CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  American Journal of Pathology

• Publication date

  2005-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0002-9440(10)62289-4PMID 15743780PMCID PMC1780139
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanisms of pulmonary fibrosis.

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  2003influential reference
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  2001influential reference
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  2001cited by this paper
• Idiopathic pulmonary fibrosis: relationship between histopathologic features and mortality.

  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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