Cyclosporine, methotrexate, and prednisone compared with cyclosporine and prednisone for prophylaxis of acute graft-versus-host disease.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  New England Journal of Medicine

• Publication date

  1993-10-21

• Fields of study

  Medicine

• Identifiers
  DOI 10.1056/NEJM199310213291703PMID 8413388
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• EXTENDED FOLLOW‐UP IN 212 LONG‐TERM ALLOGENEIC BONE MARROW TRANSPLANT SURVIVORS ISSUES OF QUALITY OF LIFE

  1993cited by this paper
• A prospective randomized comparison of total body irradiation-etoposide versus busulfan-cyclophosphamide as preparatory regimens for bone marrow transplantation in patients with leukemia who were not in first remission: a Southwest Oncology Group study.

  1993cited by this paper
• Acute graft-versus-host disease: analysis of risk factors after allogeneic marrow transplantation and prophylaxis with cyclosporine and methotrexate.

  1992cited by this paper
• Allogeneic bone marrow transplantation for high-risk acute lymphoblastic leukemia during first complete remission

  1991cited by this paper
• A randomized, controlled trial of prophylactic ganciclovir for cytomegalovirus pulmonary infection in recipients of allogeneic bone marrow transplants; The City of Hope-Stanford-Syntex CMV Study Group.

  1991cited by this paper
• Allogeneic bone marrow transplantation for high-risk acute lymphoblastic leukemia during first complete remission.

  1991cited by this paper
• A Randomized, Controlled Trial of Prophylactic Ganciclovir for Cytomegalovirus Pulmonary Infection in Recipients of Allogeneic Bone Marrow Transplants

  1991cited by this paper
• A retrospective analysis of therapy for acute graft-versus-host disease: initial treatment.

  1990cited by this paper
• What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants?

  1990cited by this paper
• Immunomodulatory and antimicrobial efficacy of intravenous immunoglobulin in bone marrow transplantation.

  1990cited by this paper
• A retrospective analysis of therapy for acute graft-versus-host disease: secondary treatment.

  1990cited by this paper
• Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial.

  1989cited by this paper
• A novel technique for plasma CsA determination--application to drug monitoring during transplantation.

  1989cited by this paper
• Cyclosporine v methotrexate for graft-v-host disease prevention in patients given marrow grafts for leukemia: long-term follow-up of three controlled trials

  1988cited by this paper
• Cyclosporine v methotrexate for graft-v-host disease prevention in patients given marrow grafts for leukemia: long-term follow-up of three controlled trials.

  1988cited by this paper
• Total body irradiation and high-dose etoposide: a new preparatory regimen for bone marrow transplantation in patients with advanced hematologic malignancies.

  1987cited by this paper
• Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen.

  1987cited by this paper
• Impact of T-cell depletion on outcome of allogeneic bone-marrow transplantation for standard-risk leukaemias.

  1987cited by this paper
• A prospective randomized study of acute graft-v-host disease in 107 patients with leukemia: methotrexate/prednisone v cyclosporine A/prednisone.

  1987cited by this paper
• Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen

  1987cited by this paper
• Total body irradiation and high-dose etoposide: a new preparatory regimen for bone marrow transplantation in patients with advanced hematologic malignancies [published erratum appears in Blood 1987 Jun;69(6):1789]

  1987cited by this paper
• Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia.

  1986cited by this paper
• Marrow transplantation for severe aplastic anemia: methotrexate alone compared with a combination of methotrexate and cyclosporine for prevention of acute graft-versus-host disease.

  1986cited by this paper
• Cyclosporine as prophylaxis for graft-versus-host disease: a randomized study in patients undergoing marrow transplantation for acute nonlymphoblastic leukemia.

  1985cited by this paper
• Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts.

  1985cited by this paper
• Graft‐versus‐Host Disease in Dog and Man: The Seattle Experience

  1985cited by this paper
• Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts

  1985cited by this paper
• A randomized study of the prevention of acute graft-versus-host disease.

  1982cited by this paper
• CLINICAL MANIFESTATIONS OF GRAFT‐VERSUS-HOST DISEASE IN HUMAN RECIPIENTS OF MARROW FROM HL‐A-MATCHED SIBLING DONOR,S

  1974cited by this paper

• Dosage Recommendations for Off-label Use of Mycophenolate Mofetil in Pediatric Patients with Thalassemia Undergoing Hematopoietic Stem Cell Transplantation: An Approach Based on Population Pharmacokinetic Studies

  2025cites this paper
• Comparing drug combinations for graft-versus-host disease prophylaxis using the U.S. Food and Drug Administration Adverse Event Reporting System

  2025cites this paper
• Outcomes of human leukocyte antigen matched sibling transplant from consanguineous versus non-consanguineous parents, a single center experience

  2025cites this paper
• Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review

  2023cites this paper
• Short-term methotrexate plus cyclosporine for graft-versus-host disease prophylaxis after single-unit cord blood transplantation following reduced-intensity conditioning

  2022cites this paper
• Post-Transplantation Cyclophosphamide Uniquely Restrains Alloreactive CD4+ T-Cell Proliferation and Differentiation After Murine MHC-Haploidentical Hematopoietic Cell Transplantation

  2022cites this paper
• Haploidentical Peripheral Stem Cell Transplantation for Young Patients with Severe Aplastic Anemia Using Post-Transplantation Cyclophosphamide and Methotrexate.

  2021cites this paper
• Immunosuppressive Therapy and Immunomodulation in Stem Cell Transplantation

  2020cites this paper
• Highlighting the Prognostic Importance of Measurable Residual Disease Among Acute Myeloid Leukemia Risk Factors

  2020cites this paper
• Use of Thrombopoietin Receptor Agonists in Prolonged Thrombocytopenia after Hematopoietic Stem Cell Transplantation.

  2019cites this paper
• Central Roles of OX40L–OX40 Interaction in the Induction and Progression of Human T Cell–Driven Acute Graft-versus-Host Disease

  2019cites this paper
• Effect of the severity of acute graft-versus-host disease on physical function after allogeneic hematopoietic stem cell transplantation

  2019cites this paper
• Acute Graft-Versus-Host Disease: Diagnosis, Prophylaxis, and Treatment

  2018cites this paper
• A randomized study of cyclosporine and methotrexate with or without methylprednisolone for the prevention of graft‐versus‐host disease: Improved long‐term survival with triple prophylaxis

  2018cites this paper
• Special Care of Blood and Marrow Hematopoietic Cell Transplant Recipient

  2018cites this paper
• Complications and Results

  2017cites this paper
• Evaluation of IL2 and HLA on the Homeostasis and Function of Human CD4 and CD8 T Cells

  2017cites this paper
• Acute Graft Versus Host Disease: A Comprehensive Review.

  2017cites this paper
• Calcineurin inhibitor-free GVHD prophylaxis with sirolimus and mycophenolate mofetil combination

  2017cites this paper
• Granulocyte-macrophage colony-stimulating factor (GM-CSF) counteracts the inhibiting effect of monocytes on natural killer (NK) cells

  2017cites this paper
• Tissue tolerance: a distinct concept to control acute GVHD severity.

  2017cites this paper
• Tacrolimus versus cyclosporine A for prevention of graft versus host disease after stem cell transplantation

  2016cites this paper
• Introduction to Hematopoietic Cell Transplantation

  2016cites this paper
• Higher plasma bilirubin predicts veno-occlusive disease in early childhood undergoing hematopoietic stem cell transplantation with cyclosporine.

  2016cites this paper
• Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics of Immunosuppressants in Allogeneic Hematopoietic Cell Transplantation: Part II

  2016cites this paper
• Graft-Versus-Host Disease Prevention: Corticosteroids Revisited.

  2016cites this paper
• Cyclosporine I.V. Dose Adjustment in Patients with Hematopoietic Stem Cell Transplantation

  2016cites this paper
• Unmanipulated Haploidentical Reduced-Intensity Stem Cell Transplantation Using Fludarabine, Busulfan, Low-Dose Antithymocyte Globulin, and Steroids for Patients in Non-Complete Remission or at High Risk of Relapse: A Prospective Multicenter Phase I/II Study in Japan.

  2015cites this paper
• Pharmacokinetics, Pharmacodynamics and Pharmacogenomics of Immunosuppressants in Allogeneic Haematopoietic Cell Transplantation: Part I

  2015cites this paper
• Sirolimus plus calcineurin inhibitors and methotrexate: is more necessarily better?

  2015cites this paper
• Safety and efficacy of low-dose methotrexate for pediatric patients with steroid-refractory acute graft-versus-host disease after hematopoietic stem cell transplantation

  2014cites this paper
• Developing T cell cancer immunotherapy in the dog with lymphoma.

  2014cites this paper
• Achievement of Transplantation Tolerance: Novel Approaches and Mechanistic Insights

  2014cites this paper
• Differential Diagnosis of Thrombocytopenia in Hematopoietic Stem Cell Transplant Patients

  2014cites this paper
• Rôle des lymphocytes Th17 et des cellules dendritiques plasmocytoïdes dans la réaction aiguë du greffon contre l'hôte après allogreffe de cellules souches hématopoïétiques

  2014cites this paper
• Graft-Versus-Host Disease Prophylaxis after Transplantation: A Network Meta-Analysis

  2014influential citation
• Complications of Allogeneic Hematopoietic Stem Cell Transplantation

  2014cites this paper
• Advances in the treatment of acute graft-versus-host disease

  2013cites this paper
• Chronic Phase of Chronic Myeloid Leukemia: Developed for the American Interferon, and Allogeneic Bone Marrow Transplantation in Treating the An Evidence-Based Analysis of the Effect of Busulfan, Hydroxyurea,

  2013cites this paper
• Successful allo-HSCT with a minimal myeloablative conditioning regimen in an adult patient with Fanconi’s anemia

  2012cites this paper
• Intestinal Graft-Versus-Host Disease

  2012cites this paper
• Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival.

  2012cites this paper
• Are we making progress in GVHD prophylaxis and treatment?

  2012cites this paper
• Cyclosporin

  2012cites this paper
• Choosing a Regimen for Prophylaxis of Graft-versus-Host Disease

  2012cites this paper
• Higher CD3+ and CD34+ cell doses in the graft increase the incidence of acute GVHD in children receiving BMT for thalassemia

  2012cites this paper
• Novel Pharmacotherapeutic Approaches to Prevention and Treatment of GVHD

  2012cites this paper
• Innate immune activation by the viral PAMP poly I:C potentiates pulmonary graft-versus-host disease after allogeneic hematopoietic cell transplant.

  2011cites this paper
• Influence of immunosuppressive treatment on risk of recurrent malignancy after allogeneic hematopoietic cell transplantation.

  2011cites this paper
• Graft-vs-host disease following allogeneic hematopoietic cell transplantation.

  2011cites this paper
• Pathophysiology, prevention, and treatment of acute graft-versus-host disease

  2011cites this paper
• Chronic graft versus host disease: a scleroderma-like case report

  2011cites this paper
• donors graft-versus-host disease after marrow transplantation from unrelated methotrexate and cyclosporine for prophylaxis of acute Phase 3 study comparing methotrexate and tacrolimus with

  2011cites this paper
• with chronic myelogenous leukemia in chronic phase preparatory regimen for bone marrow transplantation for 94 patients Fractionated total-body irradiation and high-dose etoposide as a

  2011cites this paper
• single-center study disease after marrow transplantation from HLA-matched siblings: a methylprednisolone for the prevention of acute graft-versus-host Tacrolimus (FK506) alone or in combination with methotrexate or

  2011cites this paper
• Cyclolinopeptide derivatives modify methotrexate-induced suppression of the humoral immune response in mice.

  2011cites this paper
• Methotrexate Reduces the Incidence of Severe Acute Graft-versus-Host Disease without Increasing the Risk of Relapse after Reduced-Intensity Allogeneic Stem Cell Transplantation from Unrelated Donors.

  2011cites this paper
• [Allogeneic hematopoietic stem cell transplantations].

  2011cites this paper
• factor for graft-versus-host disease Polymorphism of adhesion molecule CD31 is not a significant risk

  2011cites this paper
• Allogreffes de cellules souches hématopoïétiques

  2011cites this paper
• Hepatobiliary Complications of Hematopoietic Cell Transplantation

  2011cites this paper
• Acute Graft Versus Host Disease: Prophylaxis

  2010cites this paper
• Étude des mécanismes d'action de la PhotoChimiothérapie Extra-corporelle chez l'Homme

  2010cites this paper
• Reconstitution immunitaire et immunothérapie adoptive anti-virales après allogreffe de cellules souches hématopoiétiques

  2010cites this paper
• Pulmonary, gonadal, and central nervous system status after bone marrow transplantation for sickle cell disease.

  2010cites this paper
• Should methotrexate plus calcineurin inhibitors be considered standard of care for prophylaxis of acute graft-versus-host disease?

  2010cites this paper
• Thrombocytopenia and hemostatic disorders in chronic graft versus host disease

  2009cites this paper
• Etanercept, mycophenolate, denileukin, or pentostatin plus corticosteroids for acute graft-versus-host disease: a randomized phase 2 trial from the Blood and Marrow Transplant Clinical Trials Network.

  2009cites this paper
• Prophylaxis regimens for GVHD: systematic review and meta-analysis

  2009cites this paper
• Marrow Transplant Clinical Trials Network phasecorticosteroids for acute graft-versus-host disease : a randomized Etanercept , mycophenolate , denileukin , or pentostatin plus

  2009cites this paper
• Pharmacologic Prevention of Acute Graft‐Versus‐Host Disease

  2009cites this paper
• First-line therapy for chronic graft-versus-host disease that includes low-dose methotrexate is associated with a high response rate.

  2009cites this paper
• A phase III study of infliximab and corticosteroids for the initial treatment of acute graft-versus-host disease.

  2009cites this paper
• A glucocorticoid amplifies IL-2-induced selective expansion of CD4(+)CD25(+)FOXP3(+) regulatory T cells in vivo and suppresses graft-versus-host disease after allogeneic lymphocyte transplantation.

  2009cites this paper
• Longitudinal assessment of morbidity and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation: retrospective analysis of a multicenter phase III study.

  2009cites this paper
• INFLAMMATION AND IMMUNOMODULATION

  2009cites this paper
• Emerging drugs for acute graft-versus-host disease

  2009cites this paper
• Rapamycin for Refractory Acute Graft-Versus-Host Disease

  2009cites this paper
• Randomised trials of Graft versus Host Disease prophylaxis in haemopoietic stem cell transplantation.

  2008cites this paper
• Current and future approaches for control of graft-versus-host disease

  2008cites this paper
• Low-dose MTX for the treatment of acute and chronic graft-versus-host disease in children

  2008cites this paper
• Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) bone marrow transplantation using only pharmacological GVHD prophylaxis.

  2008cites this paper
• Novel drugs for the prevention and treatment of acute GVHD.

  2008cites this paper
• SAFETY OF HEMATOPOIETIC STEM CELL TRANSPLANTATION IN CHILDREN LESS THAN THREE YEARS OF AGE

  2008cites this paper
• Cyclosporin, methotrexate and prednisolone for graft-versus-host disease prophylaxis in allogeneic peripheral blood progenitor cell transplants

  2008cites this paper
• Acute Graft-versus-Host Disease

  2008cites this paper
• Individualisation of mycophenolate mofetil therapy

  2007cites this paper
• Pharmacokinetics of Mycophenolate Mofetil in Hematopoietic Stem Cell Transplant Recipients

  2007cites this paper
• Impact of postgrafting immunosuppressive regimens on nonrelapse mortality and survival after nonmyeloablative allogeneic hematopoietic stem cell transplant using the fludarabine and low-dose total-body irradiation 200-cGy.

  2007cites this paper
• Risk assessment in haematopoietic stem cell transplantation: GvHD prevention and treatment.

  2007cites this paper
• The management and outcome of chronic graft‐versus‐host disease

  2007cites this paper
• Methotrexate inhibits integrin adhesion molecules in the mouse model of pleurisy induced by carrageenan

  2007cites this paper
• Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) stem cell transplantation using nonmyeloablative conditioning.

  2006cites this paper
• Assessment of converting from intravenous to oral administration of cyclosporin A in pediatric allogeneic hematopoietic stem cell transplant recipients

  2006cites this paper
• Biologic Principles of Hematopoietic Stem Cell Transplantation

  2006cites this paper
• Steroid myopathy in patients with acute graft-versus-host disease treated with high-dose steroid therapy

  2006cites this paper
• Prevention of immune responses to human erythropoietin in cynomolgus monkeys (Macaca fascicularis).

  2006cites this paper
• High-dose carmustine, etoposide, and cyclophosphamide followed by allogeneic hematopoietic cell transplantation for non-Hodgkin lymphoma.

  2006cites this paper
• Extending Postgrafting Cyclosporine Decreases the Risk of Severe Graft-versus-Host Disease after Nonmyeloablative Hematopoietic Cell Transplantation

  2006cites this paper
• Extracorporeal photopheresis for acute and chronic graft-versus-host disease: does it work?

  2006cites this paper