Mechanism(s) involved in opioid drug abuse modulation of HAND.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Current HIV Research

• Publication date

  2012-06-30

• Fields of study

  Medicine

• Identifiers
  DOI 10.2174/157016212802138805PMID 22591371PMCID PMC3565579
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2011cited by this paper
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  2011cited by this paper
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• Immunosuppressive Effects of Opioids—Clinical Relevance

  2011cited by this paper
• Morphine potentiates neurodegenerative effects of HIV-1 Tat through actions at μ-opioid receptor-expressing glia.

  2011cited by this paper
• Toll-Like Receptor 9 Is Required for Opioid-Induced Microglia Apoptosis

  2011cited by this paper
• A Growth Factor Attenuates HIV-1 Tat and Morphine Induced Damage to Human Neurons: Implication in HIV/AIDS-Drug Abuse Cases

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  2011cited by this paper
• Opioid Drug Abuse and Modulation of Immune Function: Consequences in the Susceptibility to Opportunistic Infections

  2011cited by this paper
• Prevention of HIV infection among injection drug users in resource-limited settings.

  2010cited by this paper
• Morphine induces the release of CCL5 from astrocytes: Potential neuroprotective mechanism against the HIV protein gp120

  2010cited by this paper
• Critical Role of Toll-Like Receptor 9 in Morphine and Mycobacterium tuberculosis–Induced Apoptosis in Mice

  2010cited by this paper
• HIV prevention, treatment, and care services for people who inject drugs: a systematic review of global, regional, and national coverage.

  2010cited by this paper
• Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons.

  2010cited by this paper
• HIV-Associated Neurocognitive Disorder: Pathogenesis and Therapeutic Opportunities

  2010cited by this paper
• Morphine enhances Tat-induced activation in murine microglia

  2009cited by this paper
• Morphine and HIV‐Tat increase microglial‐free radical production and oxidative stress: possible role in cytokine regulation

  2009cited by this paper
• Tight Junction Regulation by Morphine and HIV-1 Tat Modulates Blood–Brain Barrier Permeability

  2008influential reference
• Morphine Exacerbates HIV-1 Tat-Induced Cytokine Production in Astrocytes through Convergent Effects on [Ca2+]i, NF-κB Trafficking and Transcription

  2008cited by this paper
• GTPγS Incorporation in the Rat Brain: A Study on μ-Opioid Receptors and CXCR4

  2008cited by this paper
• Cell‐specific actions of HIV‐Tat and morphine on opioid receptor expression in glia

  2008cited by this paper
• Opiate modulation of IL-1alpha, IL-2, and TNF-alpha transport across the blood-brain barrier.

  2008influential reference
• DAMGO‐induced expression of chemokines and chemokine receptors: the role of TGF‐β1

  2008cited by this paper
• HIV and antiretroviral therapy in the brain: neuronal injury and repair

  2008cited by this paper
• Glial toll-like receptor signaling in central nervous system infection and autoimmunity.

  2008cited by this paper
• Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review.

  2008cited by this paper
• Morphine Induces Defects in Early Response of Alveolar Macrophages to Streptococcus pneumoniae by Modulating TLR9-NF-κB Signaling1

  2008cited by this paper
• Systemic infections and inflammation affect chronic neurodegeneration

  2007cited by this paper
• Toll-like receptor 2 mediates CNS injury in focal cerebral ischemia.

  2007cited by this paper
• Clinical care of the HIV-infected drug user.

  2007cited by this paper
• Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

  2007cited by this paper
• Toll-Like Receptor 2 Signaling in Response to Brain Injury: An Innate Bridge to Neuroinflammation

  2006cited by this paper
• Naltrexone inhibits alcohol‐mediated enhancement of HIV infection of T lymphocytes

  2006cited by this paper
• CCR2 mediates increases in glial activation caused by exposure to HIV-1 Tat and opiates.

  2006cited by this paper
• Innate and adaptive immune responses of the central nervous system.

  2006cited by this paper
• Mechanisms of Neuroimmunity and Neurodegeneration Associated with HIV-1 Infection and AIDS

  2006cited by this paper
• Regulation of neural cell survival by HIV-1 infection.

  2006cited by this paper
• Microglia as a Pharmacological Target in Infectious and Inflammatory Diseases of the Brain

  2006cited by this paper
• Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis.

  2006cited by this paper
• Abuse of prescription drugs and the risk of addiction.

  2006cited by this paper
• HIV‐1 Tat and opiate‐induced changes in astrocytes promote chemotaxis of microglia through the expression of MCP‐1 and alternative chemokines

  2006cited by this paper
• Imaging of neuro-AIDS.

  2006cited by this paper
• Detection of HHV-6B in post-mortem central nervous system tissue of a post-bone marrow transplant recipient: a multi-virus array analysis

  2006cited by this paper
• Association between Dementia and Infectious Disease: Evidence from a Case-Control Study

  2005cited by this paper
• Synergistic increases in intracellular Ca2+, and the release of MCP‐1, RANTES, and IL‐6 by astrocytes treated with opiates and HIV‐1 Tat

  2005cited by this paper
• Morphine inhibits CD8+ T cell‐mediated, noncytolytic, anti‐HIV activity in latently infected immune cells

  2005cited by this paper
• Morphine exacerbates HIV-1 viral protein gp120 induced modulation of chemokine gene expression in U373 astrocytoma cells.

  2005cited by this paper
• The neuropathogenesis of AIDS

  2005cited by this paper
• Molecular mechanisms of HIV-1 associated neurodegeneration

  2005cited by this paper
• Morphine modulates chemokine gene regulation in normal human astrocytes.

  2005influential reference
• Morphine Impairs Host Innate Immune Response and Increases Susceptibility to Streptococcus pneumoniae Lung Infection1

  2005cited by this paper
• In response to pathogens, glial cells dynamically and differentially regulate Toll-like receptor gene expression.

  2005influential reference
• HIV-1 gp120 Proteins Alter Tight Junction Protein Expression and Brain Endothelial Cell Permeability: Implications for the Pathogenesis of HIV-Associated Dementia

  2005cited by this paper
• The Beta Chemokines CCL4 and CCL5 Enhance Adhesion of Specific CD4+ T Cell Subsets to Human Brain Endothelial Cells

  2004cited by this paper
• The CC chemokine ligand 3 regulates CD11c+CD11b+CD8α− dendritic cell maturation and activation following viral infection of the central nervous system: implications for a role in T cell activation

  2004cited by this paper
• Stimulation of toll‐like receptor 2 in mononuclear cells from HIV‐infected patients induces chemokine responses: possible pathogenic consequences

  2004cited by this paper
• Human Immunodeficiency Virus Type 1 Infection of Human Brain-Derived Progenitor Cells

  2004cited by this paper
• Differences in HIV Disease Progression by Injecting Drug Use in HIV-Infected Persons in Care

  2004cited by this paper
• Increased expression of toll-like receptor 2 on monocytes in HIV infection: possible roles in inflammation and viral replication.

  2004cited by this paper
• Systemic infection, interleukin 1β, and cognitive decline in Alzheimer’s disease

  2003cited by this paper
• Pathogenesis of human immunodeficiency virus-induced neurological disease

  2003cited by this paper
• HIV‐1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells

  2003cited by this paper
• Chemokine Expression by Glial Cells Directs Leukocytes to Sites of Axonal Injury in the CNS

  2003cited by this paper
• Mu-opioid modulation of HIV-1 coreceptor expression and HIV-1 replication.

  2003cited by this paper
• HIV‐1 gp120 Proteins and gp160 Peptides Are Toxic to Brain Endothelial Cells and Neurons: Possible Pathway for HIV Entry into the Brain and HIV‐Associated Dementia

  2002cited by this paper
• Human Immunodeficiency Virus Type 1 Enters Brain Microvascular Endothelia by Macropinocytosis Dependent on Lipid Rafts and the Mitogen-Activated Protein Kinase Signaling Pathway

  2002cited by this paper
• Prevalence of Tuberculosis Infection and Comparison of Multiple-puncture Liquid Tuberculin Test and Mantoux Test Among Drug Users

  2002cited by this paper
• Methadone induces CCR5 and promotes AIDS virus infection

  2002cited by this paper
• Human immunodeficiency virus (HIV) proteins in neuropathogenesis of HIV dementia.

  2002cited by this paper
• Molecular Basis for Interactions of HIV and Drugs of Abuse

  2002cited by this paper
• Broad Expression of Toll‐Like Receptors in the Human Central Nervous System

  2002cited by this paper
• Neuroimmune and neurovirological aspects of human immunodeficiency virus infection.

  2001cited by this paper
• Toll‐like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram‐negative bacterial cell wall components

  2001cited by this paper
• Differences in HIV disease progression by injection drug use and by sex in the era of highly active antiretroviral therapy

  2001cited by this paper
• Morphine inhibits human microglial cell production of, and migration towards, RANTES

  2000cited by this paper
• Morphine Induces Gene Expression of CCR5 in Human CEM x174 Lymphocytes*

  2000cited by this paper
• HIV-1-associated central nervous system dysfunction.

  2000cited by this paper
• Neuronal apoptosis does not correlate with dementia in HIV infection but is related to microglial activation and axonal damage

  1999cited by this paper
• HIV infection of fetal human astrocytes: the potential role of a receptor-mediated endocytic pathway.

  1999cited by this paper
• Self-reported antiretroviral therapy in injection drug users.

  1998cited by this paper
• Barriers to use of free antiretroviral therapy in injection drug users.

  1998cited by this paper
• The effects of human immunodeficiency virus in the central nervous system.

  1998cited by this paper
• HIV‐1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix‐associated heparan sulfate proteoglycans through its basic region

  1997cited by this paper
• Astrocytic adhesion molecules are increased in HIV‐1‐associated cognitive/motor complex

  1997cited by this paper
• Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection.

  1997cited by this paper
• AIDS Dementia Is Associated with Massive, Activated HIV-1 Infection and Concomitant Expression of Several Cytokines

  1996cited by this paper
• Localization of HIV‐1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry

  1996cited by this paper
• Cellular reservoirs of HIV‐1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry

  1996cited by this paper
• Dementia Associated with the Acquired Immunodeficiency Syndrome

  1995cited by this paper
• Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia

  1995cited by this paper
• Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome.

  1995influential reference
• In situ detection of polymerase chain reaction-amplified HIV-1 nucleic acids and tumor necrosis factor-alpha RNA in the central nervous system.

  1994cited by this paper
• Detection of HIV-1 DNA in pediatric AIDS brain tissue by two-step ISPCR.

  1994cited by this paper
• HIV‐1 mRNA Transcripts from Persistently Infected Human Fetal Astrocytes

  1993cited by this paper
• The fine structure of acquired immunodeficiency syndrome encephalopathy.

  1989cited by this paper
• Human immunodeficiency virus in brain biopsies of patients with AIDS and progressive encephalopathy.

  1987cited by this paper
• Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.

  1986cited by this paper

• Time since HIV diagnosis is linked to amnestic mild cognitive impairment (MCI) in older adults with HIV

  2025cites this paper
• Examining the effects of the HIV‐1 protein Tat and morphine on antiretroviral accumulation and distribution within the brain

  2024cites this paper
• Fentanyl dysregulates neuroinflammation and disrupts blood-brain barrier integrity in HIV-1 Tat transgenic mice

  2024cites this paper
• Crossroads of Drug Abuse and HIV Infection: Neurotoxicity and CNS Reservoir

  2022cites this paper
• Comparison of Psychopathologic Characteristics between Individuals Undergoing Methadone Maintenance Treatment, Opioid Dependents, and Control Group

  2022cites this paper
• Buprenorphine reverses neurocognitive impairment in EcoHIV infected mice: A potential therapy for HIV-NCI

  2022cites this paper
• Opioid use disorder and the brain: a clinical perspective.

  2021cites this paper
• Brain-Accumulating Nanoparticles for Assisting Astrocytes to Reduce Human Immunodeficiency Virus and Drug Abuse-Induced Neuroinflammation and Oxidative Stress.

  2021cites this paper
• Synergistic Effect and Mechanism of Apoptosis Induction by Morphine and the HIV-1gp120V3 Loop in Hippocampal Neurons

  2021cites this paper
• Opioid and neuroHIV Comorbidity – Current and Future Perspectives

  2020cites this paper
• Morphine‐mediated release of miR‐138 in astrocyte‐derived extracellular vesicles promotes microglial activation

  2020cites this paper
• Cognitive Impairment among People Who Use Heroin and Fentanyl: Findings from the Miami Adult Studies on HIV (MASH) Cohort

  2020cites this paper
• Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids

  2020cites this paper
• Opioid-Mediated HIV-1 Immunopathogenesis

  2020influential citation
• HIV-Tat and Cocaine Impact Brain Energy Metabolism: Redox Modification and Mitochondrial Biogenesis Influence NRF Transcription-Mediated Neurodegeneration

  2020cites this paper
• HIV-1 TAT Interactions with Opioids are Modulated by Progesterone and Estradiol

  2020cites this paper
• HIV-1 Tat and opioids act independently to limit antiretroviral brain concentrations and reduce blood–brain barrier integrity

  2019cites this paper
• Opioid and Chemokine Regulation of Cortical Synaptodendritic Damage in HIV-Associated Neurocognitive Disorders.

  2019cites this paper
• Cell-type specific differences in antiretroviral penetration and the effects of HIV-1 Tat and morphine among primary human brain endothelial cells, astrocytes, pericytes, and microglia.

  2019cites this paper
• The Effects of Opioids on HIV Neuropathogenesis

  2019influential citation
• Structural and Functional Consequences of HIV-1 Viral Protein Tat and Morphine Co-Exposure at the Blood-Brain Barrier

  2018cites this paper
• Frontline Science: Buprenorphine decreases CCL2‐mediated migration of CD14+CD16+ monocytes

  2018cites this paper
• Immunomodulatory Role of Complement Proteins in the Neuropathology Associated with Opiate Abuse and HIV-1 Co-Morbidity

  2017cites this paper
• HIV-1 gp 120 and morphine induced oxidative stress : role in cell cycle regulation

  2017cites this paper
• HIV-Associated Neurocognitive Disorders

  2017cites this paper
• Opioids and Opioid Maintenance Therapies: Their Impact on Monocyte-Mediated HIV Neuropathogenesis.

  2016cites this paper
• Effect of chronic morphine administration on circulating dendritic cells in SIV-infected rhesus macaques.

  2016cites this paper
• A novel role for and potential therapeutic targeting of heme oxygenase-1 in HIV neuropathogenesis

  2015cites this paper
• HIV-1 gp120 and morphine induced oxidative stress: role in cell cycle regulation

  2015cites this paper
• Sex differences in outcomes of methadone maintenance treatment for opioid use disorder: a systematic review and meta-analysis.

  2015cites this paper
• Chronic morphine and HIV-1 Tat promote differential central nervous system trafficking of CD3+ and Ly6C+ immune cells in a murine Streptococcus pneumoniae infection model

  2015cites this paper
• Blood-brain barrier and neuro-AIDS.

  2015cites this paper
• Atención clínica integral y pronóstico de pacientes con abuso de drogas e infección por el VIH

  2015cites this paper
• Drugs of Abuse in HIV infection and neurotoxicity

  2015cites this paper
• Interactions of HIV and drugs of abuse: the importance of glia, neural progenitors, and host genetic factors.

  2014influential citation
• Barriers to treatment of substance abuse in developing countries

  2014cites this paper
• Chronic Inflammation and the Role for Cofactors (Hepatitis C, Drug Abuse, Antiretroviral Drug Toxicity, Aging) in HAND Persistence

  2014cites this paper
• Drugs of Abuse and NeuroAIDS: Opiates

  2014cites this paper
• Brain viral burden, neuroinflammation and neurodegeneration in HAART-treated HIV positive injecting drug users

  2014cites this paper
• Latest trends in drugs of abuse - HIV infection and neuroAIDS.

  2013cites this paper