MK-801-induced impairments on the trial-unique, delayed nonmatching-to-location task in rats: effects of acute sodium nitroprusside

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Psychopharmacology

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1007/s00213-016-4451-2PMID 27725997
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effects of the metabotropic glutamate receptor 5 positive allosteric modulator CDPPB on rats tested with the paired associates learning task in touchscreen-equipped operant conditioning chambers.

  2016cited by this paper
• Histamine H3 receptor antagonists display antischizophrenic activities in rats treated with MK-801

  2016cited by this paper
• Changes in cortical N-methyl-d-aspartate receptors and post-synaptic density protein 95 in schizophrenia, mood disorders and suicide

  2016cited by this paper
• A review of vulnerability and risks for schizophrenia: Beyond the two hit hypothesis.

  2016cited by this paper
• The nitric oxide donor sodium nitroprusside attenuates recognition memory deficits and social withdrawal produced by the NMDA receptor antagonist ketamine and induces anxiolytic-like behaviour in rats

  2016influential reference
• Clarifying the role of pattern separation in schizophrenia: the role of recognition and visual discrimination deficits.

  2015cited by this paper
• Using a maternal immune stimulation model of schizophrenia to study behavioral and neurobiological alterations over the developmental course.

  2015cited by this paper
• Dissociable effects of NR2A and NR2B NMDA receptor antagonism on cognitive flexibility but not pattern separation

  2015influential reference
• Effects of nitric oxide-related compounds in the acute ketamine animal model of schizophrenia

  2015cited by this paper
• Improvement of Psychotic Symptoms and the Role of Tissue Plasminogen Activator

  2015cited by this paper
• Cognitive Impairment in Schizophrenia : The Great Unmet Need

  2015cited by this paper
• A computational model of pattern separation efficiency in the dentate gyrus with implications in schizophrenia

  2015cited by this paper
• Effects of D- and L-govadine on the disruption of touchscreen object-location paired associates learning in rats by acute MK-801 treatment

  2015cited by this paper
• In search of multimodal neuroimaging biomarkers of cognitive deficits in schizophrenia.

  2015cited by this paper
• Cognitive impairment in schizophrenia: the great unmet need

  2015cited by this paper
• Associate editor: F. TaraziClozapine and GABA transmission in schizophrenia disease models: Establishing principles to guide treatments

  2015cited by this paper
• Cascading and combined effects of cognitive deficits and residual symptoms on functional outcome in schizophrenia - A path-analytical approach.

  2015cited by this paper
• In vivo hippocampal subfield volumes in schizophrenia and bipolar disorder.

  2015cited by this paper
• Strain-dependent effects on acquisition and reversal of visual and spatial tasks in a rat touchscreen battery of cognition.

  2015influential reference
• Prefrontal cortex and the dysconnectivity hypothesis of schizophrenia

  2015cited by this paper
• Attenuation of MK-801-induced behavioral perseveration by typical and atypical antipsychotic pretreatment in rats.

  2015cited by this paper
• Effect of electroconvulsive seizures on pattern separation

  2015cited by this paper
• The Effects of Sodium Nitroprusside Treatment on Cognitive Deficits in Schizophrenia: A Pilot Study

  2015cited by this paper
• Nitroprusside single-dose prevents the psychosis-like behavior induced by ketamine in rats for up to one week.

  2015cited by this paper
• Prenatal immune challenge in rats: effects of polyinosinic-polycytidylic acid on spatial learning, prepulse inhibition, conditioned fear, and responses to MK-801 and amphetamine.

  2015cited by this paper
• Sodium nitroprusside, a nitric oxide donor for novel treatment of schizophrenia, may also modulate dopaminergic systems.

  2014cited by this paper
• Thinking and acting beyond the positive: the role of the cognitive and negative symptoms in schizophrenia

  2014influential reference
• Sodium nitroprusside in 2014: A clinical concepts review

  2014cited by this paper
• Loss of pattern separation performance in schizophrenia suggests dentate gyrus dysfunction.

  2014cited by this paper
• Ketamine, but not MK-801, produces antidepressant-like effects in rats responding on a differential-reinforcement-of-low-rate operant schedule

  2014cited by this paper
• Prefrontal Cortical GABA Modulation of Spatial Reference and Working Memory

  2014cited by this paper
• Schizophrenia: from dopaminergic to glutamatergic interventions.

  2014cited by this paper
• Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia

  2014cited by this paper
• Meta-analysis of cognitive performance in drug-naïve patients with schizophrenia.

  2014cited by this paper
• Cognitive deficits in youth with familial and clinical high risk to psychosis: a systematic review and meta‐analysis

  2014cited by this paper
• Lower expression of glutamic acid decarboxylase 67 in the prefrontal cortex in schizophrenia: contribution of altered regulation by Zif268.

  2014cited by this paper
• Different effects of the NMDA receptor antagonists ketamine, MK-801, and memantine on postsynaptic density transcripts and their topography: role of Homer signaling, and implications for novel antipsychotic and pro-cognitive targets in psychosis.

  2013cited by this paper
• Preclinical evaluation of non-imidazole histamine H3 receptor antagonists in comparison to atypical antipsychotics for the treatment of cognitive deficits associated with schizophrenia.

  2013cited by this paper
• The effects of an acute challenge with the NMDA receptor antagonists, MK-801, PEAQX, and ifenprodil, on social inhibition in adolescent and adult male rats

  2013cited by this paper
• Rapid improvement of acute schizophrenia symptoms after intravenous sodium nitroprusside: a randomized, double-blind, placebo-controlled trial.

  2013cited by this paper
• Pharmacological Interventions for the MATRICS Cognitive Domains in Schizophrenia: What’s the Evidence?

  2013cited by this paper
• Polymorphisms in the dopamine transporter gene are associated with visual hallucinations and levodopa equivalent dose in Brazilians with Parkinson's disease.

  2013cited by this paper
• Reduced but broader prefrontal activity in patients with schizophrenia during n-back working memory tasks: a multi-channel near-infrared spectroscopy study.

  2013cited by this paper
• Visuospatial working memory is impaired in an animal model of schizophrenia induced by acute MK-801: an effect of pretraining.

  2013cited by this paper
• Dissociation between memory retention across a delay and pattern separation following medial prefrontal cortex lesions in the touchscreen TUNL task

  2013cited by this paper
• Decreased levels of D-aspartate and NMDA in the prefrontal cortex and striatum of patients with schizophrenia.

  2013cited by this paper
• Acute N-methyl-D-aspartate receptor hypofunction induced by MK801 evokes sex-specific changes in behaviors observed in open-field testing in adult male and proestrus female rats.

  2013cited by this paper
• The touchscreen operant platform for testing working memory and pattern separation in rats and mice

  2013cited by this paper
• Capturing the angel in "angel dust": twenty years of translational neuroscience studies of NMDA receptor antagonists in animals and humans.

  2012influential reference
• Is the acute NMDA receptor hypofunction a valid model of schizophrenia?

  2012cited by this paper
• Face and body perception in schizophrenia: a configural processing deficit?

  2012cited by this paper
• From Revolution to Evolution: The Glutamate Hypothesis of Schizophrenia and its Implication for Treatment

  2012cited by this paper
• Abnormal functional activation and connectivity in the working memory network in early-onset schizophrenia.

  2012cited by this paper
• Working memory in the odor span task: effects of chlordiazepoxide, dizocilpine (MK801), morphine, and scopolamine

  2012cited by this paper
• NMDA receptor and schizophrenia: a brief history.

  2012cited by this paper
• New translational assays for preclinical modelling of cognition in schizophrenia: the touchscreen testing method for mice and rats.

  2012influential reference
• A NOS1 variant implicated in cognitive performance influences evoked neural responses during a high density EEG study of early visual perception

  2012cited by this paper
• Common and differential pathophysiological features accompany comparable cognitive impairments in medication-free patients with schizophrenia and in healthy aging subjects.

  2012cited by this paper
• Altered object-in-place recognition memory, prepulse inhibition, and locomotor activity in the offspring of rats exposed to a viral mimetic during pregnancy.

  2012cited by this paper
• Prenatal immune challenge in rats: Altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route‐based learning as a function of maternal body weight gain after prenatal exposure to poly IC

  2012cited by this paper
• The pharmacological sensitivity of a touchscreen-based visual discrimination task in the rat using simple and perceptually challenging stimuli

  2012cited by this paper
• Nitric oxide modulates apomorphine-induced recognition memory deficits in rats.

  2012cited by this paper
• The NOS1 variant rs6490121 is associated with variation in prefrontal function and grey matter density in healthy individuals

  2012cited by this paper
• Automatic recording of mediating behavior in delayed matching- and nonmatching-to-position procedures in rats

  2011cited by this paper
• Hippocampal synaptic activity, pattern separation and episodic-like memory: implications for mouse models of Alzheimer's disease pathology.

  2011cited by this paper
• Cortical deficits of glutamic acid decarboxylase 67 expression in schizophrenia: clinical, protein, and cell type-specific features.

  2011cited by this paper
• The hippocampal formation in schizophrenia.

  2010cited by this paper
• Glutamatergic theories of schizophrenia.

  2010cited by this paper
• Animal models of neuropsychiatric disorders

  2010cited by this paper
• Spatial localization deficits and auditory cortical dysfunction in schizophrenia.

  2010cited by this paper
• Trial-unique, delayed nonmatching-to-location (TUNL): A novel, highly hippocampus-dependent automated touchscreen test of location memory and pattern separation

  2010influential reference
• Removing Obstacles in Neuroscience Drug Discovery: The Future Path for Animal Models

  2009influential reference
• Strain differences in the distribution of N-methyl-d-aspartate and gamma (gamma)-aminobutyric acid-A receptors in rat brain.

  2009cited by this paper
• Alterations in functional activation in euthymic bipolar disorder and schizophrenia during a working memory task

  2009cited by this paper
• Subchronic MK-801 behavioural deficits in rats: partial reversal by the novel nitrate GT 1061.

  2009cited by this paper
• Is there a cortical blood flow redistribution pattern related with perseverative error in schizophrenia?

  2009cited by this paper
• Neurocognition in first-episode schizophrenia: a meta-analytic review.

  2009cited by this paper
• Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects.

  2009cited by this paper
• Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia.

  2009cited by this paper
• Differential Contributions of Prefrontal and Hippocampal Dopamine D1 and D2 Receptors in Human Cognitive Functions

  2008cited by this paper
• Hippocampal dysfunction and disruption of dopamine system regulation in an animal model of schizophrenia

  2008cited by this paper
• A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats

  2008cited by this paper
• Ketamine, But Not Phencyclidine, Selectively Modulates Cerebellar GABAA Receptors Containing α6 and δ Subunits

  2008cited by this paper
• Executive deficits in psychotic and bipolar disorders – Implications for our understanding of schizoaffective disorder

  2008cited by this paper
• Schizophrenia: a concise overview of incidence, prevalence, and mortality.

  2008influential reference
• The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments.

  2007cited by this paper
• Neuroimaging of cognitive disability in schizophrenia: Search for a pathophysiological mechanism

  2007cited by this paper
• Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations.

  2006influential reference
• Glutamatergic drugs for schizophrenia.

  2006cited by this paper
• Targeting the dopamine D2 receptor in schizophrenia

  2006cited by this paper
• Double dissociation between hippocampal and prefrontal lesions on an operant delayed matching task and a water maze reference memory task.

  2006cited by this paper
• First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patients

  2006cited by this paper
• Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition

  2006cited by this paper
• Specificity of prefrontal dysfunction and context processing deficits to schizophrenia in never-medicated patients with first-episode psychosis.

  2005cited by this paper
• Working memory impairments in schizophrenia: a meta-analysis.

  2005cited by this paper
• Cortical inhibitory neurons and schizophrenia

  2005influential reference
• Comparison of error patterns produced by scopolamine and MK-801 on repeated acquisition and transition baselines

  2005cited by this paper
• Maintenance and manipulation of information in schizophrenia: further evidence for impairment in the central executive component of working memory.

  2004cited by this paper
• Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria.

  2004cited by this paper
• Identification of separable cognitive factors in schizophrenia.

  2004cited by this paper

• The impact of response latency on working memory assessment in mice.

  2025cites this paper
• Glutamatergic and GABAergic Receptor Modulation Present Unique Electrophysiological Fingerprints in a Concentration-Dependent and Region-Specific Manner

  2023cites this paper
• Decision Making in Mice During an Optimized Touchscreen Spatial Working Memory Task Sensitive to Medial Prefrontal Cortex Inactivation and NMDA Receptor Hypofunction

  2022cites this paper
• The effects of acute Cannabis smoke or Δ9-THC injections on the trial-unique, nonmatching-to- location and five-choice serial reaction time tasks in male Long-Evans rats.

  2022cites this paper
• The Touchscreen‐Based Trial‐Unique, Nonmatching‐To‐Location (TUNL) Task as a Measure of Working Memory and Pattern Separation in Rats and Mice

  2021cites this paper
• Striatum-projecting prefrontal cortex neurons support working memory maintenance

  2021cites this paper
• The Nitric Oxide (NO) Donor Sodium Nitroprusside (SNP) and Its Potential for the Schizophrenia Therapy: Lights and Shadows

  2021cites this paper
• Task phase‐specific involvement of the rat posterior parietal cortex in performance of the TUNL task

  2020cites this paper
• MK-801 impairs working memory on the Trial-Unique Nonmatch-to-Location test in mice, but this is not exclusively mediated by NMDA receptors on PV+ interneurons or forebrain pyramidal cells.

  2020cites this paper
• ChABC infusions into medial prefrontal cortex, but not posterior parietal cortex, improve the performance of rats tested on a novel, challenging delay in the touchscreen TUNL task

  2020cites this paper
• Translation-Focused Approaches to GPCR Drug Discovery for Cognitive Impairments Associated with Schizophrenia.

  2020cites this paper
• Effects of the cannabinoid receptor 1 positive allosteric modulator GAT211 and acute MK-801 on visual attention and impulsivity in rats assessed using the five-choice serial reaction time task.

  2020cites this paper
• An Overview of Animal Models Related to Schizophrenia

  2019cites this paper
• The mGluR2/3 agonist LY379268 reverses NMDA receptor antagonist effects on cortical gamma oscillations and phase coherence, but not working memory impairments, in mice

  2019cites this paper
• Effects of sodium nitroprusside in the acute dizocilpine (MK-801) animal model of schizophrenia.

  2019cites this paper
• Performance of the trial‐unique, delayed non‐matching‐to‐location (TUNL) task depends on AMPA/Kainate, but not NMDA, ionotropic glutamate receptors in the rat posterior parietal cortex

  2019cites this paper
• Examining the Roles of Thalamocortical and Frontoparietal Circuitry for Working Memory in the Rat

  2019influential citation
• The role of striatum and prefrontal cortex in the prevention of amphetamine‐induced schizophrenia‐like effects mediated by nitric oxide compounds

  2018cites this paper
• Medial prefrontal cortex and dorsomedial striatum are necessary for the trial-unique, delayed nonmatching-to-location (TUNL) task in rats: role of NMDA receptors

  2017cites this paper
• A non-ionotropic activity of NMDA receptors contributes to glycine-induced neuroprotection in cerebral ischemia-reperfusion injury

  2017cites this paper
• Improvement of Psychotic Symptoms and the Role of Tissue Plasminogen Activator

  2015cites this paper