Protein translocation: tunnel vision.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Cell

• Publication date

  1998-02-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0092-8674(00)80930-7PMID 9476897
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration.

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• The E. coli signal recognition particle is required for the insertion of a subset of inner membrane proteins.

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• Molecular mechanism of membrane protein integration into the endoplasmic reticulum.

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• Sequence-specific alteration of the ribosome-membrane junction exposes nascent secretory proteins to the cytosol.

  1996cited by this paper
• Snapshots of membrane-translocating proteins.

  1996cited by this paper
• Escherichia coli Preprotein Translocase*

  1996cited by this paper
• Mechanism of Polypeptide Translocation into the Endoplasmic Reticulum*

  1996cited by this paper
• Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes.

  1996cited by this paper
• Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation.

  1996cited by this paper
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  1996cited by this paper
• The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process.

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• Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane

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• Directionality in protein translocation across membranes: the N-tail phenomenon.

  1995cited by this paper
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• The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum

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• Protein translocation genetics

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• Membrane insertion and assembly of ductin: a polytopic channel with dual orientations.

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• Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p.

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• Reconstitution of a protein translocation system containing purified SecY, SecE, and SecA from Escherichia coli.

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• Genetic analysis of protein export in Escherichia coli.

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• The purified E. coli integral membrane protein SecY/E is sufficient for reconstitution of SecA-dependent precursor protein translocation.

  1990cited by this paper
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• On the transfer of integral proteins into membranes.

  1987cited by this paper
• Genetic analysis of protein export in Escherichia coli K12.

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• Intracellular protein topogenesis.

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• Intracellular protein topogenesis.

  1980cited by this paper

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