Recent advances in the study of renin and angiotensinogen genes: from molecules to the whole body.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Hypertension Research

• Publication date

  1995-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1291/HYPRES.18.7PMID 7584914
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular variant of angiotensinogen gene is associated with coronary atherosclerosis.

  1995cited by this paper
• Transgenes, hypotheses, and hypertension.

  1994cited by this paper
• Cardiac renin and angiotensins. Uptake from plasma versus in situ synthesis.

  1994cited by this paper
• Hypertension in the transgenic rat TGR(mRen-2)27 may be due to enhanced kinetics of the reaction between mouse renin and rat angiotensinogen.

  1994cited by this paper
• Mechanism of cAMP regulation of renin gene transcription by proximal promoter.

  1994cited by this paper
• Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice.

  1994cited by this paper
• X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen.

  1994cited by this paper
• Molecular mechanism of transcriptional activation of angiotensinogen gene by proximal promoter.

  1994cited by this paper
• Molecular Variants of the Angiotensinogen Gene and Hypertension in a Japanese Population

  1994cited by this paper
• Renin is not synthesized by cardiac and extrarenal vascular tissues. A review of experimental evidence.

  1994cited by this paper
• Angiotensinogen: An Acute‐Phase Protein?

  1994cited by this paper
• Angiotensinogen as a risk factor for essential hypertension in Japan.

  1994cited by this paper
• cis-regulatory elements and trans-acting factors directing basal and cAMP-stimulated human renin gene expression in chorionic cells.

  1994cited by this paper
• Molecular mechanism of adipogenic activation of the angiotensinogen gene.

  1994cited by this paper
• Angiotensinogen-deficient mice with hypotension.

  1994cited by this paper
• Targeting gene expression to specific cardiovascular cell types in transgenic mice.

  1993cited by this paper
• Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes.

  1993cited by this paper
• Tissue renin-angiotensin systems. Their role in cardiovascular disease.

  1993cited by this paper
• Use of Transgenic Animals in the Study of Neuropeptide Genes

  1993cited by this paper
• Cyclic AMP selectively increases renin mRNA stability in cultured juxtaglomerular granular cells.

  1993cited by this paper
• Major approaches for generating and analyzing transgenic mice. An overview.

  1993cited by this paper
• Angiotensin II stimulates the synthesis of angiotensinogen in hepatocytes by inhibiting adenylylcyclase activity and stabilizing angiotensinogen mRNA.

  1993cited by this paper
• Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro.

  1993cited by this paper
• Activation of mouse renin promoter by cAMP and c-Jun in a kidney-derived cell line.

  1993cited by this paper
• Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression.

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• Identification and characterization of adenosine A1 receptor-cAMP system in human glomeruli.

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• Proximal and core DNA elements are required for efficient angiotensinogen promoter activation during adipogenic differentiation.

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• A molecular variant of angiotensinogen associated with preeclampsia

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• Promoter activity of human renin 5'-flanking DNA sequences is activated by the pituitary-specific transcription factor Pit-1.

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• Renin mRNA quantification using polymerase chain reaction in cultured juxtaglomerular cells. Short-term effects of cAMP on renin mRNA and secretion.

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• Vascular Injury Induces Angiotensinogen Gene Expression in the Media and Neointima

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• Tissue specificity of renin promoter activity and regulation in mice.

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• Regulation and functional consequences of angiotensinogen gene expression.

  1992cited by this paper
• Lewis K. Dahl Memorial Lecture. The renin system and four lines fo hypertension research. Nephron heterogeneity, the calcium connection, the prorenin vasodilator limb, and plasma renin and heart attack.

  1992cited by this paper
• Regulated tissue- and cell-specific expression of the human renin gene in transgenic mice.

  1992cited by this paper
• High blood pressure in transgenic mice carrying the rat angiotensinogen gene.

  1992cited by this paper
• Abnormalities of glucocorticoid metabolism and the renin-angiotensin system: a four-corners approach to the identification of genetic determinants of blood pressure.

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• Renin-angiotensin system : a dual tissue and hormonal system for cardiovascular control

  1992cited by this paper
• Structure and expression of the mouse angiotensinogen gene.

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• A combination of upstream and proximal elements is required for efficient expression of the mouse renin promoter in cultured cells.

  1992cited by this paper
• Evidence for tissue-specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure.

  1992cited by this paper
• X-ray analyses of peptide–inhibitor complexes define the structural basis of specificity for human and mouse renins

  1992cited by this paper
• Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes.

  1992cited by this paper
• Species-specific induction of angiotensinogen mRNA in transgenic mouse liver during acute phase reaction.

  1992cited by this paper
• Molecular biology of renin II: Gene control by messenger RNA, transfection and transgenic studies

  1992cited by this paper
• [Molecular biology in renin angiotensin system].

  1992cited by this paper
• Role of Tissue Renin in the Pathophysiology of Hypertension in TGR(mREN2)27 Rats

  1992cited by this paper
• Tissue-specific nutritional regulation of angiotensinogen in adipose tissue.

  1992cited by this paper
• Molecular biology of renin I: Gene and protein structure, synthesis and processing

  1992cited by this paper
• Juxtaglomerular cells cultured on a reconstituted basement membrane.

  1992cited by this paper
• Identification of cis-acting DNA elements involved in the regulation of angiotensinogen gene expression.

  1992cited by this paper
• Targeted integration of the Ren-1D locus in mouse embryonic stem cells.

  1992cited by this paper
• Adrenal and circulating renin-angiotensin system in stroke-prone hypertensive rats.

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• Molecular basis of human hypertension: role of angiotensinogen.

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• Molecular Biology of Hypertension

  1991cited by this paper
• Structure, Expression, and Regulation of the Murine Renin Genes

  1991cited by this paper
• Molecular mechanism of tissue-specific regulation of mouse renin gene expression by cAMP. Identification of an inhibitory protein that binds nuclear transcriptional factor.

  1991cited by this paper
• Differential Regulation of Angiotensin Peptide Levels in Plasma and Kidney of the Rat

  1991cited by this paper
• Localization and differential regulation of angiotensinogen mRNA expression in the vessel wall.

  1991cited by this paper
• Human Prorenin

  1991cited by this paper
• Brain and Liver Angiotensinogen Messenger RNA in Genetic Hypertensive and Normotensive Rats

  1991cited by this paper
• Cell type-specific expression of the human renin gene.

  1991cited by this paper
• Hormonal correlates of weight loss associated with blood pressure reduction.

  1991cited by this paper
• Transient expression analyses of DNA extending 2.4 kb upstream of the human renin gene.

  1991cited by this paper
• Transgenic Animals New Approaches to Hypertension Research

  1991cited by this paper
• DuP 753 Is a Specific Antagonist for the Angiotensin Receptor

  1991cited by this paper
• Expression of the human angiotensinogen gene in transgenic mice and transfected cells.

  1991cited by this paper
• Transgenic Rats: New Animal Models in Hypertension Research Invited Lecture

  1991cited by this paper
• Molecular Biology of Angiotensinogen

  1991cited by this paper
• Human renin in transgenic mouse kidney is localized to juxtaglomerular cells.

  1991cited by this paper
• Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene

  1990cited by this paper
• ES‐8891, an Orally Active Inhibitor of Human Renin

  1990cited by this paper
• Tissue and cell specific expression of a renin promoter-reporter gene construct in transgenic mice.

  1990cited by this paper
• The permissive role of glucocorticoids on interleukin-1 stimulation of angiotensinogen gene transcription is mediated by an interaction between inducible enhancers.

  1990cited by this paper
• Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct.

  1990cited by this paper
• Regulation of human renin expression in chorion cell primary cultures.

  1990cited by this paper
• Renin release and gene expression in intact rat kidney microvessels and single cells.

  1990cited by this paper
• Generation of transgenic mice with elevated blood pressure by introduction of the rat renin and angiotensinogen genes.

  1990cited by this paper
• Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats.

  1990cited by this paper
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  1990cited by this paper
• Structure and expression of the human angiotensinogen gene. Identification of a unique and highly active promoter.

  1990cited by this paper
• A family of constitutive C/EBP‐like DNA binding proteins attenuate the IL‐1 alpha induced, NF kappa B mediated trans‐activation of the angiotensinogen gene acute‐phase response element.

  1990cited by this paper
• Angiotensin II can regulate gene expression by the AP-1 binding sequence via a protein kinase C-dependent pathway.

  1990cited by this paper
• Expression of murine renin genes during fetal development.

  1990cited by this paper
• The human renin gene in transgenic mice.

  1990cited by this paper
• Extra-renal transcription of the renin genes in multiple tissues of mice and rats.

  1989cited by this paper
• Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution.

  1989cited by this paper
• Tissue-specific expression of the human renin gene in transgenic mice.

  1989cited by this paper
• Tissue‐specific and hormonal regulation of angiotensinogen minigenes in transgenic mice.

  1989cited by this paper
• Multiple cis-acting DNA regulatory elements mediate hepatic angiotensinogen gene expression.

  1989cited by this paper
• Regulation of angiotensinogen gene.

  1989cited by this paper
• The B subunit of coagulation factor XIII is linked to renin and the Duffy blood group to alpha-spectrin on human chromosome 1.

  1989cited by this paper
• Identification of negative and positive regulatory elements in the human renin gene.

  1989cited by this paper
• A widespread abnormality of renin gene expression in the spontaneously hypertensive rat: modulation in some tissues with the development of hypertension.

  1989cited by this paper
• Inhibitory Effect of Human Atrial Natriuretic Peptide on Cyclic AMP Levels in Microdissected Human Glomeruli

  1988cited by this paper
• Molecular biology of the renin-angiotensin system.

  1988cited by this paper
• Nucleotide sequence of rat renin cDNA.

  1988cited by this paper
• Circulating versus local renin‐angiotensin system in cardiovascular homeostasis

  1988cited by this paper

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