avaliação da relação entre o polimorfismo C677T no gene para MTHFR e a concentração plasmática de homocisteína na doença arterial coronariana

  2006cites this paper
• Methylenetetrahydrofolate reductase gene polymorphism, homocysteine and risk of macroangiopathy in Type 2 diabetes mellitus

  2006cites this paper
• artigo original Avaliação da Relação Entre o Polimorfismo C677T no Gene Para MTHFR e a Concentração Plasmática de Homocisteína na Doença Arterial Coronariana

  2006cites this paper
• Thrombophile Gerinnungsstörungen bei peripherer arterieller Verschlusskrankheit

  2006cites this paper
• [Evaluation of MTHFR C677T gene polymorphism and homocysteine level in coronary atherosclerotic disease].

  2006cites this paper
• Lack of association of methylenetetrahydrofolate reductase 677C>T mutation with coronary artery disease in a Pakistani population

  2005cites this paper
• 5,10-Methylenetetrahydrofolate Reductase Polymorphisms and the Risk of Pancreatic Cancer

  2005cites this paper
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  2005cites this paper
• Physiological Regulation of Phospholipid Methylation Alters Plasma Homocysteine in Mice*

  2005cites this paper
• Methylenetetrahydrofolate reductase polymorphism associated with susceptibility to coronary heart disease in Chinese type 2 diabetic patients.

  2005cites this paper
• Homocysteine and B vitamins.

  2005influential citation
• Coexistence of prothrombic risk factors and its relation to left ventricular thrombus in acute myocardial infarction

  2004cites this paper
• Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects

  2004cites this paper
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  2004cites this paper
• Evaluation of a shorter methionine loading test

  2004cites this paper
• The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor.

  2004cites this paper
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  2004cites this paper
• Homocysteine levels and C677T polymorphism of methylenetetrahydrofolate reductase in women with polycystic ovary syndrome.

  2003cites this paper
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  2003cites this paper
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  2003cites this paper
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  2003cites this paper
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• Update on cobalamin, folate, and homocysteine.

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  2003cites this paper
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  2002cites this paper
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  2002cites this paper
• [Homocysteine, methylenetetrahydrofolate reductase/C677T genotype and risk for coronary heart disease. The AtheroGene study].

  2002cites this paper
• Plasma homocysteine, methylenetetrahydrofolate reductase genotypes, and age at onset of symptoms of myocardial ischemia.

  2002cites this paper
• Postmethionine-load homocysteine determination for the diagnosis hyperhomocysteinaemia and efficacy of homocysteine lowering treatment regimens

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  2002cites this paper
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  2002cites this paper
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  2002cites this paper
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  2002cites this paper
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  2001cites this paper
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  2001cites this paper
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