The Upper Limb Nociceptive Reflex: Methodological Considerations in the Assessment of Central Sensitization in Humans

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Unknown venue

• Publication date

  2019-05-01

• Fields of study

  Medicine

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Enlarged Areas of Pain and Pressure Hypersensitivityby Spatially Distributed Intramuscular Injections ofLow-Dose Nerve Growth Factor.

  2019cited by this paper
• Contact heat evoked potentials: Reliable acquisition from lower extremities.

  2018influential reference
• The Influence of Placebo Analgesia Manipulations on Pain Report, the Nociceptive Flexion Reflex, and Autonomic Responses to Pain.

  2018cited by this paper
• Assessment and manifestation of central sensitisation across different chronic pain conditions

  2018influential reference
• Pain amplification—A perspective on the how, why, when, and where of central sensitization

  2018cited by this paper
• Increased Substance P Immunoreactivity in Ipsilateral Knee Cartilage of Rats Exposed to Lumbar Spine Injury

  2018cited by this paper
• Experimentally induced central sensitization evokes segmental autonomic responses in humans

  2017cited by this paper
• A Comparison of the Sensitivity of Brush Allodynia and Semmes–Weinstein Monofilament Testing in the Detection of Allodynia Within Regions of Secondary Hyperalgesia in Humans

  2017influential reference
• Pain Catastrophizing is Not Associated With Spinal Nociceptive Processing in People With Chronic Widespread Pain

  2017cited by this paper
• Knee Pain and Structural Damage as Risk Factors for Incident Widespread Pain: Data From the Multicenter Osteoarthritis Study

  2016cited by this paper
• Normative data for the segmental acquisition of contact heat evoked potentials in cervical dermatomes

  2016influential reference
• Nonparametric Tests for the Interaction in Two-way Factorial Designs Using R

  2016cited by this paper
• Ending the Opioid Epidemic - A Call to Action.

  2016cited by this paper
• Dynamic Mechanical Allodynia—One Clinical Sign, Several Mechanisms: Five Illustrative Cases

  2016cited by this paper
• Experimentally induced central sensitization in the cervical spine evokes postural stiffening strategies in healthy young adults.

  2015influential reference
• The effects of joint aspiration and intra-articular corticosteroid injection on flexion reflex excitability, quadriceps strength and pain in individuals with knee synovitis: a prospective observational study

  2015influential reference
• Introduction and validation of a less painful algorithm to estimate the nociceptive flexion reflex threshold.

  2015influential reference
• Linear mixed-effects models for within-participant psychology experiments: an introductory tutorial and free, graphical user interface (LMMgui)

  2015cited by this paper
• Pain hypersensitivity and spinal nociceptive hypersensitivity in chronic pain: prevalence and associated factors

  2015cited by this paper
• A new objective method for acquisition and quantification of reflex receptive fields

  2015cited by this paper
• A new look at arthritis management: nociceptive reflex excitability as a pain biomarker

  2015cited by this paper
• Modulation of Cervical Facet Joint Nociception and Pain Attenuates Physical and Psychological Features of Chronic Whiplash: A Prospective Study

  2015cited by this paper
• Association of Chronic Pelvic Pain and Endometriosis With Signs of Sensitization and Myofascial Pain

  2015cited by this paper
• Fitting Linear Mixed-Effects Models Using lme4

  2014influential reference
• Nociceptive neurons detect cytokines in arthritis

  2014influential reference
• Assessment of small fibers using evoked potentials

  2014influential reference
• MUSCULOSKELETAL SECTION Original Research Article Cervical Radiofrequency Neurotomy Reduces Central Hyperexcitability and Improves Neck Movement in Individuals with Chronic Whiplash

  2014influential reference
• Determinants of increased opioid-related mortality in the United States and Canada, 1990-2013: a systematic review.

  2014influential reference
• Withdrawal reflexes in the upper limb adapt to arm posture and stimulus location

  2014influential reference
• A Kenward-Roger approximation and parametric bootstrap methods for tests in linear mixed models: The R Package pbkrtest

  2014cited by this paper
• Central sensitization in spinal cord injured humans assessed by reflex receptive fields.

  2014influential reference
• Analysis of muscle fiber conduction velocity enables reliable detection of surface EMG crosstalk during detection of nociceptive withdrawal reflexes

  2013cited by this paper
• A comparison of physical and psychological features of responders and non-responders to cervical facet blocks in chronic whiplash

  2013cited by this paper
• Reflex receptive fields are enlarged in patients with musculoskeletal low back and neck pain

  2013influential reference
• Habituation of the nociceptive flexion reflex is dependent on inter-stimulus interval and stimulus intensity.

  2013influential reference
• Assessment of pain response in capsaicin-induced dynamic mechanical allodynia using a novel and fully automated brushing device.

  2013cited by this paper
• Improving the acquisition of nociceptive evoked potentials without causing more pain

  2013cited by this paper
• The effect of topical capsaicin-induced sensitization on heat-evoked cutaneous vasomotor responses.

  2013cited by this paper
• Evidence for central sensitization in chronic whiplash: A systematic literature review

  2013cited by this paper
• pinal neuronal plasticity is evident within 1 day after a painful cervical acet joint injury

  2013cited by this paper
• Reorganization of multi-muscle and joint withdrawal reflex during arm movements in post-stroke hemiparetic patients.

  2012cited by this paper
• The effect of nerve compression and capsaicin on contact heat-evoked potentials related to Aδ- and C-fibers.

  2012cited by this paper
• Adaptive behaviour of the spinal cord in the transition from quiet stance to walking

  2012cited by this paper
• Relationships between Pain, Function and Radiographic Findings in Osteoarthritis of the Knee: A Cross-Sectional Study

  2012cited by this paper
• Unravelling the Mystery of Capsaicin: A Tool to Understand and Treat Pain

  2012influential reference
• Increased contact heat pain and shortened latencies of contact heat evoked potentials following capsaicin-induced heat hyperalgesia.

  2012cited by this paper
• What is different about spinal pain?

  2012cited by this paper
• Nonparametric analysis of longitudinal data in factorial experiments

  2012influential reference
• Comparisons of treatment means when factors do not interact in two-factorial studies

  2011cited by this paper
• Central sensitization: Implications for the diagnosis and treatment of pain

  2011influential reference
• Central hyperexcitability as measured with nociceptive flexor reflex threshold in chronic musculoskeletal pain: A systematic review

  2011influential reference
• Reliability and validity of a brief method to assess nociceptive flexion reflex (NFR) threshold.

  2011cited by this paper
• The need for a Canadian pain strategy.

  2011influential reference
• Pain catastrophizing is related to temporal summation of pain but not temporal summation of the nociceptive flexion reflex

  2011influential reference
• The prevalence of chronic pain in Canada.

  2011influential reference
• Analysis of hyperalgesia time courses in humans after painful electrical high‐frequency stimulation identifies a possible transition from early to late LTP‐like pain plasticity

  2011cited by this paper
• Sensitization in patients with painful knee osteoarthritis

  2010cited by this paper
• The Canadian STOP-PAIN project – Part 1: Who are the patients on the waitlists of multidisciplinary pain treatment facilities?

  2010influential reference
• Muscle Pain: Understanding the Mechanisms

  2010cited by this paper
• Generalized expansion of nociceptive reflex receptive fields in chronic pain patients

  2010influential reference
• Differential development of sensory hypersensitivity and a measure of spinal cord hyperexcitability following whiplash injury

  2010cited by this paper
• The nociceptive withdrawal reflex: Normative values of thresholds and reflex receptive fields

  2010influential reference
• Capsaicin-induced central sensitization evokes segmental increases in trigger point sensitivity in humans.

  2010influential reference
• Heightened flexor withdrawal response in individuals with knee osteoarthritis is modulated by joint compression and joint mobilization.

  2010influential reference
• Long‐term facilitation of nociceptive withdrawal reflexes following low‐frequency conditioning electrical stimulation: A new model for central sensitization in humans

  2010cited by this paper
• A protocol for data exploration to avoid common statistical problems

  2010cited by this paper
• Cervical lateral glide increases nociceptive flexion reflex threshold but not pressure or thermal pain thresholds in chronic whiplash associated disorders: A pilot randomised controlled trial.

  2010influential reference
• MAP kinase and pain.

  2009cited by this paper
• Characteristics of the nociceptive withdrawal response elicited under aware and unaware conditions.

  2009cited by this paper
• Vascular and psychophysical effects of topical capsaicin application to orofacial tissues.

  2009cited by this paper
• Somatosensory profiles in subgroups of patients with myogenic temporomandibular disorders and fibromyalgia syndrome

  2009cited by this paper
• Psychophysical and functional imaging evidence supporting the presence of central sensitization in a cohort of osteoarthritis patients.

  2009cited by this paper
• Heightened flexor withdrawal responses in subjects with knee osteoarthritis.

  2009influential reference
• New method for quantification and statistical analysis of nociceptive reflex receptive fields in humans.

  2009influential reference
• c-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?

  2009cited by this paper
• Psychologic Factors Are Related to Some Sensory Pain Thresholds but Not Nociceptive Flexion Reflex Threshold in Chronic Whiplash

  2008cited by this paper
• Mixed-effects modeling with crossed random effects for subjects and items

  2008influential reference
• Capsaicin: A review of its pharmacology and clinical applications

  2008cited by this paper
• Reliability of the nociceptive flexor reflex (RIII) threshold and association with Pain threshold

  2008cited by this paper
• Nociceptive flexion reflex thresholds and pain during rest and computer game play in patients with hypertension and individuals at risk for hypertension.

  2007cited by this paper
• Defining the nociceptive flexion reflex (NFR) threshold in human participants: A comparison of different scoring criteria

  2007cited by this paper
• Usefulness and limitations of quantitative sensory testing: clinical and research application in neuropathic pain states.

  2007cited by this paper
• Temporal summation of second pain and its maintenance are useful for characterizing widespread central sensitization of fibromyalgia patients.

  2007influential reference
• Abnormal Modulatory Influence of Diffuse Noxious Inhibitory Controls in Migraine and Chronic Tension-Type Headache Patients

  2006cited by this paper
• Kinematic and Electromyographic Study of the Nociceptive Withdrawal Reflex in the Upper Limbs during Rest and Movement

  2006influential reference
• Intradermal Capsaicin Causes Dose-Dependent Pain, Allodynia, and Hyperalgesia in Humans

  2006influential reference
• Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Standardized protocol and reference values

  2006influential reference
• Frequency of headache is related to sensitization: A population study

  2006cited by this paper
• Affective modulation of nociception at spinal and supraspinal levels.

  2005cited by this paper
• The lower limb flexion reflex in humans.

  2005influential reference
• Sex differences in nociceptive withdrawal reflex and pain perception

  2005cited by this paper
• Assessment of opiate modulation of pain and nociceptive responding in young adults with a parental history of hypertension.

  2005cited by this paper
• Facilitation and inhibition of withdrawal reflexes following repetitive stimulation: electro‐ and psychophysiological evidence for activation of noxious inhibitory controls in humans

  2005cited by this paper
• The influence of acute anxiety on assessment of nociceptive flexion reflex thresholds in healthy young adults

  2005cited by this paper
• Dynamic mechanical allodynia: On the relationship between temporo‐spatial stimulus parameters and evoked pain in patients with peripheral neuropathy

  2005influential reference
• The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels

  2004influential reference
• Electrophysiological and psychophysical quantification of temporal summation in the human nociceptive system

  2004influential reference
• Altered pain-related behaviors and spinal neuronal responses produced by s.c. injection of melittin in rats.

  2004cited by this paper
• Effects of diffuse noxious inhibitory controls on temporal summation of the RIII reflex in humans

  2004cited by this paper
• Mental stress inhibits pain perception and heart rate variability but not a nociceptive withdrawal reflex.

  2004cited by this paper

• No citing papers are available for this paper.