Novel Binding Sites on Clathrin and Adaptors Regulate Distinct Aspects of Coat Assembly

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Traffic : the International Journal of Intracellular Transport

• Publication date

  2006-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1600-0854.2006.00499.xPMID 17052248
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly.

  2006influential reference
• Common principles in clathrin-mediated sorting at the Golgi and the plasma membrane.

  2005cited by this paper
• Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution.

  2005cited by this paper
• Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration.

  2004cited by this paper
• Molecular model for a complete clathrin lattice from electron cryomicroscopy

  2004influential reference
• Adaptors for clathrin coats: structure and function.

  2004influential reference
• Dual engagement regulation of protein interactions with the AP-2 adaptor alpha appendage.

  2004cited by this paper
• Structural basis for binding of accessory proteins by the appendage domain of GGAs

  2003influential reference
• Recognition of accessory protein motifs by the gamma-adaptin ear domain of GGA3.

  2003cited by this paper
• Divalent interaction of the GGAs with the Rabaptin‐5–Rabex‐5 complex

  2003cited by this paper
• Phosphoregulation of sorting signal–VHS domain interactions by a direct electrostatic mechanism

  2002cited by this paper
• Clathrin light and heavy chain interface: α‐helix binding superhelix loops via critical tryptophans

  2002cited by this paper
• The beta-appendages of the four adaptor-protein (AP) complexes: structure and binding properties, and identification of sorting nexin 9 as an accessory protein to AP-2.

  2002cited by this paper
• γ-Adaptin Appendage Domain: Structure and Binding Site for Eps15 and γ-Synergin

  2002cited by this paper
• Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain.

  2002cited by this paper
• Accessory protein recruitment motifs in clathrin-mediated endocytosis.

  2002cited by this paper
• Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif

  2002cited by this paper
• Structural basis for the accessory protein recruitment by the γ-adaptin ear domain

  2002cited by this paper
• Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin.

  2002cited by this paper
• Biological basket weaving: formation and function of clathrin-coated vesicles.

  2001cited by this paper
• Structural Requirements for Function of Yeast GGAs in Vacuolar Protein Sorting, α-Factor Maturation, and Interactions with Clathrin

  2001cited by this paper
• Binding mode prediction for a flexible ligand in a flexible pocket using multi-conformation simulated annealing pseudo crystallographic refinement.

  2001cited by this paper
• The GGAs promote ARF-dependent recruitment of clathrin to the TGN.

  2001cited by this paper
• Complete Reconstitution of Clathrin Basket Formation with Recombinant Protein Fragments: Adaptor Control of Clathrin Self‐Assembly

  2000cited by this paper
• Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin.

  2000cited by this paper
• The structure and function of the β2‐adaptin appendage domain

  2000cited by this paper
• Clathrin self-assembly is mediated by a tandemly repeated superhelix

  1999cited by this paper
• Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly.

  1999cited by this paper
• A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain.

  1999cited by this paper
• Clathrin self‐assembly is regulated by three light‐chain residues controlling the formation of critical salt bridges

  1998cited by this paper
• Association of the AP-3 adaptor complex with clathrin.

  1998influential reference
• Clathrin coats at 21 Å resolution: a cellular assembly designed to recycle multiple membrane receptors

  1998cited by this paper
• Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker.

  1998cited by this paper
• In vivo phosphorylation of adaptors regulates their interaction with clathrin

  1996cited by this paper
• Regulation of clathrin assembly and trimerization defined using recombinant triskelion hubs.

  1995cited by this paper
• A Clathrin-binding Site in the Hinge of the 2 Chain of Mammalian AP-2 Complexes (*)

  1995cited by this paper
• X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

  1992influential reference
• Folding and trimerization of clathrin subunits at the triskelion hub.

  1992cited by this paper
• The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin.

  1988cited by this paper
• Purification and characterization of two distinct complexes of assembly polypeptides from calf brain coated vesicles that differ in their polypeptide composition and kinase activities.

  1987cited by this paper

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• Role of Clathrin and Dynamin in Clathrin Mediated Endocytosis/Synaptic Vesicle Recycling and Implications in Neurological Diseases

  2022cites this paper
• Multi‐modal adaptor‐clathrin contacts drive coated vesicle assembly

  2021cites this paper
• Antagonistic regulation controls clathrin-mediated endocytosis: AP2 adaptor facilitation vs restraint from clathrin light chains.

  2021cites this paper
• Wbox2: A clathrin terminal domain–derived peptide inhibitor of clathrin-mediated endocytosis

  2020cites this paper
• Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self assembly

  2019cites this paper
• Biophysical analysis of binding interactions between clathrin and its adaptor proteins

  2017cites this paper
• Early stages of clathrin aggregation at a membrane in coarse-grained simulations.

  2017cites this paper
• Clathrin Assembly Regulated by Adaptor Proteins in Coarse-Grained Models.

  2016influential citation
• The assembly and disassembly of clathrin cages.

  2016cites this paper
• Development of an inducible model of clathrin-mediated endocytosis.

  2016influential citation
• Arc controls AMPAR endocytosis through a direct interaction with clathrin-adaptor protein 2 The Arc / AP-2 interaction mediates synaptic transmission

  2016cites this paper
• Spatial Coordination of Atg8-Lipidation in Selective and Non-selective Autophagy

  2016cites this paper
• Activity-Regulated Cytoskeleton-Associated Protein Controls AMPAR Endocytosis through a Direct Interaction with Clathrin-Adaptor Protein 2

  2016cites this paper
• The endocytic activity of the flagellar pocket in Trypanosoma brucei is regulated by an adjacent phosphatidylinositol phosphate kinase

  2016cites this paper
• A proteo-liposome system for the analysis of the intracellular interactome of membrane proteins using amyloid precursor protein as a model

  2015influential citation
• Investigating the targets and mechanisms regulating self incompatibility in Papaver rhoeas pollen

  2015cites this paper
• The endocytic activity of the flagellar pocket in Trypanosoma brucei is regulated by an adjacent phosphatidylinositol phosphate kinase

  2014cites this paper
• Non-specificity of Pitstop 2 in clathrin-mediated endocytosis

  2014cites this paper
• Contrôle de AP-1 sur le trafic de E-Cadhérine chez Drosophila melanogaster

  2014cites this paper
• Dissection of Clathrin Function Using the Small Molecule Inhibitor Pitstop®-2

  2014cites this paper
• Application of Gaussia luciferase in bicistronic and non-conventional secretion reporter constructs

  2014cites this paper
• A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing

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• NECAP 1 Regulates AP-2 Interactions to Control Vesicle Size, Number, and Cargo During Clathrin-Mediated Endocytosis

  2013cites this paper
• Arf6 Regulation of Gyrating‐Clathrin

  2013cites this paper
• Chemical-genetic disruption of clathrin function spares adaptor complex 3–dependent endosome vesicle biogenesis

  2013cites this paper
• Clathrin, adaptors and disease: insights from the yeast Saccharomyces cerevisiae.

  2013cites this paper
• Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway.

  2013cites this paper
• Analysis of the Cell Cycle Regulated Golgi Dynamics in Mammalian Cells.

  2013cites this paper
• Clathrin-Mediated Endocytosis

  2013cites this paper
• Diversity of clathrin function: new tricks for an old protein.

  2012cites this paper
• Getting in Touch with the Clathrin Terminal Domain

  2012cites this paper
• Functional Analysis of Interaction Sites on the N‐Terminal Domain of Clathrin Heavy Chain

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• Template engineering through epitope recognition: a modular, biomimetic strategy for inorganic nanomaterial synthesis.

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• Investigation of GLUT4 sorting into the insulin responsive compartment : a role for ubiquitination and deubiquitination

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• Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition.

  2011cites this paper
• Regulation of clathrin-coated vesicle nucleation

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• Roles for ADP-Ribosylation Factors in Membrane Traffic

  2010cites this paper
• Clathrin Regulates the Association of PIPKIγ661 with the AP-2 Adaptor β2 Appendage*

  2009cites this paper
• Moesin Regulates the Trafficking of Nascent Clathrin-coated Vesicles*

  2009cites this paper
• Clathrin functions in the absence of the terminal domain binding site for adaptor-associated clathrin-box motifs.

  2009influential citation
• Essential role for a long-term depression mechanism in ocular dominance plasticity

  2009cites this paper
• The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis.

  2008influential citation
• Clathrin Adaptor GGA1 Polymerizes Clathrin into Tubules*

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• Molecular Basis for Autoregulatory Interaction Between GAE Domain and Hinge Region of GGA1

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• Endocytosis: clathrin-mediated membrane budding.

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